Piyush G.

Google introduced AlphaGenome: A new AI tool that predicts genetic variant impacts on gene regulation and disease biology, accelerating scientific discoveries! 🧬🔬 #AI #Genetics #Science #Technology Read more: deepmind.google/discover/blo...

Breakthrough from Google DeepMind: AlphaGenome is Here 🧬

Interesting... but we need better data for this to work www.nature.com/articles/d41... #genomics #artificialintelligence #dna #bioinformatics

always always always run the sample data first when testing a new program #bioinformatics

It's great to see Windows Subsystem for Linux being open source by Microsoft! 🎉 I've been using WSL2 for my everyday Linux CLI tasks for Bioinformatics 🖥 🧬 – personally and professionally. #WSL #OpenSource #Microsoft #Linux #Development #Technology Blog Post: blogs.windows.com/windowsdevel...

Regeneron brought 23&Me customer data for $256M! 💰 This is HUGE for RWE data utilization, but will security & data privacy remain the same? 🤔 🧬 🖥 #Biotech #DataPrivacy #Investment #Healthcare #Technology Full press release: investor.regeneron.com/news-release...

🧪 The Arc Institute's Evo2 models DNA like an LLM models language, predicting mutations, gene function, and evolutionary signals. With 40B parameters trained on 128K genomes, it hints at AI-driven biological discovery. 🧬💻 #MLSky Link to the paper: https://arcinstitute.org/manuscripts/Evo2

Accurate. #chemsky By instagram.com/nathanwpyles...

This is what I have added to my .bashrc file alias untar="tar xvf" alias untgz="tar xvzf" alias untargz="tar xvzf" alias unbz2="tar xvjf" #Linux #Bash #bioinformatics

Benchmarking AI Models for In Silico Gene Perturbation of Cells https://www.biorxiv.org/content/10.1101/2024.12.20.629581v1 🧬🖥️🧪

🎁 New RNA-Seq tutorial! Learn to run differential expression analysis with DESeq2, and create your own bioinformatics projects using public data and the Expression Atlas 🧬 🖥️ youtu.be/NGbZmlGLG5w

Put 👏🏼 the 👏🏼 sample 👏🏼 size 👏🏼 in 👏🏼 the 👏🏼 abstract 👏🏼

Friends don't let friends make bad graphs repo has been updated! Friends don't let friends use histogram for small sample sizes. Bin numbers affect the appearance of histograms, thus not robust to small (and modest sample sizes). They stabilize w/ large sample sizes. github.com/cxli233/Frie...

Ok so this #deepvariant caller update from #google is BIG. github.com/google/deepv... - 1.6x time reduction (40% increase ??) - Pangenome integration - New model and improvements over previously model Excited to try this new update 🧬💻 #bioinformatics #wgs #ngs #variantcalling

New in @theinnovation.bsky.social! Thirteen years of clusterProfiler. This article provides a comprehensive review of the 13-year developmental trajectory of the research team in advancing #clusterProfiler. Read more doi.org/10.1016/j.xi... #bioinformatics #genomics #lifesciences

When you check on your cell culture after the weekend

Has #Bioinformatics usage in #genomics increased Patient's survival rate in #cancer ? AT SCALE Personalised Medicine is still #trending but I believe we will need more mass adoption with optimised cost to see it go mainstream. 🧬🖥

This is a sad state of Cancer treatment in India, where we already are struggling with the cures. Main stream public speakers are peddling pseudo-science. Irony is the patient herself is Dr. & went through rounds of modern treatment & chemotherapy.

What if we can store that Megabytes of data (0101) in those Megabases (ATGC) ? And then use this to train ourselves like a RAG for LLM technique to get better at things 🤔💭

www.nature.com/articles/d41...

TIL, logo for HOMER tool 🧬💻 is literally Homer Simpson🍩

Hello grch38/hg19 users, have a good day ! 🧬🖥

We strongly suggest that academic publishers and other platforms that host research rapidly implement a Share to Bluesky button for their articles. Here's how: docs.bsky.app/docs/advance... #AcademicSky #HigherEd #Altmetrics

New GPU-based MMseqs2: 20x faster searches on a single L40S (approx. as fast as a RTX 4090) vs. a 128-core CPU. This work enables to set up a very cost-efficient ColabFold MSA GPU server. 🧵🧵 📄 www.biorxiv.org/content/10.1... 💾 mmseqs.com 🗞️ developer.nvidia.com/blog/boost-a...

A thread with some new starter packs in genomics and bioinformatics 🧵 1/13...

It would be more lively if National Human Genome Research Institute (NHGRI) is on @bsky.app They post the most funny (& definitely informative) memes on LinkedIn. Nobody is able to match their vibes (yet!)

We already settled this; @mikelove.bsky.social united us under the banner of Computeral Bioinfology!

--dryrun option on #aws is so underrated. I was about to delete my whole genome reference instead of just RSEM Index, if not for dryrun it would have been deleted by now. +10 for whosoever came up with this idea, thanks kind stranger

Can we appreciate Google's Deepmind AlphaFold 3 going open source ? Few (including myself 😛) criticised this with the initial Nature publication Here's the link: github.com/google-deepm... #alphafold3 #opensource #google #proteins