MitoStarsLab

MitoStarsLab

@richterlab.bsky.social

We are dedicated to improving the life of patients with mitochondrial disease by understanding the mechanisms that underlie their untreatable maladies. https://www.ncl.ac.uk/nuact/fellows/profiles/uwerichter/

1K followers430 following4 posts

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Micah
@rincewind.run

a remarkably effective life hack: just be nice to people it's incredible how much goodwill people will extend to you if you're pleasant to them

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Paris Marx
@parismarx.com

The days of Google Docs are ending; we enter the age of Docs, made by France's Interministerial Directorate for Digital Affairs and Germany's Center for Digital Sovereignty of Public Administration. We need more governments to collaborate on public software projects to achieve digital sovereignty.

techspot.comFrance and Germany unveil Docs, a homegrown alternative to Google DocsThe Trump administration has set out to drastically reshape the relationship between the US and Europe. In response, Brussels is scrambling to adapt to this new reality,...

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Lee Sweetlove
@leesweetlove.bsky.social

Lots of excellent advice in this piece. The core message - only through writing do you really think and order your thoughts into logical sense. Makes a case for not using AI for 1st draft because you bypass the thinking step www.nature.com/articles/s41... @naturebiotech.bsky.social #PlantScience

nature.comAn open letter to graduate students and other procrastinators: it’s time to write - Nature BiotechnologyNature Biotechnology - An open letter to graduate students and other procrastinators: it’s time to write

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Agnel Sfeir
@agnelsfeir.bsky.social

Combining bacterial end joining with programmable nucleases, we induced mtDNA deletions in human cells at varying heteroplasmy and examined their metabolic and cellular effects. Simple tool to apply across any cell type and engineer pathogenic mtDNA deletions. www.sciencedirect.com/science/arti...

sciencedirect.comEngineering mtDNA deletions by reconstituting end joining in human mitochondriaRecent breakthroughs in the genetic manipulation of mitochondrial DNA (mtDNA) have enabled precise base substitutions and the efficient elimination of…

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CellComM Lab
@cellcommlab.bsky.social

Mysterious increase in the motility of these #lysosomes After adding a non-stimuli treatment the lysosomes (cyan) got crazy (see color coded tracks) Maybe #mechanosignaling triggered by shear stress? #Microscopy + #Cells for #FluorescenceFriday 🧪🔬 #SciSky #scicomm #CellBio

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Heiko Lickert
@heikolickert.bsky.social

Thrilled to share one of our biggest discoveries: “Inceptor binds to and directs insulin towards lysosomal degradation in beta cells”. doi.org/10.1038/s422... A tremendous collaborative effort led by JohannaSiehler, Sara Bilekova and other members of the Lickert lab @heikolickert.bsky.social

doi.orgInceptor binds to and directs insulin towards lysosomal degradation in β cells - Nature MetabolismThe insulin inhibitory receptor (inceptor) is found to bind to insulin and to regulate insulin stores by directing proinsulin and insulin towards lysosomal degradation.

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bioRxiv Genetics
@biorxiv-genetic.bsky.social

Tissue-specific responses to TFAM and mtDNA copy number manipulation in prematurely ageing mice https://www.biorxiv.org/content/10.1101/2024.11.14.623694v1

biorxiv.orgTissue-specific responses to TFAM and mtDNA copy number manipulation in prematurely ageing mice https://www.biorxiv.org/content/10.1101/2024.11.14.623694v1 Somatic mitochondrial DNA (mtDNA) mutations are heavily implicated as important drivers of ageing an

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Jonathan Friedman
@labfriedman.bsky.social

Happy to have my first post on this site be to share the news that our amazing student Alia will be presenting her work on mitochondrial fission at MitoChats Thursday (10am US central time)! Be sure to check it out!

Ewa Bomba-Warczak@ebomba.bsky.social

MITOtalks have not made it here (yet) but we are excited to host two fantastic trainee talks this week on MITOchats - Alia Edington from Friedman lab at UTSW and David Eberhardt from Chaudhuri at UUtah - visit www.mitotalks.org for more info and zoom link to join! #mitochondria please share!

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Anne Carpenter
@drannecarpenter.bsky.social

I can’t even fathom how clueless a person would need to be to say this out loud. Open any history book, any corporate lawsuit and see how far you can trust humans in the face of greed. And *especially* institutions where people are “just doing their job”.

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