Tanner Richie

Tanner Richie

@microberich.bsky.social

Postdoc UVA SOM Pediatrics | 🧫 PhD Kansas State University | Alumni of NCSU 🐺 | Microbes influencing gut outcomes and the importance of balance | Gut Microbiota | ‘Omics | Avid pianist 🎹 and occasional cupcake baker

642 followers437 following26 posts

Tanner Richie
@microberich.bsky.social

Final PhD chapter is PhDone!! ✨ Thrilled to see this out and a massive thank you to my incredible co-authors and mentor @sonnytmlee.bsky.social! Check it out below! #microbiome #microbialmetabolites #research #GutHealth #IBD

Microbiome@microbiomej.bsky.social

In #Microbiome Microbially derived glutathione from Eubacterium rectale alleviates oxidative stress and promotes intestinal epithelial recovery🦠 Read more➡️ doi.org/rjc8 #Microbes

Tanner Richie
@microberich.bsky.social

A very difficult Friday for early career scientists.

Audrey Drotos, PhD 🧠 🔬@audreydrotos.bsky.social

Heartbroken to hear that the @hhmi.org Hanna Grey fellowship competition is being cancelled this year. I poured so much work and creativity into this app and am very grateful for everyone who helped me revise. It is such a difficult time to be a young scientist.

Tanner Richie reposted

Manuel Kleiner
@manuelkleiner.bsky.social

When you do #Metagenomics and #Metaproteomics with mice fed a standard diet with Casein make sure to account for the large amount of dead L. lactis that comes with the diet analyticalsciencejournals.onlinelibrary.wiley.com/doi/10.1002/...

analyticalsciencejournals.onlinelibrary.wiley.comLarge Quantities of Bacterial DNA and Protein in Common Dietary Protein Source Used in Microbiome StudiesDiet has been shown to greatly impact the intestinal microbiota. To understand the role of individual dietary components, defined diets with purified components are frequently used in diet-microbiota...
Tanner Richie
@microberich.bsky.social

The best of multi-omics on plant microbe interactions! Very exciting work!

Anna Kazarina@akazarina.bsky.social

The 2nd project of my PhD work is now live! We showed strong associations of plant-derived metabolite trimethyllysine and rhizobiome functions, on mechanisms of rhizosphere recruitment and the microbial capacity to enhance host’s drought stress resilience. @sonnytmlee.bsky.social shorturl.at/mivJs

shorturl.atInteraction of plant-derived metabolites and rhizobiome functions enhances drought stress toleranceBackground : Plants evolved alongside microbes, enabling plants to better cope with abiotic and biotic stresses. The interactions between plant roots and local soil microbes are critical for environme...
Tanner Richie
@microberich.bsky.social

What an amazing celebration! Thank you all, I will miss the Lee lab and the friends made along the way.

Sonny T M Lee@sonnytmlee.bsky.social

The lab dressed up, had great food and then drinks at the Speakeasy, celebrating @microberich.bsky.social leaving the lab and heading to UVA for her postdoc. World, look out for her future endeavor!

Tanner Richie
@microberich.bsky.social

Beyond thrilled to see my 2nd Chapter hot off the preprint presses! This project examines Eubacterium rectale for alleviation of gut epithelium ROS damage through biosynthesis of the antioxidant glutathione. Check it out! #microbiomesky #IBD #microsky 🧪🧫

biorxiv.orgEubacterium rectale detoxification mechanism increases resilience of the gut environmentbioRxiv - the preprint server for biology, operated by Cold Spring Harbor Laboratory, a research and educational institution
Tanner Richie
@microberich.bsky.social

So excited that my thesis first chapter is live in ASM's #mSystems journals.asm.org/doi/10.1128/... We use a bunch of techniques to show that gut microbial populations may be “stealing” valuable amino acids from the mice host, resulting in persistent gut inflammation! #PhDSky #MicroSky 🧪🦠🧫🧬

journals.asm.orgLimitation of amino acid availability by bacterial populations during enhanced colitis in IBD mouse ...Inflammatory bowel disease is associated with an increase in Enterobacteriaceae and Enterococcus species; however, the specific mechanisms are unclear. Previous research has reported the associations ...
Tanner Richie
@microberich.bsky.social

So excited that my thesis first chapter is live in ASM's #mSystems journals.asm.org/doi/10.1128/... We use a bunch of techniques to show that gut microbial populations may be “stealing” valuable amino acids from the mice host, resulting in persistent gut inflammation! #PhDSky #MicroSky 🧪🦠🧫🧬

journals.asm.orgLimitation of amino acid availability by bacterial populations during enhanced colitis in IBD mouse ...Inflammatory bowel disease is associated with an increase in Enterobacteriaceae and Enterococcus species; however, the specific mechanisms are unclear. Previous research has reported the associations ...
Tanner Richie
@microberich.bsky.social

Next, to prove that, we isolated and cultured these MAGs and showed that they can indeed use cysteine. We also showed that MAGs/isolates from dysbiotic mice can used cysteine more effectively for growth than MAGs/isolates from healthy mice.

Tanner Richie
@microberich.bsky.social

So excited that my thesis first chapter is live in ASM's #mSystems journals.asm.org/doi/10.1128/... We use a bunch of techniques to show that gut microbial populations may be “stealing” valuable amino acids from the mice host, resulting in persistent gut inflammation! #PhDSky #MicroSky 🧪🦠🧫🧬

journals.asm.orgLimitation of amino acid availability by bacterial populations during enhanced colitis in IBD mouse ...Inflammatory bowel disease is associated with an increase in Enterobacteriaceae and Enterococcus species; however, the specific mechanisms are unclear. Previous research has reported the associations ...
Tanner Richie
@microberich.bsky.social

I performed network analyses showing the high association of host cysteine metabolizing genes and MAGs of interest. This drives our thought that the MAGs may be “stealing” valuable cysteine from the host.

Tanner Richie
@microberich.bsky.social

So excited that my thesis first chapter is live in ASM's #mSystems journals.asm.org/doi/10.1128/... We use a bunch of techniques to show that gut microbial populations may be “stealing” valuable amino acids from the mice host, resulting in persistent gut inflammation! #PhDSky #MicroSky 🧪🦠🧫🧬

journals.asm.orgLimitation of amino acid availability by bacterial populations during enhanced colitis in IBD mouse ...Inflammatory bowel disease is associated with an increase in Enterobacteriaceae and Enterococcus species; however, the specific mechanisms are unclear. Previous research has reported the associations ...
Tanner Richie
@microberich.bsky.social

We found that IL-10KO vertical transmitted dysbiotic mice are scavenging for cysteine that may aid in gut immune homeostasis. On the other hand, we assembled MAGs, and found several MAGs that are highly detected in dysbiotic mice have genomic capability of metabolizing cysteine.

Tanner Richie
@microberich.bsky.social

Excited to see this article now online! Bringing attention to the need of revolutionizing cancer treatments and how our gut microbes may play a role in personalized care! 🦠🧪🧫https://www.nasw.org/article/nasw-science-writers-education-committee-2023-perlman-program-tanner-richie #SciComm #PhDSky

nasw.orgPrecision Prescribing for Colon Cancer Based on Gut MicrobesThis student story was published as part of the 2023 NASW Perlman Virtual Mentoring Program organized by the NASW Education Committee, providing science journalism practice and experience for undergra...
Tanner Richie
@microberich.bsky.social

Hi all! #HiSciSky #AcademicSky Happy to join the Blue side! Current PhD candidate looking into microbial roles and mechanisms in gut inflammation and homeostasis! Using #omics and molecular techniques! Also keen on #scicomm

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