Only two weeks left to apply for #ResearchFunding and join us in Ridgefield, Connecticut. Establish your own group and receive 890k USD/year for up to 5 years, access cutting-edge infrastructure! career.bmedx.com/call/2025-RD... #ScienceWithImpact #Ophthalmology #TissueEngineering #Biotherapeutics
John Lindner
John Lindner
@johnmlindner.bsky.social
Molecular Immunologist TCRs, BCRs, and their ligands Head of Immunology Discovery at BioMed X Heidelberg, Germany and New Haven, CT
1K followers224 following23 posts
Do you have expertise in one or more of the following areas? #Ophthalmology #organotypic models #TissueEngineering #proteinengineering Just over one month left in our newly opened call for applications to a new research group in Ridgefield, Conn.! career.bmedx.com/call/2025-RD... #ResearchJobs
Our latest call for applications is now open! Early-career researchers in the fields of biotherapeutic engineering, ocular models, and assay technology are invited to join our Ridgefield, Connecticut location as part of an exciting new team! career.bio.mx/call/2025-RD...
Blending my personal and professional lives a bit here, but this is a great short read (and cool "then vs. now" perspective) on a rising star in a related field: Chemists amid coronavirus five years on: @grynova.bsky.social www.chemistryworld.com/opinion/chem...
John Lindner reposted
My lab is hiring a research assistant. If you love culturing cells but wish they weren't so flat, come bioprint with us: we culture in spheres! We culture in cubes! We culture in bioprinted vessels! www.linkedin.com/jobs/view/41...
John Lindner reposted
EFIS mourns the passing of Fritz Melchers www.efis.org/news/fritz-m... We extend heartfelt condolences to Fritz Melchers' family, friends, colleagues and the immunology community around the world. Photo credit: Jacqueline Hirscher
To any and all affected scientists @altnih4science.bsky.social (or other opportunity-seekers), we're hiring in New Haven! Postdoc and RA position, please reach out to me or PI @anothercutler.bsky.social if interested, immunology/macrophage experience ideal, please share with your networks #immunosky
John Lindner reposted
Fantastic News & Views article Nature Portfolio by @michelalocci.bsky.social & @sapostolidis.bsky.social, highlighting our recent study on mRNA vaccines and SLE, its findings, and the key questions to address next! rdcu.be/d4332 #immunosky #SLE #mRNA #Bcells 🦠 👩🔬 💉
Not my work but I wish it was… general advice is to avoid buzz phrases like “tour de force” but let’s make an exception here and compliments to the authors for the precision in the title! Thanks @anothercutler.bsky.social for the heads up www.cell.com/cell/fulltex...
I’m biased of course but this is a detailed new mechanism for the direct action of IL-2 on antigen-experiencing B cells, driving early/extrafollicular antibody responses! Congrats to @katyely.bsky.social and all co-authors on a job diligently and well done! Glad I could help #immunosky #bcells
✨ Ever wondered why B cells are so fond of IL-2? Wonder no more! Our study is now published in Immunity @cellpress.bsky.social 🔍📑 A truly perfect Thanksgiving gift! 🧑🔬💉🔬https://authors.elsevier.com/c/1kAq43qNrUxuTR
🙋♂️ Is IL6R D358A also protective against fibrotic progression?
🚨 Delighted to share our paper defining a new role for IL-6 in TB. 🚨 We used genetic variation to show *reduced* IL-6 signalling is causally associated with *lower* risk of TB. Lead author @gushamilton.bsky.social #TBSky #IDSky #ImmunoSky www.thelancet.com/journals/lan... Thread 👇 (1/8)
Super cool repository, free for (non-commercial) use and still… should never, ever, under any circumstances be used in a PowerPoint presentation sound-effects.bbcrewind.co.uk/search?resul...
Kids, drugs are bad, don’t do them… also, learn to play the cello… also, forget the first part of what I said… you know what, just google “cello goblin” youtu.be/ucWTdsxL25E?...
Indeed a fascinating new look at intratumoral T cell subsets! Would be great to learn about TCR clonality of “Subset 3” and whether these cells are (pre-)enriched for tumor specificities! #immunosky
I’m very fascinated about this study showing stem cell-like effector CD4 T cells that can become the classic T helper subsets. In tumors, Tregs suppress these cells, blocking Th1 seeding and anti-tumor effects! Jenkins lab also recently described a similar CD4 phenotype with different implications.
Agree 💯 and will add that the only substantial way to make those models better at this point is to increase the quality and quantity of training data, which for us only happens in the wet lab
Every day a new foundation model drops, and as an experimentalist, I just skim the preprint and go back to my pipettes. Foundation model fatigue. The bar for adoption is high and requires experimental validation.
John Lindner reposted
next #globalimmuno talk is on this Wednesday, November 20th at 9am PST, noon EST, 5pm GMT by Dr. Padmanee Sharma. Title: “Mechanisms of Response and Resistance to Immune Checkpoint Therapy” LINK: ucsd.zoom.us/j/91053505061 Current schedule : www.globalimmunotalks.org/schedule
As part of my role as Head of Research for US-based BioMed X teams: Alicia Cutler's Team CHM (based in New Haven, CT) is #recruiting an #immunology expert (postdoctoral fellow) to study the role of #inflammation in #vasculature using unique, complex, 3-D models: career.bio.mx/call/2024-NH...
John Lindner reposted
We strongly suggest that academic publishers and other platforms that host research rapidly implement a Share to Bluesky button for their articles. Here's how: docs.bsky.app/docs/advance... #AcademicSky #HigherEd #Altmetrics
John Lindner reposted
John Lindner reposted
NIAID releases alternative to BioRender, all illustrations freely available in public domain bioart.niaid.nih.gov
Happy to have played a (small) role in this study, thanks @katyely.bsky.social for the opportunity to collaborate! Great read on the effects of #autoimmunity on #covid #vaccination!
Our study just out! "Disease-associated B cells and immune endotypes shape adaptive immune responses to SARS-CoV-2 mRNA vaccination in human SLE". 🔗 * rdcu.be/dZWI9 * lnkd.in/desv-ZrV #SLE | #Autoimmunity | #mRNAvaccines | Disease-associated #Bcells shape anti-vaccine immunity in SLE. 👩🔬 💉💉💉 🦠
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