Sonja Schmid

Glad to present #Nanophotonic DyeCycling – #BenjaminVermer’s magnum opus! 🎉 By breaking the longstanding photobleaching limitation in single-molecule #FRET, we achieve longterm observations of conformational #dynamics – gaining >1 order of magnitude more info. www.biorxiv.org/content/10.6...

nanoscience.unibas.chnanoscience.unibas.ch

🧑‍🎓 Calling aspiring #PhD students: Now is a good time to apply to the PhD school of the @nanoscience.ch @unibas.ch Switzerland: #Nanopore detection of metal- #nanocluster heterogeneity with single-molecule resolution. nanoscience.unibas.ch/fileadmin/us...

nanoscience.unibas.chPhD program | Swiss Nanoscience Institute | University of Basel

More info: nanoscience.unibas.ch/en/forschung... And the application submission system: biped.sni.unibas.ch/application/... Please don't apply by email. Thank you.

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Right in time for #smFRET’s 30th anniversary, DyeCycling enables true single-molecule kinetic analysis, revealing hidden heterogeneities and even time-variant kinetic changes of individual molecules.

My thanks for this inter-disciplinary collaboration go to all co-authors, all who commented and contributed in different ways, and the @nanoscience.ch for their support. 🙏

Swiss Nanoscience Institute, University of Basel

The trick is to harness reversibly binding fluorescent probes – and their cumulative photon budgets – rather than single dyes whose bleaching terminates the observation immediately. High SNR is retained through efficient nanophotonic background suppression, demonstrated using DNA & protein systems.

Sonja Schmid reposted

@nanoscience.ch

15 July

🏊‍♀️💦Need to cool off? No problem with July’s “Tool of the Month": The swim bag. It holds a lot and everything stays dry when you jump into the Rhine after work or studying (don't forget to follow security advices). nanoscience.unibas.ch/en/news/deta... @unibas.ch @baselstadt.bsky.social #nanoscience

nanoscience.unibas.chTool of the Month: The Swim Bag – Perfect for Basel’s Summer!

Sonja Schmid reposted

GdR ImaBio 🔬

@gdrimabio.bsky.social

16 June

Replying to @gdrimabio.bsky.social

👏 Un grand merci à tou·te·s les intervenant·e·s pour leurs contributions inspirantes, notamment les conférenciers : @broichhagenj.bsky.social @fmp-berlin.de @glembockyte.bsky.social @mpi-mr.bsky.social Pablo Rivera Fuentes @chem.uzh.ch @scisonja.bsky.social @unibas.ch

Sonja Schmid reposted

IDPSeminars

@idpseminars.bsky.social

6 May

IDPSeminars is back TOMORROW (Thursday May 7th)! Come see Matt Parker and Maria Hondele speak! 1 pm EST / 7 pm EU - sign up with the link from our homepage idpseminars.com

grc.org2026 Single Molecule Approaches to Biology (GRS) Seminar GRCThe 2026 Gordon Research Seminar on Single Molecule Approaches to Biology (GRS) will be held in Les Diablerets, Vaud (fr) Switzerland. Apply today to reserve your spot.

20 Apr

PhD's & postdocs: dont miss the GRS partner conference, organized by @qmsmith.bsky.social & #AlbaGómez-Segalàs with lots of interaction opportunities and career mentorship: ⏰ June 27-28, 2026 🌍 Swiss Alpes (✈️ Geneva) ✅ APPLY now: deadline May 30. www.grc.org/single-molec...

Sonja Schmid@scisonja.bsky.social

Don't miss the #GordonConference on 𝑺𝒊𝒏𝒈𝒍𝒆-𝒎𝒐𝒍𝒆𝒄𝒖𝒍𝒆 𝑨𝒑𝒑𝒓𝒐𝒂𝒄𝒉𝒆𝒔 𝒕𝒐 𝑩𝒊𝒐𝒍𝒐𝒈𝒚, organized by #KevinWelsher & me: ⏰ June 28 - July 3, 2026 🌍 in the Swiss Alpes (✈️ Geneva) ✅ APPLY now: deadline May 31. We're 75% booked: register today & be there! 🙌 🕳️ 🧬🧪🧫 🔬🟩🟥🟩🟥🏋️‍♀️💥🪤 🍩 ... you get it... 😁

20 Apr

grc.org2026 Single Molecule Approaches to Biology Conference GRCThe 2026 Gordon Research Conference on Single Molecule Approaches to Biology will be held in Les Diablerets, Vaud (fr) Switzerland. Apply today to reserve your spot.

20 Apr

We're super excited about the speaker line-up at this GRC, featuring e.g. keynotes from @melikel.bsky.social, #ShuoHuang, #ScottBlanchard, @ceesdekker.bsky.social – and more talk slots are still available! www.grc.org/single-molec...

Sonja Schmid reposted

RCSB Protein Data Bank

@rcsbpdb.bsky.social

8 Apr

Download a Protein Domains Poster from PDB-101 This poster highlights common arrangements of secondary structure elements in protein domains as defined by CATH.

pdb101.rcsb.orgPDB101: Learn: Flyers, Posters, & Calendars: Posters: Folding of Protein DomainsThis poster highlights common arrangements of secondary structure elements in protein domains as defined using the CATH classification scheme.

19 Mar

Don't miss! 👇

Quentin Smith@qmsmith.bsky.social

🚨 3 DAYS remaining until the Abstract Deadline on 22nd March 2026! 🔬 We’re calling all early career researchers to apply as soon as possible to be considered for an oral presentation! 🔗 www.grc.org/single-molec... #biology #biophysics #single-molecule #microscopy #ECR

schmid.chemie.unibas.chJoin us! | Research Group Schmid | University of Basel

10 Mar

Last call for these 2 different #PhD positions in #nanopore tech: 🗓️ apply by March 15 to join our team at the nano-dynamics group at @unibas.ch Switzerland. Follow the guidelines online: schmid.chemie.unibas.ch/en/join-us-1/

This post is unavailable.

Sonja Schmid reposted

meisterlab.bsky.social

@meisterlab.bsky.social

4 Mar

Exciting news: Our RNA community in @uniregensburg.bsky.social is set to grow! We are opening a Junior Group Leader position in RNA biochemistry / ribonucleases / RNA stability. A great opportunity to start your own team within our collaborative RNA network. Details & application 👇

Sonja Schmid reposted

meisterlab.bsky.social

@meisterlab.bsky.social

4 Mar

Replying to @meisterlab.bsky.social

karriere.uni-regensburg.de/jobposting/2...

Sonja Schmid reposted

Johannes Hohlbein

@hohlbeinlab.bsky.social

26 Feb

Coordinated call for applications for three (!) thematically related professorships (cell physiology, molecular genetics, and biochemistry) at BTU Cottbus-Senftenberg (Germany) (thread)

bluesky-map.theo.ioBluesky MapInteractive map of 3.4 million Bluesky users, visualised by their follower pattern.

Where are you on the blueSky-map? bluesky-map.theo.io

Theo Sanderson@theo.io

I made a map of 3.4 million Bluesky users - see if you can find yourself! bluesky-map.theo.io I've seen some similar projects, but IMO this seems to better capture some of the fine-grained detail

Sonja Schmid reposted

Karolin Luger

@nucleosomepolice.bsky.social

#scientists, take a second to fully appreciate the @pdbeurope.bsky.social and @rcsbpdb.bsky.social and imagine live without them.

Protein Data Bank in Europe (PDBe)@pdbeurope.bsky.social

By 2028, all 4-character PDB IDs will be exhausted. After that, all new entries will receive extended IDs: 12 characters total, formatted as pdb_ + 8 alphanumeric characters (pdb_1000axyz) Test it from PDB Beta Archive Read more: www.wwpdb.org/news/news?ye...

What a unique experience to lecture at #SeniorenUni @unibas.ch today – freely translated title: Molecules in gallop – getting 'personal' with the molecules of life. We filled the big aula 2x with 55+ers up to >80y-olds plus 100more online! All of them so genuinely curious! Truly touching! 🤝...

...people hugely differing in age, backgrounds, education... A real challenge for me, but how eager they were to learn & how #grateful! Heartwarming to hear the metaphors (🍝,🍯,🐎,📻 for #FRET, 🐘&🐜 for #nanopores,...) helped them to understand, and even inspired them to think further. We discussed...

science.orgFrom sequence to function: Bridging single-molecule kinetics and molecular diversityBiological function is fundamentally determined by nucleic acid and protein sequence. Beyond encoding genetic information, nucleic acids also display complex physicochemical parameters that shape stru...

...the molecules of life, how they feel in the cell, up to #single-molecule exp. & apps... Questions were also exciting😅 from: "how can you truly get single molecules?" to: "what metaphysical thoughts do you have?" All genuine questions. #sciComm – so rewarding – didnt expect that! 🤝 Thank you!

Sonja Schmid reposted

Achilles Kapanidis

@achilleskap.bsky.social

30 Jan

Great to see our Science Review on emerging multiplexed single-molecule methods that use libraries to link sequence to dynamics. A fun collaborative writing project! From sequence to function: Bridging single-molecule kinetics and molecular diversity | Science www.science.org/doi/10.1126/...

1 Feb

Unheard of. @msf.ca #DoctorsWithoutBorders

Al Jazeera English@aljazeera.com

Israel says it will ban MSF from operating in Gaza https://aje.news/13btyf

1 Feb

We had a little celebration last week. 😊 #Already5y ...time flies!

Swiss National Science Foundation (SNSF)

12 Jan

Good morning #FRET friends, Good news: #FRET is on track!

Sonja Schmid reposted

@snsf.ch

18 Dec 2025

The SNSF is considering restrictions for its Project funding. Goal: to ensure the quality of evaluation & stable success rates despite an increasing number of applications and limited funding. The final decision will be made in January 2026. 👉 buff.ly/iGOCf7R #research #science

buff.lyProject funding restrictions envisagedThe SNSF is responding to increased demand from researchers in order to ensure evaluation quality and stabilise success rates.

16 Dec 2025

Travelling back from #Paris 🚄, where #EllynRedheuil defended her PhD at @espciparispsl.bsky.social. Inspired by our #DyeCycling approach, Ellyn did impressive pioneer's work on single-biomarker detection using @quantum-si.bsky.social's protein sequencing platform!

Sonja Schmid reposted

Al Jazeera English

@aljazeera.com

12 Dec 2025

Israel approves 19 new West Bank settlements in major annexation push https://aje.io/7xi4oe

12 Dec 2025

Thrilled to announce the successful import of the Dutch🇳🇱 Santa Claus tradition into Switzerland🇨🇭: So much fun with this creative team! 🎅😃 Sad to see team members leave – but also happy to welcome new ones: Bye Ben & David! Welcome Bastien, Antonella & Julius!!

11 Dec 2025

@dpgphysik.bsky.social are you kidding me? 😃 ...and the list goes on...🎓

der-postillon.comDamit man sich für "Merci" revanchieren kann: Storck bringt "De rien"-Schokolade auf den MarktBerlin (dpo) - Endlich kann man angemessen reagieren, wenn man "Merci"-Schokolade geschenkt bekommt. Der Süßwarenhersteller Storck bringt knapp 80 Jah

2 Dec 2025

😅

Der Postillon 📯@der-postillon.com

Damit man sich für "Merci" revanchieren kann: Storck bringt "De rien"-Schokolade auf den Markt www.der-postillon.com/2023/12/de-r...

unibas.chSeven honorary doctorates and one honorary councillor at the University of Basel’s Dies academicus 2025At the Dies academicus 2025, the University of Basel honored leading figures from the fields of art, science and society. In addition to awarding seven honorary doctorates and numerous prizes, an hono...

29 Nov 2025

My 1st #DiesAcademicus at @unibas.ch – once per year 🎓gowns, flags, colours & speeches, and about the biggest banquet I've ever seen. www.unibas.ch/en/News-Even...

29 Nov 2025

...bonus points if you find me on the pic 😉

25 Nov 2025

Lower success rate in each case in 🇨🇭 compared to 🇪🇺:

Swiss National Science Foundation (SNSF)@snsf.ch

How did the SNSF's transitional measures differ from European calls? Our most recent #DataStory shows that researchers in Switzerland submitted more applications to the SNSF than they had previously to European calls for proposals. 👉 sohub.io/z9hz

bit.lyItaly probes Sarajevo ‘sniper safaris’: What were they, who was involved?According to a lawsuit, participants would be flown from Italy to Bosnia where they would pay to shoot people.

13 Nov 2025

What??

Al Jazeera English@aljazeera.com

According to a lawsuit, participants would be flown from Italy to Bosnia where they would pay to shoot people.

Sonja Schmid reposted

Life Sciences Switzerland (LS2)

@lifesciswitzerland.bsky.social

12 Nov 2025

🚨 Last week to submit your abstract! LS2 Annual Meeting 2026: 📍 Zürich | 🗓 Feb 11–12 (YSS: Feb 10) Join us for keynotes by Sarah-Maria Fendt, Heidi McBride & Jennifer Lippincott-Schwartz + 11 symposia, poster session, & networking. 🔗 Abstracts due Nov 16: annual-meeting.ls2.ch/2026/registr...

marie-sklodowska-curie-actions.ec.europa.euPostdoctoral FellowshipsThe information provided on this page is a summary of the main rules and requirements for Postdoctoral Fellowships (PFs) and who can apply for them.

11 Nov 2025

Join us for a #postdoc through a #MarieCurie fellowship via the 2026 call. Eligible candidates are invited to reach out with a tentative project idea. Happy to support you! marie-sklodowska-curie-actions.ec.europa.eu/actions/post...?

Ursula von der Leyen@vonderleyen.ec.europa.eu

Switzerland is joining Horizon Europe! We are uniting two research powerhouses. For cutting-edge innovation that will boost our energy security, digital transformation, health and so much more. Today is a good day for science, and for our EU-Switzerland partnership.

10 Nov 2025

I recently wrote a 1page "Highlight" article for the Swiss Journal @chimiajournal.bsky.social about the #single-molecule perspective on biomolecular dynamics and experiments: Beyond 3D Structures: New Ways to Study Biomolecular Gymnastics www.chimia.ch/chimia/artic...

7 Nov 2025

Early rise for me today (3:45 😱) to get in time to our #Nanopore consortium meeting with #GiovanniMaglia & @ceesdekker.bsky.social groups at Amsterdam airport. So curious about their newest results! 🤩 We approached in style: ✈️ flying over Dutch (modern) windmills... Beautiful – even for train fans.

7 Nov 2025

...and back to NL & Dutch language – stills feels very home-like 😊

2 Nov 2025

Single-molecule friends! The prelim. program of next year's sm- #Gordon conference in Switzerland is online: www.grc.org/single-molec... It'll be 3x fantastic: science, people, place in the alps ⛰️. Kevin & I hope to see you all next June: Have a look, tell your friends, and register!

24 Oct 2025

"If it needs to be fast..." says this lift ad... 🤭 Have a good weekend you all! seen at: www.srf.ch/static/cms/i...

24 Oct 2025

#Paris

Life Sciences Switzerland (LS2)

16 Oct 2025

Wow, @natnano.nature.com is down? 🤔

Sonja Schmid reposted

@lifesciswitzerland.bsky.social

16 Oct 2025

🚀 Got cool science to share? Join the Young Scientists’ Satellite in Zürich 🇨🇭 on Feb 10, 2026 to: *Talk about your research *Chat about AI & science comms *Win prizes & meet mentors ▶️ Find out more → annual-meeting.ls2.ch/2026/special...