Now that the cat’s out of the bag: Excited to announce I will be starting a research group as a Sandler Fellow this August at UCSF! We will study the evolution of protein toxins at the host-pathogen interface across scales of biological organization. Learn more here:
www.tarnopollab.org
Stoked for this GRC and also for the corresponding GRS June 12-13, co-chaired by @meganbehrmann.bsky.social and myself. Will be an excellent meeting for students and postdocs in functional evolutionary genetics working in diverse model systems! More to come here:
www.grc.org/molecular-me...
@joethorntonlab.bsky.social and I are thrilled to co-organize the 2027 Molecular Mechanisms in Evolution GRC, June 13–18, in beautiful Portland, Maine!
See our ⭐stellar⭐ lineup of speakers ⬇️ spanning evolutionary biochemistry, cell biology, development, behavior...
www.grc.org/molecular-me...
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Hey #Drosophila folks - the #flycross#mentee survey is open for #grad students, #postdoc and #pretenure faculty. ~95 mentors from across the world, with diverse expertise. The co-chairs @shyama13.bsky.social and @jocmcdonald.bsky.social have done a phenomenal work in taking the program forward 🎉
Our latest work now on bioRxiv! We found evidence for multiple independent HGTs of the anti-parasitoid effector cdtB in drosophilids, including anciently in the last common ancestor of subgenus Drosophila 👀 You can browse our data here: trnpl.github.io/antiparasito...
Horizontal gene transfer rivals gene duplication as a source of anti-parasitoid immune innovation in the Drosophilidae https://www.biorxiv.org/content/10.64898/2026.09.15.751804v1
This work could not have been completed without the help of wundergrad Ryan Wang, who led all the work on PPO annotation curation and analysis, and the inimitable @bernardkim.bsky.social, who built the most comprehensive Drosophilidae species phylogeny to date for this study (406 species)!
Fly people: please consider nominating your PhD student who completed their dissertation in any area of Drosophila research between July 2025 and December 2026 for the @genetics-gsa.bsky.social Larry Sandler Award. Nominations due by November 12: genetics-gsa.org/awards/larry...
Nominations for the GSA Larry Sandler Award are now open! genetics-gsa.org/awards/larry...
This award recognizes an outstanding PhD thesis (graduating between 07/2025 and 12/2026) in any area of Drosophila research.
Include 1) the thesis abstract, 2) the Nominee's CV and 3) a nomination letter.
I’m thrilled to share that our search for a tenure-track colleague in my *truly wonderful and collegial* Genetics, Genomics, Evolution and Development Division in the MCB Department at Berkeley @berkeleymcb.bsky.social is live! Please share this broad search widely: aprecruit.berkeley.edu/JPF05481
Avocados come in 2 varieties - A-types start each day female and switch to male midday. B-types do the reverse. In work just published from the last chapter of my PhD, we show this system evolved 40+million yrs ago and is regulated by alleles of 1 transcription factor
www.pnas.org/doi/10.1073/...
Now accepting applications for our 2027 Simons Graduate Fellowships in Ecology and Evolution! These awards support students entering U.S.-based Ph.D. programs to conduct #ecology and #evolution research. Deadline is June 30, 2026: bit.ly/4umYKZd#science
Are you curious about animal origins? Want to perturb their genetics to find out more? Now it's a lot cheaper: the FUNR @frutag33.bsky.social Lab's effort to make transfection more accessible for choanos (& relatives) is up now! 🧬
A brief 🧵1/5
Proposals are due May 18 for this year’s Graduate Research Excellence Grants! Up to $2500 for 1st and 2nd year grad students and up to $3500 for 3rd years and above. Learn more and apply now! www.evolutionsociety.org/content/soci...
Now that the cat’s out of the bag: Excited to announce I will be starting a research group as a Sandler Fellow this August at UCSF! We will study the evolution of protein toxins at the host-pathogen interface across scales of biological organization. Learn more here:
www.tarnopollab.org
Very much looking forward to working on two of my favorite things (flies and toxins) in this next stage of my career. Happy to talk to interested folks either virtually or here at #Dros26!
Very honored to receive this award from GSA! I have immense gratitude for my advisor @nkwhiteman.bsky.social, labmates, collaborators, mentees, and the fly community, who in many ways potentiated my graduate research.
Looking forward to sharing my work at my favorite meeting in my favorite city!
We’re excited to announce @tarnopol.bsky.social as the recipient of the 2026 Larry Sandler Award! 🎉 She’ll present the Larry Sandler Memorial Lecture during the #Dros26 opening session on March 4—she'll share how her research explores how protein toxins evolve to shape host–parasite interactions.
Are you a Drosophila researcher & member of @genetics-gsa.bsky.social (at any level of training)?
Please vote in the Flyboard elections (we have an amazing slate of candidates) before Feb 20, 2026. Please check your email or go to this website to vote: genetics-gsa.org/2026-fly-boa...
Pl repost.
Did you know there are 2 types of avocado varieties? A-types switch from female to male, B-types male to female, within a single day. This reciprocal sex alternation promotes cross-pollination and has a simple genetic basis. Read more in this recent preprint from the final chapter of my PhD thesis 🥑
Excited to share the latest work by outstanding PhD student @kdc509.bsky.social. This was one of our first forays into experimental evolution and uncovered some cool connections between potassium transport and antimicrobial resistance in S. aureus. Major kudos to Killian!
FlyBase needs your help! We ask that European labs continue to contribute to Cambridge, UK FlyBase, whereas US and other non-European labs can contribute to US FlyBase. For more information and how to donate: wiki.flybase.org/wiki/FlyBase...
@ucberkeleyofficial.bsky.social undergrads, there is still space in this course on the cellular, genetic, and developmental basis of evolution taught by Professor Nicole King and me this Fall. Find out why, as Dobzhansky, said "nothing in biology makes sense except in the light of evolution."
Applications now open for the SSE GREG Rosemary Grant Advanced Awards! These grants provide up to $3500 to expand your dissertation work. Submit your proposal by September 15!
www.evolutionsociety.org/content/soci...
📢 There is a lab technician or lab specialist position available in my lab, starting fall 2025. The position will involve molecular biology, microbiology, drosophila work, and more. Please share with anyone who may be interested and apply here: jobs.virginia.edu/us/en/job/R0...
Pleased this paper led by Teru Matsunaga at University of Tokyo (former postdoc) and in collaboration with many colleagues is out @official-smbe.bsky.social Molecular Biology & Evolution: doi.org/10.1093/molb.... Palp-expressed Or42a is an isothiocyanate sensor and can drive aversion to ITCs…
We currently have a call for support that has gone out to European labs, to support FlyBase-UK. We are asking our colleagues from labs in the US and other countries to wait for a similar call to them that will go out in the near future, to support the US sites. We thank you for your patience.
URGENT: FlyBase has lost practically all its funding overnight; even user fees are tied up in denied grant funding. 🤬🤯
Any lab using @flybase.bsky.social please donate using the link in post below.
This incredible community, on whose backs our #Drosophila labs depend, can't be left out to dry.
Get the word out far and wide. New opportunity from the Simons Foundation in the Eco-Evo space.
2026 Simons Graduate Fellowship in Ecology and Evolution Awards, due July 31, 2025, only for incoming PhD students who plan to start their PhDs in Fall 2026.
www.simonsfoundation.org/grant/simons...
🚨New paper alert!🚨
We show that hummingbird beaks have changed in shape & size since around WWII, driven by the rise of commercialized feeders! 🧵
📄 Paper: dx.doi.org/10.1111/gcb....#ornithology#evolution#GlobalChangeBiology
I know you like #Drosophila and I know you like #Genomes - but do you also like #Genes? Coding DNA annotation of 304 species of Drosophilidae! www.biorxiv.org/content/10.1...
Genomics and reproductive biology of Leptopilina malgretoutensis Buffington, Lue, Davis & Tracey sp. nov. (Hymenoptera: Figitidae): An asexual parasitoid of Caribbean Drosophila https://www.biorxiv.org/content/10.1101/2025.03.28.645512v1
Excited to be in sunny San Diego for my 5th (!) fly meeting #Dros25! I will be giving a poster (329T) tomorrow on some new host-parasitoid experiments — would love to chat with interested folks!
#Drosophila community: Dr. Istvan Ando has generously donated his invaluable anti-hemocyte monoclonal Abs to the #NIH-founded public repository @dshb-antibodies.bsky.social in #Iowa. We’ve tested several of them and they look great. See the🧵 for details.
(1/5)
Excited to share the major work of my dissertation, out now in @currentbiology.bsky.social! We use Drosophila genetics to dissect the evolution of phage-derived toxins that were horizontally transferred to insects and now function as potent anti-parasitoid defenses (1/n): tinyurl.com/2k9ypyxr
Our study highlights how HGT can potentiate rapid evolution of adaptive traits in animals, given the right regulatory context. Lots more interesting biology described in the manuscript, and lots of new questions to follow up on next! (7/n)
Feeling very lucky that my out-there idea from the beginning of grad school worked out, and that I got to work with excellent collaborators here and abroad who made it all possible. Two wonderful undergraduate co-authors, Jossie Tamsil and Jaden (Ji Heon) Ha, were instrumental in this work. (8/fin)
Excited to share the major work of my dissertation, out now in @currentbiology.bsky.social! We use Drosophila genetics to dissect the evolution of phage-derived toxins that were horizontally transferred to insects and now function as potent anti-parasitoid defenses (1/n): tinyurl.com/2k9ypyxr
We found that the FusionB toxin was secreted from the fat body to the host hemolymph, where it targetec the serosal tissue of parasitoids and led to increased wasp mortality by 72 hpi. To our knowledge, it is the first toxic humoral anti-parasitoid factor described in Drosophila. (5/n)
The tools in D. melanogaster let us dissect the role of gene regulation in mediating HGT in animals, an area not well-studied. When we expressed fusionB constitutively, instead of in the immune tissues where it is natively expressed in D. ananassae, we observed lethality at early pupal stages. (6/n)
Excited to share the major work of my dissertation, out now in @currentbiology.bsky.social! We use Drosophila genetics to dissect the evolution of phage-derived toxins that were horizontally transferred to insects and now function as potent anti-parasitoid defenses (1/n): tinyurl.com/2k9ypyxr
When I met @nkwhiteman.bsky.social for the first time in Feb. 2020 to set up a rotation in his lab, I pitched moving the genes from D. ananassae into D. melanogaster to see if they confer parasitoid resistance in this naive context. It was a pie in the sky experiment I did not expect to work. (3/n)
Shockingly, one of these genes, a cdtB::aip56 fusion gene we called "fusionB," drove a robust parasitoid resistance phenotype in against two different parasitoid species when expressed in D. melanogaster immune tissues! (4/n)
Excited to share the major work of my dissertation, out now in @currentbiology.bsky.social! We use Drosophila genetics to dissect the evolution of phage-derived toxins that were horizontally transferred to insects and now function as potent anti-parasitoid defenses (1/n): tinyurl.com/2k9ypyxr
The two toxins—cytolethal distending toxin B (cdtB) and apoptosis inducing protein of 56kDa (aip56)—are implicated in a defensive endosymbiosis in aphids. Our lab found HGT of these genes to insects in multiple orders, where they function in anti-parasitoid defense (2/n): tinyurl.com/m9mufn9a