Lucas Secchim Ribeiro

Lucas Secchim Ribeiro

@secchimribeiro.bsky.social

55 followers84 following28 posts

Lucas Secchim Ribeiro
@secchimribeiro.bsky.social

Warum die Risiken der Data Sharing eingehen, wenn Sie die Prinzipien des Data Visiting sicher umsetzen können? Besuchen Sie unsere Seite, um mehr über den COVID-19 Immuno Hub zu erfahren!

COVIM - NUM-Plattform für Immunitätsforschung@covim-platform.bsky.social

Daten quer durchs Land schicken? So letztes Jahrzehnt. 🧳 Beim COVIM ImmunoHub reist die Analyse zu den Daten – per Swarm Learning, ohne zentrale Datensammlung. Haken: Das klappt nur mit mit gleichen Datenstandards. Wie wir die hinkriegen: www.linkedin.com/posts/covim-...

linkedin.comCOVIM | COVIMWas wäre, wenn sich Immundaten aus vielen Standorten gemeinsam auswerten ließen – ohne sie an einem Ort zusammenzuführen? 🔐 Genau das macht der COVIM ImmunoHub, unterstützt vom DZNE, möglich. Statt ...
Lucas Secchim Ribeiro
@secchimribeiro.bsky.social

🚀 Entdeckt COVIM: Gemeinsam mit dem @dzne.science und dem @swarm-learning-hub.bsky.social die Forschung durch kollaboratives Lernen voranbringen!

COVIM - NUM-Plattform für Immunitätsforschung@covim-platform.bsky.social

Neue Förderperiode für COVIM: Aus dem Pandemieprojekt wird eine interdisziplinäre Immunitätsplattform im NUM und wir halten euch hier über aktuelle Entwicklungen auf dem Laufenden. 🔬 Mehr dazu auf unserer neuen Website: www.netzwerk-universitaetsmedizin.de/forschung/co... #Immunologie #NUM

netzwerk-universitaetsmedizin.deCOVIM | Netzwerk Universitätsmedizin
Lucas Secchim Ribeiro
@secchimribeiro.bsky.social

“‘The Secret Agent’ is a film about memory — or the lack of memory — and generational trauma. I think that if trauma can be passed along generations, values can too. So this is to the ones that are sticking with their values in difficult moments.” Words to follow and live by! Wagner Moura, BRAVO!

Lucas Secchim Ribeiro reposted

DZNE research center
@dzne.science

Congrats dear Lucas Ribeiro! Lucas has taken up a prestigious position in his home country of Brazil. Alongside his work at DZNE Bonn, the immunologist and bioinformatician is now a Visiting Research Fellow at his alma mater, the Federal University of Minas Gerais.

Lucas Secchim Ribeiro
@secchimribeiro.bsky.social

It was a pleasure to host the @sawitzkilab.bsky.social for the First Symposium on #SwarmLearning for Precision Medicine! Our team from the @dzne.science is always glad to engage with such outstanding researchers for important collaborations! Really excited with our plans for the future!

Sawitzki Lab@sawitzkilab.bsky.social

We’re excited to be a part of the Swarm Learning Initiative, working to accelerate immune response analyses in infectious diseases! Anika, Lev, and Birgit joined the 1st Swarm Learning Symposium at @dzne.science, where Anika shared innovative concepts for ex vivo functional analyses. 📈

Lucas Secchim Ribeiro
@secchimribeiro.bsky.social

Great example of how to make good use of #Olink and #SomaScan #proteomics in a population-level study! www.nature.com/articles/s41...

nature.comComparative studies of 2168 plasma proteins measured by two affinity-based platforms in 4000 Chinese adults - Nature CommunicationsMany recent proteomics studies use either Olink or SomaScan platforms to quantify proteins in high-throughput, but the consistency between the two is unclear. Here, the authors measure proteins in the...
Lucas Secchim Ribeiro
@secchimribeiro.bsky.social

Very interesting pre-print from the group of Vishva Dixit in California! The @genentech.bsky.social team found the small-molecule inhibitors of caspase activity can be delivered using GSDMD pores as an entry point! #Inflammasome #Immunology www.biorxiv.org/content/10.1...

biorxiv.orgDelivery of caspase inhibitors through GSDMD pores to inhibit pyroptosisCaspase-1, -4, -5, and -11 activate Gasdermin D (GSDMD) to form pores in the plasma membrane. In addition to releasing interleukin (IL)-1β and IL-18, GSDMD pores cause a lytic, proinflammatory form of...
Lucas Secchim Ribeiro
@secchimribeiro.bsky.social

Another fantastic shot from @roisinmcmanus.bsky.social at the mechanisms of activation and modulation of the #NLRP3 inflammasome! Congratulations to the McManus team at the @dzne.science and my dear friends at the iii @unibonn.bsky.social! Fantastic work! www.cell.com/immunity/ful...

cell.comNLRP3-mediated glutaminolysis controls microglial phagocytosis to promote Alzheimer’s disease progressionHow NLRP3 impacts Alzheimer’s disease (AD) is unclear. McManus et al. find that NLRP3 is located at mitochondria where it regulates microglial metabolism. Depletion or chronic pharmacological inhibiti...
Lucas Secchim Ribeiro
@secchimribeiro.bsky.social

As it turns out, Mars will not be kind to our immune system! Very interesting work from @dlr-spaceagency.bsky.social, @radboudumc.bsky.social and @unibonn.bsky.social! www.biorxiv.org/content/10.1...

biorxiv.orgImmune responses to human pathogens exposed to simulated Mars conditionsThe identification of health risks associated with long-term crewed missions to Mars is critical for mission planning and crew safety. Human-associated pathogens can be part of the microbiome and are ...
Lucas Secchim Ribeiro
@secchimribeiro.bsky.social

It has been a while since I worked with microbiome, but it is nice to see such as amazing effort out there! Great work on @cellpress.bsky.social by the group of @blekhman.bsky.social! www.cell.com/cell/fulltex...

cell.comIntegration of 168,000 samples reveals global patterns of the human gut microbiomeThe Human Microbiome Compendium is a unified database of publicly available human gut microbiome 16S samples, built with the integrated data from hundreds of independent projects. The compendium is us...
Lucas Secchim Ribeiro
@secchimribeiro.bsky.social

In this very interesting publication on @cp-immunity.bsky.social, Saller and the team of Olaf Gross unveiled the complexity of #NLRP3 activators, highlighting mitochondria’s roles in switching #apoptosis to NLRP3 #inflammasome activation! www.cell.com/immunity/ful...

cell.comAcute suppression of mitochondrial ATP production prevents apoptosis and provides an essential signal for NLRP3 inflammasome activationMitochondria control metabolism, cell death, and innate immunity, yet their reciprocal mechanistic connections are elusive, as is the conserved physiological function of the NLRP3 inflammasome. Saller...

Lucas Secchim Ribeiro reposted

CNN
@cnn.com

Fernanda Torres was a surprise win, taking home her first Golden Globe for best female actor in a drama motion picture for “I’m Still Here.” She told the red carpet ahead of the awards that she was the second Brazilian to be nominated, her mother Fernanda Montenegro being the first. cnn.it/3DIPxFO

Lucas Secchim Ribeiro
@secchimribeiro.bsky.social

Not only ASC specks and inflammatory cytokines, but gasdermin pores are found to be shared during pyroptosis! #Inflammasome #Immunology www.cell.com/cell/fulltex...

cell.comTransplantation of gasdermin pores by extracellular vesicles propagates pyroptosis to bystander cellsExpanding the consequences of pyroptosis, this study reveals that GSDMD pore-laden pyroptotic EVs transplant GSDMD pores on neighboring cell surfaces and propagate cell death to bystander cells.
Lucas Secchim Ribeiro
@secchimribeiro.bsky.social

The infamous article that stated the fallacious positive effect of hydroxychloroquine and azithromycin for COVID is now retracted, i.e., the results are made up and cannot be reproduced (of course). Let's hope that good science can prevail - faster - whenever needed the most.

You are up to date.