Jukka-Pekka Verta

Jukka-Pekka Verta

@jpverta.bsky.social

Functional & evolutionary genomics β€’ Associate Professor Nord University πŸ‡³πŸ‡΄ β€’ Fish aficionado β€’ Living above the Arctic Circle FEG lab: https://feg-lab.github.io

1K followers1K following98 posts

Jukka-Pekka Verta reposted

Jukka-Pekka Verta reposted

Jukka-Pekka Verta reposted

We are often asked whether pangenomes are worth the hassle. The files can be large and methods to explore them are much more challenging than linear references. Earlier this week, we preprinted a clear example of how and why pan-genome graphs are so important for trait discovery.

bioRxiv Genomics@biorxiv-genomic.bsky.social

Dissecting the regulatory and genomic drivers of the dichogamy determining G-locus in pecan https://www.biorxiv.org/content/10.64898/2026.05.14.725045v1

Jukka-Pekka Verta reposted

Our latest paper on building models of cell fate decisions -with David Rand, Marine Fontaine & @joadelas.bsky.social- combines developmental biology, dynamical systems theory and bioinformatics. I wrote a short piece to summarise it & explain ideas behind the approach briscoelab.org/blog-quantif...

briscoelab.orgQuantifying Waddington's Landscape | Briscoe LabI have written before about how two conceptual frameworks have shaped our thinking about cell fate, Waddington's epigenetic landscape and Davidson's gene...

Jukka-Pekka Verta reposted

We have a new #preprint on #lunar #reproductive #timing as a #magictrait in #speciation www.biorxiv.org/content/10.6... with former PhD students Alexander Jacobsen πŸ§ͺπŸ’» Runa Ekrem 🦟🌊 πŸ™ Big thanks to both for the great work! #EvoBio #barriers #Chronobiology #circadian #MarineEcology

Jukka-Pekka Verta reposted

πŸ§¬πŸ”¬ Why are enhancers transcribed and how does that impact gene regulation? I’m really excited to share our new paper in @science.org showing that noncoding RNAs control the timing of gene activation in embryos. With Mike Levine #ScienceResearch @columbiamed.bsky.social A few highlights below... πŸ§΅πŸ‘‡

science.orgNoncoding transcription controls the developmental dynamics of long-range gene regulationThe genomic regions regulating gene expression are often themselves transcribed into a variety of noncoding RNAs (ncRNAs). However, the regulatory roles of this noncoding transcription remain largely ...

Jukka-Pekka Verta reposted

🚨My first PhD chapter is now out on bioRxiv ! A 🧡 1/n

bioRxiv Genomics@biorxiv-genomic.bsky.social

Elevated isoform richness in males largely reflects transcriptional noise rather than proteomic complexity https://www.biorxiv.org/content/10.64898/2026.08.10.744030v1

Jukka-Pekka Verta reposted

Jukka-Pekka Verta reposted

Jukka-Pekka Verta reposted

(1/10) The majority of human genetic variation is located in non-coding regions. The great challenge of the post-genomic era is to assign function to these variants. We reasoned that combining haplotyping with allele-specific multiomics can help pinpoint the functional ones: rdcu.be/fgr5W. A thread:

rdcu.beMapping functional non-coding variation in individual human genomes through haplotyping, multiomics, and deep learningNature Communications - How non-coding mutations in DNA contribute to phenotypes is a largely unresolved question. Here the authors integrate personal genomics and machine learning to identify...

Our brilliant PhD students are at #SMBE2026 ! S22: P334 Rachel Carboni with snMultiomics S22: P339 @xindih.bsky.social with epistasis vs modularity in GRNs (w/ @fishcongen.bsky.social) S22: talk at 17:45 @jennisiren.bsky.social with GxE in gene expression (w/ main sup @pyhatanja.bsky.social)

#SMBE2026 S22: Evolution of gene regulation: insights from novel molecular and statistical approaches πŸ—“οΈ Wed Jul 1, 1:20pm - Part 1 πŸ—“οΈ Wed Jul 1, 3:50pm - Part 2 πŸ”— smbe2026.org/programme

Jukka-Pekka Verta reposted

Published version @pnas.org of our collaborative work with Talia Karasov Lab (tkarasovlab.org) et al., πŸ§΅πŸ‘‡ www.pnas.org/doi/10.1073/... @cloeucl.bsky.social @ugiatucl.bsky.social @ucllifesciences.bsky.social @uofubiology.bsky.social #microsky #phagesky

HernΓ‘n A. Burbano@hernanaburbano.bsky.social

Our new collaborative work led by @taliamycota.bsky.social Jiajun Cui & Emma Caullireau between my lab @ucllifesciences.bsky.social @cloeucl.bsky.social & the Karasov Lab (tkarasovlab.org) @uofubiology.bsky.social and collaborators: @plantricia.bsky.social et al. tinyurl.com/5yx2wmz5 (1/n)

Jukka-Pekka Verta reposted

Exciting breakthrough technology from the lab, now live in @cellcellpress.bsky.social ! Instead of cutting the genome where proteins bind (e.g., Cut&Tag), D&D-seq scars the DNA with a deaminase, allowing single cell genome mapping of TFs and chromatin remodellers!

Jukka-Pekka Verta reposted

1/6) What if aging begins, in part, as a bargain made in youth? In turquoise killifish, editing vgll3β€”a gene linked to puberty-timing in humans and salmonβ€”revealed one of the first causal single-gene examples of antagonistic pleiotropy in vertebrate aging 🧡

Jukka-Pekka Verta reposted

Twenty five years on from Dolph Schluter's book "The Ecology of Adaptive Radiation" that reshaped the way adaptive radiation was studied, this review revisits key questions raised to evaluate the progress made over the past quarter century, 8 of which remain unresolved...🌍πŸ§ͺπŸ‘‡

doi.orgβ€˜The ecology of adaptive radiation’ revisited: A 25-year reflectionAbstract. Twenty-five years ago, the book The Ecology of Adaptive Radiation by Dolph Schluter presented a testable framework that integrated ecology, genet

Jukka-Pekka Verta reposted

New TREE paper led by Jana Nickel on 'Hitchhiking of deleterious mutations within chromosomal inversions' doi.org/10.1016/j.tr... Broadly, if inversions are linked to an adaptive trait, homokaryotypes are at high frequency, and purging can reduce deleterious mutation load.....

Jukka-Pekka Verta reposted

Heidbreder et al. leveraged natural hybrids of wood ant species to highlight the underappreciated impact of Bateson-Dobzhansky-Muller incompatibility connectivity on the persistence of reproductive barriers over time. πŸ”— doi.org/10.1093/molbev/msag063 #evobio #molbio #speciation

doi.orgGenomic incompatibilities are persistent barriers when speciation happens with gene flow in Formica antsAbstract. A current goal of speciation research is identifying loci underlying reproductive barriers between species. Locating barrier loci in population g

Jukka-Pekka Verta reposted

Join us in wishing a massive happy 100th birthday to the man who has inspired millions of people around the world to care about nature and look after our planet - the incredible Sir David Attenborough! πŸŽ‰

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Jukka-Pekka Verta reposted

Ongoing DFO cuts to the Genomics Program and across the organization further compromise the capacity to conduct critical research evaluating the impacts of cumulative stressors and pathogens on salmon survival and to aid in the conservation of imperiled stocks πŸ§ͺπŸŒŽπŸŒπŸ¦‘πŸŸ thetyee.ca/News/2026/04...

thetyee.caSalmon Scientists Warn the DFO Is Killing a Crucial Lab | The TyeeThe genomics program opened up the β€˜black box’ of wild fish research. Former and current staff say it’s been gutted.

Jukka-Pekka Verta reposted

Our new paper is officially out in @newphyt.bsky.social! We disentangle how plants balance the trade-offs between rapid growth and water conservation. We found that Cape Verde Arabidopsis use a highly coordinated drought escape strategy driven by pleiotropic genes.

New Phytologist@newphyt.bsky.social

The genetic basis of multi-trait drought escape in colonizing A. thaliana lineages Elfarargi et al. @ahmedelfarargi.bsky.social @ahancock.bsky.social @apmweber.bsky.social @mpipz.bsky.social @trr341.bsky.social @ceplas.bsky.social nph.onlinelibrary.wiley.com/doi/10.1111/...

Jukka-Pekka Verta reposted

Jukka-Pekka Verta reposted

Safe to say that we are very excited about this here at ESEB! Huge thanks to Brian Golding for entrusting us with the fantastic service that you have created and curated for the years! Follow @evoldir.bsky.social

EvolDir@evoldir.bsky.social

πŸ“£ EvolDir is now managed by @eseb.bsky.social! We are delighted to be taking the reins and express our gratitude to both Brian Golding who began this service to the community in the mid-1980s and to @rdmpage.bsky.social who ran this account until now πŸ‘ You can now find evoldir here: evoldir.net

Jukka-Pekka Verta reposted