David Tomaz, PhD

🔬 Two research fellowships at Henriques Lab, ITQB NOVA, Oeiras: cell biology or smart microscopy—a head start towards a PhD! Master’s degree by 30 Nov 2026, final grade ≥14/20. Apply by 27 Oct: henriqueslab.org/pages/recrui... @aiopticalbiolab.bsky.social #PhD #Microscopy #CellBiology #ITQB

Top 15 pharma firms: ~$161bn profit in 2025. Their Cali Fund contributions: $0. Total raised in 18 months: $7,085, all from three small firms. Shame. Pay your share. 🌿 #COP17 #COP17 #CaliFund #Biodiversity #Conservation #ProtectNature #Climate #Nature www.theguardian.com/environment/...

Vera C. Rubin has spotted 2026 ED138 beyond Pluto, hidden among the Milky Way’s crowded stars 🪐 #Astronomy The New York Times · www.nytimes.com/2026/10/27/s...

Tumour DNA disappearing from blood tracked with longer event-free survival in NeoCOAST-2. A useful risk signal 🧪 doi.org/10.1038/s415... #Immunotherapy

A historic victory against entrenched power—and a reminder that organised citizens can change what seemed impossible ✊ www.bbc.co.uk/news/article... #Serbia

Describe a protein's job, then test the designs. Pinal generated candidates from text, with functions demonstrated across four protein classes. Not every design works: screening still matters. 🧩 doi.org/10.1038/s415... #ProteinDesign #AI

Less-differentiated T cells may matter for CAR-T durability. Across lymphoma trial cohorts, more naive-like cells in the infusion product tracked with longer disease control 🧬 doi.org/10.1038/s415... #CART

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Debate the percentages. Show us the annual funding commitments for AI²’s 2027–2031 programme. You can’t plan five years without knowing what you can count on. expresso.pt/opiniao/2026... #Science

We've just updated our 2027 EMBL Annual Poster with even more events 🧪 Have a look and tell us which course or conference you're excited to join: s.embl.org/2027-poster @embl.org @ebi.embl.org @embo.org

Applications close 27 October. Two ERC-funded fellowships let MSc graduates start a PhD at ITQB NOVA in December. Physicists, engineers, computer scientists: one call is yours, building a smart microscope that catches infection live and images it at 20 nm. henriqueslab.org/pages/recruitment.html

Being creative and feeling creative aren't the same thing. Adults outperformed preschoolers on creative tasks but felt less confident 🎨 #Creativity www.theguardian.com/science/2026...

RAYE wins the Mercury Prize for This Music May Contain Hope. Some good news to turn up loud 🎶 www.theguardian.com/music/2026/o... #RAYE #MercuryPrize

Seeing others break rules increased rule-breaking in an online experiment—especially among political allies. No penalties were imposed: context matters. 🍎 @lucasmolleman.bsky.social www.theguardian.com/science/2026... #Psychology

Radical Numerics reports giving AI-designed phages—bacteria-killing viruses—to one patient under compassionate use. No clinical outcomes disclosed; not peer reviewed. 🦠 #PhageTherapy www.nytimes.com/2026/10/20/s...

Elizabeth Holmes is back on screen. Have we become better at separating scientific evidence from a convincing sales pitch? Charisma isn't validation. 🎭 #Theranos www.theguardian.com/science/vide...

More activation ≠ better killing. In vitro, TCR engagement on a separate target diverted cytolytic granules and weakened CAR-mediated killing. Spatial context matters. Preprint from @kischober.bsky.social 🔬 doi.org/10.1101/2025... #CART #TCR

Can you understand someone without excusing them? A24’s Holmes doc asks who controls the story and whether the camera reveals or builds it. Integrity isn’t optional. Science sold as a fairy tale helps no one. Yet to watch 🎬. a24films.com/films/you-ca... #Documentary #Dropout

SERPINA3 can activate SIRPα and suppress SIRPα+ immune cells, including NK cells. Blocking it reduced tumour growth in preclinical models 🧬 doi.org/10.1038/s415... #NKCells #Immunology

Enormous news. A melanoma vaccine, one of the most deadly cancers out there. Science is good and helpful and there should be more of it. www.washingtonpost.com/health/2026/...

Neutrophils are not one uniform population. A new atlas combines ~1 million cells from 781 samples to map states across health and disease. 🗺️ doi.org/10.1038/s415... #Immunology

Antibody diversity also depends on keeping germinal centres apart. In mice, weakened confinement let dominant B-cell clones spread between centres and narrow the repertoire. 🧭 doi.org/10.1038/s415... #Immunology

Unfortunately, delaying the report won't delay the warming. Release the evidence available in time to inform decisions. 🌍 #ClimateScience

Can AI change the timeline of mass extinctions? OneStrata reconstructs biodiversity from millions of fossil records, suggesting some declines were more diffuse. Conference findings 🦴 www.nature.com/articles/d41... #Palaeontology

Edited NK cells reach an early human trial: one objective response among nine patients receiving NK510 plus PD-1 blockade, with no dose-limiting toxicities observed. 🔎 doi.org/10.1007/s002... #NKCells

T-cell access is also about location. In mouse melanoma, ICAM-1 blockade redistributed CD8 T cells and improved tumour control with anti-PD-1. 🔍 doi.org/10.1038/s443... #Immunology

NKG2D overexpression gave CAR-T cells extra costimulation from tumour ligands ⚙️ #CART #Immunology #NKcells @labwaggoner.bsky.social

🌊 Of 774 reef-building coral species assessed, 340 were classified as threatened. The analysis uses coral-cover proxies and projected heat stress—not a timetable for extinction. Conservation also means limiting warming. doi.org/10.1038/s415... #Biodiversity

In microscopy, “AI was used” tells us very little. Was it denoising, reconstruction, or generating new content? The raw data and processing steps matter more than how convincing the final image looks. 🔍 #Microscopy #AI bsky.app/profile/natu...

Macrophages mix and match functional programmes—from inflammation to tissue maintenance. #Immunology

ESA/Webb (@esa.int) images (Aug 22, 2022) Jupiter's dynamic atmosphere, including storms and auroras, along with its faint rings, is revealed in this #NASAWebb NIRCam image. esawebb.org/images/jupiter-auroras2/

🧬 Predicting a protein structure is one thing. Designing an enzyme that actually works is another. doi.org/10.1038/s415... #ProteinDesign

🧬 Same STAT3, different NK-cell response. In mouse CMV infection, IL-15 and type I interferon redirect STAT3 towards different gene programmes. Cytokine context matters—not simply switching a pathway on or off. doi.org/10.1126/scii... #NKCells

🧬 Could CAR-NK cells be engineered inside the body? Targeted lipid nanoparticles delivered CAR mRNA and showed activity in mouse models, including humanized blood-cancer models. Promising delivery research—not a human trial. doi.org/10.1038/s415... #CARNK #immunotherapy

Rightly put, and more relevant now here in Europe too, with all the recent events. They want us tired, scared and alone. So the quiet resistance is exactly this: keep looking after each other, keep laughing, keep showing up. Fear only wins if we let it take everything. ✊🤍💙♥️ #Democracy #humanrights

🌿 Closer to the 30% land-conservation target than we thought, but still far from solving the problem. Human pressure doesn’t stop at conservation boundaries, and counting hectares isn’t the same as protecting the life within them. #Biodiversity #Conservation

🧬 Light, chemistry and antitumour immunity: nanoparticles use near-infrared light to disrupt tumour metabolism and trigger immune responses in mice. An intriguing connection—but still preclinical. doi.org/10.1126/scia... #Immunology #CancerResearch

🧬 Receptor geometry matters. An engineered IL-10R agonist made signalling TYK2-dependent, favouring myeloid suppression over T-cell activation in preclinical tests. doi.org/10.1038/s415... #Immunology

🔬🚀 A head start on your PhD! Two ERC-funded fellowships for Master's graduates at ITQB NOVA, Lisbon: seven months in our lab (Dec 2026 to Jun 2027) to start your research and build a strong 2027 FCT PhD application with us. Apply by 27 Oct 👇 henriqueslab.org/pages/recruitment

🧠 Beyond weight loss: a 26-week trial in 108 adults with alcohol use disorder and obesity found semaglutide reduced heavy-drinking days versus placebo, alongside CBT. Promising—not evidence for social outcomes yet. doi.org/10.1016/S014... #GLP1

Oh, the person with the most votes wins? What a wonderfully straightforward idea. Hmm. I wonder how other democracies manage such a radical concept 🙃 #MostVotesWins

Amazing possibilities, with reasons for both hope and caution. Maths today - but which scientific fields will soon follow? This feels like just the beginning. Brace ourselves 🌊 www.science.org/content/arti... #AI #Maths #Science

🌍 Immunology education is also about who gets to participate. A new Nature Immunology Comment discusses locally grounded training, mentorship and cross-border collaboration. doi.org/10.1038/s415... #Immunology #ScienceEducation

I find this so wholesome!!! Nobel-winning science, a very human moment. Karl Deisseroth telling his children the news is such a joy to watch ❤️ www.theguardian.com/science/vide... #NobelPrize #Science

🌙 Five moons in one view: our Moon and Jupiter’s four Galilean satellites. NASA’s APOD explains this striking alignment, captured as a series of exposures. science.nasa.gov/image-articl... #Astronomy

🧬 Immune aging is not just chronological age. A human atlas links CD8 memory-cell states to health trajectories; UK Biobank associations used a protein-based proxy, not direct cell counts. doi.org/10.1016/j.im... #Immunology

🧬 A new LAG3 review examines tonic signalling, ubiquitination-dependent switches and proximity to the TCR. Understanding checkpoint mechanisms goes beyond identifying their ligands. doi.org/10.1038/s415... #Immunology

Breaking News: The Nobel Peace Prize was awarded to Navi Pillay for her efforts to ensure that war crimes and genocide are prosecuted.

🐙 A little late for #WorldOctopusDay, but two favourites worth sharing: "Remarkably Bright Creatures" and "My Octopus Teacher" 🎬 One film, one documentary—both lovely. I really recommend both. A little wonder for your watchlist. #Octopus #Film #Documentary