Joel Topf

Joel Topf

@kidneyboy.bsky.social

Saying the product of the kidneys is urine is like saying the product of a factory is pollution. Urine is a by-product. The product is homeostasis. COI: https://pbfluids.com/about/

7.6K followers821 following27.6K posts

Joel Topf reposted

Swapnil Hiremath 🍁🇨🇦
@hswapnil.medsky.social

You want a ticket to the hottest event of #KidneyWk? www.nephjc.com/news/2026/9/... Consider a donation to the fall #NephJC pledge drive

nephjc.com2026 NephJC Night in Denver — NephJCOn FRIDAY night, October 23rd, NephJC will host another legendary NephJC Night during ASN Kidney Week
Nephrology Journal Club@nephjc.bsky.social

#NephJC runs on community magic ✨ We choose to stay free and independent and give back to our community for 12yrs 🩵 If our blogs, podcasts, or visuals have helped you, your donation keeps us going - and might get you into the coolest #KidneyWk party www.nephjc.com/news/2026/9/...

nephjc.comNephJC 2026 Fall Pledge Drive — NephJCHelp keep NephJC a vital, original, and unbiased source of medical education.

Joel Topf reposted

Swapnil Hiremath 🍁🇨🇦
@hswapnil.medsky.social

Took us more than 10 years to get this to this stage AVF versus catheters - doing an RCT was difficult and we learnt a lot. Hope our community also does?

journals.lww.comComparing Catheters to Fistulas in Older Patients Starting... : Journal of the American Society of Nephrologyrecommendations were based is observational with potential for bias. Methods A pilot randomized controlled trial was conducted in 12 hemodialysis centers in Canada and Australia. Individuals aged 55…

Joel Topf reposted

Nephrology Times
@nephtimes.bsky.social

🔗https://www.docwirenews.com/post/era-congress-recap-part-1-find-ckd-and-majesty-trials 🎯Don't miss the two-part conversation between Neph Times board members @kidneyboy.bsky.social and @annagaddy.bsky.social on research highlights from this year's ERA Congress. #nephrology #ERA26

docwirenews.comERA Congress Recap, Part 1: FIND-CKD and MAJESTY Trials | Docwire NewsDrs. Joel Topf and Anna Gaddy discussed highlights of the 63rd European Renal Association Congress, including the FIND-CKD and MAJESTY trials.
Joel Topf
@kidneyboy.bsky.social

This is horrible. The IRB failed in the most basic RCT question, "Would you feel comfortable if your miserably nephrotic grandmother was randomized to the placebo group."

Swapnil Hiremath 🍁🇨🇦@hswapnil.medsky.social

Agree - it would likely be a N of 1000 + trial, and one would need funding of Ritux for control + Obi for intervention. Also, note when Tac was stopped per @brycebarr.bsky.social above! www.kireports.org/article/S246... from Ruggenenti et al in @kireports.bsky.social with same thoughts #ERA26

kireports.orgCritical Reappraisal of Obinutuzumab Randomized Trials in Membranous NephropathyWe read with interest the commentary to our work by Giri et al, (1) and particularly their reference to the MAJESTY trial and its potential implications for the evolving therapeutic landscape of prima...
Joel Topf
@kidneyboy.bsky.social

I bet this was a central IRB selected and paid by the investigators. And they knew that if they played hard ball they would be bypassed for a different, more morally lax, IRB

Joel Topf
@kidneyboy.bsky.social

I subscribe

Nikhil Shah@drnikhilshah.bsky.social

#AudioScholar #Nephrology — a weekly #podcast briefing of the most significant peer-reviewed, citation verified, nephrology literature. Generated by AudioScholar at audioscholar.cc. Podcast Links Spotify bit.ly/4dWr7qU Apple apple.co/4u2YePu RSS feed for ANY podcast app - bit.ly/43aJTpp #FOAMed

Joel Topf reposted

Timothy Caulfield
@caulfieldtim.bsky.social

"...this review found little to no benefits from use of calcium, vitamin D, or combined supplementation on the prevention of fractures and falls." www.bmj.com/content/393/... via @bmj.com

bmj.comCalcium, vitamin D, or combined supplementation to prevent fractures and falls: systematic review and meta-analysisObjective To assess the effect of calcium, vitamin D, or combined supplementation on fractures and falls in adults. Design Systematic review and meta-analysis. Data sources Trials included in system...

Joel Topf reposted

🪾santiago, phd 🐈‍⬛
@santiagokique.bsky.social

Dr. Fauci came to Stanford for Medicine grand rounds and shared a few reflections I thought were worth passing on: The first was about Operation Warp Speed and the current state of the NIH. As you’ll recall the first mRNA vax was developed at record speed. Fauci atttributes that success to 4 factors

Joel Topf reposted

Ben Collins
@bencollins.bsky.social

Replying to @bencollins.bsky.social

If I told you ten years ago all of the Jeopardy winners, doctors, lawyers, stat-focused sports nerds, and premium shitposters escaped Twitter on a pirate ship to a website that was completely inhospitable to Nazis and phrenologists……. I don’t know, man, I’d be pretty excited.

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Joel Topf
@kidneyboy.bsky.social

The final position of the pro-PLEX group was let’s do another randomized controlled trials trying to plug the holes of PEXIVAS #NephMadness #NKFClinicals

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Joel Topf
@kidneyboy.bsky.social

PLEX is not a silver bullet in the treatment of AAV The guidelines have evolved overtime But the guidelines do not provide graded recommendations, only practice points #NephMadness #NKFClinicals

Joel Topf
@kidneyboy.bsky.social

Here is the groups final rec except for the caveats which includes everyone with diffuse alveolar hemorrhage and CRRT And that was for the no PLEX team. #NKFClinicals

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Joel Topf
@kidneyboy.bsky.social

We are taught to objectify patients. We put them in a box with a name which we use to treat them. The cadaver lab is an early example of objectification

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Joel Topf
@kidneyboy.bsky.social

Topol suggested that radiologists should pivot from reading films, that would be a job AI would take over, and instead go talk with patients about the interpretation. This image is what this would look like. Radiologists chose the profession to be away from patients. #NKFClinicals

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