Nick Mark, MD

If you like sci-fi read Hyperion. Trust me. It’s great!

@thelancet.com sums it up in one sentence:

🔥 Hot take: The Pentagon has essentially announced that Claude is so much better than other models that they must have it. Anthropic has signaled that they so much more principled than their competitors, that they can’t. When the Pentagon backs down or loses this is a huge PR win for Anthropic.

Important ECG pattern for trainees to know and recognize, particularly at this time of year.

Thrilled to join @nickmark.bsky.social and @askinforair.bsky.social to talk about managing the RV in the ICU YT link here youtu.be/Supq1q7J28w?... Also on your fav podcast platforms

As you can see from the screenshot we had no fun at all catching up!

Ok added another mock brand ICU shirt: Just Tube It. Which is is your favorite?

Just purchased a norepi shirt! FYI for others interested, the website has additional color options

Added some new “mock brand ICU merch” to the @criticalcaretime.bsky.social store & I think it’s pretty awesome! www.criticalcaretime.com/shop

@nickmark.bsky.social

It's that wonderful time of year when new residents are joining the ICU team! Here are a few of my favorite @criticalcaretime.bsky.social infographics to help you understand key concepts: ⚡️Undifferentiated shock 💉 Vasopressors 😮‍💨 The physiologically difficult airway & 🧪 Metabolic acidosis

Vinay Prasad’s appointment to lead the FDA’s CBER division is a disaster for biotech stocks but it’s worse for patients who depend on new therapies. Therapies that Vinay has signaled he won’t approve.

You have been christened

I work with the best team! Love this battle of the inotrope education: milrinone vs dobutamine. Blue 🔵 or 🔴?

Me: ohh is this chylothorax? Student: who’s Kyle Thorax? Me: obv my new pseudonym..

Is this a ratatouille situation? It would kinda explain a lot.

We talk a lot more about how to put an ETT *IN* than how to take em *OUT*. On this week's @criticalcaretime.bsky.social @askinforair.bsky.social & I talk all things EXtubation. - readiness to exubate - breathing trials - overcoming challenges - addressing cuff leak - plus cases Give it a listen! 1/

I really liked Season 1 of Fallout. One thing that struck me as unrealistic was Vault-Tec’s evil plan: to literally nuke the entire world so they could fundamentally reshape society according to their twisted views. Anyway, it feels pretty realistic after this week…

NIH has rescinded its scientific integrity policy. Hard to see this as anything other than clearing the way for shoddy research on things like vaccines. Regardless of the rationale, it's bad news for public health. grants.nih.gov/grants/guide...

Pretty strong personal statement tbh

🥇 Achievement unlocked! Not only is @criticalcaretime.bsky.social the #1 critical care podcast, we’ve surpassed RFK Jr’s misinformationcast in the rankings.

This is the pinnacle of good design.

Person A submits an article. Person B reviews it & rejects it. Then person B changes the author name & submits the article to a different journal where it’s accepted. He claims he attached the wrong file by mistake. 😝 Really great argument for pre-prints! retractionwatch.com/2025/03/06/p...

So the emotional crux of this week’s Severance involves Ms Corbel suckling at a deflated endotracheal tube?

Prediction: in a year when everyone is lamenting the #DogeRecession, Trump will be looking for someone to blame. Musk is an obvious choice.

Yikes. Starship tumbling out of control & losing engines.

They're going to destroy the Department of Veterans Affairs, specifically the VA healthcare system. Firing this many employees will render it effectively unusable by increasing patient wait times to the point of uselessness.

Atlanta Fed forecasts a -2.8% GDP growth for this quarter. 4 weeks ago it was +3.9%. Trump owns this. bit.ly/3Ddsxim

This may be one of the best forwards to a textbook ever. Very on brand for OB to include the weight & volume of the text…

Is funding for point of care ultrasound (POCUS) endangered because of the anti-woke crusade against “POC”? www.propublica.org/article/ted-... Truly we are living in the dumbest timeline…

I say again: any Republican in congress with an ounce of integrity would switch parties immediately. They are complicit, sadistic cowards. Every single one.

The US is experiencing the largest measles outbreak including the first deaths from the disease in decades. RFk Jr - the newly confirmed HHS secretary - believes that this is a big pharma hoax & measles isn’t a deadly disease. We are so screwed.

Musk & his underlings suspended PEPFAR payments despite orders from SecState & the White House to resume them. Suspension of PEPFAR will cause over 14,000 otherwise preventable deaths. pepfar.impactcounter.com After his inevitable split with Trump, Musk & co should be held accountable for this.

Periodic reminder that for most people with vasodilatory shock we should be targeting a MAP > 60 mmHg (not 65). A lower MAP goal was associated with a shortened duration of vasopressors & possibly reduced mortality. With vasopressors, less is truly more. jamanetwork.com/journals/jam...

I'm with pulmonologist @nickmark.bsky.social on this—What did members of Congress do last week? What has your congressional rep and senator voted for or against? Check their voting record vs what they say on social media or cable news about helping their constituents. #medsky

Thanks for coming on the show for such an important discussion #Pulmonology #MedEd #FOAMed @pulmcrit.bsky.social @pulmtoilet.bsky.social @cardionerds.bsky.social @criticalcaretime.bsky.social @nickmark.bsky.social

THREAD: Trump's intentionally flooding the news cycle w/ a stream of outrage porn to distract, scare, & confuse. These are the stories that actually matter that you might've missed this week: NIH funding cuts jeopardize ‘life-saving’ research in AL aldailynews.com/nih-funding-...

In just weeks, the Trump/Musk administration’s suspension of PEPFAR has already led to thousands of additional cases of HIV that would have otherwise been prevented. DOGE is essentially the opposite of EA; maximizing harm for trivial/non-existent savings. www.wired.com/story/usaid-...

NEW: Medications for HIV treatment and prevention were supposed to resume around the globe. But they haven't, multiple sources told me. Not only are there basically no employees left to carry out USAID projects -- the waiver itself was extremely limited. www.npr.org/sections/goa...

Guy who understands neither The Matrix nor Star Trek II