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My book on Epigenetics: History, Molecules and Diseases www.amazon.com/Epigenetics-... #EpigeneticsBook #Epigenetics
John Greally
@greally.bsky.social
Using genomic information to improve medicine
1.9K followers689 following580 posts
Pinned
My book on Epigenetics: History, Molecules and Diseases www.amazon.com/Epigenetics-... #EpigeneticsBook #Epigenetics
In memory of Dónal Lunny, the greatest transition in Irish music history at 2:27. Nothing short of a musical genius, he will live forever. youtu.be/xB07-Cuh4Fo?...
At least this field of very squishy science is talking about being more rigorous. Notable omission -- if you have a phenotype that looks inherited, sequence the genome for a mediating genetic variant. DNA is a really good way of transmitting information between generations.
Online now! Rethinking evidence for epigenetic inheritance in human research http://dlvr.it/TW1Qc5 @lohammer.bsky.social & colleagues @cp-trendsgenetics.bsky.social #ASHG26
@mcuban.bsky.social seems like a good guy. This could be transformative for rare diseases. Mark Cuban wants to crack open the market for rare disease treatments www.statnews.com/2026/10/21/m... via @statnews.com
This sounds like a great opportunity. @institutcurie.bsky.social
Our Dept. of Genetics and Developmental Biology at the Institut Curie in the heart of Paris is hiring a new junior PI. It has a nice start up package and excellent I. Curie facilities. Please spread the word: Deadline Dec. 18th! jpi-recruitment-curie-umr3215-u934.curie.fr
A workshop, not a conference, challenging each other with new ideas and perspectives, thanks to @pablonavarrolab.bsky.social and co-organisers for convening this group in beautiful Baeza in Andalusia. www.unia.es/estudios-y-a...
New Yorkers, look out for Jordan from Clarecastle: "Jordan is described as being about 5ft 7in tall, of slight build, with light brown, shoulder-length hair and a beard. He has blue eyes and a piercing at the back of his neck." www.irishtimes.com/world/us/202...
Profoundly disturbing. When DNA methylation tests meet the garbage wellness industry. Zoltar’s advice outside the old Gem Spa in the East Village was about as valuable, and cost a lot less www.nytimes.com/2026/10/08/s...
John Greally reposted
Last week to apply for this. If you are interested in working on cool project to understand the role of DNA methylation in regulating transcription please apply!
🚨 #Postdoc position open. Want to understand non-canonical #epigenetic regulation of mammalian transcription? Come work @uoe-igc.bsky.social in Edinburgh! We’re looking for a motivated & collaborative colleague with a strong track record. 📅 14 October 2026 📢 Please share Apply here 👇
Tim Bestor has left us. This obituary captures him well — you always had to be at your intellectual peak with him, while his trainees always spoke highly of their experiences. He made a massive contribution to epigenetics, a giant in our field. www.genetics.cuimc.columbia.edu/news/memoria...
From my book, Tim was part of an extraordinarily fertile time of discovery in the field of epigenetics, the period in which the 'genomic biochemists' seemed to be churning out fascinating papers every week. [Book: www.cshlpress.com/default.tpl?...
Maith thú a Chaoimhín! @wiringthebrain.bsky.social
If you have questions about epigenetics - and who does not? - this excellent podcast with @wiringthebrain.bsky.social is a clear, in-depth discussion of what it is, what it is not and why so many experts groan out loud every time "epigenetics" shows up in the headlines. youtu.be/6Ugbm6HJko4
This is a common Bronx story. People there do not deserve to live under such pressure when wealth abounds in NYC www.nytimes.com/interactive/...
One week left to register, Workshop Transcriptional memory in health and disease: www.unia.es/estudios-y-a... 15 speakers, plus only 50 participants, 3 days of sharing of insights and ideas with leaders in the field.
Looking forward to hearing talks from @pablonavarrolab.bsky.social, @leonidmirny.bsky.social, Petra Hajkova, Amanda Fisher, Wolf Reik and others. Located in the ancient town of Baeza in Andalusia in Spain, it should be a beautiful retreat 20-22 October.
John Greally reposted
Probability of Necessity www.medrxiv.org/content/10.6... among people who had the variant and developed the disease, the probability that the disease would not have occurred if the didn't have the variant. Low penetrance variants can have a high PN.
This is the poem highlighted among the gifts from the Irish to the US president today. Ceasefire by Michael Longley. Beautiful. Brings tears to the eyes. youtu.be/PAxNRtTqDLI
Thanks to @jkresovich.bsky.social for hosting me at @moffittnews.bsky.social, where I got to chat with colleagues about how we study ‘epigenetics’ in human diseases. Everything from cellular reprogramming to cell fate to functional non-coding variants. Jake looks ready to meet the challenges!
Congrats to my wife @drgmcginty.bsky.social, who ends up leading everything in which she gets involved! news.weill.cornell.edu/news/2026/09...
Disappointing but not the end of the road, good overview at @statnews.com After failure of Angelman syndrome drug, experts see hope in other experimental therapies www.statnews.com/2026/09/04/a... via @statnews.com
John Greally reposted
A JAX-led study published today in @cellpress.bsky.social of more than 5,000 people is challenging long-held assumptions about cerebral palsy genetics. 🧬🧪
Very proud of @einsteinmededu.bsky.social MSTP student Chynna Smith, just awarded a 2026-2027 ASHG @geneticssociety.bsky.social Scholarship. Chynna is a superstar in the making, working on a polycreodism model of osteoporosis. www.ashg.org/membership/a... Congratulations Chynna!
@tuuliel.bsky.social and I proposed the neo-Waddingtonian idea of polycreodism in our 2017 review: www.nature.com/articles/nrg...
Universally adored. Dolly Parton, on holiday, stops into Páidí O Sé’s pub in Ventry, he gives her his prized All Ireland GAA jersey, and she sings unrehearsed with Steve Cooney (around 6:35). Every time he added a flourish she looked over her shoulder with appreciation. youtu.be/2qXFoNrqi3Y?...
The guitarist is Dr. Steve Cooney stevecooneymusic.com/bio The man in orange is the late Séamus Ó Beaglaoich (Begley), accordionist/fiddler and singer and Cooney’s frequent musical partner en.wikipedia.org/wiki/S%C3%A9...
The host is Páidí Ó Sé, who captained Kerry in Gaelic football to an All Ireland title. He presents Dolly Parton with his jersey from that day. paidiose.com Begley and Cooney playing together, as a bonus youtu.be/hTdKb2rUY_I
Now open access: www.annualreviews.org/content/jour...
Just lovely. Horse racing on Omey Island in Connemara. #Homesick www.nytimes.com/2026/08/15/w...
Really looking forward to participating in this workshop: Transcriptional Memory in Health and Disease (if only because they were courageous enough not to call it 'Epigenetics' in Health and Disease) Great speaker lineup, workshop format, limited to ≤50 participants www.unia.es/estudios-y-a...
I like papers that look simultaneously thoughtful and useful, nice work from Alex Ioannidis and colleagues Multi-ancestry admixture mapping reveals ancestry-associated disease loci in the UK Biobank medRxiv. posted 10 August 2026, 10.64898/2026.08.06.26359859 medrxiv.org/content/earl...
John Greally reposted
Two weeks left to apply!
We're recruiting! An open functional genomics postdoc position at @scilifelab-ngi.bsky.social / my lab / Robert Månsson lab. Top notch environment for technology and applications development in lovely Stockholm. Please spread the word or apply if interested: www.kth.se/lediga-jobb/...
John Greally reposted
Come be our colleague. I have been in this Division for 27 years (4 as a postdoc and 23 as a PI). It is an amazing place to work, collaborate, and be inspired. If you are applying to be an Assistant or Associate Professor this Fall, don't miss this deadline.
Join @FredHutch.org's Basic Sciences Division as an Assistant or Associate Professor and help shape the future of fundamental biology. We welcome applicants whose work will complement, extend, or bring new directions to the division.
I just realised that a couple of lovely people left 5-star reviews on Amazon for my book. I would like it to be known that neither of them was me. Thank you both, very kind of you. www.amazon.com/Epigenetics-... #epigenetics
John Greally reposted
John Greally reposted
I have to admit that I didn’t know, and I even thought the Spanish player Cucurella’s look was quite original, when it comes to his hair, but I was unaware of this: If he let his hair grow , it’s so that his autistic son can easily recognize him when he watches him on TV. Truly, this Spanish team ❤️
Hopefully this will provide a free link to a beautiful piece today by @fotoole.bsky.social (Support your local news media) archive.is/202607210554...
I should post another summary of something from my book. Any requests? I was thinking of an overview about DNA methylation, but open to other ideas. www.cshlpress.com/default.tpl?...
I finally got around to putting together a quick overview of what my book is all about. youtu.be/xPt1xy4_i-o?... #epigenetics #epigeneticsbook #epigenome
John Greally reposted
New NJ law criminalizes interference with trans healthcare share.google/xT0wTeUXv9Bf... Some good news!
John Greally reposted
Very cool. NYC has a map for locating sites providing free N95 masks.