Pinned
🚨4-year PhD position with @tinearnvig.bsky.social and me How do genetically identical bacteria generate multiple phenotypes, maximising survival in case of sudden catastrophes like nutrient starvation or host immunity?
Eachan Johnson
@eachan.scbir.org
Group leader at The Francis Crick Institute in London. Opinions are my own. he/him 🦠 M. tuberculosis, K. pneumoniae, other pathogenic bacteria 🧫 antimicrobial resistance 🧬 molecular genetics ⚗️ chemical biology
184 followers211 following20 posts
Pinned
🚨4-year PhD position with @tinearnvig.bsky.social and me How do genetically identical bacteria generate multiple phenotypes, maximising survival in case of sudden catastrophes like nutrient starvation or host immunity?
Eachan Johnson reposted
FACULTY POSITION: We are seeking an Assistant Professor to join our growing and vibrant Department of Microbiology at Cornell! FOCUS: Using bacteria to address 21st century challenges. (part of a cohort hire in SynBio). *please repost* academicjobsonline.org/ajo/jobs/33098 #MicroSky
Eachan Johnson reposted
We are looking for a PhD student to join us in London next year! Are you interested in genetic screens? Host-pathogen interactions? Intestinal biology? Our lab applies curiosity driven research within medically relevant models of pathogenesis. Interested? Apply here: bit.ly/4icnsqM
Application instructions and portal are below. Apply before 4 November. crick.wd3.myworkdayjobs.com/External/job...
🚨4-year PhD position with @tinearnvig.bsky.social and me How do genetically identical bacteria generate multiple phenotypes, maximising survival in case of sudden catastrophes like nutrient starvation or host immunity?
Eachan Johnson reposted
Come and join my group at @oxfordchemistry.bsky.social! We have an opening for a postdoc position in photopharmacology. Prior experience with photoswitches and photopharmacology essential. Deadline 27th April. For more details see my.corehr.com/pls/uoxrecru... #Chemsky
Instructions and application link here: crick.wd3.myworkdayjobs.com/External/job...
Eachan Johnson reposted
The latest AI/ML tools for co-folding proteins around small molecule ligands can produce impressive results. Until you start looking at them closely.
Eachan Johnson reposted
Very excited to share our recently published work on NTM and their response to acid stress! As my first paper, I’m especially grateful for the support and guidance from @luizcarvalholab.bsky.social , Rachel and @maxgg.bsky.social . More to come!
Very happy to see this out! Great work by @lockwop.bsky.social @crick.ac.uk and first paper on NTMs from the lab! Parise made a set of 12 fluorescently labelled NTMs covering environmental and opportunistic mycobacteria... onlinelibrary.wiley.com/doi/10.1111/...
Eachan Johnson reposted
Are you interested in being the first biologist in our new team? Come join our small but growing group. Deadline for applications is 3rd March. #Tuberculosis 🧪🦠 #TBDrugDiscovery
Eachan Johnson reposted
I am happy to share our recent publication in @nature.com on a mucosal immunization strategy that clears C. difficile colonization in mice. Congratulations to Audrey Thomas, lead author on the work. www.nature.com/articles/s41...
📢 4-year PhD position in my lab at @crick.ac.uk Using active learning & chemical genomics to find new antibiotics with new targets in pathogenic bacteria. Looking for: chemistry / chem bio / comp bio / micro backgrounds with coding interest. Deadline 17 March. www.crick.ac.uk/careers-stud...
I’m looking forward to this incredible opportunity to advance the science of antibiotic discovery with the Gr-ADI consortium.
A research team from the Crick led by @eachan.scbir.org has joined a three-year, international collaboration to tackle antibiotic resistant bacteria. The partnership is championed by the Gates Foundation, @wellcometrust.bsky.social and @novo-nordisk.bsky.social. www.crick.ac.uk/news/2026-02...
Eachan Johnson reposted
FoldMason is out now in @science.org. It generates accurate multiple structure alignments for thousands of protein structures in seconds. Great work by Cameron L. M. Gilchrist and @milot.bsky.social. 📄 www.science.org/doi/10.1126/... 🌐 search.foldseek.com/foldmason 💾 github.com/steineggerla...
Eachan Johnson reposted
www.findaphd.com/phds/project... interested in bacterial antagonism? PhD opportunity in our team, see below. Please repost!
Eachan Johnson reposted
I am looking for a postdoc to develop high-performance algorithms in computational genomics. Email or DM me if interested. For more information, see hlilab.github.io/vacancies. RTs appreciated!
Eachan Johnson reposted
Eachan Johnson reposted
We’re excited to share our latest study that reshapes our understanding of Mycobacterium tuberculosis (Mtb) lipid composition, with major implications for drug discovery, immunity, and vaccine development. www.nature.com/articles/s41... A thread.
Eachan Johnson reposted
Eachan Johnson reposted
@peterfineran.bsky.social and colleagues develop Tn-seq for phages by leveraging anti-CRISPR (Acr) as a positive selectable marker in the presence of CRISPR-Cas counter-selection, and identify essential genes in phage from non model orgs www.biorxiv.org/content/10.6...
Eachan Johnson reposted
Light-activated metal complexes have been shown to disable antibiotic resistance enzymes in E. coli, significantly enhancing the effectiveness of existing antibiotics without harming human cells. doi.org/hbcxrb
Eachan Johnson reposted
📣 Paper alert! I am delighted that our paper exploring the impact of Neanderthal-derived variants on the activity of a disease-associated craniofacial enhancer has been published in Development today! journals.biologists.com/dev/article/...
🚨Deadline for our Senior Scientist applications is next week. If you want to develop your academic career in London and help us tackle next-generation drug discovery for Gram-negative infections, apply!
📢 We're searching for a PhD-level Senior Research Scientist to develop a next-generation antibacterial drug discovery strategy for Gram-negative infections. If you're looking to combine CRISPRi and high-throughput assays, reach out to me by email or apply below. www.linkedin.com/jobs/view/43...
Eachan Johnson reposted
Crick group leaders work across disciplines, supported by core funding and mentoring to build ambitious, curiosity-driven research. Apply now to join us ➡️ www.crick.ac.uk/careers-stud...
Eachan Johnson reposted
Just a few weeks left to apply for our clinical PhD programme. We're looking for clinicians who are passionate about research to join the 3-year fully funded programme. Learn more and see what positions are available ⬇️ www.crick.ac.uk/careers-and-...
📢 We're searching for a PhD-level Senior Research Scientist to develop a next-generation antibacterial drug discovery strategy for Gram-negative infections. If you're looking to combine CRISPRi and high-throughput assays, reach out to me by email or apply below. www.linkedin.com/jobs/view/43...
Join our community of more than 120 ambitious research programmes in infectious disease, chemical biology, and many other areas of biomedicine - all under one roof with fantastic facilities and support.
We're now recruiting early career group leaders at the Crick to lead ambitious research programmes and explore bold scientific questions. Hear our Director, Edith Heard, explain why the Crick is a unique place for curiosity-driven research. Apply now ➡️ www.crick.ac.uk/careers-stud...
Eachan Johnson reposted
We are inviting applications for postdoctoral fellows in immunology of TB at the South African Tuberculosis Vaccine Initiative, University of Cape Town. For more information see the attached ad: idm.uct.ac.za/media/739223
Eachan Johnson reposted
Eachan Johnson reposted
Important piece from Sarah Stanley at Berkeley on new NIH definitions that can be construed to arbitrarily halt research that is both safe and important to public health and future cures www.statnews.com/2025/10/06/g... via @statnews.com
Eachan Johnson reposted
🧪 Excited to share our new work on reactive metallo-scaffolds (r-mS)! We combine metal complexes with chemoproteomics to discover new liganding sites across the proteome! Shout out to a great collaboration with GSK! Fantastic team effort 🫶🏻 chemrxiv.org/engage/chemr...
📢 PhD Opportunity @crick.ac.uk Want to help fight against antimicrobial resistance? Join us in London! Open to international applicants. We have non-clinical & clinical PhD positions to accelerate antibiotic discovery across bacterial species. November deadlines. More details ⬇️🧵
📆 Deadline: 5 November. Charting an atlas of bioactive chemical space in pathogenic bacteria How can we computationally design experiments to more quickly discover new chemical probes and antibiotics? ✍️ Apply here: www.crick.ac.uk/careers-stud...
📆 Deadline: 14 November. 🩺 Doctoral Clinical Fellows programme (3-year PhD) 🤝 Exciting collaboration with the amazing @jeanninehess.bsky.social Curating bioactive chemical space in pathogenic bacteria using accumulation signatures across species ✍️ Apply here: www.crick.ac.uk/careers-stud...
Eachan Johnson reposted
Our article on human multidomain protein biogenesis is now published in @natsmb.nature.com www.nature.com/articles/s41...
Eachan Johnson reposted
Development does not happen in isolation! Material properties, geometry, stiffness, fluid flows...can all steer how development unfolds. If you’re exploring these kinds of questions, we’d love to see your work @dev-journal.bsky.social More info below ⬇️
📢Call for papers. Submit your latest research to our upcoming special issue – The Extracellular Environment in Development, Regeneration and Stem Cells Guest Editors: Alex Hughes and Rashmi Priya 📅 Deadline: 1 March 2026 journals.biologists.com/dev/pages/ex... #DevBio
Eachan Johnson reposted
Now online! Mining the CD4 antigen repertoire for next-generation tuberculosis vaccines
Eachan Johnson reposted
Be my colleague! Cal Poly San Luis Obispo is hiring two tenure-track positions for Fall 2026, chemical education and coatings technology. Chen Ed: jobs.calpoly.edu/en-us/job/55... Coatings: jobs.calpoly.edu/en-us/job/55...
Eachan Johnson reposted
Please apply to our tenure-track faculty position at @stanford-chemh.bsky.social! We are searching for a new colleague working at the interface between computation and molecular sciences. See post below and pls forward widely! chemh.stanford.edu/opportunitie...
Eachan Johnson reposted
My institution is looking to hire a new microbiologist: apply.interfolio.com/173702. Please share, and let me know if you have any questions about the position or UTA.
Eachan Johnson reposted
So...what would happen to the global TB epidemic if we hypothetically "eliminated" undernutrition? In this preprint, we combined estimates from our new review (doi.org/10.1093/ije/...) with population-specific BMI distributions to find out...(doi.org/10.1101/2025...)
Eachan Johnson reposted
Eachan Johnson reposted
Eachan Johnson reposted
A new methods paper from us, this time with a focus on reliable monitoring membrane potential and cell lysis at different growth stages and cell densities. Also, note the surprisingly high level of background lysis in seemingly healthy B. subtilis cultures. www.biorxiv.org/content/10.1...
Eachan Johnson reposted
Now available in a polished format! An important step toward accelerated functional genomics for the Cryptosporidium parasite. Brought to you by the incomparable @lucy-watson.bsky.social www.nature.com/articles/s41...