Audrey K Ward

Audrey K Ward

@audreykward.bsky.social

Proponent of joy. PhD in Genetics. Postdoc in the LaBella Lab. Probably finding excuses to alliterate. Interested in fungi πŸ„β€πŸŸ«, environmental adaptation πŸ§¬β˜€οΈπŸŒŠ, and advancing STEM education πŸ₯ΌπŸ§‘β€πŸ«. Typos and opinions my own. β€’ she/her

107 followers126 following33 posts

Audrey K Ward reposted

Audrey K Ward reposted

New πŸ“„ 🚨! #CellBio is teeming with simulations comprising an extraordinarily high number of components. We argue that model complexity will not automatically lead to a better understanding of biological systems & discuss how modeling practices could be repurposed: arxiv.org/abs/2608.06998 #philsci

arxiv.orgSimulating is not always understanding: When model complexity obscures biologyIn cell biology, computational models of biological systems range from minimal representations with a handful of parameters to whole-cell simulations tracking thousands of molecular species across a c...

Audrey K Ward reposted

Audrey K Ward reposted

We’re not supposed to post about GRC presentations, but I will reassure the rest of you that yes, even cellular and molecular mycologists all pronounce the word fungi differently. Not to mention species names… #FungalGRC

Audrey K Ward reposted

NSF is devoting a large chunk of increasingly scarce resources to people who are not affiliated with universities. My first read on this is, it's just corruption. It'll be a lot easier for grifters and politically connected dipshits to get their hands on public cash through this mechanism.

Audrey K Ward reposted

Replying to @rexjiang.bsky.social

My first paper w/ Matt, about how mRNA and protein levels of the same genes should be expected to coevolve. It was carried over from my PhD at Michigan w/ George Zhang, but started too late to be in my thesis. academic.oup.com/mbe/article/...

academic.oup.comOn the Decoupling of Evolutionary Changes in mRNA and Protein LevelsAbstract. Variation in gene expression across lineages is thought to explain much of the observed phenotypic variation and adaptation. The protein is close

Audrey K Ward reposted

Maybe not the best phylogeny to use to explain homology. So this pair o' logs are orthologs, but if they arose via duplication and you can recover synteny for one, you could call it a syntelog and the other single log a paralog."

Still mourning #fungal26? Want to celebrate the release of the April 2026 edition of G3? Why not give this a gander? We found impact of low level contamination on population analyses in both Saccharomyces cerevisiae and Aspergillus fumigatus! #mycosky #academicsky

Audrey K Ward@audreykward.bsky.social

Thrilled that work from collaborative efforts by the @dbensasson.bsky.social & @mcmomany.bsky.social labs has been accepted by G3 and is available to read now! Population geneticists beware - low-level contamination has greater impact on analyses than you might expect. doi.org/10.1093/g3jo...

really feeling the kalty shaped hole in our line tonight :( hoping the undisclosed, out day-to-day injury is not too serious because the sirens need her back #pwhl #weewoo🚨

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hype video does have me feeling a type of way despite knowing our next game is v montreal so maybe… maybe we WILL win that one… could be fun! could be VERY cute of us #pwhl #weewoo

really feeling the kalty shaped hole in our line tonight :( hoping the undisclosed, out day-to-day injury is not too serious because the sirens need her back #pwhl #weewoo🚨

back from conference! good news: inspired πŸ’‘, better idea of how to approach some protocols, experiments to add to research plan for a more complete vision πŸ₯Ό bad news: inspired πŸŒŸπŸ•ΆοΈ, have to rework research plan to incorporate experiments 🧬πŸ§ͺ, steak too juicy πŸ₯©, lobster too buttery 🦞🧈 #academicsky

Audrey K Ward reposted

What a way to end #fungal26 We laughed and we cried and we learned so much A great reminder to look back and reflect on the past It can light the way to the future Thank you Nancy Keller for being a light πŸ•―οΈ in the field

Audrey K Ward reposted

Replying to @germhuntermd.bsky.social

Next talk in our #fungal26 session on emerging fungal pathogens is Dr Lisa Couper on genomes of environmental isolates of Coccidioides for tracing human infections

Communication continues! Baoye He shares how cross-kingdom πŸ„πŸŒ± communication happens with extracellular vesicles 🫧 and RNA trafficking πŸš›πŸ§¬ #fungal26

No RNAi, big problems πŸ§¬βž‘οΈπŸ›‘ Mycoviruses 🦠 interfering with RNAi can make fungal pathogen Cryptococcus neoformans more virulent in mouse models. 🐁😷 Fascinating talk from Jun Huang. #fungal26

Jasmine Ono (@jtono.bsky.social) discussing some matchmaking mechanisms gone wrong 😱 πŸ’” Saccharomyces paradoxus and Saccharomyces cerevisiae F1 hybrids are sterile largely due to recombination rejection πŸ›‘βœ‹πŸ» due to mis-segregation of chromosomes πŸ§¬βž‘οΈβ”πŸ€·β€β™€οΈ #fungal26

MarΓ­a AngΓ©lica Bravo NΓΊΓ±ez uses natural isolates of Saccharomyces cerevisiae 🌳🧫 to understand how aneuploidy and structural variation 🧬🧱 changes over time. Take home message (with some of my own soapboxing): don’t just rely on lab strains - look for natural variation in the wild! πŸ•οΈπŸ‡ #fungal26

Hanne Griem-Krey discussing βœ¨πŸš€ Starship-mediated horizontal gene transfer 🧬➑️🧬 of transposable elements in the insect pathogen 🐜😷 Metarhizum anisoplaie. #fungal26

Audrey K Ward reposted

Lluvia Vargas GastΓ©lum shares the fractured πŸ’” genome 🧬 of the Basidiobolus Why are there so many chromomes!? Could it be the LINES near telomeres? #fungal26

Emile Gluck-Thaler elucidating the mysteries πŸ”Ž πŸ«† of fungal variation and phenotype using πŸš€βœ¨ Starship transposon framework. How do these πŸ”— link to and impact fungal evolution? #fungal26

@evelinesnelders.bsky.social shares work utilizing citizen science πŸ‘₯πŸ₯ΌπŸ§ͺ to sample for airborne fungal resistance with Schimmelradar (fungal radar) program πŸ„πŸ“‘ - and some really cool results showing land use is a better predictor for azole resistance! πŸ’ͺ🏻 #fungal26

Audrey K Ward reposted

Jack Gregory explores the diversity of endohyphal πŸ„ bacteria 🦠 of clinical samples of Mucorales He searched πŸ”Ž in WGS data for Mycetohabitans DNA 🧬 Then took that approach to clinical πŸ₯ samples #fungal26

Marie-Claire Harrison tells us how machine learning algorithms πŸ’» can be used to predict and link ⛓️ phenotype-genotype relationships (like antifungal resistance) across clinical and environmental fungi. #fungal26

CNV 1️⃣2️⃣3οΈβƒ£πŸ§¬ has a big influence on drug resistance - Rebecca Shapiro’s group has developed a CRISPR activation system for C. albicans and C. glabrata to overexpress genes and ID those genes associated with resistance. πŸ’ͺπŸ’Š #fungal26

Powerful opening by Aleeza Gerstein to Javier San Juan Galan’s work calling the scientific community to think about how we can include peers who are unable to attend meetings due to visa issues. 🌐🫢 Also - really fascinating work on the variation within clinical populations of C. albicans! #fungal26

Could the rapid multiple drug resistance seen in Candida auris be due to hypermutation? πŸ˜·πŸ’Š David Firer looks into clinical isolates to investigate. πŸ”Ž #fungal26

Absolutely fantastic inaugural Fungal Spore Award talk πŸ† from Matthew Fisher. The Anthropocene is an ongoing fungal evolution experiment - like a game of Spore with real world consequences. πŸ•ΉοΈπŸ¦ πŸ§¬ How does human activity impose selection parameters within fungal evolution? #fungal26

If you’re interested in talking about the random forest prediction of thermotolerance make sure to chat with @taytaypowpow.bsky.social at poster 306C on Friday - and if you want to talk about scaling methods to test these predictions chat with me at 635C on Friday too!!! πŸŒ‘οΈβ„οΈπŸ“ˆ