Steve Fletcher

If Elizabeth Holmes had peaked today, perhaps she could have escaped prosecution altogether, Idrees Kahloon argues: “Amid all the chicanery of the second Trump administration, another Holmes-level deception wouldn’t register as anything remarkable.”

If I could give one piece of scientific advice, it would be to avoid doing what everyone else is doing. Unless you want funding and people to care about your work.

Henri Kagan is still alive too! Maybe with Donna Blackmond?

Asymmetric autocatalysis - kenso soai

2/3

I guess technically it was my vote for last year

wow - that was my guess (but I thought they would include Blackmond @donnablack.bsky.social )

Just in case you were wondering..this is what a true Hero looks like...

Researchers Identify Gene Responsible For Visualizing Murder After Touching Missing Person’s Sweater https://theonion.com/researchers-identify-gene-responsible-for-visualizing-murder-after-touching-missing-persons-sweater/

The government has until about 2030 to work out a sustainable way to fund higher education

I've finally found it. The most painful science montage in movie history. Mega Shark Versus Giant Octopus (2009) Yes, Gen X, that is singer Debbie Gibson as oceanographer 'Emma MacNeil'. But the important thing is: she's keeping an accurate lab notebook.

Is YOUR Child Secretly Texting About the Second Run of Columbo Episodes (89-03)? Look For These Acronyms: LOL: Looking Old, Lieutenant OMG: Oh…McGoohan’s Geriatric FFS: Featuring Fisher Stevens NSA: No!! Shatner Again?!

Another Oxford cargo bike theft!! Mine is customised by having a lot of stickers and nail varnish my kids did on it. Stolen on Meadow Lane at 18.30 today locked to a Sheffield stand. Please LMK if anyone sees it for sale. Probably in Cambridge. ;)

I wish Calgary would embrace other themed costume weeks like it does Stampede. There should be a week where we dress up like magicians. Another where everyone is now a zebra. It would be good.

I'm not sure I've ever seen a single sentence go downhill this far and this fast

“Putting a perfect GPA in reach of so many students perversely deters them from taking classes that could threaten it,” Harvard professor Joshua Greene argues. “We should liberate our students from the tyranny of the impeccable transcript”:

For more than a decade, a seventh-grade math teacher used technology in his classroom. This year, he took the Chromebooks away—and quickly learned how the computers were holding his students back, Jenny Anderson writes.

AI detection systems - its AI, why would anyone concerned about AI trust these?

www.organic-chemistry.org/abstracts/li... A Rh-catalyzed asymmetric reductive Heck reaction of aryl, heteroaryl, or vinyl boronic acids and phenyl pyridine-1(2H)-carboxylate provides 3-substituted tetrahydropyridines

We are excited to be recruiting into 3 Associate Professorship's in @oxfordbiochemistry.bsky.social. Come join us as a colleague and benefit from our vibrant and multidisciplinary environment. Reach out to me if you have any questions. Please repost! (tinyurl.com/48deybuu) (tinyurl.com/4pdvjaft).

I can't be the only one who is made /uncomfortable/ by the way that razor clams burrow into sand, right? The final moments of this video by Kate Crump on the Oregon coastline are sort of the crowning glory of horror. 😬 But how does this even work? Let's talk about bivalve mobility (if we must).

Congratulations to the prize-winners from our recent Early Career Researcher Symposium and Poster Event in Organic Chemistry & Chemical Biology, sponsored by Pharmaron. Pictured are poster prize winners Stanley Oppong, Oskar Ford, Sara Borghi, Nandini Guzman and Maddison Lovell.

Banbury gets this, and we get.. more lab space. CITY CENTRE PLAYGROUND WHEN, @oxfordcitycouncil.bsky.social ?! Maybe we should #bemoreBanbury Bit of imagination?!

Without naming your job, tell me something you say over and over again at work. What does the TLC look like?

A colleague asked me if anyone can identify this glassblowing tool. From the collection of a distinguished long gone colleague. Happy to hear thoughts.

organic chemistry IV art history the new German film society and freedom contemporary myths

Activity-based protein profiling covalent small molecules that potentiate the activity of the METTL5:TRMT112 complex through binding to a complexoform-restricted allosteric pocket absent in other TRMT112:methyltransferase complexes www.nature.com/articles/s41...

We're Hiring! If you are interested in a PDRA post with the Mehta group, please apply! @ox.ac.uk @oxfordchemistry.bsky.social my.corehr.com/pls/uoxrecru...

In @science.org for chemsky this week, Michael Willis’ group make beta-lactam analogues with S=O in place of C=O, using energy-transfer reactivity of N-silyl sulfinylamine precursors. www.science.org/doi/10.1126/...

Two (2) corkscrews went down trying to open this

Ok here it is - out of 44 FDA approvals this year, 31 are small molecules (70%), 26 of those are oral drugs (84%), 22 of them are chiral (71%). This is the largest number and percentage of chiral FDA approved molecules in a single year. Fitusiran is not a small molecule, bonus.

Come be my colleague @ucdchemistry.bsky.social! We're currently looking for an organic chemist (broadly defined) to start as a permanent (i.e., tenured) assistant professor. Job reference (www.ucd.ie/workatucd/jo...) is 019237. Due date Feb. 27, 2026 Reach out if you have questions!

Beep was nasty…

On Dec. 6, 1917 at 8:45 a.m., the Imo and Mont-Blanc (which was packed with explosives) collided in Halifax Harbour. At 9:05 a.m., the Mont-Blanc exploded. The 2.9 kiloton blast levelled most of Halifax, killed 1,700 and injured 9,000. This is the story. 📸 LAC 🧵 1/12

watching The wire - Omar easily one of the best bad guys ever

A movie that takes place where I’m from

The chemotypes within FDA approvals so far this year are quite diverse. Most of the 2025 small molecule approvals are chiral with four covalent electrophiles.

any suggestions for a equivalent reagent for Na/Hg?

#ICIQJobs 🚀 Join ICIQ as a Junior Group Leader! We’re seeking talented, innovative scientists ready to push the frontiers of research. Apply now 👉🏼 careers.iciq.org/jobs/6745027... @cerca.cat @bist.eu #SOMM_alliance

It’s England so I appreciate how not everyone ‘gets it’ - but somehow my kid ended up with a moul piece of garlic and another got a brussel sprout from the same house. I suggested that they might not understand the full implications of ‘trick or treat‘ …

J. H. Christ...

Pen stealing isn’t a big deal - my Asian food take out uses a pen from my bank But DON’T EVER touch a hood Sharpie - get your own