Adam Steinbrenner

Adam Steinbrenner

@adsteinbrenner.bsky.social

Associate Prof @UWBiology Seattle. How do plants recognize and resist pests ๐Ÿ›? We study receptor function + evolution in plant innate immunity. steinbrennerlab.org

1.2K followers348 following77 posts

Adam Steinbrenner reposted

Our transient expression system for diverse crops is now published in PLOS Biology! Check it out and see if we tested your favourite species... ๐ŸŒฑ doi.org/10.1371/jour...

doi.orgA broad-host-range Rhizobium rhizogenes strain enables transient expression across diverse crop speciesAgrobacterium-mediated transient expression has revolutionized plant research, but is largely confined to solanaceous species. This study shows that the engineered Rhizobium rhizogenes strain AS109 al...
Freddie King@freddie-king.bsky.social

Excited to share our preprint using Rhizobium rhizogenes AS109 for agroinfiltration, facilitating strong transient expression across non-model plants including sweet potato, mustard, Medicago and faba bean! doi.org/10.64898/202... 1/7

Adam Steinbrenner reposted

Our Special Issue on receptor-ligand interactions is now online! Thanks to all the authors for sharing their knowledge and views! Huge thanks to @adsteinbrenner.bsky.social @veroglez.bsky.social and @isabelmonte.bsky.social for great collaboration: ) @theplantjournal.bsky.social for the venue!

The Plant Journal@theplantjournal.bsky.social

๐๐ž๐ฐ ๐ฌ๐ฉ๐ž๐œ๐ข๐š๐ฅ ๐ข๐ฌ๐ฌ๐ฎ๐ž ๐‘๐„๐‚๐„๐๐“๐Ž๐‘-๐‹๐ˆ๐†๐€๐๐ƒ ๐ˆ๐๐“๐„๐‘๐€๐‚๐“๐ˆ๐Ž๐๐’ ๐ŸŒฑ Edited by @adsteinbrenner.bsky.social @veroglez.bsky.social @isabelmonte.bsky.social @elwirasmakowska.bsky.social ๐Ÿ“– Read the Editorial ๐Ÿ‘‰ doi.org/10.1111/tpj.71135 ๐Ÿ”Ž Explore the complete Special Issue ๐Ÿ‘‰ onlinelibrary.wiley.com/doi/toc/10.1...

Adam Steinbrenner reposted

Please share! Our lab at Colorado State University is recruiting a PhD student to join us starting fall 2027. We are broadly interested in plant molecular evolution and comparative genomics. More info about our lab and grad programs is available on our lab website. sites.google.com/site/danielb...

sites.google.comSloan LabWelcome! Our research focuses on the evolutionary process at the molecular level. In particular, we investigate how a mixture of natural selection and non-adaptive forces create and maintain the amazi...

Adam Steinbrenner reposted

Adam Steinbrenner reposted

Junior faculty position in Basic Sciences @fredhutch.org! Please repost!

Fred Hutch@fredhutch.org

๐Ÿ”ฌ Fred Hutch Cancer Center is hiring an Assistant or Associate Professor in the Basic Sciences Division @basicsci.fredhutch.org. Join a world-class research community in Seattle and help advance discoveries in fundamental biology. Apply: https://apply.interfolio.com/190640

Adam Steinbrenner reposted

We are deeply saddened to share that Michael Freeling passed away on 7/20/2026 after a year-long battle with cancer. Our deepest condolences go to his family, friends, colleagues, and the many students he inspired. We will share additional memorial information soon.

Now out in Science Advances. Inceptin Receptor helps attract predatory wasps in two years of field experiments. Next steps: can we tune both receptor recognition and volatile blend traits in crops + companion plants?

Adam Steinbrenner@adsteinbrenner.bsky.social

How do predatory wasps find their caterpillar prey? In our new preprint on Biorxiv we show that the host plant's immune system detects herbivory to sound the alarm. ๐ŸŒฑ๐Ÿ› See thread from @nataliagupa.bsky.social -- a surprising role for a plant PRR in indirect defense against herbivores.

We are excited to release the BAT!๐Ÿฆ‡๐Ÿšจ We've used this phylogenetic analysis pipeline in our lab for years, and grad Ben Sheppard now presents a Github release and preprint. I run BAT analyses almost daily. It makes exploring gene families routine, customizable, and fun๐Ÿงต

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We hope BAT will help molecular biologists to think in terms of gene trees. Evolutionary signal within gene families is often the first clue that there is amazing, novel biology to be found. Check out our repo and try out BAT analyses of YFGs (Your Favorite Genes!) github.com/steinbrenner...

github.comGitHub - steinbrennerlab/blast-align-tree: A pipeline to identify BLAST hits and perform phylogenetic analysis across multiple queries and local genome databasesA pipeline to identify BLAST hits and perform phylogenetic analysis across multiple queries and local genome databases - steinbrennerlab/blast-align-tree

We are excited to release the BAT!๐Ÿฆ‡๐Ÿšจ We've used this phylogenetic analysis pipeline in our lab for years, and grad Ben Sheppard now presents a Github release and preprint. I run BAT analyses almost daily. It makes exploring gene families routine, customizable, and fun๐Ÿงต

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Molecular biologists are especially interested in domains and motifs with known functions. BAT can highlight user-provided HMM profiles and amino acid motifs (via the ggtree R package) to visualize these features on a gene tree. Domain gain/loss is placed in evolutionary context.

Any labels or quantitative data (e.g. transcriptomic datasets) also integrate easily to the BAT pipeline. There is built-in FASTA header parsing ensures gene labels always match the dataset you are visualizing. For plant folks: we ship a subset of the Klepikova expression atlas.

We are excited to release the BAT!๐Ÿฆ‡๐Ÿšจ We've used this phylogenetic analysis pipeline in our lab for years, and grad Ben Sheppard now presents a Github release and preprint. I run BAT analyses almost daily. It makes exploring gene families routine, customizable, and fun๐Ÿงต

View full thread

BAT instead runs locally on any CDS or protein .fasta databases, even custom genomes with poor annotations. You can pip install blast-align-tree and fetch model organism genomes ๐Ÿง‘๐Ÿญ๐Ÿ€๐Ÿ’๐ŸŸ๐Ÿชฐ๐Ÿชฑ๐Ÿž It's easy to add any other new genome, just add the CDS or protein to /genomes folder.

As an example, immune receptor homologs often have complex evolutionary relationships collapsed by genome-wide orthogroup analyses. We show a BAT example for the NAIP family of mammalian NLRs, where mouse lineage-specific paralogs are known to have distinct recognition functions.

We are excited to release the BAT!๐Ÿฆ‡๐Ÿšจ We've used this phylogenetic analysis pipeline in our lab for years, and grad Ben Sheppard now presents a Github release and preprint. I run BAT analyses almost daily. It makes exploring gene families routine, customizable, and fun๐Ÿงต

BLAST-Align-Tree (BAT) does what it says on the tin: 1) finds homologs 2) aligns gene sequences 3) constructs a gene tree This is how you start any gene family analysis, but is still difficult to do from scratch or in genome portals. It's prohibitively hard in non-model species

This cherry blossom season is extra fun for us.๐ŸŒธ Students sequenced the genome of one of the iconic Yoshino cherry trees on the University of Washington quad, and found nearly identical clonal relatives in Japan! A great project with Alex Harkess and the American Campus Tree Genomes (ACTG) project

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This cherry blossom season is extra fun for us.๐ŸŒธ Students sequenced the genome of one of the iconic Yoshino cherry trees on the University of Washington quad, and found nearly identical clonal relatives in Japan! A great project with Alex Harkess and the American Campus Tree Genomes (ACTG) project

Our trees were moved to the UW quad in the 1960s from their original (1930s) arboretum location. But planting records haven't been found, so their origin is unknown. To investigate, we collected leaves of the northernmost tree outside Raitt hall and performed PacBio sequencing.

Adam Steinbrenner reposted

NSF GRFP applicants (and mentors): Was your application Returned Without Review and deemed ineligible despite fitting in the allowed topics? 1) Write NSF 2) Write your Congressperson 3) CC us at grfp@grant-witness.us so we can compile + follow up Details and template at grant-witness.us/grfp-letter

Adam Steinbrenner reposted

Adam Steinbrenner reposted

This position is still open. The Weisberg lab is recruiting a postdoc or Ph.D. student to study horizontal gene transfer in plant-associated microbial communities. Please see the job ad for more information and feel free to contact me if you have any questions!

Alexandra Weisberg@weisbergaj.bsky.social

The Weisberg Lab at Oregon State University is recruiting a postdoctoral scholar in molecular microbiology to study mobile genetic element host range and transmission in microbial communities. Please see the full job description here: files-dev.cqls.oregonstate.edu/Weisberg_Lab...

Adam Steinbrenner reposted

Adam Steinbrenner reposted

We (Nordborg & Weigel labs) need input on the next generation of genome browsers & data download modes for the #Arabidopsis #1001GenomesPlus project. We have now a curated collection of over 500 long read genomes. Please help us by filling out this questionnaire: docs.google.com/forms/d/e/1F...

docs.google.comNext generation of 1001 Genomes Plus browser and data downloadPlease indicate all features you would like to see in a browser that displays features of completely sequenced Arabidopsis thaliana genomes

Adam Steinbrenner reposted

A staggering statistic: "North American researchers were charged over US$2.27 billion by just two for-profit publishers. The Canadian research councils and the US National Science Foundation were allocated US$9.3 billion in that year." What are we doing?

Mark A. Hanson@hansonmark.bsky.social

We wrote the Strain on scientific publishing to highlight the problems of time & trust. With a fantastic group of co-authors, we present The Drain of Scientific Publishing: a ๐Ÿงต 1/n Drain: arxiv.org/abs/2511.04820 Strain: direct.mit.edu/qss/article/... Oligopoly: direct.mit.edu/qss/article/...

Adam Steinbrenner reposted

โ€œThe prohibited activities would include joint research, co-authorship on papers, and advising a foreign graduate student or postdoctoral fellow. The language is retroactive, meaning any interactions during the previous 5 years could make a scientist ineligible for future federal funding.โ€

science.orgU.S. Congress considers sweeping ban on Chinese collaborationsResearchers speak out against proposal that would bar funding for U.S. scientists working with Chinese partners or training Chinese students

Adam Steinbrenner reposted

Adam Steinbrenner reposted

๐Ÿ“ขAnnouncement! The call for ๐“๐๐‰ ๐…๐ž๐ฅ๐ฅ๐จ๐ฐ๐ฌ๐ก๐ข๐ฉ ๐ฌ๐œ๐ก๐ž๐ฆ๐ž ๐Ÿ๐จ๐ซ ๐Ÿ๐ŸŽ๐Ÿ๐Ÿ“ is now open! ๐ŸŒŸ It is designed to offer support and mentorship to researchers transitioning from post-doctoral scientists to principal investigators Info: ๐Ÿ‘‰http://onlinelibrary.wiley.com/page/journal/1365313x/homepage/TPJ-fellowships & in ๐Ÿงต

Adam Steinbrenner reposted

The GRFP announcement from NSF cuts out an entire cohort of 2nd year students from consideration, without warning. This is so deeply unfair that it warrants a formal protest from the scientific community. If someone wants to work with me to craft an open letter and solicit signatures, LMK.

Dan Garisto@dangaristo.bsky.social

New: After a long wait, the GRFP solicitation is live! Deadlines have been extended to early November, so applicants have a bit over a month to submit. www.nsf.gov/funding/oppo...

Very frustrated with NSF GRFP. A 2nd year grad now ineligible after postponing last year. Her pre-grad app was rejected without review for mentioning crop impacts. I'm a previous recipient and served many years as a reviewer. The fellowship needs serious reform, not half-baked solicitation changes

Adam Steinbrenner reposted

I hate this for the second years who had already been working on applications. Also the USDA fellowship RFA has still not been issued for this year. It is harder and harder to find fellowships to support the newest generation of scientists. ๐Ÿงช We are shortchanging our future.

Laura Williams@laurawilliams.bsky.social

NSF GRFP solicitation out. App deadlines now in November. As others noted, eligibility rules for current graduate students now exclude 2nd year grad students. See the solicitation - theyโ€™ve emphasized โ€œfirst yearโ€ and โ€œless than one academic yearโ€ in grad program. www.nsf.gov/funding/oppo...

Adam Steinbrenner reposted

Adam Steinbrenner reposted