Marco Podobnik

Our @natrevgenet.nature.com article out now. This is a hymn to danionin fishes, with sections on phylogeny, reproduction, immunity, morphology, regeneration and behaviour. rdcu.be/CntbxvfZsUba

Our review on the interplay between metabolism and tissue mechanics is now published in @dev-journal.bsky.social Development!

A new preprint from our lab: www.medrxiv.org/content/10.6... A rapid zebrafish embryo–based method developed by Shantanu for classifying nanos gene variants as potentially causative of male infertility.

Call for a group leader in Evolutionary Biology The IGFL @igflyon.bsky.social in Lyon, France, is recruiting a group leader in Evolutionary Biology. An exciting place for exploring the interfaces of evolution with physiology and development. #EvolBiol #ecoevo #evodevo tinyurl.com/evolbiol

LoL-align is out in @natmethods.nature.com! It aligns protein structures without superposition. More sensitive than TM-align and DALI, producing better alignments 5–20× faster. Now available in Foldseek! 📄 www.nature.com/articles/s41... 💾 github.com/steineggerlab/foldseek 🌐 search.foldseek.com

We're hiring! My department at the University of Oregon is searching for a new colleague at the rank of Full Professor in Genetics/Genomics (broadly defined) It's an endowed chair position Fantastic chance to join a collaborative community of biologists careers.pageuppeople.com/726/cw/en-us...

How does embryonic patterning remain robust when temperature changes the pace of development? In medaka, morphogen gradients rescale with developmental speed, despite morphogen diffusion remaining unchanged. Simulations point to a reaction-dominated mechanism. 👉 doi.org/10.64898/202...

Our work is finally out! How do organs get the right shape and size on time? Using the zebrafish inner ear canal, we show that a mechanical feedback loop between the ECM and Yap1 drives timely tissue growth, and a built-in termination system shuts it down once morphogenesis is done.

6-month internship to explore (genome-wide) enhancer-promoter interactions in the crustacean Parhyale – Hosted by the Averof and Ghavi-Helm teams at IGFL Lyon – Early 2027 – Student (any level) with some prior experience in mol biol – Stipend 695 €/month

New work from Lukas Ruber's lab finds a common signature of intron shortening and class-specific depletion of TEs in developmentally truncated Cypriniformes, including Danionella fishes. www.pnas.org/doi/10.1073/...

#fish 🐟 🐠 researchers and PIs of tomorrow! We like to sponsor you for an Ecology, Evolution and Behavior (EEB) Presidential #Postdoc Fellowship application @michiganstateu.bsky.social. Applications due Nov 1, so get in touch soom! #EndlessFishMostBeautiful www.fishevodevogeno.org Pls repost!

DNA → RNA → protein. From single mRNAs to an entire developing vertebrate embryo, we can now watch this last step unfold in real time. Our paper is out today! 🐟🔬 www.science.org/doi/10.1126/...

BREAKING NEWS The 2026 Nobel Prize in Physiology or Medicine has been awarded to Karl Deisseroth, Peter Hegemann and Georg Nagel “for their discoveries concerning light-gated ion channels and optogenetics.”

ICYMI: New online! Zebrafish relatives as models for functional comparative genetics and genomics

Analyse your teleost skeletal muscle section with fishROI - Now published: link.springer.com/article/10.1...

🧬🔬 Why are enhancers transcribed and how does that impact gene regulation? I’m really excited to share our new paper in @science.org showing that noncoding RNAs control the timing of gene activation in embryos. With Mike Levine #ScienceResearch @columbiamed.bsky.social A few highlights below... 🧵👇

New online! Zebrafish relatives as models for functional comparative genetics and genomics

🐟 1st German Fish Model Research Meeting | Sept 16–18, 2026, Heidelberg. ~200 participants, 40 talks, 75 posters. Keynotes: Tilly Mommersteeg, Laure Bally-Cuif, Ferenc Müller. germanfishmeeting.org #Zebrafish #FishModels

The first Danionella paper from the lab. Danionella cerebrum is transparent, so you can see all of the internal organs. But what sensory information are the organs sending to the brain? In our new preprint, Emily Bayer wanted to find out. 1/4 www.biorxiv.org/content/10.6...

Whole-body cellular activity imaging in zebrafish, headed by Virginie Ruetten @vmsruetten.bsky.social - new paper is out: www.nature.com/articles/s41...

Ready to take the next step in your research career? 👨‍🔬 We're seeking an outstanding researcher to establish an independent research program as an EMBL Australia Group Leader at the Australian Regenerative Medicine Institute (ARMI) @monashuniversity.bsky.social 🗓️ Apply by 2 October 🔗 bit.ly/4qHYtjb

A developmental biologist's guide to mechanics, just out in Development! In which we learn about the three pillars of any mechanical model: forces, mechanical properties, and boundary conditions. @pflenne.bsky.social @alessandrochppr.bsky.social @caojialing1002.bsky.social @dev-journal.bsky.social

🧵 What if one reason fertility declines with age isn’t just genetic-but mechanical? Thrilled to share our new paper in @NatureCellBio : Elevated contractility drives implantation failure in mouse embryos from aged females… here’s what we found 👇 www.nature.com/articles/s41... 1/11

Happy to see Ashley's paper out @natphys.nature.com www.nature.com/articles/s41...

Here it is! Bonsai. Now there is really no more excuse for using t-SNE/UMAP. Bonsai not only makes cool pictures of your data. It actually rigorously preserves its structure. No tunable parameters. Incredible work by @dhdegroot.bsky.social. I'm so excited about this! www.biorxiv.org/content/10.1...

We are gathering feedback from our readers, authors and reviewers about the use of AI tools in scholarly publishing. Have your say at: www.surveymonkey.com/r/ZBFC663

New online! Genetics and genomics of hybridization

New primer on Danionella cerebrum, with @xinwei-wang.bsky.social . What a fun little fish :) Free access here: authors.elsevier.com/a/1ndEe_LsQS...

Are you an ecologist/evolutionary biologist looking for an ongoing academic position? Monash University’s School of Biological Sciences is hiring! Come join us in Melbourne, Australia! Details here: careers.pageuppeople.com/513/cw/en/jo...

Ensembl is moving this week! 🧬 Links will point you to the new Ensembl. The default site will be ensembl.org for all species from across the tree of life. We’re starting with the Ensembl Genomes sites, and we’ll end with the Ensembl 116 site.

NEW GRANT OPPORTUNITY! Ever wanted to travel to a different lab to learn more? Or expand your knowledge and experience in the field? #IZFS has a new grant opportunity for you! Read more about the Knowledge Exchange Grant here: www.izfs.org/awards/knowl... #ZebrafishGrant

"The importance of a model is choosing one that allows you to address the question that you’re setting out to address." Sage advice from Prof. Judith Eisen (University of Oregon), Pioneer of Zebrafish Research & 2024 George Streisinger Award Winner. #ZebrafishFunFacts 🧪

How did octopuses evolve novel traits? Rishav Mitra, Richard Han, Trey Scott, et al serendipitously discover a unique ribosome adaptation that increases the accuracy of protein synthesis and evolved alongside their elaborate nervous systems vs deep sea relatives. www.biorxiv.org/content/10.6...

No better way to head to #EZM2026 than with a freshly published success! Our eLife paper is now out: elifesciences.org/articles/107.... We show optimised prime editing in zebrafish for precise DNA substitutions and insertions. Huge thanks to the fantastic team #Zebrafish #GenomeEditing #eLife

We're excited to present a single-cell atlas of vertebrate cranial motor neuron development, the first story from my postdoctoral work in the Moens lab, up now on bioRxiv!

How do dozens of distinct muscles emerge from the same pool of precursor cells? Our new Science Advances paper uncovers the developmental logic that coordinates myoblast identities to build diverse muscles. 📄 www.science.org/doi/10.1126/... #DevelopmentalBiology #Drosophila #Muscle

I am excited to announce the latest paper from our lab, published in Science ! In this study, we show that thalamocortical-like circuits in the zebrafish brain process sensory information hierarchically across topographically organized forebrain circuits.

Dear Friends, I just published an insightful review on neural crest evolutionary origin and later transformations. “Co-option and innovation in neural crest evolution”: www.science.org/doi/10.1126/...

What if an embryo made immune cells before it finished building the tissue they usually come from? In our new preprint, we show that annual killifish embryos specify neutrophils before germ layers are fully resolved. www.biorxiv.org/content/10.6... Huge thanks to my PI, @ohnolog.bsky.social ! 🧵

Annual killifish continue to surprise us: they make neutrophils before almost every other cell type, even before gastrulation. Neutrophils usually arise from the lateral plate mesoderm (forming in cyan), but in killifish they are already patrolling around the embryo in gold. tinyurl.com/killiphil

We read an entire scroll — without ever opening it PHerc. 1667, sealed since the eruption of Vesuvius in 79 AD, has been virtually unwrapped and read from beginning to end scrollprize.org/firstscroll The Herculaneum Papyrus Scrolls project www2.cs.uky.edu/dri/herculan... #books #old_Manuscripts

🔥 Published today, and just in time for summer conferences, here are your guidelines for presenting badly www.nature.com/articles/s41... rdcu.be/fqa92

Excited to share the final published version of our work on the evolution of dorsal-ventral patterning in fins and limbs, now up on @currentbiology.bsky.social In review we added new single LARM element deletions to assess their impact on dorsality. Take a look! 🔬🧪🐟🐁 www.cell.com/current-biol...

IMPORTANT study from @hocinerekaik.bsky.social @denisduboule.bsky.social and a significant validation of SCBEMs, #gastruloids in particular, as a discovery tool www.biorxiv.org/content/10.6... 🧵

As Editor of @dev-journal.bsky.social I get asked "What are you doing about your impact factor?" In our new editorial we say: Ask not what Dev can do for the impact factor. Ask what you can do for Dev's IF The IF is about how we all cite, review & assess each other's work doi.org/10.1242/dev....

In memory of David Hockney: Your Outer Fish #FishArt

Just a few months to IVBM in Australia! Come down and enjoy great science, food, beaches, wine and company. Time to register now at ivbm2026.com

Dear all, please join my @isrbio.bsky.social webinar on how danionin fishes grow skeletal muscle. Tomorrow via Zoom. Details here: isrbio.org/webinars