The Probst Lab

uni-due.deStellenausschreibung

25 Aug

Not too long left to apply to this great position here in Essen with us! Come work on ERC project Archean Park and uncover carbodioxyphilic metabolisms around the world! 🌋🧬🥼💻

The Probst Lab@probstlab.bsky.social

We're looking for a Postdoctoral Researcher (f/m/d) for the ERC Synergy project “Archean Park”! 📍 Location: Essen, Germany ⏱ Duration: 36 months (Full-time | EG 13 TV-L) 📅 Start Date: As soon as possible ⏰ Application Deadline: September 2, 2026 www.uni-due.de/karriere/ste...

The Probst Lab reposted

André Soares

@geomicrosoares.bsky.social

7 Aug

Come work with us, we're really cool people to hang out with 😁 You'll get to do interdisciplinary research exploring microbial metabolisms during the Archean Eon by investigating the deep biosphere in high-CO₂ ecosystems hundreds of meters below ground. Please retweet and spread the word! 🧬 💻

The Probst Lab@probstlab.bsky.social

uni-due.deStellenausschreibung

uni-due.deStellenausschreibung

7 Aug

7 Aug

Join our team to explore microbial metabolism during the Archean Eon by investigating the deep biosphere in high-CO₂ ecosystems hundreds of meters below ground! 🌎 Please share as much as possible! Thank you! @unidue.bsky.social

2 Apr

🤯 Manual MAG refinement? Still doing it by hand?? We’ve been there... You could just leave those messy, ill-assigned contigs/scaffolds in your data for NCBI to pick up during your submission… …OR you could add itBins, our new automated MAG refiner by @jmk-ude.bsky.social, to your pipeline!! 🔥

2 Apr

👉 Read the preprint, led by @jmk-ude.bsky.social: www.biorxiv.org/content/10.6... Let us know what you think, and leave no MAG unrefined! github.com/ProbstLab/it... 🐍 $ mamba install bioconda::itbins @geomicrosoares.bsky.social @alexjprobst.bsky.social @unidue.bsky.social @unimarburg.bsky.social

biorxiv.orgbiorxiv.org

We’re out and about yet again, this time in the vulcanic Eifel region drilling with Jens Kallmeyer @gfz.bsky.social 🌋

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7 Mar

@alexjprobst.bsky.social look at this, we’re drilling over here!! 🥳

11 Mar

I mean look at this baby! Right out from 115m depth! 🔥🔥

We’re out and about yet again, this time in the vulcanic Eifel region drilling with Jens Kallmeyer @gfz.bsky.social 🌋

@geomicrosoares.bsky.social @katharinasures.bsky.social @feriel.bsky.social @pengyaoz.bsky.social

@unidue.bsky.social @erc.europa.eu

4 Dec 2025

Near-zero temperatures, but field sampling is still a-go for the Probst lab 😎 @geomicrosoares.bsky.social @feriel.bsky.social @pengyaoz.bsky.social are out in Regensburg! @unidue.bsky.social @uniregensburg.bsky.social

doi.orgAcquisition of Spacers from Foreign Prokaryotic Genomes by CRISPR-Cas Systems in Natural EnvironmentsAbstract. Clustered regularly interspaced short palindromic repeats (CRISPR) and CRISPR-associated (Cas) systems of bacteria and archaea provide immunities

17 Nov 2025

We are excited to share @probstlab.bsky.social's latest publication on the diversity of CRISPR-Cas spacers, led by @katharinasures.bsky.social !! 🧬 Have a read!! ➡️ doi.org/10.1093/gbe/... @emilruff.bsky.social @alexjaffe.bsky.social @geomicrosoares.bsky.social & others not in Bluesky!

17 Nov 2025

We analysed more than 1 TB of sequencing data and discovered that CRISPR-Cas systems in two subsurface environments acquire spacers matching multiple prokaryotes in the same environment. This provides an explanation for some of the many unmatched spacers in public databases. @unidue.bsky.social

nature.comA roadmap for equitable reuse of public microbiome data - Nature MicrobiologyIn this Consensus Statement, a consortium of microbiome scientists discuss current sequencing data sharing policies and propose the use of a Data Reuse Information (DRI) tag to promote equitable and collaborative data sharing.

30 Sept 2025

Our own @alexjprobst.bsky.social @geomicrosoares.bsky.social and Cristina Moraru have recently authored a @natmicrobiol.nature.com Consensus Statement where they discuss new mechanisms for sequencing data reuse! 🧬💻 Check out their manuscript here: www.nature.com/articles/s41...

30 Sept 2025

They made up the Data Reuse Core Team along with @lhug.bsky.social @environmicrobio.bsky.social @folker.bsky.social and had the support of the Data Reuse Consortium, composed of 167 scientists globally who were pivotal in driving this effort forward! Thank you all! 🧬 @unidue.bsky.social

biorxiv.orgUranium mining fuels evolution in deep groundwater microbiomesMicrobial communities in the deep biosphere underpin global biogeochemical cycles, yet their evolutionary responses to extensive anthropogenic disturbances remain unclear. Uranium in-situ leaching (IS...

Fresh out of the oven! 🍞 We're happy to see this preprint out, fruit of a recent collaboration with @wei-biogeochem.bsky.social! 🧬💻 Small 🧵 below going through the main points 👇 www.biorxiv.org/content/10.1...

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We tracked nucleotide diversity in MAGs across different mining stages, which suggested widespread mutational pressure under long-term environmental stress!

@alexjprobst.bsky.social @geomicrosoares.bsky.social & Till Bornemann from our group were part of this effort! Shoutout to the remainder collaborators at the China University of Geosciences, and Jon Lloyd at the University of Manchester (@manchesterup.bsky.social). @unidue.bsky.social & others RT!

We leveraged #metagenomics & #metatranscriptomics data to estimate microdiversity in groundwater at different stages of U mining. We show that U in-situ leaching drives significant alterations in 🦠 community composition, oxidative stress, biogeochemical cycling, and overexpression of 🧬 repair genes

31 July 2025

Please RT this awesome opportunity to do a PhD at @unidue.bsky.social in collaboration with @jgi.doe.gov!! 🔥 Thanks!

André Soares@geomicrosoares.bsky.social

The Central Collection of Algal Cultures (CCAC) at @unidue.bsky.social is advertising a 3-year PhD position supervised by the current Curator, Dr. Olga Matantseva! This PhD will take place in close collaboration with the @jgi.doe.gov. 🦠🧬💻 Apply here: www.uni-due.de/karriere/ste...

16 July 2025

We’re happy to announce Dr. Lennard Stach!! 🥳🥳 Well done Lennard for a brilliant defense and thesis!! We will miss you! Finally, thank you @leeselab.bsky.social for sitting in the thesis committee! 🫶

13 June 2025

Our @umweltstiftung.bsky.social fellow Linda Labecka presented her work at the most recent DBU conference! She works closely with the Institute for Artificial Intelligence in Medicine (@unidue.bsky.social & University Medicine Essen) and Universitätsklinikum Bonn (@unibonn.bsky.social)! 🧬💻

enviromicro-journals.onlinelibrary.wiley.comDifferential Expression of Core Metabolic Functions in Candidatus Altiarchaeum Inhabiting Distinct Subsurface EcosystemsMajor differences between Candidatus Altiarchaeum species living in two distinct subsurface ecosystems as determined via metatranscriptomics. Genes overly expressed in different Ca. Altiarchaea in Mu...

4 June 2025

Our latest work is out - here, our own Dr. Sarah Eßer compares transcriptomic patterns of Altiarchaeum in Crystal Geyser (US) and the Muehlbacher sufidic spring (Germany)! 🧬 Read more below: enviromicro-journals.onlinelibrary.wiley.com/doi/10.1111/...

30 May 2025

Excited to welcome @hsintunglai.bsky.social and @renaandraes.bsky.social as PhD students to our group!! They will be working within Phase 2 of @crc-resist.bsky.social @unidue.bsky.social under the supervision of @alexjprobst.bsky.social and @cristinamoraru.bsky.social.

3 Apr 2025

#TBT to @joernstarke.bsky.social and @katharinasures.bsky.social presenting their amazing work at the @vaam-microbes.bsky.social AC 2025 which took place at @ruhr-uni-bochum.de just last week! Well done you two! @crc-resist.bsky.social @unidue.bsky.social

31 Mar 2025

Here's our latest group photo! Our lovely team keeps growing, as does our enthusiasm for doing great science together! 🦠🧬

We’re looking forward to meeting all our science friends at the @vaam-microbes.bsky.social Annual Conference 2025 at @ruhr-uni-bochum.de !! 🧬🦠 On our side, we’re exceptionally giving two talks about our latest work: ⬇️

On Tuesday 12.30pm at Lecture Hall 7, our own Jörn Starke is presenting on “Flow Velocity and Anthropogenic Stressors Drive Microbial Community Dynamics in Riverine Ecosystems”, right out of @crc-resist.bsky.social and our role at @unidue.bsky.social in that project! 🏞️

Here’s @joernstarke.bsky.social !! 🥳

Then on Wednesday 9.30am at Lecture Hall 5, @katharinasures.bsky.social who recently started her PhD with us will tell us more “New insights into the spacer diversity of CRISPR-Cas systems in natural environments”, a collab with @emilruff.bsky.social ! 🧬💻

17 Mar 2025

Super happy to be hosting Prof. Richard Allen White III AKA @raw937.bsky.social from the University of North Carolina at Charlotte at @unidue.bsky.social for 3 surprisingly sunny weeks!! Great to have you around Rick!! 🦠🧬

doi.orgInferring replication states of bacteria and viruses in enrichment cultures via long-read sequencingAbstract. Most microorganisms cannot be cultured in isolation, necessitating sophisticated methods for studying their (eco)physiology. While numerous appro

11 Mar 2025

Want to know who’s replicating and who’s just hanging out in your enrichment cultures? Our new study led by @soansi.bsky.social shows how @nanoporetech.com long-read sequencing can reveal replication states, shedding light on microbial growth. 🦠🧬 See our latest publication: doi.org/10.1093/isme...

11 Mar 2025

Our 🦸 team included: @alexjprobst.bsky.social @geomicrosoares.bsky.social @emilruff.bsky.social @cristinamoraru, Till Bornemann, Adrian Lange, @leagriesdorn.bsky.social , Adrián Fuentes, Marie Dieckmann, Beate Krok, Michael Hügler @unidue.bsky.social

doi.orgA uniform stress response of stream microbiomes in the hyporheic zone across North AmericaBackground Stream hyporheic zones represent a unique ecosystem at the interface of stream water and surrounding sediments, characterized by high heterogeneity and accelerated biogeochemical activity. ...

20 Feb 2025

Is stress response in stream sediments uniform across catchments? 🌊🦠 With @TheWrightonLab at CSU, we built river MAG & gene DBs and used metaT data to explore this while uncovering active stream microbiome metabolic functions! Read our preprint here: doi.org/10.1101/2025... @unidue.bsky.social

20 Feb 2025

Quick PSA: we’ve officially deactivated our profile on Twitter/X and will henceforth only use Bluesky to communicate our science 😁

cristinamoraru.bsky.social

13 Jan 2025

We’re kicking off our Archean Park ERC project at @uni-muenster.de with @alexjprobst.bsky.social Jens Kallmeyer, Ivan Berg and Kai-Uwe Hinrichs & respective groups! Thanks very much to @donatogiovannelli.bsky.social and Prof. William Martin for giving invited talks to get us started!

The Probst Lab reposted

@cristinamoraru.bsky.social

20 Dec 2024

@probstlab.bsky.social @crc-resist.bsky.social #1 on virus-host stress response in rivers tinyurl.com/43cjd6es #2 on microbial & epigenetic stress response in rivers tinyurl.com/bdf8eu5a @alexjprobst.bsky.social @unidue.bsky.social Pls RT!

@geomicrosoares.bsky.social

The Probst Lab reposted

André Soares

20 Dec 2024

We're hiring two bioinformatics-focused PhD students - one on microbial & epigenetic stress response in rivers, another on virus-host stress response in rivers! 🧬🦠💻 @unidue.bsky.social @cristinamoraru.bsky.social Please RT & spread the word - the @probstlab.bsky.social awaits you! 🦸 @idw-online.de

Alex Probst@alexjprobst.bsky.social

#PhD #position #alert 2 bioinfo PhD positions @ProbstLab @RESIST_CRC #1 on microbial & epigenetic stress response in rivers tinyurl.com/bdf8eu5a #2 on virus-host stress response in rivers tinyurl.com/43cjd6es (supervision Moraru) Please share!

@danielheringude.bsky.social

The Probst Lab reposted

Daniel Hering

19 Dec 2024

Interested in multiple stressor research in rivers? Interested in a PhD under excellent supervision in one of Europe’s largest freshwater research centres? We seek 8 doctoral researchers for the CRC RESIST at the University of Duisburg-Essen! sfb-resist.de/people/open-... #rivers #PhDjobs

19 Dec 2024

We’re hiring!! Come do a PhD with us using -omics to better understand river microbiomes responses to drought processes! ⬇️

Alex Probst@alexjprobst.bsky.social

The Probst Lab reposted

Alex Probst

@alexjprobst.bsky.social

19 Dec 2024