Dan MacGuigan

Dan MacGuigan

@dmacguig.bsky.social

DJM Computational Biology, LLC. Smithsonian NMNH Independent Contractor - bioinformatics, systematics, genomics, speciation, & hybridization - University of Rochester undergrad, Yale EEB PhD, University at Buffalo NSF PRFB. https://danjmac.weebly.com

1.6K followers629 following32 posts

Dan MacGuigan
@dmacguig.bsky.social

New paper in Systematic Biology! We show how micro-synteny can help resolve a tricky fish #phylogenetic problem where traditional sequence-based analyses fall short. Genomes archive evolutionary history in more than just their basepairs. doi.org/10.1093/sysb... #fish #genomics #evolution

Dan MacGuigan
@dmacguig.bsky.social

Check out our new paper! We debut the #R package PhenoDelimit, a simple #ML approach to morphological species delimitation without a priori lineage assignment. Plus we describe a new darter species, 𝘼𝙡𝙡𝙤𝙝𝙞𝙨𝙩𝙞𝙪𝙢 𝙖𝙣𝙖𝙨, endemic to the Duck River system in TN. doi.org/10.1093/sysb... #fish #genomics

doi.orgGenomic and Phenotypic Delimitation of Species in a Temperate Aquatic Biodiversity HotspotAbstract. Biologists have relied on morphological characteristics to identify, define, and formally describe species for the past 250 years. The advent of
Dan MacGuigan
@dmacguig.bsky.social

Check out our new paper! We debut the #R package PhenoDelimit, a simple #ML approach to morphological species delimitation without a priori lineage assignment. Plus we describe a new darter species, 𝘼𝙡𝙡𝙤𝙝𝙞𝙨𝙩𝙞𝙪𝙢 𝙖𝙣𝙖𝙨, endemic to the Duck River system in TN. doi.org/10.1093/sysb... #fish #genomics

doi.orgGenomic and Phenotypic Delimitation of Species in a Temperate Aquatic Biodiversity HotspotAbstract. Biologists have relied on morphological characteristics to identify, define, and formally describe species for the past 250 years. The advent of

Dan MacGuigan reposted

Pia Schwarz
@pfschwarz.bsky.social

I am very excited to share our new paper with my amazing co-authors and mentors @dmacguig.bsky.social @fishgenomes.bsky.social @tjnear.bsky.social . We investigate a secondary contact zone in #darters. track.smtpsendmail.com/9032119/c?p=...

track.smtpsendmail.comMosaic tri-lineage secondary contact shapes diverse genomic outcomes in dartersAbstract. Speciation does not always lead to complete reproductive isolation, which can result in hybrid zones with gene flow. In freshwater fishes, second

Dan MacGuigan reposted

Dan Garisto
@dangaristo.bsky.social

In addition to the terminations of existing awards, new NSF grants are still stopped completely since DOGE was granted access to systems a week ago. Last Thursday, an agency spokesperson said "NSF continues to issue awards." That does not appear to be the case.

Dan MacGuigan
@dmacguig.bsky.social

Thank you @sse-evolution.bsky.social! Thrilled to have our paper recognized.

Chase Brownstein@chasedbrownstein.bsky.social

I am beyond honored to announce that our paper (academic.oup.com/evolut/artic...) revealing a molecular mechanism of evolutionary stasis has won the @sse-evolution.bsky.social President's Award This work would have been impossible w/o my colleagues @tjnear.bsky.social lab and beyond!

academic.oup.comThe genomic signatures of evolutionary stasisAbstract. Evolutionary stasis characterizes lineages that seldom speciate and show little phenotypic change over long stretches of geological time. Althoug

Dan MacGuigan reposted

Alejandro Alvarez
@aletakesphotos.bsky.social

USAID staff have two days to clean out their offices at the agency’s former headquarters in DC. People are gathering on the sidewalk in the rain to show their support, applauding workers as they pass by.

Dan MacGuigan
@dmacguig.bsky.social

Very grateful to have contributed to this important research!

Tom Near@tjnear.bsky.social

1/4New from the #NearLab, genomics and morphology demonstrate the famous Snail Darter, Percina tanasi, the little fish that swam to the United States Supreme Court is not a distinct species... Open access at Current Biology www.cell.com/current-biol...

Dan MacGuigan reposted

Alex Wild
@alexwild.bsky.social

I hope federally funded scientists are preparing for large scale, bad faith attacks by Musk and his troll army. It’s pretty clear the DOGE operation is going to take snippets of grant proposals and papers, present them out of context, and direct weaponized harassment of individual people.

Dan MacGuigan reposted

Alex Wild
@alexwild.bsky.social

Replying to @alexwild.bsky.social

Elon Musk takes far more federal dollars with far less oversight than any of the public scientists facing attacks. People who come under attack should respond by making sure anyone listening knows how much federal money Musk makes, and how he shields it from scrutiny.

Dan MacGuigan reposted

Michael Landis
@landismj.bsky.social

Here's a starter pack for early career researchers in evolutionary biology. I prioritized the most-junior folks, and this list quickly filled up with undergrads, grad students, and postdocs. Might do another list later, but I'm tired. Have fun everyone! 🐒 #evobio go.bsky.app/MzND7nX

Dan MacGuigan
@dmacguig.bsky.social

First day on the job as a NOAA Fisheries Research Biologist, stationed at the National Systematics Lab in the Smithsonian National Museum of Natural History. I'll be developing and streamlining bioinformatics workflows, as well as leading and supporting research on systematics, evolution, and more!

Dan MacGuigan
@dmacguig.bsky.social

Check out our new paper! Gars have an extremely low rate of molecular evolution compared to other vertebrates, much slower than most other "living fossil" lineages. With co-lead Chase Brownstein, plus Daemin Kim, Oliver Orr, Liandong Yang, @solomonrdavid.bsky.social, Brian Kreiser, and Tom Near.

doi.orgThe genomic signatures of evolutionary stasisAbstract. Evolutionary stasis characterizes lineages that seldom speciate and show little phenotypic change over long stretches of geological time. Although lin

Dan MacGuigan reposted

Dr. Solomon David
@solomonrdavid.bsky.social

LIVING FOSSILS: They GAR for REAL. www.science.org/content/arti... Thanks @scattercushion.bsky.social for the story in Science, see article for link to research paper led by Chase Brownstein et al! 🧪🐟

Amanda Heidt@scattercushion.bsky.social

🧪I've done it, I've drunk of the gar KoolAid! Big thanks to @solomonrdavid.bsky.social and co for sharing this study with me. Read on to learn about how fish whose last common ancestor lived during the time of the dinosaurs can produce fertile hybrids today! www.science.org/content/arti...

Dan MacGuigan reposted

David Shiffman, Ph.D. 🦈
@whysharksmatter.bsky.social

In which I post a daily shark fact 🦈🧪🦑 🌎 on Bluesky every day unless I forget in which case they’ll be more like daily-ish: Sharks absolutely get cancer. Even if they didn’t, eating shark doesn’t cure cancer, just like eating LeBron James doesn’t make you better at basketball.

sportdiver.comCan Sharks Get Cancer?In this installment of Ask a Marine Biologist, Dr. David Shiffman tackles a frequently asked question about sharks.

Dan MacGuigan reposted

Tracy Heath
@trayc7.bsky.social

Hi 👋🏼 Bluesky pals! I'm still trying to make the shift to this site. I guess it's nice that this place feels familiar. I'm going to be posting about the SACNAS #2023NDiSTEM conference this week. Find me at the Evolutionary Biology Societies booth #907 if you're here, too!