Tomás Di Domenico

Tomás Di Domenico

@tdido.eu

Director of IT and Scientific Computing at @cniostopcancer.bsky.social

49 followers111 following11 posts

Tomás Di Domenico
@tdido.eu

We're hiring a Systems Administrator (infra, storage and backup) at @cniostopcancer.bsky.social . Permanent contract, €45k to €65k, hybrid. www.cnio.es/empleo/syste...

cnio.esSystems Administrator (Infrastructure, Storage and Backup) for the IT, Scientific Computing and AI AreaDescripciónThe IT, Scientific Computing and AI Area at the Spanish National Cancer Research Centre (CNIO) is looking for a systems administrator to run the infrastructure behind the centre’s research ...
Tomás Di Domenico
@tdido.eu

We're hiring a Senior Scientific Computing Engineer at @cniostopcancer.bsky.social. Slurm HPC, GPU and AI infrastructure, research pipelines. €55k to €65k, four-year contract, hybrid. www.cnio.es/empleo/senio...

cnio.esSenior Scientific Computing Engineer for the IT, Scientific Computing and AI AreaDescripciónThe IT, Scientific Computing and AI Area at the Spanish National Cancer Research Centre (CNIO) is seeking a senior scientific computing engineer to take ownership of the infrastructure behi...

Tomás Di Domenico reposted

CNIO Bioinformatics Unit
@bioinformatics.cnio.es

🚀 Ya está abierto el plazo de preinscripción del 10º Máster en Bioinformática y Ciencias de Datos en Medicina Personalizada de Precisión y Salud. Formación teórico-práctica en programación, tecnologías multiómicas, IA y salud digital con datos reales. ℹ️ masterbioinformatica.com ¡Plazas limitadas!

Tomás Di Domenico reposted

Stephen Turner
@stephenturner.us

Démodé (2013) www.nature.com/articles/nph.... This short story imagines a future where AI systems designed to read and write scientific papers begin evolving on their own. At first, they help, running massive meta-analyses and accelerating discovery. Then they stop writing for us. 1/🧵

Tomás Di Domenico reposted

Glenn K. Lockwood
@glennklockwood.com

To be fair, this is how all the biggest AI infrastructure providers are bankrolling their growth: Google/Meta fund capex through their ads, Microsoft through Windows licenses. Now xAI has that sweet Starlink revenue. But I don't think Starlink has the margins that software/ads do.

Thorne 🌸 - Play Cozysters! 🎢@ens0.me

X financially unsustainable xAI buys it to bail it out xAI now financially unsustainable SpaceX buys it to bail it out 📍YOU ARE HERE SpaceX now financially unsustainable Tesla buys it out to bail it out

Tomás Di Domenico reposted

BSC-CNS
@bsc-cns.bsky.social

🌐Alfonso Valencia sobre la nueva función de #OpenAI con la que impulsa a sus usuarios a compartir su historia clínica con #ChatGPT: "Va a cometer errores, a generar malas interpretaciones y a poner al doctor en una posición complicada".

Tomás Di Domenico reposted

CNIO Bioinformatics Unit
@bioinformatics.cnio.es

📣 We are hiring a Postdoc in @bioinformatics.cnio.es at @cniostopcancer.bsky.social! 🔬 Cancer genomics, NGS, single-cell & spatial transcriptomics 💻 R/Bioconductor, Python, Linux HPC 🇬🇧 Fluent English 📩 Send your CV with Ref: AIPOSBIOINFCAM25II to empleo@cnio.es ℹ️ Full info: tinyurl.com/4hcskvtt

cnio.esPostdoctoral Research Assistant for the Bioinformatics UnitDescripciónThe Bioinformatics Unit within the Cancer Genomics programme is seeking to recruit a highly motivated and talented post-doctoral bioinformatician. The selected candidate will work in the co...

Tomás Di Domenico reposted

Champi
@jpascualanaya.bsky.social

🚨 We're hiring! 🚨 Our lab at the University of Málaga, Spain🇪🇸 is looking for a bioinformatician researcher for a postdoc position (1+1 years). Check the ad, and if you're interested, get in touch! 📅 Starting date early 2026, with some flexibility. 🙏Please, RT!

Tomás Di Domenico reposted

cniostopcancer.bsky.social
@cniostopcancer.bsky.social

La 'biología del big data' ya ajusta más las terapias a cada paciente.  300 especialistas han presentado sus últimos avances en las XV Jornadas de Bioinformática #JBI2025 (Madrid). Organizadores:  @bioinformatics.cnio.es, INB/ELIXIR-ES @cnb-csic.bsky.social y @biodata.pt 

bit.lyLa revolución de la bioinformática: descifrar el código de la vida para hacer realidad la medicina personalizadaEn biología, descubrir ya no es lo que era. La investigación húmeda, de microscopio y pipeta, ya casi no existe sin la de silicio: programas informáticos que extraen la información oculta en un mar de datos. Esta disciplina en auge, la bioinformática, es la que ayuda a entender qué hace cada variante genética, cada proteína: […]

Tomás Di Domenico reposted

EMBL-EBI
@ebi.embl.org

Replying to @ebi.embl.org

Learn more in the open access Nature Genetics paper: www.nature.com/articles/s41...

nature.comComplete genome assemblies of two mouse subspecies reveal structural diversity of telomeres and centromeres - Nature GeneticsTelomere-to-telomere assemblies of two mouse inbred strains, C57BL/6J and CAST/EiJ, offer improvements over the current mouse reference genome by adding telomere and centromere sequences that lead to ...

Tomás Di Domenico reposted

cniostopcancer.bsky.social
@cniostopcancer.bsky.social

Replying to @cniostopcancer.bsky.social

La Fundación Instituto Roche ofrece 4 becas de formación para cursar este máster. Suponen el 80% de la matrícula y este año las han conseguido David Dueñas, Jorge Santos, Mario López y Sofía Trigo.  ¡Enhorabuena! #CienciaDatosMPP #MPP

bit.lyEl máster que ha impulsado la bioinformática en España se enfoca en la medicina personalizada de precisiónTodos los avances médicos y de investigación de las últimas décadas se sustentan sobre una capacidad humana recientemente adquirida: extraer información valiosa de cantidades ingentes de datos. Es lo que hace la bioinformática, en sí misma un área de investigación cada vez más importante y que en los últimos años también crece de forma sinérgica […]

Tomás Di Domenico reposted

Roger Castells
@rcastellsg.bsky.social

We’re looking for an enthusiastic postdoc to join our team. 😊 The project focuses on protein design and cryo-EM applied to cancer research. 🔬🧪 The position is fully funded for 3 years. Please share 🙏 Job description and application details (deadline: October 11th): www.cnio.es/en/empleo/po...

cnio.esPostdoctoral Research Assistant for the Biomolecular Design and Structural Nanomedicine GroupDescriptionWe are looking for a Postdoctoral Researcher to join Roger Castells-Graells’ lab at the Spanish National Cancer Research Centre (CNIO). The successful candidate will work on innovative biom...

Tomás Di Domenico reposted

Andrej Spiridonov
@andrejpaleo.bsky.social

The grave risks for science as the whole of leaving fundamental scientific infrastructure in the hands of for-profit capitalist company. Essential scholarly services should be internationally curated by value-based societies/orders/colleges. 🧪

Hannah Shelley, MLIS (Maggots, Lycanthropes & Ice Skeletons)@hannahshelley.site

Since search is dead, how soon do you think Google Scholar is headed for the Google Graveyard? I'm betting it's soon, and academia is NOT prepared

hannahshelley.neocities.orgGoogle Scholar Is DoomedAcademia built entire careers on a free Google service with zero guarantees. What could go wrong?
Tomás Di Domenico
@tdido.eu

If you ever thought banking apps blocking you if you don't have a Google account was frustrating, imagine a world where the EU blocks you from accessing resources unless you accept Google's ToS... github.com/eu-digital-i...

github.comDo not add Google Play Integrity integration · Issue #10 · eu-digital-identity-wallet/av-app-android-wallet-uiIn the README, the following is listed: App and device verification based on Google Play Integrity API and Apple App Attestation I would like to strongly urge to abandon this plan. Requiring a depe...
Tomás Di Domenico
@tdido.eu

At @bioinformatics.cnio.es, we're looking for an HPC engineer to help us boost the scientific computing infrastructure at @cniostopcancer.bsky.social. Apply or get in touch for more details! www.cnio.es/empleo/advan...

cnio.esAdvanced Degree for the Bioinformatics UnitDescripciónThe Bioinformatics Unit within the Cancer Genomics programme is seeking to recruit a highly a highly motivated and talented High-Performance Computing (HPC) expert specialized in scientific...

Tomás Di Domenico reposted

Navin B. Ramakrishna
@navinbr.bsky.social

Glad to see this out, and to have contributed in a miniscule way to what will hopefully be an excellent resource: long read assemblies of 17 strains of mice www.biorxiv.org/content/10.1...

biorxiv.orgThe mouse pangenome reveals the structural complexity of the murine protein coding landscapeWe present the first mouse pangenome consisting of 17 high-quality inbred mouse strain genomes with complete annotation. This collection includes 12 widely used classical laboratory strains and 5 wild...
Tomás Di Domenico
@tdido.eu

I started experimenting with @nanoporetech.com long-read sequencing technology more than 10 years ago. A couple of years back it became my main focus, and we finally have our first results out: www.medrxiv.org/content/10.1...

medrxiv.orgMulti-Omic Profiling Reveals Epigenetic Drivers of Immunotherapy Resistance in Multiple MyelomaTargeted immunotherapies against B-cell maturation antigen (BCMA) have transformed the treatment landscape of Multiple Myeloma (MM). Fc receptor-like 5 (FCRL5) has emerged as an alternative target. Ho...
Tomás Di Domenico
@tdido.eu

When the first (promising) image-generating models appeared a few years ago I thought that maybe ~10 years later we'd be able to prompt our way into fixing the disaster that Episode IX was. I think my prediction may not be too far off.

Tomás Di Domenico
@tdido.eu

"We estimate the supply-side value of widely-used OSS is $4.15 billion, but that the demand-side value is much larger at $8.8 trillion. We find that firms would need to spend 3.5 times more on software than they currently do if OSS did not exist." simonwillison.net/2025/Mar/26/...

simonwillison.netA quote from Manuel Hoffmann, Frank Nagle, Yanuo ZhouWe estimate the supply-side value of widely-used OSS is $4.15 billion, but that the demand-side value is much larger at $8.8 trillion. We find that firms would need to spend …

Tomás Di Domenico reposted

Simon Willison
@simonwillison.net

Quick TIL: if you have uv installed and you want to try out ANY Python package in an ipython REPL, you can do so just by running uvx --with llm --with sqlite-utils ipython Pass as many --with package options as you like I wrapped it in a shell script, "itry llm" til.simonwillison.net/python/itry

til.simonwillison.netTrying out Python packages with ipython and uvxI figured out a really simple pattern for experimenting with new Python packages today:

Tomás Di Domenico reposted

Arvind Narayanan
@randomwalker.bsky.social

One of the biggest areas of AI hype right now is the notion that it will hyperaccelerate scientific progress. I understand why people think this — AI is already accelerating scientific _production_. 🧵

Tomás Di Domenico reposted

Simon Willison
@simonwillison.net

Replying to @simonwillison.net

If you have uv installed this means you can start chatting with a small model without first installing anything at all - this command will create an ephemeral virtual environment, install the necessary pieces and start a chat UI running in your terminal: uvx --with llm-smollm2 llm chat -m SmolLM2

You are up to date.