Bruce Levine, Ph.D. 🇺🇦

Bruce Levine, Ph.D. 🇺🇦

@bllphd.bsky.social

🧬🧪Professor @Pennmedicine #CellTherapy #Genetherapy #Inventor #Kymriah #CARTCell @TmunityTx & @CapstanTx CoFounder, Past President @ISCTGlobal @PNASNexus AE https://orcid.org/0000-0001-6971-8465

2K followers187 following319 posts

Bruce Levine, Ph.D. 🇺🇦 reposted

Replying to @bllphd.bsky.social

We are actively looking to partner with biotech, pharma, and academic groups If you are advancing a program and need a partner who understands both the science and the realities of clinical translation, we should connect www.med.upenn.edu/cvpf/

med.upenn.eduClinical Cell and Vaccine Production Facility (CVPF) | Clinical Cell and Vaccine Production Facility (CVPF) | Perelman School of Medicine at the University of Pennsylvania

Bruce Levine, Ph.D. 🇺🇦 reposted

Replying to @bllphd.bsky.social

We’ve built an integrated platform designed to move programs from discovery into first-in-human studies with rigor, speed, and quality. What differentiates this model is not a single capability, but the integration: • Manufacturing • Process development • QC analytics and correlative science

We’ve built an integrated platform designed to move programs from discovery into first-in-human studies with rigor, speed, and quality. What differentiates this model is not a single capability, but the integration: • Manufacturing • Process development • QC analytics and correlative science

15 year LTFU burdens on patients include: -Frequent visits, testing, requirements -Travel burden and costs, often tied to specialized treating centers -Ongoing disruption to work, family life, and daily routines -Psychological burden of prolonged monitoring with diminishing clinical yield

Top 5 #FDA Takeways 1) NGS now the regulatory backbone for genome editing safety 2) FDA wants layered approach to off-target assessment 3) Low-frequency events matter, must be detectable 4) Patient genetics now part of risk assessment 5) Genome integrity no longer optional for DSB-based gene editors

Bruce Levine, Ph.D. 🇺🇦 reposted

What the peptide craze reveals about Americans’ relationship with risk. Great piece from @sarah-todd.bsky.social www.statnews.com/2026/04/06/r... It's so odd how many people will not trust proven biomedical approaches but embrace and literally shoot up with unproven things like peptides

statnews.comWhat the peptide craze reveals about Americans’ relationship with riskWhy do RFK Jr. and other health influencers embrace unproven peptides while calling for more research into well-studied vaccines?

Bruce Levine, Ph.D. 🇺🇦 reposted

Bruce Levine, Ph.D. 🇺🇦 reposted

From Pink Sheet on continued departures from FDA’s biologics division and challenges backfilling openings. FDA biologics center reported 106 departures from Jan. 1 to June 30. These numbers don’t include the 100-150 who were part of the reduction-in-force insights.citeline.com/pink-sheet/a...

insights.citeline.comUS FDA’s Biologics Center Departures Grew Before More Than 100 RIFs ExitedThe Center for Biologics Evaluation and Research saw departures far outnumber new hires in the second and third quarters of FY 2025, before more than 100 people left July 14 after the reduction-in-for...

There should be a cable channel fact checking all the cable news channels and their paid "pundits" in real time

KFF Health News@kffhealthnews.org

CNN pundit Scott Jennings said almost 5 million nondisabled Medicaid recipients “simply choose not to work” and “spend six hours a day socializing and watching television.” KFF Health News + @politifact.bsky.social rate this statement False. Read why. ⤵️ kffhealthnews.org/news/article...

Bruce Levine, Ph.D. 🇺🇦 reposted

🚨Worse than you think "World’s premier cancer institute faces crippling cuts and chaos" There used to be bipartisan support. Now: -Rat on your colleagues -Silencing the science communicators -A budget to ‘destroy clinical research’ #NCI #NIH #Cancer #cancerresearch www.cnn.com/2025/07/08/h...

cnn.comWorld’s premier cancer institute faces crippling cuts and chaos | CNNThe Trump administration’s broadsides against scientific research have caused unprecedented upheaval at the National Cancer Institute, the storied federal government research hub that has spearheaded ...