Jacobo SITT

Jacobo SITT

@jdsitt.bsky.social

Researcher Neuroscience of Consciousness. Directeur Recherche INSERM. Physicist, psychiatrist. 4 children juggler. @jordansGAngels parent ๐Ÿ‡ฆ๐Ÿ‡ท๐Ÿ‡ซ๐Ÿ‡ท

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Great work from Emilia exploring attentional focus. This could be an interesting avenue to explore DoC patients. The rest of the amazing work that Emilia did during her PhD will soon go out. Stay attentive!

Emi Flรณ@em-fl.bsky.social

1/ ๐ŸŽ‰ Thrilled to share part of my PhD work published in @PNAS_Nexus! ๐ŸŒ This collaboration spanned France, Italy, and Uruguay. We explored how brain-heart interactions reveal attentional focusโ€”insights relevant to patients with #DisordersOfConsciousness (DoC). ๐Ÿ”— academic.oup.com/pnasnexus/ar...

I am happy to return to Bluesky to promote Dragana's work. Her work is a tour-de-force that demonstrates the importance of multimodal assessment of patients with disorders of consciousness. Thanks to all the EraBrain consortium partners behind this project. @ERANET_PerMed

Dragana Manasova@d-manasova.bsky.social

1/ Excited to share a part of my PhD in our new preprint: Integrative Electrophysiology and Neuroimaging Approach in Assessing Disorders of Consciousness: A Multimodal Multicentric Machine Learning Study #DoC #MachineLearning #Multimodal medrxiv.org/cgi/content/... A ๐Ÿงต...

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Our results reveal a bidirectional influence between ongoing brain dynamics and conscious perception. Moreover, they suggest that certain brain configurations favor conscious processing of external stimuli, highlighting their functional role in shaping conscious content. (7/8)

In the future, targeting these moments of favorable patterns in patients with disorders of consciousness may help us identify windows of greater receptivity to the external world, paving the way for developing individualized patient care protocols. (8/8)

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We hypothesized that participants would be more likely to detect a stimulus at threshold if they exhibited this pattern that is most typical of conscious states (Pattern 1). As expected, detection rates were higher when Pattern 1 occurred during the stimulus presentation! (5/8)

Interestingly, the occurrence of Pattern 1 increased following the detection of a threshold stimulus, indicating that participants were more prone to transitioning to this pattern, which seems to be favorable for conscious perception, when they detected the stimulus. (6/8)

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Importantly the overall volume of the stimuli was adjusted for each participant in a staircase session prior to the task so that the middle SNR (SNR-9) would be detected in only half of the trials. (3/8)

Using phase-based functional connectivity and k-means clustering we computed recurrent brain patterns. Our patterns closely matched those found by Demertzi et al. (2019), with Pattern 1 corresponding to the pattern typical of conscious states, decreasing with unconsciousness. (4/8)

Participants performed an auditory detection task during fMRI acquisitions. They were asked to detect a French vowel /a/ embedded in continuous background noise at different signal-to-noise ratios (SNR). (2/8)

I'm so happy that my first relevant message here is our collaboration with Delphine Oudiette studying the limits of responsiveness in all stages of sleep. Congrats to all authors in particular one of the leading, the fresh new PhD Basak Turker.

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