Nimrat Chatterjee

Nimrat Chatterjee

@nimratchatterjee.bsky.social

Assistant Professor at University of Vermont. Previously at Massachusetts Institute of Technology (MIT) and Baylor College of Medicine. DNA repair & mutagenesis enthusiast, believes in compassion and kindness! Lab website: https://www.chatterjeen-lab.com

557 followers736 following112 posts

Nimrat Chatterjee reposted

The OncoAlert Network 🚨
@oncoalert.bsky.social

📢 Join us at the 44th Annual Chemotherapy Foundation Symposium (CFS®): Innovative Cancer Therapy for Tomorrow** 📅 November 11–13, 2026 📍 New York, NY 🇺🇸 💻 Hybrid Meeting — In Person + Online 🎟️ FREE REGISTRATION with code: ONCOALERT 👉 buff.ly/b5A7hsf

Nimrat Chatterjee reposted

HHMI
@hhmi-science.bsky.social

Every cell has an organelle signature — a “fingerprint” created from the shape, size, & arrangement of its internal structures. Scientists at our Janelia Research Campus can now read these signatures across 1000s of cells, revealing how tissues adapt to diet & disease bit.ly/4j6DmoH 📹 Feliciano Lab@

Nimrat Chatterjee reposted

Jesse Engreitz
@jengreitz.bsky.social

Systematic mapping of enhancers, silencers, and topological elements using prime editing deletion screens www.biorxiv.org/content/10.6... Check out our preprint on next-generation tech for mapping distal regulatory effects! We’re excited to help set this up - please get in touch Thread 👇

biorxiv.orgSystematic mapping of enhancers, silencers, and topological elements with prime editing deletion screensNoncoding regulatory elements in the human genome can control gene expression through distinct mechanisms, including acting as enhancers, silencers, or topological elements. However, we lack tools to ...
Shawn Cai@xshawncai.bsky.social

Have you ever looked at a gene in IGV or a genome browser and wondered “What are all those (ATAC-seq/H3K27ac/CTCF ChIP-seq/…) peaks doing?” 🤔 I’m thrilled to share that we developed a new technology called Swap-seq to answer that exact question. Swap-seq: www.biorxiv.org/content/10.6...

biorxiv.orgSystematic mapping of enhancers, silencers, and topological elements with prime editing deletion screensNoncoding regulatory elements in the human genome can control gene expression through distinct mechanisms, including acting as enhancers, silencers, or topological elements. However, we lack tools to ...
Nimrat Chatterjee
@nimratchatterjee.bsky.social

This is horrible and may not be the only example where a female scientist is stepped on.. History is full of it..

Science Magazine@science.org

Exclusive: A new analysis refutes James Watson’s claim that he was the first to recognize the significance of the famed photograph 51. https://scim.ag/4rTKck8

scim.agHow did Rosalind Franklin miss the helix in her iconic DNA image? She didn’tNew analysis refutes James Watson’s claim he was first to recognize significance of famed photograph 51
Nimrat Chatterjee
@nimratchatterjee.bsky.social

Our work in collaboration with the Hadden Lab on the REV7 inhibitor and mitotic sensitization of colorectal cancer cells is now available on bioRxiv: www.biorxiv.org/content/10.6...

biorxiv.orgTargeting REV7 exposes a mitotic vulnerability in colorectal cancer cellsTherapeutic resistance remains a barrier to durable treatment of colorectal cancer (CRC), highlighting the need to identify vulnerabilities in resistant tumor cells. REV7 (MAD2L2) is a multifunctional...

Nimrat Chatterjee reposted

Jeremy Berg
@jeremymberg.bsky.social

My quote of the day If you want to be a writer, you must do two things above all others: read a lot and write a lot. There's no way around these two things that I'm aware of, no shortcut. Stephen King

Nimrat Chatterjee
@nimratchatterjee.bsky.social

Have you ever had a one-on-one conversation with a scientist working to solve a health problem? Now you can. Meet UVM scientists and physicians. Ask your questions. Come have a conversation with them. Come curious. Discover why research matters. Join us at www.uvmhealth.org/classes-and-...

uvmhealth.org2026 Health Equity Summit | University of Vermont HealthThe 2026 Health Equity Summit is a collaborative space for health and health care professionals, community leaders, researchers, advocates and other change-makers to learn from one another and build p...

Nimrat Chatterjee reposted

Itai Yanai
@itaiyanai.bsky.social

🔥Does academia stifle creativity? This new perspective argues that academia is currently structured to select against creativity, intellectual risk-taking and bold ideas. Young scientists – best positioned for new ideas – are particularly incentivized to play it safe. www.nature.com/articles/s41...

Nimrat Chatterjee reposted

HHMI
@hhmi-science.bsky.social

Antibiotic resistance isn't just a genetic problem; it's ecological. New research from #HHMIInvestigator Harmit Malik & co shows that when a dangerous bacterium shares space w/a common fungus, it can be pushed toward resistance it wouldn't develop alone — but with a built-in weakness bit.ly/4g1jLnZ

Nimrat Chatterjee
@nimratchatterjee.bsky.social

I agree! AI will sap student’s ability at critical thinking and pursuing innovation.

Natasha Singer@natashanyt.bsky.social

Great column today by my nytopinion.com colleague @jessgrose.bsky.social on the campaign to spread A.I. in schools, with little evidence of its benefits -- and a number of emerging studies on its learning risks. www.nytimes.com/2026/08/26/o...

nytimes.comOpinion | American Students Shouldn’t Be Guinea Pigs for ChatbotsEvery minute of delay in regulating A.I. use in schools is another opportunity for Big Tech to fill the vacuum.
Nimrat Chatterjee
@nimratchatterjee.bsky.social

Excited to share our recent publication in collaboration with the Hadden lab, where we characterized potent REV7 inhibitors. One of them holds great promise! Kudos to Vihit and Colin for getting the many assays completed !! chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/...

chemistry-europe.onlinelibrary.wiley.comDocking‐Based Virtual Screening Identifies a Small‐Molecule Inhibitor of the Translesion Synthesis REV7/REV3 Protein–Protein InteractionComputational screening identified a small-molecule scaffold that inhibits REV7 protein–protein interactions. Initial structure–activity relationships were performed and compounds capable of synergiz...

Nimrat Chatterjee reposted

Admirable Women
@admirablewomen.bsky.social

Biochemist Gerty Cori won the 1947 Nobel Prize in Physiology/Medicine (shared) becoming the: + First American woman & 3rd woman overall to win a Nobel in a science category + First woman to win in Physiology/Medicine She was born #OTD in 1896. She won the Nobel Prize for...(1/2) 🧵 #WomenInSTEM

Nimrat Chatterjee
@nimratchatterjee.bsky.social

Over the past couple of days, I have heard a lot of discussion about AI and scientific writing. Out of curiosity, I pasted the introduction of my 2016 DNA repair article into an online AI checker, and it flagged it as 60- 80% AI-generated text! What?AI didn't exist then!

Nimrat Chatterjee
@nimratchatterjee.bsky.social

Excited to share that our latest work has now been published in PNAS! This project has been years in the making, and I'm incredibly grateful to all of my collaborators and trainees who helped bring it to completion. www.pnas.org/doi/10.1073/...

pnas.orgDENV-4 infection suppresses transcription of DNA repair genes | PNASThe molecular mechanisms behind Dengue virus-dependent host pathogenesis, especially genome instability, remain largely unclear. This RNA virus cau...
Nimrat Chatterjee
@nimratchatterjee.bsky.social

Forever chemicals are bad for health. There is no version (food, wrapping material, clothes, everyday use products) that is safe. Kudos to these significant steps in Europe!!

Oliver@oliver48.bsky.social

"‘Major victory’: Sweden plans to ban forever chemicals in everyday products ahead of EU" www.euronews.com/2026/07/24/m...

euronews.comSweden to ban cancer-causing ‘forever chemicals’ sooner than EUSweden plans to ban forever chemicals in kitchen appliances and clothing by 2028. When will the EU follow suit?

Nimrat Chatterjee reposted

Admirable Women
@admirablewomen.bsky.social

Chemist & X-ray crystallographer Rosalind Franklin's meticulous research was instrumental in uncovering DNA's molecular structure. Most famous for her role in the DNA double helix discovery, her work also revolutionized our understanding of viruses & coal. She was born #OTD in 1920. #WomenInSTEM 🧵

Nimrat Chatterjee
@nimratchatterjee.bsky.social

Join us for an excellent installment of discussions with leading editors in the DNA repair and mutagenesis space!

Environmental Mutagenesis and Genomics Society@emgsus.bsky.social

NEXT WEEK: Join us for a new #EMGS webinar: "Gate Keepers and Gate Crashers: The Collaborative Roles in Scientific Publishing" presented by the MMA SIG, featuring Drs. Robert W. Sobol, David Josephy, Catherine Klein and Bennett Van Houten! Read More and Register Now! emgs-us.org/event/25GKGC

Nimrat Chatterjee
@nimratchatterjee.bsky.social

This is the essence of a Ph.D., try, try again, and try even more, and never give up!

Richard Sever@richardsever.bsky.social

"Despite years of failure...doubts about what I was doing with my life...years of lackluster results...my PhD research is not a complete waste" Max's story of how we got checkpoint inhibitors should inspire any PhD worried their work's going nowhere theimmunebeyond.substack.com/p/a-brief-hi...

theimmunebeyond.substack.comA Brief History of Checkpoint BlockadeA major medical breakthrough, interrupted
Nimrat Chatterjee
@nimratchatterjee.bsky.social

Super cool work from the McVey Lab!

McVey lab@mcveylab.bsky.social

We teamed with Jim Crott's lab at BU to show that administration of freeze-dried Parabacteroides distasonis extends Drosophila mean lifespan by preventing leaky guts. How? Maybe hormesis. A fun collaboration that features the work of 8 Tufts undergraduates! www.aginganddisease.org/EN/10.14336/...

aginganddisease.orgLifelong Consumption of Freeze-Dried <i>Parabacteroides Distasonis</i> Improves Gut Barrier Integrity and Extends Lifespan and Health Span in Drosophila Melanogaster.<p>Chronic inflammation has been shown to be associated with aging. In <i>Drosophila melanogaster</i>, age-related inflammation in the gut results in a disruption of gut barrier integrity, which can l...

Nimrat Chatterjee reposted

Matt Yousefzadeh
@mattyousefzadeh.bsky.social

grants.nih.gov/grants/guide...

grants.nih.govNOT-OD-26-086: Request for Information: Proposal to Cap the Number of Simultaneous Research Project Grants per Principal Investigator to Support More Researchers and Maximize Scientific Productivity a...NIH Funding Opportunities and Notices in the NIH Guide for Grants and Contracts: Request for Information: Proposal to Cap the Number of Simultaneous Research Project Grants per Principal Investigator ...

Nimrat Chatterjee reposted

Daniel Lipka
@dblipka.bsky.social

🧵 NEW PAPER in @bloodjournal.bsky.social! Why do IDH1 mutations almost exclusively drive myeloid #leukemia, while IDH2 mutations occur in both myeloid AND lymphoid cancers? 🤔 #AML #Epigenetics Despite sharing the same biochemical mechanism, they are NOT equivalent. Here's what we found 👇

Nimrat Chatterjee
@nimratchatterjee.bsky.social

It's the best feeling in the world when your graduate student defends their Ph.D. successfully! Dr. Victor began his Ph.D. training at the start of COVID and persevered through all crises and obstacles. He is looking for an industrial position, if anyone is hiring.

Nimrat Chatterjee reposted

Admirable Women
@admirablewomen.bsky.social

Biochemist Elizabeth Bugie co-discovered streptomycin (with Selman Waksman), the first antibiotic against Mycobacterium tuberculosis. Waksman went on to win the 1952 Nobel Prize for Medicine & took full credit for the discovery. Bugie died #OTD in 2001. #WomenInSTEM #MatildaEffect (1/2)

Nimrat Chatterjee reposted

Jason Shepherd
@jasonsynaptic.bsky.social

It’s brutal in academia right now. A lot is out of our control, but it doesn’t cost anything to remember that there are humans behind papers and grants…reviewers, program officials and funders can be more empathetic in the face of unprecedented chaos in the US scientific enterprise.