Jake Wintermute
Jake Wintermute
@synbio1.bsky.social
Synthetic Biologist - Foundry Theorist foundrytheory.substack.com stay humble biodesigners
1.8K followers428 following854 posts
Jake Wintermute reposted
Jake Wintermute reposted
Had a lot of fun making bioshrek and collaborative pixel art www.tiktok.com/t/ZP8gWSEdP/
Jake Wintermute reposted
Very proud of this work and all the efforts from my team and collaborators on this! You can now use DGRs for in vivo targeted hypermutagenesis in E. coli. We also included some early proof of concept in Yeast thanks to @seth-shipman.bsky.social !
🔈Paper out! We turned the most fascinating phage host-switch mechanism, diversity-generating retroelements, into a programmable mutagenesis tool, DGRec. You can perform targeted hypermutation of any 50-200bp sequence directly in vivo in E. coli www.nature.com/articles/s41...
Is there a “Plasmidsaurus for experimental data?” What is the fastest, cheapest way to start offering services that scientists want? To answer these questions, we have to build the CORE americanwetware.substack.com/p/build-the-...
16 years ago I blew off my thesis research for one day to make a YouTube video about plasmids www.youtube.com/watch?v=pNeC... Today I'm in the plasmid sequencing tutorials for Plasmidsaurus www.youtube.com/watch?v=pNeC... The trick to having a fun career in science is say yes to random fun things
Jake Wintermute reposted
The funniest version of the future is the one where we invent ASI only to watch it immediately start culturing brain cells to invent ASSI www.cell.com/cell-reports...
The good version of the future includes a decentralized bioeconomy supporting lots of good green-collar jobs in bioproducts and bioservices Sourdough microbakeries hint at what that future might look like www.nytimes.com/2026/01/26/d...