Matt Clancy

Matt Clancy

@mattsclancy.bsky.social

Runs Open Philanthropy’s Innovation Policy program. Creator of newthingsunderthesun.com, a living literature review about innovation. Website: mattsclancy.com.

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What’s the return on government support for R&D? To try to get a credible answer, Open Philanthropy and the Sloan Foundation are committing up to $1 million to trying something new: we call it a Pop-Up Journal.

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Lastly, I think the most original illustration is for “Advance Market Commitments,” where we imagine building a town to provide a rationale for a train line to enter the region.

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For “R&D Subsidies”, we wanted something that captured the way a subsidy is usually undirected, and supports R&D effort at lots of different kinds of orgs, like the wind pushing forward all boats.

For “Intramural science” (think national labs or my old employer, the USDA Economic Research Service) we’ve got scholarly work happening at a remove from the rest of society - in this case on a mountain top.

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Apply by January 9, 2026 (this Friday!) for consideration. Be sure to share with the less online students you know. We welcome applications from anyone who has completed the equivalent of a first year economics PhD. ifp.org/economics-of...

ifp.orgReady to apply? More details below. | Institute for ProgressOur target audience is current or recent students who have completed at least one year of a PhD program in economics or related fields. Acceptance, however,
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6. Science and the Returns to R&D, Matt Clancy (me) 7. AI and Innovation, Kevin Bryan 8. Innovation Policy, John Van Reenen 9. Immigration and Innovation, Michael Clemens 10. Regulation, Heidi Williams

11. Competition and Innovation, Mitsuru Igami 12. Patent Policy, Janet Freilich 13. Advice on Research and Careers, panel of Caleb Watney, Heidi Williams, Matt Clancy

The course runs from early February through late March. Each week is an interactive zoom lecture from a different expert in the relevant field, plus a meeting with a small group of other students to discuss assigned readings.

Schedule: 1. Introduction to the economics of Idea, Ben Jones 2. Idea-based models of economic growth, Chad Jones 3. The supply of Innovators, Ina Ganguli 4. Open Science as an Economic Institution, Pierre Azoulay 5. The Direction of Science, Kyle Myers

Matt Clancy reposted

Excellent retrospective approach to a timely prospective question.

Matt Clancy@mattsclancy.bsky.social

New research by Pierre Azoulay, Danielle Li, Bhaven Sampat and me. Earlier this year, the President’s budget proposed a 40% cut to the budget of the NIH. This motivated us to ask: what if the NIH had been 40% smaller?

New research by Pierre Azoulay, Danielle Li, Bhaven Sampat and me. Earlier this year, the President’s budget proposed a 40% cut to the budget of the NIH. This motivated us to ask: what if the NIH had been 40% smaller?

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We find that drugs that cite at-risk research are, on average, no less likely to get priority reviews at FDA and do not have worse implied valuations by the stock market. In short, we don’t have reason to believe drugs linked to at-risk research are worse.

New research by Pierre Azoulay, Danielle Li, Bhaven Sampat and me. Earlier this year, the President’s budget proposed a 40% cut to the budget of the NIH. This motivated us to ask: what if the NIH had been 40% smaller?

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Finally, it’s less common, but in some cases, drugs directly acknowledge support from specific NIH grants in their patents. Only 40 drugs acknowledge NIH grant support, but of that group, 14 (35%) acknowledge support from a grant that is at-risk.

Are drugs linked to at-risk research worse? We look at two proxies for drug value: whether a drug gets priority review at the FDA, and stock market reactions when a drug patent is announced. Yes, very imperfect, but we think still worth looking at.

New research by Pierre Azoulay, Danielle Li, Bhaven Sampat and me. Earlier this year, the President’s budget proposed a 40% cut to the budget of the NIH. This motivated us to ask: what if the NIH had been 40% smaller?

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This doesn’t mean 51% of drugs wouldn’t exist if the NIH had been 40% smaller. Various caveats cut in different ways (see discussion in the online appendix). But we take this as evidence that the benefits of at-risk NIH research are wide and diffuse.

We consider other ways to link drugs with at-risk grants. For example, we find that 12% of drugs have more than a quarter of their patent-to-paper citations going to at-risk research. See the paper for some examples of specific drugs.

New research by Pierre Azoulay, Danielle Li, Bhaven Sampat and me. Earlier this year, the President’s budget proposed a 40% cut to the budget of the NIH. This motivated us to ask: what if the NIH had been 40% smaller?

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Would anyone miss the research funded by these at-risk grants? To help assess that, we link these at-risk grants to drugs, focusing on all 557 FDA approvals for new molecular entities approved in the 21st century.

Most new drugs are protected by patents. We look at these patents to see if they cite research funded by at-risk grants. We find 51% of drugs have a patent that cites one or more articles funded by an at-risk grant.

New research by Pierre Azoulay, Danielle Li, Bhaven Sampat and me. Earlier this year, the President’s budget proposed a 40% cut to the budget of the NIH. This motivated us to ask: what if the NIH had been 40% smaller?

We have the real priority scores for all NIH grants made over 1980-2007. Since NIH mostly funds research by working down these priority scores until the budget runs out, we can identify the grants that would probably have been cut with a smaller budget.

Matt Clancy reposted

Deadline to apply to these positions is today! Big opportunity to accelerate growth and progress in housing, energy, clinical trials, and more.

Matt Clancy@mattsclancy.bsky.social

The Abundance and Growth Fund at Open Philanthropy is hiring! We’re looking for 2-4 people to help expand this new $120+ million program to accelerate economic growth and reduce the cost of living through strategic grantmaking and research. (1/4) www.openphilanthropy.org/research/ann...

Matt Clancy reposted

We’re interested in putting together a team with expertise across many different possible areas: housing policy, energy, infrastructure, state capacity, healthcare and clinical trials, economic dynamism, and more. (2/4)

Matt Clancy reposted

Este es el futuro.

Matt Clancy@mattsclancy.bsky.social

What’s the return on government support for R&D? To try to get a credible answer, Open Philanthropy and the Sloan Foundation are committing up to $1 million to trying something new: we call it a Pop-Up Journal.

Matt Clancy reposted

Enter the 1st pop‑up journal, true living R&D ROI lab for Zvi Griliches: revisiting his seminal question, catalyzing his legacy in real‑time policy, and promising impact no posthumous Econ Nobel (which he more than deserved!) ever could. Arguably the wisest academic publishing initiative in decades.

Matt Clancy@mattsclancy.bsky.social

What’s the return on government support for R&D? To try to get a credible answer, Open Philanthropy and the Sloan Foundation are committing up to $1 million to trying something new: we call it a Pop-Up Journal.

Matt Clancy reposted

Such a clever idea. You could imagine its application to all sorts of wicked problems…

Matt Clancy@mattsclancy.bsky.social

What’s the return on government support for R&D? To try to get a credible answer, Open Philanthropy and the Sloan Foundation are committing up to $1 million to trying something new: we call it a Pop-Up Journal.

Matt Clancy reposted

This is a really cool kind of initiative: a pop-up journal on the returns to public R&D: popupjournal.com. Pop-up journals to coordinate research on questions that matter!

popupjournal.comThe Pop-Up Journal Initiative
Matt Clancy@mattsclancy.bsky.social

Finally: we think Pop-Up Journals will be a useful way to help the academic community coordinate on answering big questions of all kinds and communicate those answers to the policy world. This Pop-Up Journal is only the first we plan to support.

Matt Clancy reposted

Interesting initiative!

Matt Clancy@mattsclancy.bsky.social

Finally: we think Pop-Up Journals will be a useful way to help the academic community coordinate on answering big questions of all kinds and communicate those answers to the policy world. This Pop-Up Journal is only the first we plan to support.

Matt Clancy reposted

Love this - need more innovation in academic publishing

Matt Clancy@mattsclancy.bsky.social

What’s the return on government support for R&D? To try to get a credible answer, Open Philanthropy and the Sloan Foundation are committing up to $1 million to trying something new: we call it a Pop-Up Journal.

Matt Clancy reposted

Very excited to join with Open Philanthropy on an all-out sprint to answer some of the thorniest practical questions in economics. First question: What return do we get when we invest in R&D?

Matt Clancy@mattsclancy.bsky.social

What’s the return on government support for R&D? To try to get a credible answer, Open Philanthropy and the Sloan Foundation are committing up to $1 million to trying something new: we call it a Pop-Up Journal.

Matt Clancy reposted

interesting idea. we need more innovation in the research publication/curation space.

Matt Clancy@mattsclancy.bsky.social

What’s the return on government support for R&D? To try to get a credible answer, Open Philanthropy and the Sloan Foundation are committing up to $1 million to trying something new: we call it a Pop-Up Journal.

Matt Clancy reposted

Very cool!

Matt Clancy@mattsclancy.bsky.social

What’s the return on government support for R&D? To try to get a credible answer, Open Philanthropy and the Sloan Foundation are committing up to $1 million to trying something new: we call it a Pop-Up Journal.