Christian Bartels

Christian Bartels

@chriba.bsky.social

Interested in data ... pharmacometrics, causal inference, ..., risk management, cheminformatics, molecular modeling, protein structure determination, peptide sequencing | Basel https://scholar.google.com/citations?user=R3QYvdUAAAAJ

125 followers222 following62 posts

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Replying to @chriba.bsky.social

Single-world intervention graphs (SWIGs) as distributions. Conceptually, simultaneously related to and distinct from Rubin's framework and Pearl's calculus. doi.org/10.48550/arX... #SWIG #DAG #causal #identification #frontdoor #docalculus

doi.orgSingle World Intervention Graphs as Distributions: A Framework for Causal IdentificationCausal inference seeks to estimate the effect of an intervention on an outcome using observed data, typically via Rubin's potential-outcome framework or Pearl's do-calculus. Following section 9 of Ric...

The data generating process: something that does not exist. Invented by scientists to earn their living.

Michael "Shapes Dude" Betancourt@betanalpha.bsky.social

Do you want to faithfully quantify false/true positive rates in a significance test? Model the entire data generating process. Faithfully calibrate an estimator? Model the entire data generating process. Design productive experiments? Model the proposed data generating process.

Christian Bartels reposted

+ + BREAKING ++ Switzerland votes in one year. Latest polls suggest the radical right SVP could surpass its 2015 record, approaching 30%. But rather than framing this as a surge, the story of the SVP: a relatively stable electoral base, alongside an increasing number of defeats at the ballot box

Christian Bartels reposted

Uruguay, with 3.5 million people, generates 98% of its electricity from renewable sources. The architect of that transformation, Ramón Méndez Galain, put it simply: "The key is not technology; it is institutions. Once the rules are fair and predictable, the system builds itself."

irishexaminer.comOur solar power model isn't working — there's a fairer waySolar lease-to-own could unlock Ireland's energy future — Uruguay, the Netherlands and Germany have all made this work with straightforward rules, writes Mary Teehan

Causal inference without do-calculus nor potential outcomes. An important simplification? #causal #causal_inference #swig #docalculus #identification

Christian Bartels@chriba.bsky.social

Single-world intervention graphs (SWIGs) as distributions. Conceptually, simultaneously related to and distinct from Rubin's framework and Pearl's calculus. doi.org/10.48550/arX... #SWIG #DAG #causal #identification #frontdoor #docalculus

Christian Bartels reposted

Coding agents like Claude Code feel like magic but they’re really a bunch of tools in a trenchcoat. This week I build a working coding agent in R, starting from just three tools. I’ll add some extra tools to make it safer and more efficient. tidydesign.substack.com/p/a-coding-a...

tidydesign.substack.comA coding agent is six functions in a trenchcoatCoding agents like Claude Code, Cursor, and Codex have taken the software engineering field by storm. What makes them tick?

Christian Bartels reposted

Many of us can save a child's life, if we rely on the best data. Giving money to a charity is one of the best things you can do for others. Your donation can make a huge difference. But whether or not your donation makes a difference greatly depends on *where* you donate.

Christian Bartels reposted

It's alive! 🎉 𝗧𝗵𝗲 𝗗𝗮𝘁𝗮 𝗔𝗻𝗮𝗹𝘆𝘀𝘁'𝘀 𝗚𝘂𝗶𝗱𝗲 𝘁𝗼 𝗖𝗮𝘂𝘀𝗲 𝗮𝗻𝗱 𝗘𝗳𝗳𝗲𝗰𝘁 is out -- an introduction to causal inference in practice. The first two chapters are available for free here: theissbendixen.com/dag-book/ More below 👇

Christian Bartels reposted

In unsicheren Zeiten brauchen wir stabile Beziehungen zu Europa. Aber die Chaos-Initiative reisst genau diese Brücken ein – sie ist politisch und wirtschaftlich ein Eigentor, das unsere Sicherheit und unseren Wohlstand gefährdet.

Christian Bartels reposted

Finally uploaded a revised version of this preprint on parameter identifiability arxiv.org/abs/2502.04867. Approach called 'invariant image reparameterisation' though 'image' used in mathematical sense not picture sense. Took me a while to revise for various reasons, but fairly happy with it now

Christian Bartels reposted

One week away! Don't miss the next Methods Series presentation with Alex Ocampo.

CAUSALab@causalab.org

Alex Ocampo continues the 2026 Methods Series speaker lineup in 2 weeks @ki.se 👇 "Simplifying Causal Mediation Analysis for Time-to-Event Outcomes using Pseudo-Values." 📆 April 7, 2026 ⏰ 15.00 CEST/9.00 EDT 📍 Online Register to attend: stats.sender.net/forms/e7JD1d...

Christian Bartels reposted

The median age in China has rapidly caught up with the United Kingdom— In 1965, the median age in the United Kingdom was almost twice that of China. Half of the people in the UK were younger than 34 years, and half were older. In China, this midpoint was just 18 years.

Christian Bartels reposted

📣The 2026 Symposium of #CausalInference in the #HealthSciences takes place on March 18, 2026 in Fribourg. Theme: AI & machine learning in causal inference for health sciences 🎤Keynotes: Elsa Gautrain, Aurélien Sallin, Jonas Peters, Jana Mareckova 🔗https://projects.unifr.ch/pophealthlab/?page_id=1561

We apply the estimand framework to dose–exposure–response analyses. ... strategy to improve exposure–response analyses for dose selection, particularly when the relevant evidence includes data from multiple studies. #estimand #exposure-response #dose-response #causal doi.org/10.1002/psp4...

doi.orgSome Common Dose–Exposure–Response Estimands and Conditions for Their Causal IdentifiabilityExposure–response analyses are central to dose selection in drug development. The estimand framework, formalized in ICH E9(R1) regulatory guidance, provides a structured approach to define scientific...

Christian Bartels reposted

Christian Bartels reposted

I'm so excited to announce the first release of my newest #Rstats package, {adrftools}! This package facilitates estimation, visualization, and testing for the causal effect of a continuous (i.e., non-discrete) treatment. 🧵 1/10 #statssky #episky #causalinference

cran.r-project.orgadrftools: Estimating, Visualizing, and Testing Average Dose-Response FunctionsFacilitates estimating, visualizing, and testing average dose-response functions (ADRFs) for characterizing the causal effect of a continuous (i.e., non-discrete) treatment or exposure. Includes suppo...

Christian Bartels reposted

Replying to @lakens.bsky.social

As I said, this is the important work that needs to be done. Mark's paper is overly simplistic, arguing we can't judge deviations at all. Deviations are in practice not remotely as bad as he wants. If he had collected actual data,che would have falsified his own claims.

Christian Bartels reposted

This is a fairly technical but highly relevant paper on how we can model complex systems at various levels of detail without losing causal content. Think gas: instead of tracking every molecule, we can focus on big-picture properties like temperature and pressure. www.auai.org/uai2017/proc...

Christian Bartels reposted

What are some of the best DAGs you seen that depict time-varying confounding? Could be from a 'real' worked example, or generic. #EpiSky

Christian Bartels reposted

“Uruguay did what most nations still call impossible: it built a power grid that runs almost entirely on renewables—at half the cost of fossil fuels. The physicist who led that transformation says the same playbook could work anywhere—if governments have the courage to change the rules.”

forbes.comUruguay’s Renewable Charge: A Small Nation, A Big Lesson For The WorldUruguay built a power grid that runs 99% on renewables—at half the cost of fossil fuels. Here’s how its bold energy overhaul became a global model.

Christian Bartels reposted

Replying to @altmetric.com

X/Twitter's rough full volume is around 500 total million posts every day, or 182 (and a half) billion posts per year. By contracts, we found 11.2 million research posts in all of 2025 on there. In other words, 0.000006% of Twitter appears to be sharing research. Basically zero.

This gives financial institutions leeway to acquire hard-to-sell, higher-yielding long-term assets and finance them with cheaper short-term liabilities, thus increasing profits through a risky “mismatched book”.

The Economist@economist.com

A former top banker predicts that an unreformed pay system and the gutting of regulation will accelerate the next financial crisis

Christian Bartels reposted

link 📈🤖 Demystifying Proximal Causal Inference (Ringlein, Nguyen, Zandi et al) Proximal causal inference (PCI) has emerged as a promising framework for identifying and estimating causal effects in the presence of unobserved confounders. While many traditional causal inference methods rely on the

Christian Bartels reposted

Lumo now understands LaTeX. Type any formula (fractions, matrices, integrals, etc.) straight into chat and see it rendered instantly. No more screenshots or ASCII tricks. Perfect for precise technical work and academic tasks. Try it now: https://lumo.proton.me

Christian Bartels reposted

Students learn early that correlation does not imply causation. Correct, but incomplete... Certain patterns of independence and conditional dependence constrain #causal structure very strongly. A simple example:

Christian Bartels reposted