Peter Schafran

Peter Schafran

@peterwschafran.com

Research Scientist at Duke University. I work on hornwort and quillwort genomics and systematics

34 followers52 following22 posts

🧬 GENOMES IN THE WILD! 🌿💻🚀 This week, rising high school juniors and seniors stepped into the world of genomics at Catawba College at the Bill and Shari Graham Genomics Laboratory.

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Campers collected environmental DNA, applied next-gen sequencing, and used bioinformatics to assemble whole genomes and interpret environmental DNA. But the experience does not stop at the laboratory door: students are also learning how scientific discoveries can become viable products.

Genomics. Bioinformatics. Environmental sustainability and discovery. Entrepreneurship. That is what happens when science and business come together—and it is an extraordinary opportunity for the next generation of innovators!

🧬 GENOMES IN THE WILD! 🌿💻🚀 This week, rising high school juniors and seniors stepped into the world of genomics at Catawba College at the Bill and Shari Graham Genomics Laboratory.

Led by an outstanding team of scientists and entrepreneurs—Dr. Peter Schafran (Duke University); Pabel Delgado, (Asterism Healthcare) and Dr. Francisco Camacho (Graham Genomics Laboratory) —students explored the entire journey from environmental discovery to real-world innovation.

... John Evans at Atlanta Botanical Garden’s Southeastern Center for Conservation started ex situ collections last year that allowed us to get all the material we need to keep our conservation genomics project on time. Much more comfortable than being out on a blazing rock sampling too!

It isn’t just rare plants that rely on granite outcrop pools, they’re also home to aquatic invertebrates like shrimp, copepods, rotifers, and ostriches. Amphibians cross the vast expanses of bare rock to lay eggs there too.

For three hundred million years — since quillwort ancestors dominated Earth’s earliest forests — rainfall has eroded away these rocks with ephemeral rivulets and pools.

Species like black-spored quillwort in particular need high-rimmed pools that hold in water and prevent the thin soil from being washed away. In the US their adaptation to this habitat is a new phenomenon, evolving within the last five million years.

These little oases are entirely dependent on rainfall. The quillworts that live here have adapted by shortening their life cycle and shifting their growing season to winter and spring. Their spores mature in early summer as the pools dry out and plants enter dormancy.

Not many outcrops are well protected. They attract activities like trash dumping, off-roading, quarrying, and bonfires. As a result, about 50% of black-spored quillwort populations have been extirpated in the last 100 years.

An unusual Isoetes, black-spored quillwort grows over bare rock in a thin layer of sand where rainfall collects during the winter. It will survive the summer in the soil as spores and desiccation-tolerant rootstocks. Quillworts have adapted to this habitat several times around the world.

Peter Schafran reposted

A couple years ago @tarobison.bsky.social asked me what I thought of this isoform in my gene models and I said it was probably just a bad prediction. Never underestimate the weirdness in your data!

Fay-Wei Li@fernway.bsky.social

Our work on #hornwort #pyrenoids is finally out in @science.org! 🎉 We uncovered how hornworts pack their Rubisco into pyrenoids and successfully recreated them in Arabidopsis. A key step toward engineering more efficient photosynthesis in crops @btiscience.bsky.social www.science.org/doi/10.1126/...

Peter Schafran reposted

Peter Schafran reposted

It's the funding of taxonomic research & training that's dying out. Without an ability to identify life forms, we can't recognize/quantify invasions & extinctions and their impacts on ecosystems. Imagine trying to repair a complex steel structure if you can't distinguish different types of bearings.

Peter Schafran reposted

It’s hard to believe our summer undergraduate researchers are wrapping up in just a few weeks! This summer of science has flown by. Catch up on their adventures in the lab, out in the field, around Ithaca, and beyond!

This seems to work really well! Improved a draft genome with N50=0.5 Mb (flye 2.9.4/hifiasm-0.19.8), increased to N50=5 Mb (11 Mb after removing all the repetitive element contigs)

Peter Schafran reposted

Replying to @maddyseale.bsky.social

(2/2) Giant sex chromosomes were discovered in Silene latifolia more than 100 years ago. Two papers back to back now show the sequence of the 550 Mbp Silene Y chromosome helping to understand sex determination www.science.org/doi/10.1126/... www.science.org/doi/10.1126/... #plantscience

science.orgRapid and dynamic evolution of a giant Y chromosome in Silene latifoliaSome plants have massive sex-linked regions. To test hypotheses about their evolution, we sequenced the genome of Silene latifolia, in which giant heteromorphic sex chromosomes were first discovered i...

Peter Schafran reposted

I am very proud of UMN Duluth undergrad Isabel Smalley, whose summer REU project led to co-authorship on her first paper, now out in Nature Plants! 🎉

Peter Schafran reposted

Peter Schafran reposted

Peter Schafran reposted

Peter Schafran reposted

One thing yinz should all know is whenever you write a title of the form <Catchy Phrase> [colon] <Description Of What The Paper is About> I reserve the right to decide whether or not the phrase following the colon is interesting or informative enough to be worth the aesthetic cost to my bibliography

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