Nicole Repina

We are very happy to announce the next edition of the Venice summer school in #EvoDevo This year's theme: How do complex morphologies emerge in development and evolution? 💫🌿🐚🐙🦋🫎 Check out our wonderful line-up of teachers and apply!!! 👇👇👇 #morphogenesis #growthandform #VeniceEvoDevo

Do you want to learn about multiplexed image analysis using OME-Zarr? Tomorrow, @rhornb.bsky.social , @nrepina.bsky.social & Flurin Sturzenegger will share their learnings about building workflows around multiplexed image analysis, see www.biovisioncenter.uzh.ch/en/events/Up...

Thank you @florianjug.bsky.social !! It was such a pleasure

When tension increases, the nucleus escapes. New paper out in @natphys.nature.com. Check out Tom's thread for a summary 👇

New Toettchlab paper alert! Harrison Oatman just published his beautiful work combining software design for "smart" microscopy+optogenetics and some really beautiful work understanding EGFR-driven collective cell migration. www.cell.com/cell-systems...

Introduced by Bernhard Riemann in the mid-19th century, manifolds are crucial to our understanding of the universe.

🔥 Published today, and just in time for summer conferences, here are your guidelines for presenting badly www.nature.com/articles/s41... rdcu.be/fqa92

Here the published version of our work on uncoupling different types of tissue phase transitions during development! Find out more on how contact surface tension-driven rigidity transitions trigger tricellular junction formation and initiate epithelial organization! @natphys.nature.com

Tune in this coming Monday on zoom! I'll be presenting work from my PhD @slcuplants.bsky.social on how plants regulate their shoot branching architecture via auxin, strigolactone, and BRC1.

Multinucleate cells challenge deeply-held assumptions about complexity, ecological success and evolution. Postdoc extraordinaire and gifted writer @mrosjac.bsky.social tackles this subject with aplomb - tell us what you think! www.sciencedirect.com/science/arti... @currentbiology.bsky.social

Nature research paper: A deep-learning framework reveals whole-body perturbations at cell level go.nature.com/3Pjox61

Our latest: Minimal essential requirements for neural tube self-organisation How does a single cell give rise to a tissue with the right cell types in the right proportions? We deconstruct and rebuild a self-organising tissue from first principles A thread🧵 www.biorxiv.org/content/10.6...

📢📢 We are hiring a Bioimage Analyst at the BioVisionCenter! 📢📢 Join our collaboration with the Flow Cytometry Facility and contribute back to the international efforts on open standards for bioimaging data! More information here, reach out if you have any question: jobs.uzh.ch/job-vacancie...

Check out our 2026 subject collection, showcasing recent papers in @dev-journal.bsky.social on evolutionary developmental biology: journals.biologists.com/dev/collecti... It has been curated to support the 2026 Euro-Evo-Devo conference in Glasgow, UK. #EED2026

Our latest work on shape-programmable tissues is out in @science.org. By positioning topological defects in cellular nematics, we encode frustrated 2D force fields that relax into predictable 3D shapes. Collaboration with Marino Arroyo’s lab, led by @pauguillamat.bsky.social at @ibecbarcelona.eu.

Check out 2 papers and a related Perspective on tissue regeneration in @science.org this week Species-specific oxygen sensing governs the initiation of vertebrate limb regeneration | Science www.science.org/doi/10.1126/...

I know this tension all too well! Thank you for the highlight

How it feels doing literally any task right now.

A question I get asked all the time by @dev-journal.bsky.social authors "Why does it cost so much to publish a paper?" We break down the finances and explain where the money goes Spoiler: quality publishing takes a village (people + infrastructure) journals.biologists.com/dev/article/...

3 DAYS LEFT to submit your abstract!! Don’t miss your chance to present at the Cambridge Morphogenesis Symposium. 👉 Submit & register here: t.ly/YYM3u #Morpho5

We’re excited to share our latest preprint on Fractal: our approach towards FAIR bioimage analysis at scale with OME-Zarr-native workflows. Fractal defines interoperable tasks on OME-Zarr and provides a platform for TB-scale image analysis. (1 / 10🧵) www.biorxiv.org/content/10.6...

📢We are excited to announce the Cambridge Morphogenesis Symposium - a full day event at SLCU @slcuplants.bsky.social (and virtually) on 5 June 2026! 🎉Come celebrate the 5th anniversary of the seminar series! 🚩Register & submit abstracts by 3 April! Check out the details: t.ly/YYM3u Please repost!🙏

Peer Bork died yesterday 💔 which shocked me. In 2003 I did a short-term fellowship in Peer’s lab because I idolized him. I met Martin there & we wrote this paper together. Peer was great at bringing people together; a master collaborator with a rare ability to think up big ideas.

In need of a positive outlook on the future (of developmental biology)? Read our perspectives by my fellow @dev-journal.bsky.social PI fellows and myself. I'm hoping my future will contain much more TE biology and mammalian genome regulation! journals.biologists.com/dev/article/...

How do #stemcells integrate information to coordinate fate decisions? Delighted to finally see our work showing how growth factors regulate the mechano-osmotic state of the #nucleus and #chromatin to control #pluripotency exit out! www.nature.com/articles/s41... see 🧵 👇

The reality in science is that creativity is not treated as a core skill while hypothesis testing is, and that is the imbalance that we want correct through the Night Science Institute! www.technologynetworks.com/genomics/art... www.night-science.org

Great commentary, we all need to understand this

Hydra body axis balance: a fight between two transcription factors This Research Highlight showcases the work from Jaroslav Ferenc, Marylène Bonvin, Panagiotis Papasaikas, Jacqueline Ferralli, Clara Nuninger and Charisios D. Tsiairis: journals.biologists.com/dev/article/...

Out in @science.org! We found that the intestine doesn’t just push out cells when crowded. Instead, cells are in a mechanical tug-of-war, and weaker ones are extruded. A new view of how our gut keeps its balance and stays healthy. www.science.org/doi/10.1126/...

What a week! A huge thank you to all the students and teachers for the for the engaged discussions, thoughtful questions, and good vibes. Rock on, and stay curious! 🤓 ✨ #VeniceEvoDevo #levels #morphogenesis #sysbio #evodevo

We are all super happy and proud to see our work on the function and evolution of the #cephalic #furrow published in @nature.com. Let me say a few things about the background and history of this work on the #Evolution_of_Morphogenesis (1/12)

BIG NEWS!! We will be hiring a new professor with 25 years of endowed funding at the @biozentrum.unibas.ch @unibas.ch, focused on using biophysics and structural biology to explore climate-related fundamental science topics. Come start an innovative research cluster with us! 🧪🔬🧶🧬🌾🌍

We're happy to announce the 2025 International OME-NGFF workshop 🎉 📅 Dates: - Symposium: Nov 10–11, 2025 - Hackathon: Nov 12–14, 2025 📍 Location: Zurich, Switzerland Full details & registration: www.biovisioncenter.uzh.ch/en/events/Up...  #bioimaging #openscience #OMENGFF #OMEZarr (1/x 🧵)

A closed feedback between tissue phase transitions and morphogen gradients drives patterning dynamics https://www.biorxiv.org/content/10.1101/2025.06.06.658228v1

Our latest "Dynamic Landscape Analysis of Cell Fate Decisions: Predictive Models of Neural Development From Single-Cell Data" A rigorous mathematical foundation for Waddington's landscape to study cell fate decision making Applied to ventral neural tube development www.biorxiv.org/content/10.1...

🚨📣 New preprint alert! Excited to share my new postdoc work on direct force and mechanical properties measurements in live embryos! A great team effort with A. Chamolly (theory), under the supervision of F. Corson and @jeromegros.bsky.social 📄 www.biorxiv.org/content/10.1... #devbio #mechanics

This is so reasonably wonderful!!!!! 🤩

Last chance to come join us, don’t forget to apply (by tomorrow March 31st)!!!

Deadline is TOMORROW night (Mar 31). Not tonight, like wrongly announced at first. And that's good news: because you get another 24hrs to apply, if you have not yet done so! What are you waiting for!? 😉 Registration link below:

Our teachers this year: Mihaela Pavličev Mihaela co-chairs the Department of Evolutionary Biology at Uni Vienna. She studies mammalian reproduction to understand how organismal organization affects variation. She will present a model of tissue evolution based on metabolic interdependence.

Our teachers this year: Thibaut Brunet (@thibautbrunet.bsky.social) Thibaut studies the evolutionary origin of animal morphogenesis at Institut Pasteur in Paris. He will be teaching us about this and also how multicellularity first arose in evolution.

Our teachers this year: Wallace Marshall (@wallaceucsf.bsky.social) Wallace studies how cells solve engineering problems, how geometry arises within cells, and how it shapes and constrains cellular behavior. He'll be telling us how cell shape constrains underlying pathways.

Our teachers this year: Dan Brooks (@dsbrooks.bsky.social) Dan's research interests span the history & philosophy of the life sciences, concept usage in science & theory in biology. At our school, he'll have a thing or two to say about levels of organization, what they are & where they come from.

Well well, timely! 😉 www.cell.com/cell-systems...

Nature research paper: Topological segregation of stress sensors along the gut crypt–villus axis https://go.nature.com/4b4jcpC

Our teachers this year: Nicole Repina (@nrepina.bsky.social) Nicole is using quantitative imaging to study how complex tissue shape can emerge from cell interactions. In Venice, she will be speaking about how we can use imaging for multiscale analysis of multicellular systems.

Our teachers this year: James DiFrisco James is a philosopher of science and theoretical biologist working @crick.ac.uk on the evolution of gene regulatory networks, modularity and pleiotropy, vertebrate gastrulation, and the developmental basis of morphological homology/tissue organization.

📢‼️ Exciting new preprint from the lab by @nikhil-mishra.bsky.social et al, now out on @biorxivpreprint.bsky.social, reveals that the early embryo geometry spatiotemporally patterns zygotic genome activation (ZGA) in zebrafish. 🐟 tinyurl.com/Biorxiv-nmis... Read on to learn more... 👇

*** Registration deadline approaching! Apply to our Summer School in Evolutionary Systems Biology in Venice before MARCH 31, 2025 Reflect on your science in a beautiful and inspiring environment! Food & accommodation for the whole week are included in the course fee. Registration link below.