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If it's a repeat of the popular medieval plague (Yersinia pestis), it will be easily managed with modern antibiotics, assuming the Irkutsk region is Putin-friendly. If not, their people may want to get their affairs in order.

Yes, the old garden variety of plague is easily dealt with using modern antibiotics. As long as it has not been messed with in terms of its DNA.

Seems this plague lives naturally in this region in various animals, like squirrels that carry the bacteria andthe lab was studing the plague and doing research into ancient plague deaths in the region.

Some viruses that have been dormant for thousands of years are now reviving in the melting Siberian and Canadian arctic. 'Develop' those lands at your peril.