Fully funded 4-year PhD opportunity @lsiexeter.bsky.social &Bristol! How do cells translate mechanical forces into signals that shape an embryo? Explore the fascinating interplay between YAP, Wnt signalling and tissue mechanics in zebrafish development. Join us! www.swbio.ac.uk/programme/pr...
Steffen Scholpp
Steffen Scholpp
@scholpplab.bsky.social
I am a cell and developmental biologist at the Living Systems Institute (LSI) in Exeter. We work on spreading Wnt signals and characterising cytonemes in zebrafish embryos, human neurons, and cancer using high-res imaging and mathematical modelling.
2.6K followers2.7K following165 posts
Great two days at our Wnt SFB 1324 meeting @heidelberg ! 🧬 Fantastic science, fresh ideas, new tools & lots of exciting collaborations. Great to have Lizzy, Gemma & Jess presenting their work and getting inspired. Now back @lsiexeter.bsky.social to try it all out! 🔬🐟 #Wnt #Cytonemes
How does a Wnt cytoneme contact become a productive signalling site? Emma Cooper and colleagues find focal Ca²⁺ transients at cytoneme contacts and link Ca²⁺ availability to contact stability and Wnt/β-catenin signalling. www.biorxiv.org/content/10.6... #Wnt #Cytonemes #CellBiology
A fantastic start to our first @wellcometrust.bsky.social Cytoneme Network Workshop @lsiexeter.bsky.social, bringing together our Exeter and Manchester teams. Excited to uncover the unifying principles of contact-mediated signalling of Wnt, Notch, & Dpp in Drosophila, fish & mice. Cytonemes rock!
Steffen Scholpp reposted
#DBfeature A tribute to Gail R Martin, mouse geneticist and mentor extraordinaire (April 12, 1944 - Feb 9, 2026) By Alexandra Joyner doi.org/10.1016/j.ydbio.2026.05.007
Fantastic presentations of PhD students, postdocs, ECRs, and PIs from all the zebrafish groups in Exeter at #EZM2026 - well done everyone! Exeter is becoming a central hub for research using zebrafish as a model organism in the UK and Europe. #LSIZebrafsihHub @lsiexeter.bsky.social @exeter.ac.uk
Exeter is making waves at #EZM2026! Fantastic to see so many brilliant Exeter posters from development & disease to imaging&gene editing; great science & great people. From the West Country to Europe: Exeter is becoming a real zebrafish hotspot. Come say hi! @exeter.ac.uk @lsiexeter.bsky.social
No better way to head to #EZM2026 than with a freshly published success! Our eLife paper is now out: elifesciences.org/articles/107.... We show optimised prime editing in zebrafish for precise DNA substitutions and insertions. Huge thanks to the fantastic team #Zebrafish #GenomeEditing #eLife
The LSI Zebrafish Hub is very excited to welcome Prof Alex Schier - @schierlab.bsky.social - from the @biozentrum.unibas.ch for our Joint LSI/Biosciences Distinguished Seminar @lsiexeter.bsky.social tomorrow! Please come along & join us! #zebrafish #developmentalbiology @zebrafishrock.bsky.social
After months of experiments, failed injections, unexpected results, and those rare moments when everything suddenly works - our manuscript is finally submitted. Read our newest story about a journey of tiny vesicles carrying big biological messages, now in bioRxiv. www.biorxiv.org/content/10.6...
It was a pleasure to showcase our most recent data on cytonemes to the cell biology community in Bristol, including a long discussion about morphogen distribution mechanisms. Zebrafish cell biology rocks!
Excited to welcome @scholpplab.bsky.social from University of Exeter to balmy Bristol for a masterclass on all things WNT & cytonemes! It was a delightful talk featuring #zebrafish 🤩🐟 You can learn more about his lab's interests from their many reviews on cytonemes & intercellular communication ⬇️
Steffen Scholpp reposted
PL retweet. Developmental Biology Course (Quintay). More information: biodesarrollo.unab.cl
Wonderful PhD Day @lsiexeter.bsky.social today - full of great science, interdisciplinary projects, lively discussions and lots of laughter. Huge congratulations to our PhD students Jess Bansey and Lizzy Sears for winning Best Talk & Best Flash Talk Award. Very proud of you both! 👏 #PhDLife #ECRs
Very happy to share that I have joined the Heidelberg CRC/SFB 1324 “Mechanisms and Functions of Wnt Signalling” as a DFG Mercator Fellow. Looking forward to linking our work @lsiexeter.bsky.social with @cosheidelberg.bsky.social. Wonderful to hear Gemma's excellent presentation on cytonemes.
Steffen Scholpp reposted
Steffen Scholpp reposted
Important changes in the UKRI funding landscape. Thanks, Matt, for the update.
I watched much of Ian Chapman's (Head of @ukri.org) appearance this morning at @ukparliament.parliament.uk Science, Innovation and Technology Committee.. A few points and new information that bioscientists may find interesting... A 🧵
We are delighted to launch the Centre for Cellular Life, a new partnership between the @lsiexeter.bsky.social and SKLMB, Tsinghua University. Interdisciplinary science will drive collaborative research, researcher mobility and doctoral training to tackle how cells function in health and disease.
Great to see our collaboration between @tsinghuauniversity.bsky.social and the @lsiexeter.bsky.social taking shape after a fantastic visit to Beijing. We have established a strong foundation for joint research projects starting in 2026. Thanks to Li Yu and Fan Zhou for the excellent organisation.
Steffen Scholpp reposted
Looking for a PhD? 3 days left to apply for a fully funded China Scholarship Council & University of Exeter studentship! Join the Living Systems Institute—where Maths, Physics, Bio and Biomed meet—and carry out cutting-edge interdisciplinary research. tinyurl.com/y3ufdnxf @exeter.ac.uk
Steffen Scholpp reposted
Last chance to apply for one of the LSI PhD projects intake Sept 2026! Deadline tomorrow, 26.11.2025, noon. www.exeter.ac.uk/research/ins... @exeter.ac.uk @lsiexeter.bsky.social
Steffen Scholpp reposted
We’ve got a couple of PhD projects open. Including one with the lovely @adamgrieve.bsky.social and @scholpplab.bsky.social on Rhbdl proteins in #zebrafish which is open to UK and international students tinyurl.com/fishprotease
Thrilled to share that we have been awarded a Wellcome DA to explore cytoneme-based cell communication in development! A fantastic collaboration with Kyle @kylewedgwood.bsky.social at @lsiexeter.bsky.social, and Hilary Ashe & Cerys Manning at Manchester - exciting times ahead! tinyurl.com/2ytm6y2w
🚨 Exciting opportunity for 🇨🇳 students! Apply for a PhD scholarship via CSC to join my lab @UniofExeter studying cytoneme-mediated cell communication 🧫🐟 All projects are in collaboration with top Chinese universities: Tsinghua, Zhejiang & Kunming 🌏 📅 Deadline: 1 Dec 2025 携手探索细胞交流的奥秘,让科学没有距离!加油!💪🇨🇳✨
Fully Funded PhD Opportunity! Join the LSI @exeter.ac.uk - where Maths, Physics, Bio & Biomed unite under one roof. Funded by the China Scholarship Council & University of Exeter, this is your chance to do cutting-edge interdisciplinary research in a vibrant PhD community. tinyurl.com/y3ufdnxf
Steffen Scholpp reposted
As a science communicator who built my professional career out of understanding "Science Twitter": I'm confident Bluesky will be the scientific community's social media home for a while Tell your friends at #ASHG25 to get over here, whether they're on X or not!
WOW! Our survey of scientists who stopped using Twitter and started using Bluesky is now the #1 most-shared on social media article in the history of the journal Integrative and Comparative Biology! Thanks for reading it, everyone! @sicbjournals.bsky.social doi.org/10.1093/icb/... 🧪
Deadline approaching – 15 Oct! A brilliant PhD opportunity for all keen zebrafish enthusiasts, gene jockey and microscopy aficionados 🐟🧬🔬 If you find joy in embryos, lasers, and watching cells do clever things — this is your moment.
Want to help prevent aggressive NF1 cancers using cutting-edge models? The GW4 BioMed2 MRC DTP is offering a fully funded 4-year PhD @lsiexeter.bsky.social @exeter.ac.uk to develop a humanised zebrafish model for NF1 resilience. Apply by 20 Oct 2025 www.exeter.ac.uk/study/fundin... #PhD #biomed
Such sad news. An amazing scientist, an amazing person, and a wonderful and inspiring lecturer. Will be greatly missed. www.cam.ac.uk/research/new...
Back from the London Zebrafish Research Network — a truly inspiring afternoon. Many thanks to @cvagenapantoula.bsky.social, @kkalyviotis.bsky.social and Eleni for putting together such an interactive programme, full of excellent talks - Tim 👏 - and great discussions. Zebbie research at its best!
Want to help prevent aggressive NF1 cancers using cutting-edge models? The GW4 BioMed2 MRC DTP is offering a fully funded 4-year PhD @lsiexeter.bsky.social @exeter.ac.uk to develop a humanised zebrafish model for NF1 resilience. Apply by 20 Oct 2025 www.exeter.ac.uk/study/fundin... #PhD #biomed
Day 1 of #UKZF2025 is here! 🎉🐟 The conference kicks off in Exeter & Exmouth — packed with science, networking, and community. Let’s dive in! 🚀 @izfs.bsky.social @zebrafishrock.bsky.social @lsiexeter.bsky.social @zebrafishhusbandry.bsky.social
Interested in zebrafish as a disease model for NF1? We are seeking a motivated PhD student to join our team and become an expert in high-resolution imaging/precise genome editing in collab with AZ. gw4biomed.ac.uk/establishing... @lsiexeter.bsky.social @zebrafishrock.bsky.social @izfs.bsky.social
Why do some people with #NF1 develop aggressive nerve tumours while others don’t? 🧬🐟 Join us to explore genetic resilience in zebrafish, uncover protective pathways & discover new strategies to prevent cancer. gw4biomed.ac.uk/establishing... @lsiexeter.bsky.social
Huge congratulations to our brilliant graduates: one newly minted PhD, a sharp MSc, and two stellar BScs! You all looked majestic in your gowns — a well-earned symbol of your hard work, late nights, and scientific curiosity. Serious achievements, bright futures. @lsiexeter.bsky.social @exeter.ac.uk
Power presentation of Bertram about the beauty of cryo EM at the #LSIOpenDay. @lsiexeter.bsky.social
Time is running out to present your latest #Zebrafish research at ZFUK25 tinyurl.com/mw7r3nbn in Exeter. This is your chance to share your work, connect with the community, and contribute to cutting-edge discussions. The deadline for abstract submission is rapidly approaching: 30th June 2025!
Thrilled to announce a seminar featuring Prof. Hilary Ashe, a leading Cell & Developmental Biologist from @UoM_BioSci! Discover her lab's latest findings on spatiotemporal gene expression & cell communication in #Drosophila @lsiexeter.bsky.social
Steffen Scholpp reposted
Carer's Awards, funded by the Genetics Society, are available to support 3 participants of the First UK Zebrafish Meeting with caring responsibilities. @gensocuk.bsky.social More info at exeter.ac.uk/ukzfmeeting
Don't miss the First UK Zebrafish Meeting @lsiexeter.bsky.social in Exeter, sponsored by @brukercorporation.bsky.social @brukerspatial.bsky.social al.bsky.social! 🐠 Join us Sept 10 - 12. Early bird registration closes soon! Secure your spot. www.exeter.ac.uk/research/ins...