Ashley Tyrer

Ashley Tyrer

@ashleytyrer.bsky.social

Ass. Prof with @the-ecg.bsky.social ✨ Noradrenaline, decision-making, and brain-body interactions, with a sprinkle of Dynamic Causal Modelling and Active Inference 🧠 Chair-Elect, OHBMComCom 🤓 📰 https://ashleytyrer.github.io/

693 followers287 following92 posts

Ashley Tyrer reposted

Your monthly reminder that if you're using ChatGPT to do your science, you're failing your colleagues, community, and all of us. Here, ChatGPT makes up data and presents it as the real thing — then apologizes when confronted.

Ashley Tyrer reposted

We, the Natural Decision Making Group and the Embodied Decision Making Group, are joining forces to establish the CMC Unit, a joint research unit to uncover computational, biological, and ecological principles underlying adaptive decision-making. You can read more about us here: cmc-unit.org

Ashley Tyrer reposted

Tomorrow 4th seminar of The Interoception Circle: 🫀 Marta Gerosa Cardiorespiratory and Vascular Dynamics in Voluntary Action, Sense of Agency and Active Sampling 📅 7 Oct, 12:00 CEST 💻 Online, everyone welcome here: teams.microsoft.com/meet/3768311... More info: ace2lab.com/2581-2/

ace2lab.comACE2LABHome page | Lab & People | Publications | Outreach | Join Lab | Interoception Circle This monthly series provides a open forum for current research on how bodily signals shape perception, cogni…

Ashley Tyrer reposted

Some months ago, I wrote a skeptical reply to a commentary on bots in online studies in PNAS, arguing that no evidence yet exists for such bots. Together with the authors of the original commentary, we now show that bots can pass (almost?) all online cognitive studies with human-like performance 1/n

Christoph Strauch@cstrauch.bsky.social

How much of a risk are LLM-generated bots for online behavioral experiments? We present results of an entirely natural language prompt-generated agent, capable of absolving any of the 26 experiments we tested it on. Most tasks are passed with data that can pass as human osf.io/preprints/ps... (1/)

Ashley Tyrer reposted

2023: 8,039 proposals 2024: 10,360 proposals 2025: 17,066 proposals 2026: 21,627 proposals Something's gotta give

Iva Vukušić@vukusiciva.bsky.social

This ridiculous number of applications is, in my view, the result of 2 nightmare developments happening concurrently 1.the precariousness of the job market for young PhD graduates which then fuels further: 2.the AI tools enabling overproduction of proposals. #Research #ERC #ResearchFunding #Academia

Ashley Tyrer reposted

Ashley Tyrer reposted

Ashley Tyrer reposted

Ashley Tyrer reposted

Ashley Tyrer reposted

Our new paper in @natureportfolio.nature.com. Psychedelics don’t simply disorder the brain. We found hidden, context-sensitive organisation beneath the apparent chaos -- strongest in people reporting more positive, profound experiences and a reduced sense of separation from the world. 🧵👇

Ashley Tyrer reposted

How are you deciding to decide? A much overlooked part of decision making is determining when one should stop gathering information. In our new fMRI preprint, we show that distinct brain networks track decision-critical variables, congregation in dmPFC. For more details, see our thread 👇🏼

kenzakdr.bsky.social@kenzakdr.bsky.social

1/6 New preprint! 🧵 How do we decide to decide? With @aleyamarzuki.bsky.social we showed that the interplay between urgency, evidence accumulation, and prediction errors converges in the dmPFC, into one signal: keep gathering information, or stop and commit to a choice. doi.org/10.64898/202...

Ashley Tyrer reposted

New publication in Translational Psychiatry by Nora Czekalla et al. from the Social Neuroscience Lab in Lübeck 💫 www.nature.com/articles/s41... We all know the experience: Something goes better than expected, someone gives us positive feedback - and yet somehow, we don’t really believe it. TL;DR👇

nature.comAberrant insula activity to negative and reduced learning from positive feedback underlie maladaptive self-beliefs in depression - Translational PsychiatryTranslational Psychiatry - Aberrant insula activity to negative and reduced learning from positive feedback underlie maladaptive self-beliefs in depression

Ashley Tyrer reposted

Ashley Tyrer reposted

It’s election week! At this important moment I would like to address your entire planet with a message to the people of Earth. And I think I found the perfect place to do it.

Ashley Tyrer reposted

Ashley Tyrer reposted

Ashley Tyrer reposted

Check out our latest work! Multimodal brain imaging meets gamified computational psychiatry! Great work from Ashley and the team.

Ashley Tyrer@ashleytyrer.bsky.social

1/ I’m delighted to share our new paper, out now in @cpsyjournal.bsky.social with @tobiasuhauser.bsky.social and @micahgallen.com, correlating variations in cortical microstructures with individual differences in gamified exploration-exploitation behaviours! 🧵 doi.org/10.5334/cpsy...

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12/ Interestingly, our analyses did not identify correlations in canonical dopaminergic midbrain regions 🤔 This could result from our rigorous regression pipeline with correction for multiple comparisons, which may lead to reduced sensitivity to subtler effects from smaller regions. 💪

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10/ Key takeaways: Our findings suggest that individual differences in decision-making and exploration behaviours may have distinct microstructural foundations in the brain! 🔑

11/ Why does this matter? This research highlights potential for future work examining how cortical microstructures differ in individuals suffering from mental health conditions characterised by aberrant decision-making, such as ADHD or anxiety.

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8/ We found greater indices of cortical myelination in right superior frontal brain regions - previously linked to impulsivity - to be strongly associated with increased value-free random exploration in long horizon trials, i.e., trials in which exploration is beneficial!

9/ We also found negative correlations between markers of myeloarchitecture in the right postcentral gyrus & right superior parietal lobule, and value-free random exploration in short horizon trials - trials in which exploration is NOT beneficial!

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6/ Participants also showed greater novelty exploration and greater uncertainty about a bandit’s mean value (prior variance), in long versus short horizon trials, further demonstrating that long horizon trials engendered robust value-free exploratory behaviours.

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4/ We specifically focused on ‘value-free random exploration’: an exploration strategy which disregards all existing knowledge of the decision space, thus considering all available choices to be equally likely.

2/ Throughout life, we face decision-making dilemmas such as the exploration-exploitation trade-off. One must choose either the highest-value option (exploitation), or an alternative, lesser-known option which may yield yet greater rewards but at the risk of disappointment (exploration).

3/ To investigate this behaviour, we combined the gamified multi-armed bandit task, Maggie’s Farm, with computational modelling to extract subject-specific parameters of exploration behaviours from 122 healthy human volunteers. 🧠

Ashley Tyrer reposted

Fascinating and important. Including the provocative finding “What we believe about our bodily sensing may have little to do with how we actually sense it.” A place where subject report diverges (read the thread). Congrats to this team!!

Leah Banellis@leahbanellis.bsky.social

Sensing your body (‘Interoception’) is everywhere in theories of mental health. But when we tested how well hundreds of people sensed their heart and lungs, the link to symptoms was almost nowhere to be found. 💣 🚨New @natmentalhealth.nature.com paper 🚨🎉 asks why 🧵 www.nature.com/articles/s44...

Ashley Tyrer reposted

Ashley Tyrer reposted

After an incredible OHBM 2026, we can't wait to welcome the global neuroimaging community to Toronto for #OHBM2027! 🍁 📅 June 26–30, 2027 📍 Metro Toronto Convention Centre Save the date and join us for another year of discovery, collaboration, and innovation.