Mac Shine

📜 FINALLY OUT! 📜 In @imagingneurosci.bsky.social (@mitpress.bsky.social), myself, Lionel Barnett, @anilseth.bsky.social, Olivia carter, and @thomasandrillon.bsky.social, advance approaches of #multiscale #emergence and it's application to EEG across #conscious #states. Buckle up 👇 1/n

If an action results in error, each neuron requires an individualized teaching signal that guides change in its output. This is the credit assignment problem of learning. Are there neurons in the brain that can compute such a sophisticated teaching signal? Yes. www.biorxiv.org/content/10.6...

@macshine.bsky.social talks with @satra.bsky.social about the #OHBM2026 Abstract Atlas—a community-built tool that places every 2026 abstract inside the broader neuroscience landscape. Where does your work sit in the field? #neuroskyence www.thetransmitter.org/open-source-...

🎉 Registration is now OPEN for the 2026 OHBM Australian Chapter Annual Meeting! 🇦🇺🧠🇦🇺 Get your ticket now! 🎟️🎟️🎟️ Registration: events.humanitix.com/ohbm-austral... 📝 Submit your abstract: docs.google.com/forms/d/e/1F... 🏆 Nominate a colleague (or yourself) for an award: ohbm-aus.github.io/awards/

@macshine.bsky.social talks with @melcooperphd.bsky.social about her new work showing that astrocytes—long dismissed as the brain’s housekeepers—are wired together in precise, long-range networks that remodel in response to experience. #neuroskyence www.thetransmitter.org/astrocytes/t...

@macshine.bsky.social talks with Mario Senden about his new project using AI-driven bibliometrics to map the structural organization of neuroscience across 25 years. The field it reveals is at once thriving and theoretically adrift. #neuroskyence www.thetransmitter.org/methods/what...

fMRI connectivity is dominated by recurring high-amplitude BOLD events (CAPs, QPPs) But what originates these events? Many think neuromodulation is the culprit. Our new work offers a simpler take: cortico-cortical dynamics alone can generate CAP-like events! doi.org/10.1371/journal.pcbi.1013995 🧵1/n

I recently had the pleasure of chatting with @macshine.bsky.social as part of the OHBM Award Winner interview series; thanks for a great conversation! 🙏 Catch the interview here 👇

𝗔 𝗡𝗘𝗨𝗥𝗢𝗘𝗖𝗢𝗟𝗢𝗚𝗜𝗖𝗔𝗟 𝗣𝗘𝗥𝗦𝗣𝗘𝗖𝗧𝗜𝗩𝗘 𝗢𝗡 𝗧𝗛𝗘 𝗣𝗥𝗘𝗙𝗥𝗢𝗡𝗧𝗔𝗟 𝗖𝗢𝗥𝗧𝗘𝗫 By Mars and Passingham "Understanding anthropoid foraging challenges may thus contribute to our understanding of human cognition" Going to the top of the reading list! doi.org/10.1016/j.ne... #neuroskyence

*New preprint from the lab* – “Granularity of thalamic head direction cells” doi.org/10.1101/2025... 🧠📈 🧪 1/11

What changes and what stays the same as you scale from single neurons up to local populations of neurons up to whole brains? Michael and Mac @macshine.bsky.social on the systems approach to study brains across scales. braininspired.co/podcast/220/

Excited to share my latest work with @jonathanamichaels.bsky.social @diedrichsenjorn.bsky.social & @andpru.bsky.social! We asked: How does the motor cortex account for arm posture when generating movement? Paper 👉 www.biorxiv.org/content/10.1... 1/10

Adaptive learning is coordinated across behaviour, time and neurobiology (from synapses and dendrites, to astrocytes and the systems level). If you’ve ever wondered how noradrenaline helps shape these multiscale learning processes, you might like this: www.cell.com/trends/cogni...

Theoretical neuroscience has room to grow — a Comment article by Ann Kennedy @antihebbiann.bsky.social #neuroscience #neuroskyence www.nature.com/articles/s41...

🚨Pre-print alert🚨 We stimulated serotonin with optogenetics while doing large-scale Neuropixel recordings across the mouse brain. We found strong widespread modulation of neural activity, but no effect on the choices of the mouse 🐭 How is this possible? Strap in! (1/9) 👇🧵 doi.org/10.1101/2025...

🚨 California and Hawaii under tsunami watch after 8.7M quake in Eastern Russia.

The point is, the monkeys making the loudest noise have the smallest balls. pubmed.ncbi.nlm.nih.gov/26592343/

An exciting collaboration is underway. @thetransmitter.bsky.social is partnering with @neuromatch.bsky.social to serve the computational neuroscience community and help connect neuroscientists across all career stages. www.thetransmitter.org/neuromatch-p... #neuroskyence

“the kindest person in the room is often the smartest.” JB Pritzker is a mensch.

Prefrontal axons going to lots of places! doi.org/10.1016/j.ce... #neuroskyence

Pairs well with www.nature.com/articles/s41... “Our results indicate that individual V1 neurons do not signal how the actual visual input deviates from the animal’s predictions, as postulated within the predictive coding framework” Thrilling to see a major theory get tested!

Really proud to start the year by sharing our new review in @endosocjournals.bsky.social on the roles of GLP-1 in eating and obesity treatment, led by superstar postdoc @laurenjonesucl.bsky.social! academic.oup.com/endo/article... 🧪🧠📈 #neuroscience #neuroskyence #GLP-1 #obesity #wegovy #ozempic

I honestly think we should have a screening system for who gets to have money and influence based on asking "what was Star Wars about?" and "who were the good guys?"

Molecular and functional diversity of the autonomic nervous system — a Review by Tongtong Wang, Avedis Tufenkjian, Olujimi A. Ajijola & Yuki Oka #neuroscience #neuroskyence www.nature.com/articles/s41...

Exciting new preprint from the lab: “Adopting a human developmental visual diet yields robust, shape-based AI vision”. A most wonderful case where brain inspiration massively improved AI solutions. Work with @zejinlu.bsky.social @sushrutthorat.bsky.social and Radek Cichy arxiv.org/abs/2507.03168

🚨 New paper in Journal of Vision! We show that scene affordances—what you can do in a space—shape how we perceive and categorize scenes. This shapes your similarity preferences, predicts your categorization false alarms, and even alters neural representations. 🧵👇 🔗 doi.org/10.1167/jov.... (1/7)

Attractors are usually not mechanisms - new blog post: open.substack.com/pub/kording/...

How does the human brain coordinate hierarchical cortical development? Our work in Nature Neuroscience identifies a role for thalamocortical structural connectivity in the expression of hierarchical periods of cortical plasticity & environmental receptivity in youth 🧵 www.nature.com/articles/s41...

Short new piece on aphantasia just out in TiCS: www.sciencedirect.com/science/arti... Key idea: aphantasia often involves a lack of *visual-object* imagery (explaining subjective reports & objective correlates) but selectively spared *spatial* imagery (explaining preserved task performance).

ICYMI: “For fMRI to meaningfully contribute to progress in neuroscience, we need to develop research programs that link phenomena across levels,” writes Avram Holmes @avramholmes.bsky.social. www.thetransmitter.org/future-of-fm...

Another great article from @thetransmitter.bsky.social and Laura Lewis, who has been working painstakingly over the last few years to help ramp up the spatiotemporal resolution of fMRI so that we can really start to dig into whole-brain signals in vivo.

ICYMI: Recent technological advances in functional MRI provide a range of new information about brain physiology. Collaboration between engineers and neuroscientists will help maximize these gains, writes Laura Lewis. www.thetransmitter.org/human-neurot...

Paper is here: arxiv.org/abs/2506.19800 Code is here: github.com/DynamicsAndN... If you're interested and at #OHBM2025 come watch Rishi present his work in the "Modeling and Analysis - Connectivity" workshop on Saturday in the Great Hall; and check out his poster #1440 (on Friday & Saturday)

New preprint! Why are long-range connectomic interactions in the cortex dominant in shaping dynamics in some experiments but apparently negligible in others? We (w/ R Maran, @elimuller.bsky.social) address this question by studying a new hybrid model of cortical dynamics. arxiv.org/abs/2506.19800

The Open Science Room has been an exciting space at the OHBM Meeting for many years, but its future is threatened. Please sign this petition to signal your support for preserving a dedicated space for the OSR at future meetings. ohbm.github.io/osr2025/peti...

Useful #OHBM2024 deep link - Table listing all posters with stand-by times & categories gmpartners365-my.sharepoint.com/:x:/g/person...

Fantastic article from one of the leaders of the burgeoning field or layer-resolved functional MRI. A pleasure to read!

ICYMI: In this essay for our Future of fMRI series, Laurentius Huber @layerfmri.bsky.social explains how new advances in functional MRI could help to connect cells and brain areas at the mesoscopic scale. #neuroskyence #OHBM2025 www.thetransmitter.org/future-of-fm...

The diversity of methods we use to probe the brain (epistemologies) naturally leads to clashes in our theories of how the brain works (ontologies). So how do we reconcile this divide and grow into a more unified neuroscience? Here is our take: apertureneuro.org/article/1388...

🧠 The State of the Brain Special Issue features insights from last year’s keynotes, award winners & committee leaders. 🔗 Explore major findings & themes from 2024: apertureneuro.org/issue/12560 @arokem.org @alexfornito.bsky.social @macshine.bsky.social @vcalhoun.bsky.social @misicbata.bsky.social

New preprint modelling suppression depth in binocular rivalry and continuous flash suppression with Hugh Wilson, @macshine.bsky.social, & David Alais

COS Statement on “Restoring Gold Standard Science” Executive Order www.cos.io/about/news/c...