BejaLabTechnion reposted
Protein fibers, a hallmark of Alzheimer’s, spotted making deliveries to sperm | EurekAlert! www.eurekalert.org/news-release...
BejaLabTechnion
@bejalab.bsky.social
the unculturables: exploratory research & beyond. EMBO-YIP 2003, EAM 2012, adERC 2013, EMBO 2024. https://beja.net.technion.ac.il/
1K followers464 following1.2K posts
BejaLabTechnion reposted
Protein fibers, a hallmark of Alzheimer’s, spotted making deliveries to sperm | EurekAlert! www.eurekalert.org/news-release...
BejaLabTechnion reposted
Not all nuclei are the same. We went to some of biology’s most exceptional nuclei 👉 dinoflagellates with genomes 80× ours 👉 Giardia’s twin nuclei 👉 ciliates carrying two nuclei in one cytoplasm & asked a simple question: what sets nuclear density? 🧵 Preprint: www.biorxiv.org/content/10.6...
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🕷️💤 New paper in time for 🎃! Do #spiders really sleep? In our new study on #Portia fimbriata we tested all behavioural criteria of #sleep and found evidence for regulated, two-stage sleep with recurring REM-like stages. Out in @pnas.org! @roesslerdaniela.bsky.social 📄 tinyurl.com/3fky8ze7 🧵1/9
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Fantastic #protistsonsky
Not all nuclei are the same. We went to some of biology’s most exceptional nuclei 👉 dinoflagellates with genomes 80× ours 👉 Giardia’s twin nuclei 👉 ciliates carrying two nuclei in one cytoplasm & asked a simple question: what sets nuclear density? 🧵 Preprint: www.biorxiv.org/content/10.6...
BejaLabTechnion reposted
Happy World Phage Day to all who celebrate... ... delighted to share new work led by Jacopo Marchi, Chadiga Khalek & joint w/Remy Chait on stable coexistence of phage with migrating bacteria driven by the forces of infection, lysis, and chemotaxis. A 🧵 at the interface between known & unknown.
First person infected with rare Shamonda virus: what we know www.nature.com/articles/d41...
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Interesting 🤔 Why DNA uses thymine instead of uracil remains unresolved, since thymine is more susceptible to ultraviolet UV? www.pnas.org/doi/10.1073/... Although thymine is more photoreactive, it preferentially channels UV damage into reversible lesions amenable to nonenzymatic self-repair
BejaLabTechnion reposted
🚨 New preprint 🚨 We’ve discovered millions of viruses from sequencing data but we don’t always know who they infect. Our new tool, VHAMSTeR generates broad virus host predictions across the tree of life (prokaryote, plant, animal, fungi and protist hosts) A thread 🧵👇 www.biorxiv.org/content/10.6...
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BejaLabTechnion reposted
so good to learn more about the enigmatic R-bodies now (in a way following up on our old post from 2016) #MicroSky #ProtistsOnSky
Incredibly excited about our latest work on R-bodies, 5+ years in the making! These coiled protein ribbons extend into ~10 µm needles in a pH-dependent manner & we caught them springing open inside amoebae after P. aeruginosa gets eaten. (animation: Jegg Yoon)🧵1/2 www.biorxiv.org/content/10.6...
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Today together with Prof. John McCutcheon lab @arizonastateuni.bsky.social we have visualized by cryoEM what looks like a very funky ribosome from an insect endosymbiont. We believe there are important evolutionary implications. Here the pre-print: www.biorxiv.org/content/10.6...
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Don't miss the EMBO Global Lecture "Fidelity in obligate symbioses" by EMBO Young Investigator Hassan Salem (John Innes Centre) at the Advanced Industrial Science and Technology in Tsukuba, #Japan, 6 November 2026. 🧪 #LifeSciences #research
BejaLabTechnion reposted
Meet the giant Sissivirus (and its #virophage)! With 4 Mbp genome, Sissivirus is the champion of all known viruses (by genome size). Check the preprint to learn how it got so big. The study led by Julien Andreani, Frederik Schulz @fmschu.bsky.social & Bernard La Scola www.biorxiv.org/content/10.6...
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The Stoy Lab at FSU is recruiting MS and PhD students interested in insect symbiosis and mutualistic (co)evolution. Please share with any students who you think might be interested! Prospective students should email me and attach a CV at kstoy@fsu.edu. Lab Website Here: ksstoy.wixsite.com/stoylab
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Discovery of phage defense systems through component modularity networks: Cell Host & Microbe
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1/6 🧵 Six years in the making! Our new preprint is finally out! We used comparative single-cell transcriptomics to investigate how changes in gene expression contribute to the evolution of complex 3D structures, using Drosophila male genitalia as a model. www.biorxiv.org/content/10.6...
Improving optogenetic control over Gi/o-coupled receptor signaling by optimized GIRK channel expression www.science.org/doi/10.1126/...
BejaLabTechnion reposted
A giant virus with a 4-megabase genome and a vastly expanded repeatome. | bioRxiv
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A new structural study of neorhodopsin (NeoR) by Kirill, Matthias, and Igor! 🌟 The structural basis underlying its extremely red-shifted absorption is explored in this work 🔬 www.biorxiv.org/content/10.6...
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It's a truth universally acknowledged that Current Biology rocks! So we thought, why not put a rock on the cover? True, not a super current rock, at 2.5 billion years old, but deeply connected to biology. To find out more, check out our special issue on Life & Earth! www.cell.com/current-biol...
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How did Life shape Earth — feature by Michael Gross from our special issue! www.cell.com/current-biol...
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New and evolving user programs will combine genomics with AI, automated experimentation and complementary capabilities across DOE user facilities — giving researchers integrated approaches hard to assemble in a single lab. More in our new strategic plan: jointgeno.me/stratplanrelease
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Optimal growth temperature is not an adequate proxy of microbial cold adaptation | ISME Communications | Oxford Academic
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This work led by @jennbrophy.bsky.social and her lead student Vivian in collaboration with my lab & lead student Michaela published online this morning at Nature Biotechnology www.nature.com/articles/s41... Helps limit engr'd microbial functions to target plants Exciting science & amazing collab
We engineer both plants and bacteria to establish non-standard amino acids as a new molecular language for programming plant-microbe interactions. This work contributes to the growing toolkit for precision agriculture and we hope it accelerates the path to a sustainable future!
BejaLabTechnion reposted
BejaLabTechnion reposted
High-resolution structure of monomeric photosystem I from Thermosynechococcus vestitus link.springer.com/article/10.1...
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Biofilm formation and dynamics in the marine cyanobacterium Prochlorococcus www.nature.com/articles/s41...
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In today's installment of the "Unknowns" series, I pitched in with colleagues @kchang.bsky.social & William Broad to tackle a teeny question: How Did Life Arise? Gift link: nyti.ms/4B9lbW5
The biogeography of giant viruses and interactions with Eukaryotes across European lakes www.nature.com/articles/s41...
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Out Now! G-protein-coupled receptor sensing of farnesol controls fungal dormancy and is susceptible to bacterial interference #MicroSky
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Nonlinear distributed sensing of light patterns leads to perceptual distortions in plants www.pnas.org/doi/10.1073/...
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After tRNA, rRNA, mRNA, RluA apparently also modifies phage RNA (E. coli) 🦠 A host enzyme pseudouridylates an RNA bacteriophage genome and accelerates virus production www.biorxiv.org/content/10.6...
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Functions and evolution of viral proteins #virology #viruses #proteins #MicroSky @asm.org journals.asm.org/doi/10.1128/...
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Cover image alert 🎨🚨👇🏼 - check out the amazing drawing of Sophia Zimmermann from our group in Nature Microbiology @natmicrobiol.nature.com ! Fun fact: Sophia initially drew it as a present to Dorentina @humollidorentina.bsky.social when we celebrated her recent paper on TnSeq with phages 🥂😊.
We wrote a short “Behind the Paper” post about our HIDEN-SEQ journey together with @aharms485.bsky.social. Check it out: go.nature.com/4yBHsdy Special to share it with the @natmicrobiol.nature.com cover, featuring the amazing art of the great scientist and artist Sophia Zimmermann from our lab!
Virophage-like viruses replicate with a candidate phycodnavirus of C. parva www.biorxiv.org/content/10.6...
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Viruses have parasites too. Our new preprint shows how phages use VIPR to silence parasitic satellites, and how the satellites fight back with its own decoy VIPR RNAs that redirect VIPR to DNA REP elements in the host genome!! www.biorxiv.org/content/10.6...
Defining the essential genome of diverse phages with phage Tn-seq www.nature.com/articles/s41...
Systematic mapping of bacteriophage gene essentiality with HIDEN-SEQ www.nature.com/articles/s41...
Antisense RNA controls the degradation of phycobilisomes in heterocyst-forming cyanobacteria by a transcriptional interference mechanism academic.oup.com/nar/article/...
From hijackers to architects: the role of prophages in bacterial genome evolution journals.asm.org/doi/full/10....
Unprecedented atlas explores mitochondria across the tree of life www.nature.com/articles/d41...
BejaLabTechnion reposted
Meet the Spaceship-like Vessel Made to Drift Over the North Pole | What The Future www.youtube.com/watch?v=nGzz...
A conditional upper-bound design map for rhodopsin-augmented electro-microbial CO2-to-biomass conversion www.biorxiv.org/content/10.6...
BejaLabTechnion reposted
BejaLabTechnion reposted
A new preprint by @amirfromm.bsky.social 📣 How do protists fight viruses in nature? Using single-cell sequencing in an isolated alpine lake, we uncover natural giant-virus infections and reveal the induction of viperin, an ancient antiviral defense, in wild protists 🏔️🦠->
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Meet the person behind the illustrations of the 2026 Nobel Prize laureates. Check out artist @niklaselmehed.bsky.social. Here he is painting the illustrations for our new medicine laureates, Karl Deisseroth, Peter Hegemann and Georg Nagel.