Duncan Sproul

Duncan Sproul

@sproullab.bsky.social

Group leader at MRC Human Genetics Unit, University of Edinburgh. Interdisciplinary research on disease #epigenetics. Part-time solo dad. Occasional music and climbing. https://institute-genetics-cancer.ed.ac.uk/research/research-groups-a-z/sproul-group

3.1K followers3.7K following840 posts

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Very pleased to have been part of this fantastic collaborative project. Read on if you want to know about what DNA methylation changes might be doing in aging.

Dan Sarni@dansarni.bsky.social

What if DNA methylation changes aren’t just ticking of our biological clock but rather the rust breaking the gears? Very excited to share our work - how DNA methylation contributes to stem cell dysfunction and aging, published in @natgenet.nature.com doi.org/10.1038/s415... #epigenetics #aging 1/11

🚨 Looking for a PhD and want to translate mechanistic insights in DNA methylation biology to human development? Great collaboration with @hannahlong.bsky.social and Marcus Wilson. Dissecting DNMT3B functions in human development using human ES cells. 📅 Deadline 16th November 2026

institute-genetics-cancer.ed.ac.ukDissecting DNMT3B functions in human development | IGC Graduate Research & Training | Institute of Genetics and CancerPrimary Supervisor: Dr Duncan Sproul

Duncan Sproul reposted

Suggestions! I have not found many articles (DVS or scholar) on "How to best visualize zero" - a quantity with no dimension. Missing values, yes. See chart below, we do not like the 3D effect, or the annotation? But what is the recommendation? #DataViz 📊 #DataFam

Duncan Sproul reposted

Share your research with a multidisciplinary audience of cancer researchers. Students and early career researchers are invited to submit abstracts for speaking opportunities at Cancer Biology Across Scales, taking place in London on 25-26 Jan 2027. Deadline: 30 Oct 2026.

tinyurl.comCancer Biology Across Scales | Cancer Research UKJoin discovery researchers in London, UK (25–26 Jan 2027) to uncover new perspectives in cancer biology, connect across disciplines and accelerate your career.

Duncan Sproul reposted

Calling cell biology ECRs - the British Society for Cell Biology are looking for new student and postdoc committee reps. Apply now! I guarantee you will learn a lot, meet interesting people AND you get to attend the annual BSCB meeting for free!

British Society for Cell Biology@bscb-official.bsky.social

We are seeking new BSCB committee members! Application deadline extended to 9th November to apply for: · Shadow Science Advocacy Officer · Shadow PhD Representative We also seeking a BSCB PostDoctoral representative. For more information and how to apply: bscb.org/apply-to-joi...

Duncan Sproul reposted

📢 EASTBIO funded #PhD opportunity in our lab at #Edinburgh! Interested in #LiveImaging and capturing fascinating tissue dynamics in vivo through movies like this one? Get in touch to discuss further! Deadline: 16 Nov 2026 Please do share! www.findaphd.com/phds/project... #Drosophila #CellBio #DevBio

Duncan Sproul reposted

Duncan Sproul reposted

Duncan Sproul reposted

Join us online for #Epigenomics26 🖥️ 🗓️ 4-6 November Secure a virtual seat by 26 October👉 bit.ly/3ZTJI0a Hear global scientists sharing insights on the latest genomics tools, technologies, and approaches driving studies into common human diseases. Talks will emphasise clinical application🧬

Duncan Sproul reposted

Join us for the 5th season of Sci.STEPS! We are looking for mentors in all fields of science (academia or not, everyone is welcome!) to help their junior colleagues consciously plan and develop their career.

The call for #mentors for our Mentoring Season 2027 is officially open 🤩 We invite #mentors from varied backgrounds and stages of #scientific careers to apply and share your knowledge and expertise. 📝Register here: www.scisteps.org/more/join-us... 🗓 Deadline: 8th November 2026 23.59 CET.

Last week to apply for this. If you are interested in working on cool project to understand the role of DNA methylation in regulating transcription please apply!

Duncan Sproul@sproullab.bsky.social

🚨 #Postdoc position open. Want to understand non-canonical #epigenetic regulation of mammalian transcription? Come work @uoe-igc.bsky.social in Edinburgh! We’re looking for a motivated & collaborative colleague with a strong track record. 📅 14 October 2026 📢 Please share Apply here 👇

Very cool scheme and chance to work with some fantastic colleagues!

Aga Gambus@agagambus.bsky.social

Our EU-funded MOBILITY fellowships are now open for applications! If you are interested in starting your independent career within Molecular Biodiscovery at University of Birmingham - check out www.birmingham.ac.uk/mobility or join us for webinar - registration on the website! Share please 🙏

Duncan Sproul reposted

Duncan Sproul reposted

Save the date! The 10th Munich Epigenetics Spotlight 📅 30 Oct 2026, 14:00–19:00 at Helmholtz Großhardern. Join us for talks and discussion with keynote speakers Tuğçe Aktaş and Karsten Rippe. Organised by @metorrespadilla.bsky.social and @robertife.bsky.social #EpigeneticsSpotlight bit.ly/4jGd3WO

bit.lyMunich Epigenetics Spotlight MeetingThis annual meeting takes place at Munich (DE) providing an instrumental platform to discuss the recent findings on epigenetics with the local community.

Duncan Sproul reposted

Great session next week! Not to be missed! @paul-villain.bsky.social from our neighbouring lab has a fantastic story

FragileNucleosome@fnucleosome.bsky.social

📢🧬Join us on Wednesday, Oct 7th for the next #FragileNucleosome seminar to hear exciting chromatin stories from Moonmoon and Paul! If you still haven't registered for our series: us06web.zoom.us/webinar/regi...

Duncan Sproul reposted

I think I managed to get 2 first author papers out in a year once during my most productive postdoc period, when I had no teaching or admin. I reckon I’ll be ok 😂 . Very interesting graph though… might need to log the y axis soon 🧪 #academicsky blog.arxiv.org/2026/10/01/u...

blog.arxiv.orgFair Moderation, Equitable Access, and AI: arXiv’s Updated Rate Limit PolicyarXiv, and the scientific community at large, are facing a watershed moment. Scholarly publishing is currently changing at a rapid pace, and we are seeing a…

Duncan Sproul reposted

Great reporting from @robinbisson.bsky.social on an absolutely dire funding situation…

Research Professional News@resprofnews.bsky.social

MRC success rates drop sharply after grants overhaul. Warnings of “catastrophic” impact on medical researchers as some rates fall below 5 per cent. www.researchprofessionalnews.com/rr-news-uk-r...

Duncan Sproul reposted

🚨 Please share! 🚨 I'm recruiting a fully funded 4-year Gatsby Sainsbury PhD studentship at Durham! 🌱🤖 Designing plant immune receptors from scratch, combining AI protein design with structural biology and plant immunity. If you're interested please get in touch! benthamlab.org shorturl.at/U2PdV

benthamlab.orgBentham Lab — Durham UniversityBentham Lab, Centre for Programmable Biological Matter, Durham University. Structural biology and de novo protein design applied to host-pathogen interactions, plant immunity, and neglected tropical d...

Duncan Sproul reposted

We are looking for motivated students to apply for the FPU scholarships to pursue a PhD in 3D genomics and gene regulation in development and disease. If you're interested, please email me: jsantos2@us.es

Duncan Sproul reposted

This week is your last chance to apply for our Principal Bioinformatician role! Check out the advert below to learn more and apply before Sunday, 4th October 👇

📢 We are recruiting a Principal Bioinformatician (NBC/26/34) to join Vsevolod Makeev's Bioinformatics & Biostatistics team! An exciting opportunity for a skilled, highly motivated Computational Biologist in rare cancer research. 👉 Find out more & apply: cruknbc.org/vacancy-prin...

Duncan Sproul reposted

Tim Bestor left us this summer. An extraordinary scientist, epigenetic pioneer, always challenging dogma with a flair for language. For us, above all, he was a generous, loyal, caring and deeply supportive mentor. « Be cool everybody », as he used to saywhen leaving the lab at the end of the day.

Surely one to listen to with interest!

Epigenetics Podcast@epigeneticspod.bsky.social

In this episode we speak with @robklose.bsky.social, Professor of Genetics at the University of Oxford, about how CpG islands help control gene expression and chromatin regulation during development. #podcast #epigenetics Listen here: activemotif.com/podcasts-rob...

Duncan Sproul reposted

Last month to apply for ECR places on our workshop on developmental robustness taking place next April. Apply and spread the word, I promise it’s going to be great!

The Company of Biologists@biologists.bsky.social

Funded places are available for early-career researchers at our Workshop on Bridging Scales and Disciplines to Understand Robust Development, 18-21 April 2027, organised by Mauricio Rocha Martins and Giulia Paci @giuliapaci.bsky.social Find out more and apply at www.biologists.com/workshops/ap...

Had a fantastic time at this yesterday catching up with my fellow PhD program alumni!

Wendy Bickmore@wbickmor.bsky.social

Emotional day yesterday celebrating alumni of the MRC Human Genetics Unit PhD programme across 3 decades. Wonderful to see old friends and hear about the amazing contributions our alumni are making across all walks of life. Closure of this training programme is such a loss. @uoe-igc.bsky.social

Duncan Sproul reposted

Tomorrow! The Physical Genomics Trainee Program Research Showcase featuring talks by PhD students Evelynn Chen and Eric Tong, live on Zoom. Join us! Registration is free at tinyurl.com/pr5nbkf3 #genomics #northwestern #cpge #biophysics #research #chromatin #biology #womenshealth #transcription

Reposting this postdoc opening in our lab. We also now have an opening for a graduate research assistant for the same project. Deadline 23rd October 2026 and details here: elxw.fa.em3.oraclecloud.com/hcmUI/Candid...

elxw.fa.em3.oraclecloud.comResearch AssistantWe are looking for a self-motivated, enthusiastic research assistant to join the laboratory of Dr Duncan Sproul at the University of Edinburgh’s Institute of Genetics and Cancer and support research i...
Duncan Sproul@sproullab.bsky.social

🚨 #Postdoc position open. Want to understand non-canonical #epigenetic regulation of mammalian transcription? Come work @uoe-igc.bsky.social in Edinburgh! We’re looking for a motivated & collaborative colleague with a strong track record. 📅 14 October 2026 📢 Please share Apply here 👇