Martin Taylor

Apply for a @ukri.org Future Leaders Fellowship and get hosted at IGC! We welcome applications from ECRs seeking to establish an independent research group across a range of disciplines aligned with our research strengths in genetics and cancer. Apply by 30 Nov. Find out more here 👉 edin.ac/4jCzJay

Big paper alert! This project has been years in the making. A comprehensive description of somatic mutation rates and signatures across 53 tissues or cell types using NanoSeq. A large collective effort led by Mimy Pham, Mike Stratton and @r-rahbari.bsky.social. www.biorxiv.org/content/10.6...

Engines of genetic diversity... Transgenerational lesion segregation in worms, very nice work by Aaron Quinlan @aaronquinlan.bsky.social & Thomas Sasani

Finishing your PhD or looking for a post-bac research position? We’re recruiting postdocs and research technicians to study somatic evolution! Come do interdisciplinary science in a friendly, collaborative environment at @harvardmed.bsky.social Genetics www.naxerova.hms.harvard.edu/contact

🔬NEW PREPRINT🔬 Explainable machine learning relates histological to genomic pathology www.biorxiv.org/content/10.6... From John Connelly and Barbara Hernando @bhernando.bsky.social, co-led with Martin Taylor @mstaylor.bsky.social - along with others from #LCEConsortium #genomicPathology #ml #ai

Thread from @s-j-aitken.bsky.social explaining our new paper that finds strong epistatic interactions between germline genetic background and somatic driver mutations that set the course of cancer development.

new out in Nature www.nature.com/articles/s41...

Please help me find a great student! I have a PhD position in my lab in Munich, looking at the dynamics of DNA damage and repair from chemotherapy: jobs.dkfz.de/en/jobs/1686... The application deadline is 02.07.26 @dkfz.bsky.social @lmu-klinikum.bsky.social

Interested in DNA damage and the mechanisms of mutagenesis? We are hiring post-doctoral scientists as part of the amazing CAUSE Cancer Grand Challenge team. Biochemistry, genomics and computational biology... tinyurl.com/yc5xs3wa tinyurl.com/4unu5uu9 CAUSE www.cancergrandchallenges.org/cause

📖 My book BEYOND INHERITANCE is out today. tinyurl.com/5yjsr97n This journey started with a fact I couldn’t ignore: Even in otherwise healthy adults, mutant cells can appear in the blood—quietly doubling the risk of heart disease and stroke.

A whole new world… Inigo Martincorena presents paradigm shifting work showing a key role for somatic evolution in autoimmune disease. Long-term, polyclonal, multistage evolution #MITS2026

We’re excited to reveal that team CAUSE led by Ludmil Alexandrov at @ucsandiego.bsky.social has been selected by @cancergrand.bsky.social to receive up to $25m over approx 5 years to take on one of cancer’s toughest challenges. Congratulations @mstaylor.bsky.social from IGC & team: edin.ac/4kYC1iR

The exciting next instalment of Mutations in Time and Space... Open for registration now

I'm very pleased to announce the official publication of our lab's paper "DNA mutagenesis driven by transcription factor competition with mismatch repair" in today's issue of Cell! www.cell.com/cell/abstrac...

IGC is looking for a Core Facility Bioinformatician to provide bioinformatics expertise and support to researchers across the Institute, working at the intersection of computational and experimental science. Find out more and apply by 13 October: edin.ac/3R5dEBU @cmvm-edinburghuni.bsky.social

Would you like to do some unique experiments in cancer genomics and mutagenesis, in beautiful Munich? Well then apply for this PhD position: jobs.dkfz.de/en/jobs/1679... You'll learn a lot and it'll be fun and interesting! #DKTK @dkfz.bsky.social @lmumuenchen.bsky.social

🔬Under the microscope: DNA damage tracked through cell generations🔬 It was a pleasure to write this #NewsAndViews with our PhD student Emma Reilly, online today @nature.com rdcu.be/em0qi @cruk-ci.bsky.social @spjacksongroup.bsky.social @yalepathology.bsky.social @yalecancer.bsky.social

My lab at hiring! - we have TWO postdoc positions (one computational, one wet lab focussed) at Yale @yaleschoolofmed.bsky.social, working closely with our group members at University of Cambridge, UK @cambridgeuni.bsky.social Please help to spread the word! Adverts with full details below ⬇️

This is just brilliant. New tool dissects immune profiles from WGS. Gives novel insights into >90k (!) tumours, highlights circulating immune changes https://buff.ly/41y6Hzz Found with researchbriefing.com

In science, we often see weird blips in the data. The question: is it artefact (usually!), or something new & exciting? We don’t always have time to dig deep. Our paper in @nature.com today came from just such a blip. So don’t ignore the weird stuff. Pull on that thread...

To what extent is cancer development deterministic and predictable..? Does the germline genome affect that predictability...? Preprint: www.biorxiv.org/content/10.1...

🌟NEW PREPRINT ALERT!🌟 We are very pleased to introduce #StrainDifferences: “Genetic background sets the trajectory of cancer evolution” www.biorxiv.org/content/10.1... 🧵[1/12]

Building on our discovery of #LesionSegregation, @mikespencerchapman.bsky.social and colleagues from @sangerinstitute.bsky.social find that some DNA lesions can persist in humans for months or years! "Prolonged persistence of mutagenic DNA lesions in somatic cells" www.nature.com/articles/s41...