Christian Münch

Christian Münch

@cmunch.bsky.social

Professor at Goethe University Frankfurt || proteostasis, mitochondria, autophagy, protein quality control, translation, infection, cancer, neurodegeneration || proteomics, molecular systems biology, cell biology || https://molsysmed.de

940 followers441 following13 posts

Christian Münch reposted

🎉 In the final round of the ExStra Program of the DFG, the CPI has been selected & is honored with funding for another 7 years! 🏆 With the vision that “precision biology drives precision medicine”, funds will be used for high-risk, innovative research for cardiopulmonary health ❤️🫁!

Christian Münch reposted

Super excited to share our latest work on deciphering the #Ubiquitin Code “𝗨𝗯𝗶𝗥𝗘𝗔𝗗 𝗱𝗲𝗰𝗶𝗽𝗵𝗲𝗿𝘀 𝗽𝗿𝗼𝘁𝗲𝗮𝘀𝗼𝗺𝗮𝗹 𝗱𝗲𝗴𝗿𝗮𝗱𝗮𝘁𝗶𝗼𝗻 𝗰𝗼𝗱𝗲 𝗼𝗳 𝗵𝗼𝗺𝗼𝘁𝘆𝗽𝗶𝗰 𝗮𝗻𝗱 𝗯𝗿𝗮𝗻𝗰𝗵𝗲𝗱 𝗞48 𝗮𝗻𝗱 𝗞63 𝘂𝗯𝗶𝗾𝘂𝗶𝘁𝗶𝗻 𝗰𝗵𝗮𝗶𝗻𝘀” @cp-molcell.bsky.social 1/8 www.cell.com/molecular-ce...

cell.comUbiREAD deciphers proteasomal degradation code of homotypic and branched K48 and K63 ubiquitin chainsUbiquitin chains determine the fates of their modified proteins, including proteasomal degradation. Kiss et al. present UbiREAD, a technology to monitor cellular degradation and deubiquitination at hi...

Christian Münch reposted

Christian Münch reposted

Christian Münch reposted

Christian Münch reposted

Just one week left to apply!

David Balchin@davidbalchin.bsky.social

We're hiring a postdoc! Applications from any nationality welcome. Projects around protein folding in cells, ribosomes, chaperones etc. 4 yr contract, fantastic research environment @crick.ac.uk crick.wd3.myworkdayjobs.com/External/job...

Christian Münch reposted

Christian Münch reposted

Our paper on Stopless-ORF Circular RNAs (socRNAs) is now out in Cell. By high-res tracking and comparing translation by either single or multiple ribosomes, we find that ribosomes cooperate to overcome pausing to ensure fast and efficient translation www.cell.com/cell/fulltex...

cell.comLong-term imaging of individual ribosomes reveals ribosome cooperativity in mRNA translationRibosomes cooperate through transient collisions to ensure efficient translation.

Christian Münch reposted

We are very excited to share that the recent research from our lab has been published in Nature Biotechnology! Thanks to our lab members and our collaborators for contributing to this project and especially to Laurentz for driving this exciting research! www.nature.com/articles/s41...

nature.comA human metabolic map of pharmacological perturbations reveals drug modes of action - Nature BiotechnologyMapping the metabolic effects of drugs helps define their mode of action.

Christian Münch reposted

Thrilled to see this paper out!! 🧪 Spatial transcriptomics of brain aging and 'spatial aging clocks' identify cells that have pro-aging or pro-rejuvenating effects on their neighbors! Huge CONGRATS to Eric Sun and all authors! Fantastic collaboration with @jameszou.bsky.social! rdcu.be/d33uQ 🧵

rdcu.beSpatial transcriptomic clocks reveal cell proximity effects in brain ageingNature - A spatially resolved single-cell transcriptomics map of the mouse brain at different ages reveals signatures of ageing, rejuvenation and disease, including ageing effects associated with T...

What a great joy to meet up with the PROGENIE group to discuss the future of #proteostasis and all the topics of new and not-anymore-so-new PIs. Join us next time if you are a new PI in Europe working on proteostasis, 👉https://molsysmed.de/project/proteostasis-group-of-european-new-investigators

🥳Excited to join the Bsky Science community! 🥳 Today marks 8 years at Goethe University—an incredible journey from group leader @ibc2-gu.bsky.social to full professor and Director of the Institute of Molecular Systems Medicine. Grateful for the invaluable support and amazing people along the way!

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