Böke Lab

What does an ovary actually look like as it ages—one oocyte at a time? We mapped >85,000 oocytes in >100 intact mouse ovaries, in 3D, across the reproductive lifespan. And the ovary turned out to be much more organized than we expected. 🧵 1/5 www.nature.com/articles/s43...

I am extremely impressed by the developments in Czech science over the last years. The #ERC_CZ program was one of the smartest moves in science policy Europe-wide. Great value for money. This budget proposal is a disaster and kills the amazing work done over many years. Spectacular own-goal.

Lead the next discovery at the LMB. We’re recruiting Group Leaders to join our Structural Studies and @cellbiol-mrclmb.bsky.social Divisions. Benefit from long-term support, access to outstanding core-facilities and a collaborative environment where science thrives. ➡️ mrclmb.ac.uk/research-lea...

Our Dept. of Genetics and Developmental Biology at the Institut Curie in the heart of Paris is hiring a new junior PI. It has a nice start up package and excellent I. Curie facilities. Please spread the word: Deadline Dec. 18th! jpi-recruitment-curie-umr3215-u934.curie.fr

🤩 Excited to present today how stem cell enlargement drives dysfunction in hematopoietic stem cells during aging at the @EMBO Cell Cycle Conference in Lisbon! 🔬 Looking forward to seeing friends and colleagues, and to hearing about the AMAZING research from the field! 🧬✨

The ovary actively 'counts' its eggs, preparing the same proportion for ovulation, at different stages of life 📹 Arturo D’Angelo et al @bokelab.bsky.social @crg.eu in @nataging.nature.com ➡️ bpod.org.uk/archive/2026... with John Ankers

How are mRNAs linked to molecular motors in mammalian cells? In our new preprint, we show that FXR1/2 are RNA adaptors for the microtubule motor dynein. Our findings have also prompted us to rethink how activating adaptors contribute to motor-based transport (1/n)

We are looking for a research assistant! Come join the team: www.jobs.ac.uk/job/DSZ826/r...

21627 applications. Nothing to celebrate here. Impossible to evaluate fairly & safely. Neither the science (too diverse & possibly LLM generated) nor the soft criteria (likely LLM generated). Without an interview stage - a security risk! marie-sklodowska-curie-actions.ec.europa.eu/whats-new/ne...

Really happy and honoured! Thank you so much!

Noemi Zollo's work is highlighted on the Collège de France website: www.college-de-france.fr/fr/actualite... Many thanks to the @cirbcdf.bsky.social , @college-de-france.fr, @cnrs.fr, @cnrsbiologie.bsky.social, @inserm.fr, @sorbonne-universite.fr, @ibdm.bsky.social

Excited to share this fantastic collaboration with the teams of @mhverlhac.bsky.social and @bokelab.bsky.social, where we identify and characterise the Zollo body — a transient RNP compartment that drives oocyte and follicle growth! 🥚🔬 www.science.org/doi/10.1126/...

A transient RNP compartment boosts translation and growth of mammalian oocytes | Science Advances www.science.org/doi/10.1126/...

Happy Sunday with a great issue of #cebooc! This week Qingling Yang and team reveal how leaky mitochondria drive oocyte aging: pubmed.ncbi.nlm.nih.gov/42665751/ The Verlhac team discovered a new super-organelle linked to translation and growth in mouse oocytes: pubmed.ncbi.nlm.nih.gov/42664359/

Kelly Nguyen, Group Leader in the LMB’s Structural Studies Division, has been awarded the 2027 Francis Crick Medal and Lecture from @royalsociety.org. Read more about @kellythd-nguyen.bsky.social’s research on telomerase here: mrclmb.ac.uk/news-events/... #LMBNews

Revisiting metabolic fundamentals In this post on the Node, Liliana Piñeros & @diegosainzdelamaza.bsky.social report on the Workshop, ‘Revisiting metabolic fundamentals,’ aimed at reframing metabolism as an information-processing and signalling system. thenode.biologists.com/revisiting-m...

🗺️ First 3D map of ovary throughout reproductive lifespan reveals it counts its own eggs A new study published in #NatureAging by @crg.eu researchers challenges the idea that ovaries are simply passive egg reservoirs @bokelab.bsky.social #BISTCommunity Learn more 👉 bist.eu/first-3d-map...

🔬Big news🥳 We’re excited to welcome Prof. Dr. Rosa Lozano-Durán as new Director and head of the Department of Plant Virology @mpipz.bsky.social Her research focuses on how plant viruses interact with their hosts. 🎉Welcome to MPIPZ, Rosa 🌿🌱 www.mpipz.mpg.de/5842514/loza...

Do you need to think about something else after the amazing #eclipse experience 😎? Check our latest work with @bokelab.bsky.social, together with @danifranco93.bsky.social and using @biapyx.bsky.social, of course 🤗 @informatikaehu.eurosky.social @dipcehu.bsky.social

Happy Sunday with another issue of #cebooc! @bokelab.bsky.social shows the dynamics of follicle depletion with age using whole 3D imaging of intact ovaries: pubmed.ncbi.nlm.nih.gov/42587142/ full issue: biomed.news/bims-cebooc/... subscribe: biomed.news/bims-cebooc @biomednews.bsky.social

Delighted to see this published! 🎉 Why do cells invest in such tight control of tubulin synthesis? @ac-almeida.bsky.social shows that even small increases in tubulin levels alter microtubule dynamics and disrupt multicellular architecture and viability. Bravo to the whole team 👏! 👉 rdcu.be/fu8ek

Read our latest testimonial from @gzaffagnini.bsky.social from the @unicologne.bsky.social. He has been curating his report on cell biology of #oocytes since June 2024 and recently released his 100th issue. You can subscribe to his report by going to biomed.news/bims-cebooc

Paying peer reviewers Interview with @danielgorelick.bsky.social about @biologyopen.bsky.social Fast & Fair trial in which peer reviewers were paid £220/review Spoiler: it works - fast, high quality reviews www.nature.com/articles/d41...

Exactly my thoughts re the "unbiased" QED 1% list- this analysis puts it on firmer footing. One thing not captured here is the prominence of well-established authors; that's what triggered me whether QED was really ranking the science OR influenced by signals assoc'd w/ scientific prominence- EB

Much deserved - congratulations both!! :) - EB @dudinlab.bsky.social @gautamdey.bsky.social

Science really takes a village. Thrilled to share this with my friend @dudinlab.bsky.social, and with our brilliant and fearless teams, our collaborators around the world and our mentors - in my case a special shoutout to Buzz Baum, Jan Ellenberg and @monicabettencourt.bsky.social. 1/2

That's right! EQDB made it all the way to Japan 🇯🇵! Many thanks to @laghalab.bsky.social @juliebatut.bsky.social @robinjournot.bsky.social @leopoldlab.bsky.social @clotilde-cadart.bsky.social Vincent, Emma, Miquel, Clara and Kai! Join us @sfbd.bsky.social for more outreach activities

Is this the future of peer review? New from @biologyopen.bsky.social: expanded Fast & Fair trial paying reviewers £220 per paper The result: rapid peer review with no drop in quality or change in acceptance rate Paying referees makes peer review faster & fairer www.biorxiv.org/content/10.6...

Huge congrats to the CRG's Mafalda Dias for being one of eight finalists for the 2026 Premio Vanguardia de la Ciencia, one of Spain's most visible science prizes. Voting is open now and closes on Sunday 28 June at 23:59 (peninsular time).

New paper from the Yasin Dagdas (@plantophagy.bsky.social) group, this time in @science.org, on how plant cells cope with viral infection and how selective autophagy delays cell death to give plants a chance to survive. Chapeau and congratulations to all the authors! www.science.org/doi/10.1126/...

This award is such a beautiful surprise! 🤩 Tons of thanks to the @royalmicrosoc.bsky.social, the amazing #BioimageAnalysis, #Fiji, #ImageJ & #OpenSource communities, my mentors and mentees, my employers, and whoever nominated me (I still don't know how that person was 😅)!

Register now for the EMBO Workshop "The cell cycle: Exploring conservation and divergence in life's engine" in #Lisbon, Portugal, 5–7 October 2026. Registration by 31 May Abstract submission by 15 June https://meetings.embo.org/event/26-cell-cycle #EMBOCellCycleEvolution #meeting #EMBOevents 🧪

It was amazing to participate in #PeopleinRed fundraiser Gala, as a guest of the mayor of Barcelona! A lovely reminder that science reaches far beyond the lab -- EB

Thank you to organisers @lydiafinley.bsky.social and @wilhelmpalm.bsky.social and everyone who joined us at this week's Workshop on 'Revisiting Metabolic Fundamentals' biologists.com/workshops #BiologistsWorkshops @dmmjournal.bsky.social

Inside Palantir, people are finally waking up to the fact that they might actually be the bad guys Great reporting once again from @makenakelly.bsky.social www.wired.com/story/palant...

🚨 Registration closing soon! Join the AIM-Net Deep Learning Summer School (2–6 June 2026, La Ràpita 🇪🇸) 🔬 Hands-on training in AI for microscopy & bioimage analysis 👩‍🔬 For PhDs & early-career researchers 💻 Lectures + practicals + project work ⏳ Apply before April 10 aim-net.net/eventos/aim-...

Honored to receive a La Caixa Junior Leader Fellowship @caixaresearch.bsky.social at @crg.eu. This recognition will support our research on oocyte dormancy and proteostasis for the next three years🥚! Big thanks to previous funders @embo.org & MSCA @ec.europa.eu and to @bokelab.bsky.social @prbb.org!

Every gift has a story. Here’s why MBL donor and supporter Mark Terasaki gives to the MBL—and today, your impact is doubled when you give too. Each gift made today will be matched dollar-for-dollar up to $50,000. Make your impact now: mbl.edu/give

A white paper on Stem Cell Based Embryo Models #SCBEM #Innovation #Ethics #Policy, from the community to highlight the potential of this new area of research and its impact in #ReproBiology shorturl.at/dAWL2

12 days left to apply! @bokelab.bsky.social @crg.eu @prbb.org See here: recruitment.crg.eu/content/jobs...

Interested in one of the top jobs in European biology? @embo.org has opened a call for its next Director, to succeed Fiona Watt Really spectacular opportunity! Spread the word... www.embo.org/features/emb...

On the occasion of International Women’s Day at @crg.eu, we are pleased to welcome : Marie-Émilie Terret (CIRB, @college-de-france.fr), who will speak on “Mechanics of Oocyte Divisions” Hosted by @adelaljord.bsky.social 📅 When? Monday, March 9th, 2026 - 12:00–13:00 - Aula Room, @prbb.org