lyons-lab.bsky.social

lyons-lab.bsky.social

@lyons-lab.bsky.social

541 followers491 following11 posts

lyons-lab.bsky.social
@lyons-lab.bsky.social

Latest offering. How myelin ensheathes axons! Born from chat with Dwight Bergles on "weird things" we saw oligodendrocytes do, like making "bridges" between sheaths. Driven forward by Cody Call, Kelly Monk, and myelin folks @edinburgh-uni.bsky.social Enjoy! www.nature.com/articles/s41...

nature.comFlexible ensheathment of axons enables myelination of complex CNS networks - NatureThe rate of axon ensheathment varies within individual myelinating processes, resulting in chains of myelin sheaths connected by bridges consisting of thin cytoplasmic processes that provide&nbsp...

lyons-lab.bsky.social reposted

Julia van de Korput
@juliavdkorput.bsky.social

Thrilled that our paper is now published. It’s been a real privilege to work on this project together with co-first author @ara-donia.bsky.social, under the supervision of @lyons-lab.bsky.social, and with such an outstanding team in Edinburgh and internationally! www.science.org/doi/10.1126/...

science.orgMyelin sheaths in the central nervous system can withstand damage and dynamically remodelMyelin damage is a hallmark of several neurological disorders, but how it occurs remains to be fully understood. In this study, we found that early damage in zebrafish and rodent demyelination models ...

lyons-lab.bsky.social reposted

ara-donia.bsky.social
@ara-donia.bsky.social

I am delighted to see this work published. A big thanks to everyone, particularly the excellent supervision of @lyons-lab.bsky.social, the work of co-first author @juliavdkorput.bsky.social and wonderful collaborators in Amsterdam and Oregon. www.science.org/doi/10.1126/...

science.orgMyelin sheaths in the central nervous system can withstand damage and dynamically remodelMyelin damage is a hallmark of several neurological disorders, but how it occurs remains to be fully understood. In this study, we found that early damage in zebrafish and rodent demyelination models ...
lyons-lab.bsky.social
@lyons-lab.bsky.social

Latest from the lab, led by @ara-donia.bsky.social and @juliavdkorput.bsky.social Huge team effort, with immense contributions by friends from nearby and around the globe. www.science.org/doi/10.1126/...

science.orgMyelin sheaths in the central nervous system can withstand damage and dynamically remodelMyelin damage is a hallmark of several neurological disorders, but how it occurs remains to be fully understood. In this study, we found that early damage in zebrafish and rodent demyelination models ...

lyons-lab.bsky.social reposted

Jenn Orthmann Murphy
@jennoligomyelin.bsky.social

alert! fundamental myelin biology - led by the amazing Yevgeniya Mironova and Dwight Bergles www.science.org/doi/10.1126/...

science.orgMyelin is repaired by constitutive differentiation of oligodendrocyte progenitorsOligodendrocytes form myelin sheaths around axons to enable rapid signaling within neural circuits. The generation of new oligodendrocytes through differentiation of oligodendrocyte precursor cells (O...
lyons-lab.bsky.social
@lyons-lab.bsky.social

Fun to have contributed a little to this, led by the team of the incomparable Guoqiang Yu. Suspect that this will prove to be an immensely popular image analysis platform for interrogation of dynamic signallingl! www.sciencedirect.com/science/arti...

sciencedirect.comFast, accurate, and versatile data analysis platform for the quantification of molecular spatiotemporal signalsOptical recording of intricate molecular dynamics is becoming an indispensable technique for biological studies, accelerated by the development of new…

lyons-lab.bsky.social reposted

Philip Hasel
@philiphasel.bsky.social

Our paper on the superficial glia limitans is now published - huge thank you to all co-authors that helped getting this work across the finish line! www.cell.com/cell-reports...

cell.comDefining the molecular identity and morphology of glia limitans superficialis astrocytes in vertebratesHasel et al. show that molecularly and morphologically specialized astrocytes make up the brain and spinal cord surface, thereby creating the glia limitans superficialis. These astrocytes selectively ...
lyons-lab.bsky.social
@lyons-lab.bsky.social

First post at this side. Latest axon diameter action led by Jenea Bin, in collaboration with Nolan, Mobius, Monk, Werner, and Emery labs. www.biorxiv.org/content/10.1...

biorxiv.orgDevelopmental axon diameter growth of central nervous system axons does not depend on ensheathment or myelination by oligodendrocytesMyelination facilitates the rapid conduction of action potentials along axons. In the central nervous system (CNS), myelinated axons vary over 100-fold in diameter, with conduction speed scaling linea...

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