Tom Scriba

Super excited to share the cover of my first ever book, coauthored with Derick Haire, a senior talent recruiter! We used our complimentary expertise to produce a 400+ page guide on how one enters the field of global health, and how one navigates careers to achieve impact Details coming soon!!

We're unable to measure our immune system status in the clinic. But that is about to change. Our @nature.com piece today. nature.com/articles/d41...

Hey @gilead.com it’s time to put #PeopleOverProfit and make lenacapavir accessible and affordable for everyone, everywhere! #Lenacapavir #GileadSciences #HIV #TulsaPride

Wow, a tuberculosis test makes the TIME Best Inventions list! time.com/collection/b...

Very pleased to contribute to this meta-analysis. Among contacts of #TB, protection from preventive therapy waned quickly in high incidence settings, but persisted for years in low and medium incidence settings authors.elsevier.com/sd/article/S... @uofgshw.bsky.social 🦠🧪🛟

Most supplements and vitamins have little or no proven benefit, and even some have potential of harm, but that hasn't held back ~80% Americans taking them, highest proportion ever www.nytimes.com/2026/09/11/w...

Now published in @natcomms.nature.com www.nature.com/articles/s41... (open access) #tuberculosis #TB

TB VACCINE | A pivotal clinical trial could pave the way for a new TB vaccine in more than a century. As we await the results, Russell Rensburg argues that it’s time to start preparing for the broader realities of rolling out the jab. www.spotlightnsp.co.za/2026/08/28/s...

😔 Newborn deaths are surging in the world’s most vulnerable communities as aid cuts hit www.independent.co.uk/news/health/...

Really very good news for South African investigators! Though many will remain weary about risks posed by short-term reversals of such decisions, as frequently seen in the last 18 months. NIH lifts ban on funding research in South Africa | Science | AAAS www.science.org/content/arti...

Lab meetings don’t always have to be so formulaic go.nature.com/4qnykGh

Amazing TB vaccine PostDoc opportunities with one of the best in the field. Don't think Rasmus is on here. So thought I'd share like this #TBsky

"Those who believe in free, open, and responsive institutions must recognize how critically linked science is to democracy itself and defend its integrity with every tool at their disposal," writes John Palfrey in a new #ScienceEditorial. https://scim.ag/4i9awDH

Just unbelievable what damage this will do! www.bbc.com/news/article...

Vaccine benefit in children "Since 1974, vaccination has averted 154 million deaths, including 146 million among children younger than 5 years of whom 101 million were infants younger than 1 year." www.thelancet.com/journals/lan... The most striking benefit was for vaccination vs measles (Figure)

www.news.uct.ac.za/article/-202...

Peptide injections are the hottest trend in wellness. Researchers say enthusiasm for these unregulated drugs has got ahead of the science go.nature.com/4wUKtV2

Mid-winter run on the southern slopes of Table Mountain - what a pleasure

Excellent review on the safety and efficacy of mRNA vaccines: a mechanistic and public health perspective - The Lancet www.thelancet.com/journals/lan...

We are looking for an amazing person to join our team as a Project Manager to support me across a portfolio of child and adolescent TB studies. Use the following link su.ac.za/en/careers-su to apply.

IN THE SPOTLIGHT | Globally, childhood vaccines have saved an estimated 154 million lives since 1974. In this special briefing, we detail which vaccines are in used in South Africa. www.spotlightnsp.co.za/2026/07/01/i...

SHINGLES VACCINE | A new, more effective shingles vaccine is finally set to hit the market in South Africa. The vaccine, Shingrix, should soon be available at private sector pharmacies, but availability in the public sector seems unlikely for the time being. www.spotlightnsp.co.za/2026/06/25/n...

Exciting opportunity for a Medical Officer and a Study Nurse to join our research team at the Desmond Tutu TB Centre to work on the newly funded DEFIANT study to evaluate the impact of puberty on host immune responses to Mtb. www.linkedin.com/jobs/view/44... www.linkedin.com/jobs/view/44...

Cape Town Marathon lands Major status in first for Africa

Chronic air pollution exposure (even moderate) and more advanced coronary artery disease pubs.rsna.org/doi/10.1148/...

Perhaps the fact that we are conducting an unprecedented experiment with the only home we have, by digging up and burning massive amounts of fossil fuels that is driving global change at rates 10X faster than the most recent warming of this magnitude that occurred oh about 55 million years ago? 🧐

This BBC article states that "climate change is believed to have played a role in such hot spells as this." Let me fix it: Climate change IS making these hot spells more likely and more dangerous. Scientists have been warning of this for decades. www.bbc.com/news/article...

www.sciencedirect.com/science/arti...

Tuberculosis kills on a vast scale, but as foreign aid shrinks, countries with a high burden of TB stand to gain a lot by investing more to curb the disease and its heavy social cost @economist.com impact.economist.com/health-socie...

SCIENCE AND STRATEGY STAR | Professor Willem Hanekom tells Spotlight about taking a ventilated young patient to the Sea Point promenade, living with HIV, the need for an African research agenda, and the recurring joy that has defined his career. www.spotlightnsp.co.za/2026/05/07/t...

A Review in Communications Medicine explores Long COVID — which affects more than 400 million people globally — including current knowledge, gaps and future directions for research, diagnosis and treatment. go.nature.com/4unyxtI #medsky 🧪

Bangladesh is in the grip of an explosive measles epidemic, stemming from a catastrophic breakdown in vaccine procurement following the country’s 2024 revolution. The result was nationwide vaccine shortages and plummeting immunization rates. https://scim.ag/4tM2lAr

So we blocked IFNγ in Mtb infected macaques and….the animals were fine. Turns out mice overestimate the importance of IFNγ in TB because IFNγ drives iNOS in mice but not macaques or humans. This means we don’t actually know how T cells suppress Mtb. rdcu.be/ff9GB #tuberculosis #immunology

Beautifully done and important trial. An effective mTb test that utilizes tongue swab specimens will be absolutely transformative for Tb diagnosis especially is resource limited settings. Definitely practice modifying. www.nejm.org/doi/full/10....

In this mathematical modelling study, Katherine Horton & co assess #TB community screening approaches & their estimated effects on TB incidence & mortality, concluding that methods that capture both infectious & non-infectious TB are needed to achieve sustained case reductions🧪 plos.io/4tuD2SM

In our latest paper in @plosmedicine.org, we explore trade-offs in diagnostic algorithm, coverage, and duration of community screening for #TB, highlighting the importance of symptom-agnostic approaches and the need for strategies to sustain impact when screening ends. plos.io/4tuD2SM

A fascinating long read for World TB Day #tbsky @stoptb.bsky.social @madhupai.bsky.social @treatmentactiongroup.org @tomscriba.bsky.social

DATA MUST DRIVE ACTION | South Africa's new TB dashboard is a win for transparency. The data must now help boost TB testing and find the people still missing from care, say leading TB activists. www.spotlightnsp.co.za/2026/03/16/a...

NEW HOPE | For more than a century, the world has relied on a single TB vaccine. That could finally change with top South African researchers playing a key role. Associate Professor Angelique Kany Kany Luabeya explains why this moment matters. www.spotlightnsp.co.za/2026/03/17/t...

"When intending to upload code, some researchers have also accidentally published partial or entire Biobank datasets to GitHub, a popular online code-sharing platform." www.theguardian.com/science/2026...

41 Celsius in Cape Town today

We have a vacancy for Data Scientist position within our dynamic clinical immunology group. To apply visit the UCT online job portal at: www.uct.ac.za

Pretty depressing stuff www.nature.com/articles/d41...

Latest research: Estimating the population impact of new tuberculosis vaccines depending on efficacy against infectious asymptomatic tuberculosis: A modelling study appearing in the @plosmedicine.org journal. pubmed.ncbi.nlm.nih.gov/41678562/

#ClimateChange isn’t just melting ice caps. It’s changing pollen seasons, worsening air pollution and increasing breathing problems in South Africa. Learn how to report it accurately — and compellingly. Sign up for our webinar. forms.gle/NTHCHkMnZiG7...