Vardilab

Vardilab

@vardilab.bsky.social

The official account of the Vardi Lab | Microbial Interactions in the Ocean | #phytoplankton #hostvirus #infochemical #stressresponse | @WeizmannScience

228 followers344 following19 posts

Vardilab
@vardilab.bsky.social

Want to explore how protists and giant viruses interact in nature? 🦠 We're recruiting a postdoc to build on this work! 📣 🔬 Fully funded 4-year fellowship: 2 years at Max Planck (Bremen) + 2 at Weizmann (Israel) 📅 Apply by Dec 1, 2026 Interested? ->

Vardilab@vardilab.bsky.social

A new preprint by @amirfromm.bsky.social 📣 How do protists fight viruses in nature? Using single-cell sequencing in an isolated alpine lake, we uncover natural giant-virus infections and reveal the induction of viperin, an ancient antiviral defense, in wild protists 🏔️🦠->

biorxiv.orgSingle-cell-resolved natural giant virus infections reveal conserved protist immunitySingle-cell eukaryotes (protists) are key players in microbial ecosystems. Yet, our understanding of how they interact with viruses in nature and how antiviral defenses shape these relationships remai...
Vardilab
@vardilab.bsky.social

A new preprint by @amirfromm.bsky.social 📣 How do protists fight viruses in nature? Using single-cell sequencing in an isolated alpine lake, we uncover natural giant-virus infections and reveal the induction of viperin, an ancient antiviral defense, in wild protists 🏔️🦠->

biorxiv.orgSingle-cell-resolved natural giant virus infections reveal conserved protist immunitySingle-cell eukaryotes (protists) are key players in microbial ecosystems. Yet, our understanding of how they interact with viruses in nature and how antiviral defenses shape these relationships remai...

Vardilab reposted

EMBO
@embo.org

Don't miss out! One week left to sign up for the EMBO Workshop "Marine microbial chemical communication" in Den Hoorn (Texel), Netherlands, 15–18 March 2027. Deadline: 20 October 2026 https://meetings.embo.org/event/27-marine-communication #EMBOMarineComms #MarineBiology #EMBOevents 🧪

meetings.embo.orgMarine microbial chemical communicationThis EMBO Workshop on Marine Microbial Chemical Communication will bring together researchers at the forefront of understanding the chemical crosstalk of microbial interactions in the ocean. As micr…
Vardilab
@vardilab.bsky.social

📣 A new preprint by noashima.bsky.social! 📣 How does ocean warming affect viral infection? Infection of algae by a giant virus is arrested intracellularly under elevated temperature, with the late replication stage blocked. Infection can later resume, revealing a reversible arrest state 🌊

biorxiv.orgReversible inhibition of viral life cycle in response to elevated temperature in a bloom-forming algaOcean warming is expected to reshape microbial interactions and community composition, with profound consequences for marine biogeochemical cycles. Host virus dynamics are central to these processes, ...
Vardilab
@vardilab.bsky.social

🌊Paper announcement! 📣 Viral infections rewire the metabolic makeup of their host and thereby create distinct chemical signatures. Can we use metabolic biomarkers to diagnose infections of algal blooms in the ocean? Well, take a look at our new article led by Conny Kuhlisch in @pnas.org >>

doi.orgMapping of the viral shunt across widespread coccolithophore blooms using metabolic biomarkers | PNASThe viral shunt is a fundamental ecosystem process which diverts the flux of organic carbon fixed through photosynthesis during algal bloom events ...
Vardilab
@vardilab.bsky.social

The core-resistance genes could serve as potential markers to detect resistant cells during algal blooms. A better understanding of algal resistance mechanisms is key to unraveling the host-virus arms race in the ocean and bloom dynamics. 🌊 >> (2/3)

Vardilab
@vardilab.bsky.social

Advancements in single-cell technologies are opening new frontiers in marine microbiology, helping us answer some of the most fundamental questions in marine microbiology and providing a holistic view of microbial life in the ocean.

Vardilab reposted

Ákos T Kovács
@evolvedbiofilm.bsky.social

A single-cell perspective on host–virus dynamics in the ocean @cp-trendsmicrobiol.bsky.social Opinion from @vardilab.bsky.social www.cell.com/trends/micro...

cell.comA single-cell perspective on host–virus dynamics in the oceanViral infections of marine microbes greatly impact ecological and biogeochemical processes. Typically, these host–virus interactions are studied at the population level using bulk transcriptomics, whi...
Vardilab
@vardilab.bsky.social

📣A new preprint by Talia Shaler! 📣 How do populations develop resistance to viral infections? We mapped the transcriptomic landscape of algal resistance to lytic viral infection and identified a unique set of resistance-related genes expressed in those cells >> doi.org/10.1101/2025...

doi.orgMapping the transcriptional landscape of algal resistance to viral infection reveals a core expression program### Competing Interest Statement The authors have declared no competing interest. Simons FoundationSimons Foundation, https://ror.org/01cmst727, 150809
Vardilab
@vardilab.bsky.social

>> The expression of these resistance-related genes was found to be shared among various resistant strains and included genes with domains linked to innate immune responses that are conserved across bacteria, plants and mammals. 🦠🌊

Vardilab
@vardilab.bsky.social

Using cell-to-cell heterogeneity in response to oxidative stress, we discovered genes linked to either cell death or stress resilience in diatoms. Among the hits we detected was Cathepsin X, a cysteine protease conserved from humans to algae and widely expressed in the oceans. 2/3 >>

Vardilab
@vardilab.bsky.social

Cathepsin X mutants in distant algae had increased resilience to oxidative stress. Our findings shed light on the origin of programmed cell death in unicellular organisms and their strategies to cope with environmental fluctuations. 3/3

You are up to date.