Theresia Gutmann

In vitro binding energies capture Klf4 occupancy across the human genome DNA binding energies for full-length Klf4, with its 400+ residues IDR! Sequence specificity sufficient to predict genome occupancy in human cells. www.pnas.org/doi/abs/10.1...

The deadline for the #GBM #Innovation #Award for young scientists was extended to 15 September 2026.

Recruitment for the EMBL International PhD Programme is officially open! 📣 At EMBL, we train young scientists to become skilled and creative future leaders in academia, industry and other sectors. Start your career in the life sciences with us! 🔎 Read more and apply here: bit.ly/4x9Edss

Registration is possible for the CellComm Summit / 29th STS Meeting. November 2-4 in Weimar! Application for Awards and grants is still possible.

1/5 How much phosphorylation can a single kinase deposit? In our new study with @typaslab.bsky.social out in @nature.com, phage T7's kinase (T7K) modifies almost all the E. coli proteome + more densely than all ~500 kinases do our own proteomes 🤯 www.nature.com/articles/s41...

Deadline is approaching - register soon!

Lipids build the membranes of all cells, but identifying their precise functions is extremely challenging. Here’s our attempt to change that: How to find and understand lipid-protein interactions, by Katelyn Cook & company. www.biorxiv.org/content/10.6...

Nachgefragt: Dr. Theresia Gutmann im Interview www.biospektrum.de/artikel/nach... @thegutmann.bsky.social Copyright rechter Bildteil: Katrin Boes (MPI-CBG)

The need for strong #ScientificSocieties has taken on a new urgency in the era of AI. It was a pleasure and an honor to deliver the #keynote lecture at the Polish Biochemical Society symposium on "New Perspectives in Biochemistry Research" at the Wrocław University of Science and Technology.

Had a fantastic EMBO|EMBL Symposium on "Cellular Mechanisms Driven by Phase Separation" and was delighted to present our perspective on biomolecular condensation in virus–host interactions. Congrats to our Predoc Silja Zedlitz @hymanlab.bsky.social on her poster prize! #2026PhaseSeparation @embl.org

As part of @sfb1638.bsky.social in 𝐌𝐞𝐦𝐛𝐫𝐚𝐧𝐞 𝐑𝐞𝐦𝐨𝐝𝐞𝐥𝐢𝐧𝐠, we are committed to developing computational tools that make complex membrane simulations more accessible, reproducible, and scalable for the scientific community. Today, we are happy to share the public release of 𝐎𝐩𝐞𝐧𝐌𝐞𝐦𝐛𝐫𝐚𝐧𝐞𝐁𝐮𝐢𝐥𝐝𝐞𝐫 v1.2.1

Safe to say that Day 1 of 'Cellular mechanisms driven by phase separation' has been a success so far, with lots of great talks, including a keynote by Karla Neugebauer, and plenty of opportunities to socialise and get to know each other 🙌🏼 #EESPhaseSeparation @embo.org @embl.org

Did you know that most of our conferences are in a hybrid format? Even if you are unable to travel, you have a few more days to register to attend #EESPhaseSeparation virtually! 🧬🦠🧪 • Access talks at your convenience • Ask questions • Network Register by 12 May: s.embl.org/ees26-08-bl

Anthony Hyman @embl.org & @mpi-cbg.de @hymanlab.bsky.social & Clifford Brangwynne @princetonupress.bsky.social & @hhmi-science.bsky.social receive their 2023 Breakthrough Prize at the Awards Ceremony in Santa Monica,LA, April 18, by Eileen Gu & @mrgatoasdf.bsky.social! www.mpi-cbg.de/news-outreac...

Cells are not just bags of molecules. Function depends on spatial interactions: RNAs and/or proteins come together with interaction partners to drive regulation and function. In our new preprint, we introduce ProPER, a novel method for in situ proximity detection. Preprint: tinyurl.com/muju86s6

Our work is finally out in Science Immunology ! This was an Amazing collaborative work from all co-authors, in particular the two co-first authors James Curson and Syeda Farhana Afroz . Never give up ! :) www.science.org/doi/10.1126/...

Excited to share our paper on the NLRP3 inflammasome condensate at the Microtubule Organizing Center (MTOC) by "precise!" cryo-electron tomography (cryo-ET), in collaboration with Jue (phyllis) Wang in the labs of Grant Jensen (BYU) and Pete Dahlberg (Stanford)! www.science.org/doi/10.1126/...

Design principles of human membrane protein topology https://www.biorxiv.org/content/10.64898/2026.04.18.719382v1

www.nature.com/articles/s41...

Lipid-CLEM by @mathilda95.bsky.social on the Cover of @natcellbio.nature.com! Link to article: www.nature.com/articles/s41...

A renaissance in targeting the PI3K/AKT/mTOR pathway www.nature.com/articles/s41... rdcu.be/faYxr This new Perspective discusses how advances in understanding of PI3K signalling in disease and novel pharmacological strategies are revitalizing interest in targeting the pathway

Welcome, Tony Hyman! EMBL welcomes its new Director General, Tony Hyman, as he takes up the mandate of leading EMBL's six sites. www.embl.org/news/embl-an...

Mosbach and the GBM are ready for you! 77. Mosbacher Kolloquium „More than lipidic barriers - new horizons in membrane biology“ #MK2026 #Mosbach

Have you registered yet? Early bird registration and abstract submission are open until January 31. mosbacher-kolloquium.org

Ein internationales Forschungsteam unter der Leitung von Prof. Dr. Konstanze F. Winklhofer, @ruhr-uni-bochum.de, hat einen entscheidenden Mechanismus der zellulären Müllabfuhr entschlüsselt. advanced.onlinelibrary.wiley.com/doi/10.1002/... Bild: Erstautorin Georgina Herrera, © RUB, Marquard

Congratulations to Julia Mahamid @embl.org on receiving the #LeibnizPrize 2026 for her pioneering work in in situ #structural #biology and for advancing our understanding of molecular architecture and cellular dynamics.

Here is a short video by @tudresden.bsky.social (in German) of me explaining what beta cells do and talking about our research on investigating the structural features of their function and dysfunction.

𝐂𝐨𝐧𝐠𝐫𝐚𝐭𝐮𝐥𝐚𝐭𝐢𝐨𝐧𝐬 𝐨𝐧 𝐫𝐞𝐜𝐞𝐢𝐯𝐢𝐧𝐠 𝐭𝐡𝐞 𝐒𝐓𝐒 𝐒𝐜𝐢𝐞𝐧𝐜𝐞 𝐀𝐰𝐚𝐫𝐝 2025! 🎉 At the 28th STS Meeting in Weimar Theresia Gutmann @thegutmann.bsky.social was honored with this award, which recognizes outstanding research by postdocs or junior PIs within the STS. Congratulations! @mpi-cbg.de #STS #CellCommSummit

Tony will become the next EMBL Director General! Congratulations, @hymanlab.bsky.social, exciting times ahead!

🎉 Hao Wu received the STS Honorary Medal for her lifetime contributions to uncovering molecular details of innate immune signaling. The laudatio by Theresia Gutmann highlighted her impact as scientist and mentor. Prof. Wu: your brilliance, dedication, and humor made this evening unforgettable ! 🌟

We had a good line up of speakers at the 50 years anniversary meeting of the german society of cell biology @dgz.bsky.social in Heidelberg. Tony gave the plenary, Koichiro talked about spatial control of P granules and Silja received a price for her Master thesis and gave a talk. Congratulations!

Congratulations to our PhD student David @rnadavid.bsky.social for his successful defense of his PhD thesis! @mpi-cbg.de imprs.mpi-cbg.de As you see the lab was very creative with his hat! David gave his insights on the nucleocapsid protein and even better arranged a great buffet for celebrations!

It was an honor to present the laudation for the 2025 STS Honorary Medal Awardee, Hao Wu (@harvardmed.bsky.social @bostonchildrens.bsky.social), at the 28th Signal Transduction Meeting. Her groundbreaking work has transformed our understanding of innate immune signaling. @sigtrans.bsky.social #STS

Das erwartet euch bei der letzten #Beerology2025: Ich spreche über das #Immunsystem und #Viren – Wissenschaft ohne Fachchinesisch, auf Deutsch! 📅 12. November 📍 Mondpalast, Dresden 🎟️ Eintritt frei! livesciencedresden.de #WissKomm #SciComm

Our PhD student Silja Zedlitz @hymanlab.bsky.social receives the #DGZ Master Thesis Award for her previous work!!! Looking forward to the meeting in Heidelberg and Silja's talk on "Minimal rhodamine probes for covalent protein labeling in live cells". Congrats to all awardees!

Abstract submission deadline for the #STS meeting on #SignalTransduction extended to 𝟯𝟬𝘁𝗵 𝗦𝗲𝗽𝘁𝗲𝗺𝗯𝗲𝗿. Great line-up of speakers with Hao Wu of Boston Children's Hospital delivering the #STS Honorary Medal: sigtrans.de/meeting-2025 | Weimar, 3-5 November

Dresden scientists @thegutmann.bsky.social and @rnadavid.bsky.social from the @hymanlab.bsky.social discover a new strategy used by the SARS-CoV-2 virus to hide from the body’s DNA immune detection system. Now published in @pnas.org. www.mpi-cbg.de/news-outreac...

How could SARS-COV-2 evade detection by host cells? Read the new paper from Theresia @thegutmann.bsky.social and David @rnadavid.bsky.social discussing how the nucleocapsid protein prevents recognition of the innate immunity sensor cGAS Congratulations!!! ‬