RSC Chemical Biology

✨ Don't miss this Advance Article from Jack Jeffries and team on the biocatalytic potential of wild-type split transketolases! ➡️ Find out more about this promising class of carboligases here: doi.org/10.1039/d6cb... #RSCChemBio #Biocatalysis

✨ Have you read Anna Vagstad's contribution to our 2026 Emerging Investigator's collection? ➡️ Anna presents a promiscuous enzymatic system to rationally produce diverse lipopeptides using enzymes from the kamptornamide RiPP natural product pathway! 🔓 Find it here: doi.org/10.1039/d6cb...

☀️ Happy Friday! ☀️ 🧪 Don't miss out on Jie Wang and team's newest manuscript featuring a genetically encoded custom “photostabilizer” amino acid to improve the ability of fluorescent proteins to resist photobleaching! ✨ Read it here doi.org/10.1039/d6cb...

📢 HOT article alert! 📢 🔥 Read Robert J Brea and team's review on bioorthogonal chemistry for deciphering lipid biology in living systems out now in #RSCChemicalBiology! ➡️ Find it here doi.org/10.1039/d6cb...

On my way to ICBS 2026 for @rscchembio.rsc.org! Looking forward to meeting everyone this week in San Francisco.

Our latest newsletter is now online! Read it on our blog at the link below, and sign up to get our newsletters straight to your inbox at https://rsc.li/alerts blogs.rsc.org/cb/202...

📢 Issue 10 of RSC Chemical Biology is out now and #OpenAccess! Read work on intrinsically disordered transcription factors, expanding the E3 ligase toolbox for PROTACs, molecular glues, RNA binding proteins, antisense oligonucleotides and more! 👉 pubs.rsc.org/cb/issue/7/10 #RSCChemBio

We're pleased to share the winner of the best poster award sponsored by RSC Chem. Biol. at the 22nd Annual Tri-institutional Chemical Biology Symposium is Theodore Yassa, for “Protein-Protein Interaction Discovery in Human Solid Cancer Biopsies”. Please join us in congratulating the winner!

📢 Don't miss out! There are only two weeks left to register is for the inaugural Valrose Chemical Biology Exchange 2026 in Nice, France! 📅 23 October 2026 Find out more valcbx2026.wordpress... Registration here valcbx2026.wordpress... #ValCBX2026

🏅 Meet one of our 2026 Emerging Investigators! ✨ Lianne Willems develops glycotools to study ribitol phosphate biology! Her latest study, now out in #RSCChemBio, reveals a new enzyme cascade that breaks down barriers in the synthesis of much-needed CDP conjugates. 🔓doi.org/10.1039/d6cb...

🔥 Don't miss #RSCChemBio Advisory Board member, Luc Brunsveld's, newest manuscript! ✨ Read their report on the stabilisation of Tau/14-3-3 protein-protein interactions using reversible-covalent small-molecule molecular glues! 👉 doi.org/10.1039/d6cb...

✨ Want to know more about RNA modifications and RNA-binding proteins? #RSCChemBio have the manuscript for you! ➡️ Amanda Garner and team present their review on RNA mods and RBPs looking at interactions, regulation and avenues for therapeutic modulation! 👉 doi.org/10.1039/d6cb...

🔥 Have you read the newest manuscript from Emerging Investigator Sarah Keane? ➡️ Find their work "Use of conformationally locking antisense oligonucleotides for the targeted inhibition of precursor microRNAs" out now in #RSCChemBio 👉 doi.org/10.1039/d6cb...

📢 New RSC Chemical Biology manuscript alert! 📢 ✨ Read Ruth Nussinov and her team's newest review deciphering the structural “why” behind the specific kinase order in cascades as the key design principle of cellular signalling! ➡️ Read it here doi.org/10.1039/d6cb...

Early registration and abstract submission for ICBS 2026 close very soon on 30 September! Don't miss your chance to participate in this year's meeting, which includes trainee communication awards sponsored by RSC Chemical Biology. www.chemical-biology.org/page/ICBS2026

📢 Issue 9 of #RSCChemBio is out now! ✨ Read about cyclic pentapeptides inhibiting protein kinase CK2, strategies for activating silent or weakly expressed fungal BGCs, a G-quadraplex binder that selectively downregulates c-MYC expression and much more! pubs.rsc.org/cb/issu... #OpenAccess

☀️ Happy Friday! Have you read Dmitri Filippov and Edward Emmott's newest communication on the newest molecular tool to study norovirus replication? ➡️Find it here! doi.org/10.1039/d6cb... #RSCChemBio #VPgPeptide

📢 Don't miss Jack Rowbotham and his team's contribution to our newest Biocatalysis themed collection! ✨ In their newest manuscript: find the discovery and engineering of a new (R)-selective transaminase from Capronia coronata for production of sitagliptin! ➡️ doi.org/10.1039/d6cb...

We're delighted to announce that Alice Eddershaw, Karolinska Institute, Sweden has won our best poster prize at the #GP2A2026 conference! Please join us in congratulating Alice, whose winning poster was "Small-molecule chemical switches change the function of the repair protein HMCES".

📢 Registration is now open for the inaugural Valrose Chemical Biology Exchange 2026 in Nice, France featuring researchers across chemical biology, genetic code expansion and protein engineering! 📅 23 October 2026 Find out more valcbx2026.wordpress... Registration here valcbx2026.wordpress...

☀️ Happy Tuesday! Have you read this Advance Article from Thomas Kodadek and his team out now in #RSCChemBio? ➡️ Find a new strategy for the fragment-based discovery of low molecular weight protein targets using FOLDON! ✨ Read more here: doi.org/10.1039/d6cb...

📢 It is less than a month to go to the 10th RSC BMCS Fragment-based Drug Discovery Meeting happening from 14-16th September in Cambridge at Churchill College, University of Cambridge! #Fragments2026 ➡️ Find out more here! lnkd.in/eQxkutFh 👉 Register here! lnkd.in/eHJ34vky

✨ Have you read this Advance Article out now in #RSCChemBio? ➡️ Junji Kawakami present their newest manuscript on the screening of functional nucleic acids with low pH cleavage activity! 👉 Find it here doi.org/10.1039/d6cb...

📢 Out now in #RSCChemBio! 🧪 Danielle Schmitt and her team present iGlo: the newest protein-based optical reporter for the sensitive and precise study of compartmentalized glutamine dynamics! ✨ Read more here: doi.org/10.1039/d6cb...

Our new collection on Chemical Glycobiology is now online! This collection highlights the use of innovative chemistry in advancing glycobiology. We are excited to share these contributions that feature all aspects of a field that truly tackles the sweet side of biology! blogs.rsc.org/cb/cbg...

Nominations are now open for the ChemComm Emerging Investigator Lectureship, recognising an outstanding independent early-career researcher who is advancing the chemical sciences through their exceptional research. Anyone can nominate – make yours today www.rsc.org/standards-an...

We are delighted to sponsor the ICBS' trainee communication and poster awards at the upcoming ICBS 2026 conference in San Francisco! Abstract submission closes at the end of this week, and registration on Sept 30. Don't miss your chance to participate! www.chemical-biology.org/page/ICBS2026

📢 Now out in #RSCChemBio! ✨ Anna Barnard and her team present their affinity-based protein profiling of three classes of α-helix mimetics revealing significant differences in proteome-wide selectivity. ➡️ Read it here: http://doi.org/10.10...

📢Issue 8 of RSC Chemical Biology is out now and #OpenAccess! Find our outstanding reviewers editorial as well as articles on antibiotic symmetry, G4-G4 ligand aggregates, DNA origami-based drug delivery, coiled coil peptides as PPI inhibitors and more! 🔗 pubs.rsc.org/cb/issu... #RSCChemBio

RSC Chem. Bio, @chemicalscience.rsc.org and @orgbiomolchem.rsc.org are sponsoring awards at the 22nd (25th anniversary!) Tri-I Chemical Biology Symposium, September 16 at The Rockefeller University. Find out more about the meeting and register for free: chembio.triiprograms.org/publications...

🐜 Fungus-growing ant species make a host defence peptide (abaecin-2) with a copper-binding effect that is either inhibitory or protective! ➡️ Read more about these dual roles of this HDP in the newest publication out now in #RSCChemBio 👉 http://doi.org/10.10... #HDP

We’re excited to announce the 22nd International Conference on Biological Inorganic Chemistry (ICBIC22). Join award-winning speakers for plenary, keynote, invited & contributed talks, submit to our poster session & join a full social programme with your community: https://www.icbic2027.org #ChemSky

📢 Don't miss this Communication from Shuo Han and his team introducing NovaID: a HyperNova-based compact and versatile proximity labeling platform! ➡️ Read more here: doi.org/10.1039/d6cb... 👏 Shuo Han is one of our 2026 Emerging Investigators... Stay tuned to hear more!

RSC Chemical Biology is delighted to be partnering with the #SBNP conference. The final deadline is closing on Tuesday 11th August 2026. If your considering joining the conference register now. Click here for more information: https://bit.ly/4bHu5Q7

📢 Don't miss your chance to register for the 10th RSC BMCS Fragment-based Drug Discovery Meeting happening from 14-16th September in Cambridge at Churchill College, University of Cambridge! #Fragments2026 ➡️ Find out more and register here! www.rscbmcs.org/even... www.eventsforce.net/...

There is less than one month left to submit your poster abstract for this year's Chemical Science symposium! Abstract submission closes on 20th August - we hope to see you in October for two days of talks and discussions on digital chemistry! Further information here: rsc.li/chemscisymp2026

🔥 Don't miss this HOT review from #RSCChemBio on mechanism-based HDAC inhibitors! ➡️ Read the article by David Christianson here! doi.org/10.1039/d6cb... #EnzymeInhibition

Catch up on the latest news from RSC Chemical Biology in the journal newsletter, available on our blog at the link below. Signing up to receive new issues by email at rsc.li/alerts blogs.rsc.org/cb/july-2026...

We're pleased to share that Professor Boris Vauzeilles has joined our Editorial Board as an Associate Editor. Prof. Vauzeilles is a CNRS Research Director and Director of the Institut de Chimie des Substances Naturelles (ICSN, CNRS, France). Find out more on our web page: www.rsc.org/people/boris...

✨ "The VanVeller lab is exploring amidine peptide-backbone modifications. By replacing the native amide with an amidine they directly alter a key site of protease recognition while preserving side-chains necessary for activity at opioid receptor GPCRs." ➡️ doi.org/10.1039/d6cb...

📢Issue 7 of RSC Chemical Biology is now online and #OpenAccess ✨ Find articles on peptidomimetic GABRAP ligands, artificial nicotinamide cofactors, chlorophyll biosynthetic enzymes and much more! ➡️ Read it here: pubs.rsc.org/cb/issu...

📢 Don't miss Toru Komatsu and Yasuteru Urano's newest review in #RSCChemBio where they 'revisit the past to discover the new.' ✨ Their review explores how a century of classical chemistry continues to inspire modern enzyme-responsive fluorescent probes. Read it here: doi.org/10.1039/d6cb...

➡️ Have you seen this #RSCChemBio Advance Article out now from our newest themed collection on Biocatalysis? 🍄‍🟫Read Gideon Grogan, Will Unsworth and their team's report on the newest family I unspecific peroxygenase from Daldinia childiae: DchUPO! ✨ http://doi.org/10.10...

📢 Have you read this review from Frank Gunn-Moore FRSB FRSE and his team at the University of St Andrews? ✨ Find their evaluation of 17β-HSD10 inhibition towards developing therapies for Alzheimer's disease out now in #RSCChemBio! ➡️ Read it here: http://doi.org/10.10...

We're pleased to announce that PhD candidate Vanessa Rogga of the Tate laboratory at Imperial College London is the winner of our best poster award at this year's Gordon Research Conferences meeting on Induced Proximity! Please join us in congratulating Vanessa. www.grc.org/induced-prox...

🌿 From Christopher Neil Hunter The University of Sheffield, find the newest #RSCChemBio Perspective on chlorophyll! ➡️ Read their extensive review looking at everything Chl biosynthesis including new structural insights using AlphaFold! ✨ http://doi.org/10.10...

☀️ Happy Friday! ☀️ ➡️ Have you read George Lisi and his team's work on how the GM-CSF histidine triad toggles its structure for physiological and pathological interactions yet? ✨ Find it out now in #RSCChemBio 👉 http://doi.org/10.10...

📢 Call for Abstracts is OPEN! 📢 Join the GEM-APPICOM Joint Meeting in Lyon (Nov 3–6, 2026) for "At the Confluence of Biomembrane Sciences." 🧬🔬 From membrane proteins to computational biophysics—we want your research! ⏳ Deadline: July 1 🔗 gem-2026.sciencescon... #GEM2026 #Biophysics #Science

📢 Welcome to Issue 6 of #RSCChemBio! Read our cover articles using hybrid computational-experimental approach to probe acyl-carrier protein sequence diversity and RNA-amiloride binding respectively! doi.org/10.1039/D5CB... doi.org/10.1039/D6CB... ➡️Find the issue here! pubs.rsc.org/en/jour...

Meet one of our 2026 Emerging Investigators! Sascha Hoogendoorn is tipping the balance towards PLK4 degradation at centrioles with their newest manuscript in #RSCChemBio! Catch the manuscript here: http://doi.org/10.10... #PLK4