@AIOpticalBioLab.bsky.social. Group Leader #ITQB & H. Prof #UCL. #Nanoscopy & #AI for #LifeSciences. #SRRF sensei. #ERCCoG, #EMBO member. Dad. Opinions my own
- henriqueslab.org -
🔬🚀 It's out! Run 100s of imaging experiments before touching a microscope. #VLab4Mic reproduces them in silico from PDB/AlphaFold to help you image right first time. From rockstars Damián Martínez & Bruno Saraiva, inaugural preprint of @mariodelr.bsky.social new lab
www.biorxiv.org/content/10.6...
🔬📈 We analysed #microscopy papers to track #bioimage analysis use. ImageJ+Fiji dominate, but others are gaining ground. Researchers undercite them and provide too little detail to reproduce analyses. By Tayla and Bruno, with @guijacquemet.bsky.social lab
📄 doi.org/10.64898/2026.10.21.760457
Checkout our new preprint 🔬! An eye-opening analysis detailing the adoption of bioimage-analysis tools in microscopy, curated with Bruno Saraiva and @henriqueslab.bsky.social – a thread 🧵:
preprint: doi.org/10.64898/2026.10.21.760457
github: github.com/HenriquesLab/mapping-bioimage-software
Last day to apply: our two ERC-funded Master's fellowships close tonight at 23:59 Lisbon time. For 066 (smart microscopy of infection) we are looking for physicists, engineers and computer scientists.
https://euraxess.ec.europa.eu/jobs/472471
Applications close 27 October. Two ERC-funded fellowships let MSc graduates start a PhD at ITQB NOVA in December. Physicists, engineers, computer scientists: one call is yours, building a smart microscope that catches infection live and images it at 20 nm. henriqueslab.org/pages/recruitment.html
Applications close 27 October. Two ERC-funded fellowships let MSc graduates start a PhD at ITQB NOVA in December. Physicists, engineers, computer scientists: one call is yours, building a smart microscope that catches infection live and images it at 20 nm. henriqueslab.org/pages/recruitment.html
🔬🚀 A head start on your PhD! Two ERC-funded fellowships for Master's graduates at ITQB NOVA, Lisbon: seven months in our lab (Dec 2026 to Jun 2027) to start your research and build a strong 2027 FCT PhD application with us.
Apply by 27 Oct 👇
henriqueslab.org/pages/recruitment
#SFBS2026: Time for @henriqueslab.bsky.social to blow our minds with the stunning suite of approaches his lab developed in less than 10 years: (e)SRRF, DL4Mic, SReD, NanoPyx, VLab4Mic. Starting with the legendary SMLM Eiffel tower! henriqueslab.org
Making a request to the void for someone to make a model that diagnoses a car from sound, instead of me beatboxing engines noises to a mechanic over the phone
🔬🚀 A head start on your PhD! Two ERC-funded fellowships for Master's graduates at ITQB NOVA, Lisbon: seven months in our lab (Dec 2026 to Jun 2027) to start your research and build a strong 2027 FCT PhD application with us.
Apply by 27 Oct 👇
henriqueslab.org/pages/recruitment
⚙️ Physicists, engineers, computer scientists (066/BI/2026): build a smart microscope that spots infection events live with neural networks, fixes the cell at that moment with NanoJ-Fluidics and images it at about 20 nm.
euraxess.ec.europa.eu/jobs/472471
🔬🚀 A head start on your PhD! Two ERC-funded fellowships for Master's graduates at ITQB NOVA, Lisbon: seven months in our lab (Dec 2026 to Jun 2027) to start your research and build a strong 2027 FCT PhD application with us.
Apply by 27 Oct 👇
henriqueslab.org/pages/recruitment
🧫 Biologists (065/BI/2026): how do bacteria get into human cells? Study cell entry with a natural model, the midbody remnant, a bacterium-sized particle released at every division, using AI-guided microscopes, and compare it with S. aureus.
euraxess.ec.europa.eu/jobs/472468
This kind of tool (see also Quarto, Jupyter Book, and Manubot) is so cool -- and nicely solves the problem of incorrect values in a manuscript! (cc @casey.greenelab.com )
🚀 Rxiv-Maker is now peer-reviewed and open access! Write your manuscript in Markdown and get a typeset PDF or an editable Word file, with figures, citations and cross-references numbered for you. Led by Bruno Saraiva, with @guijacquemet.bsky.social's lab 🔬
doi.org/10.1242/jcs.265183
🚀 Rxiv-Maker is now peer-reviewed and open access! Write your manuscript in Markdown and get a typeset PDF or an editable Word file, with figures, citations and cross-references numbered for you. Led by Bruno Saraiva, with @guijacquemet.bsky.social's lab 🔬
doi.org/10.1242/jcs.265183
🚀 Rxiv-Maker is now peer-reviewed and open access! Write your manuscript in Markdown and get a typeset PDF or an editable Word file, with figures, citations and cross-references numbered for you. Led by Bruno Saraiva, with @guijacquemet.bsky.social's lab 🔬
doi.org/10.1242/jcs.265183
For quantitative cell biology, the manuscript can carry its own Python or R code. Figures and reported values are rebuilt from the data at every compile, so the text stays in step with the analysis. One command also packages it for arXiv or bioRxiv 👇
rxiv-maker.henriqueslab.org
Thank you to Rita Carlota, António Brito and @ivanhcenalmor.bsky.social, and to everyone who has already written preprints with it and sent us feedback =)
Give it a go: pipx install rxiv-maker
I think I'm going to lose it being lectured on microscopy image presentation integrity by the winner of the Small Artificial World in Motion competition
I think I'm going to lose it being lectured on microscopy image presentation integrity by the winner of the Small Artificial World in Motion competition
What if any dataset, any size, any number of dimensions, opened in a browser tab from a link? 🔬🧪💻
Luxar is out today: write it in Python, share it as a link, explore it in any browser. Open source. 🧵 @biohub.org
Preprint: doi.org/10.5281/zen...
Code: github.com/royerlab/luxar
This is the updated part. Looks like the movie is an AI-generated fluorescence image from a non-labeled acquisition technique. No indication that the Small World jury and organizers have requested and verified the raw data (as mentioned as a possibility in the competition rules)
Nikon's response to me on Linked in: "We’ve updated our detailed article with insights from the winner, which may answer some of your questions. We encourage you to check out the link to dive deeper into the technical details" 1/n
www.nikonsmallworld.com/masters-of-m...
🔬 VLab4Mic explores this in silico, connecting molecular models with super-resolution experiment design.
#Microscopy#SuperResolution#VLab4Mic@aiopticalbiolab.bsky.social
🔬🚀 It's out! Run 100s of imaging experiments before touching a microscope. #VLab4Mic reproduces them in silico from PDB/AlphaFold to help you image right first time. From rockstars Damián Martínez & Bruno Saraiva, inaugural preprint of @mariodelr.bsky.social new lab
www.biorxiv.org/content/10.6...
🚨Our work #ReScale4DL: balancing pixel and contextual information for enhanced bioimage segmentation, with @henriqueslab.bsky.social is out today!🚀
www.nature.com/articles/s41...
ReScale4DL links key concepts in DL (receptive fields)+microscopy (resolution) so they can work #bettertogether😉
Threat👇
Can light build centrosome-like activity? 💡🔬
Yes! We introduce LISA (Light-Induced Spindle Assembly), now in @emboreports.org. By clustering Aurora A with optogenetics, we build centrosome-like activity that nucleates microtubules and rescues spindle defects after centrosome loss. shorturl.at/9h3VQ
🔬🚀 Out now in Communications AI & Computing: mAIcrobe, our open-source napari plugin for high-throughput bacterial image analysis. Segmentation, morphological profiling and cell cycle classification, all in one place 👇
doi.org/10.1038/s44488-026-00022-y
Led by António Brito and Bruno Saraiva, with Dominik Alwardt, Beatriz de P. Mariz, Sérgio Filipe and @pinholab.bsky.social, at @itqbnova.bsky.social. Built on @napari.org: StarDist, Cellpose and U-Net, plus a retrainable classifier =)
We put it to work on antibiotic phenotyping in E. coli and on cell cycle defects in S. aureus DnaA mutants. It grew out of eHooke, our old S. aureus pipeline, now opened up to rods, cocci and whatever else you image.
pypi.org/project/napari-mAIcrobe
🚀🔬 Can cell shape, signal and movement tell us about a cell's future? #DeepLearning studies now predict cell fate from #microscopy. Together w Rita, @mariodelr.bsky.social, @inesmcunha.bsky.social, @juliettegriffie.bsky.social + @guijacquemet.bsky.social👇
www.preprints.org/manuscript/202607.1414/v1
Can a cell’s shape and movement reveal what it will do next?
A new Henriques Lab review explores how AI uses time-lapse microscopy to predict cell fate, while asking whether models predict the future or detect changes already underway.
www.preprints.org/manuscript/2...
Ultrafast 3D imaging just got faster! Introducing: "Instant dual-view Snouty (iDV-Snouty) light-sheet microscopy"
-> Double the data rate of a Snouty microscope by adding a 2nd view! Use the extra view for a variety of imaging modes!
Article here: amsikking.github.io/idv-snouty_l...
We're thrilled to unveil our fantastic line-up of selected speakers for SMLMS 2026 at smlms.org Huge congratulations to them! 🎉
Missed the deadline? Good news! Registration and poster abstract submission have been extended until 31st July! 🔬✨
Segmenting individual cells in microscopy is much easier these days thanks to foundation models. Can we use these models for other tasks, such as cell classification? We investigate in our latest work, finding big improvements for object and pixel classification compared to classical approaches.
New preprint! Using multiscale ExM/OPM/ASLM, we show that oncogenic drivers leave distinct 3D architectural fingerprints in intact liver tissue: NRAS primarily remodels cell shape, whereas CTNNB1 shifts mitochondrial architecture toward a pericentral-like state. tinyurl.com/kepy33m6
Our paper is now featured in focal plane! Check it out if you're looking for a platform to predict and plan imaging experiments before entering the microscope room! Very proud to be a part of this project - biggest congratulations to the team @henriqueslab.bsky.social who made this happen 🔬🛠️
Timely callout to #RxivMaker. With rxiv-maker you write in Markdown and the tool generates the LaTeX, so author comments and to-do notes never reach the source files you upload to arXiv. We built it for easy writing with amazing formatting, avoiding this leak is a welcome side effect
Passwords, GPS coordinates and private conversations have all been found in the metadata and source files of millions of preprint submissions
go.nature.com/4fwKh7B
Nuclei as constellations 🔭 #NucleiSky aligns microscopy images across modalities and scales by reading nuclei like stars to map between them. Joy to contribute, led by @ivanhcenalmor.bsky.social and @guijacquemet.bsky.social's team. #RxivMaker powered preprint. Check it out!
Delighted to share our latest preprint "NucleiSky enables cross-scale multimodal registration of microscopy data using nuclei constellations"
www.biorxiv.org/content/10.6...
Code and App: github.com/CellMigratio...
Interested in single molecule localisation microscopy? 🔬 Don't miss #SMLMS2026, hosted in by SciLifeLab, KTH and Stockholm University, with contributions from our Swedish NMI Node colleagues!
🗓️ August 26-28 in Stockholm 🇸🇪
More⤵️
smlms.org