Xantha Karp

Please comment on "Request for Information (RFI) on Proposed Changes to Reporting Outcomes from NIH Peer Review" by Tuesday (October 13th, 2026). rfi.grants.nih.gov?s=6a2b1c22c3... Here is my comment: 1/6

We’re pleased to highlight Biochemistry Ph.D. candidate Robert Kinobe, recipient of a Seymour Fogel Endowment Travel Award, who presented his research on KFERQ-mediated protein degradation in C. elegans at the MAPSS + DevCell Joint Meeting. Congratulations to Robert and his colleagues!

Are you looking for a postdoc exploring the cell biology of development, defining how cells change shape and move? Do you want to develop a research program & teaching skills preparing you for a position at a college or small University? Our new NIH grant will support those goals 1/n Please share

The CCT chaperonin is a context-dependent regulator of RNA-binding protein phase transitions #micropublication #biology #data #caltechlibrary #Celegans #PhenotypeData #NewFinding https://micropublication.org/journals/biology/micropub-biology-002420

Tim Bestor has left us. This obituary captures him well — you always had to be at your intellectual peak with him, while his trainees always spoke highly of their experiences. He made a massive contribution to epigenetics, a giant in our field. www.genetics.cuimc.columbia.edu/news/memoria...

Very excited to put out this new preprint from the lab that represents our 3rd paper now in the lab's move into the field of identifying bioactive molecules in bacteria using C. elegans and studying how they regulate animal physiology. Really excited about this space- www.biorxiv.org/content/10.6...

Call for Volunteers: C. elegans Managing Editors for microPublication Biology micropublication.org/news/0f62741...

🪱 A behavior analysis in #Celegans highlights that the change in reproductive strategies to increase mating following dauer diapause requires sexually dimorphic changes in behavior. Find out more in #G3journal 🔗 buff.ly/Zgi3QXQ

Under pressure, the DOD just released the text of its secret 10-year agreement with the NIH. Here are the biggest revelations from the document 🧵

Structural biology postdoctoral position open in my lab--apply now! For more information about the lab, see www.umassmed.edu/munsonlab/. Interested candidates should apply through the University of Massachusetts Chan Medical School jobs portal (www.ummsjobs.com/job/11668/).

RNA-binding proteins (RBPs) often bind numerous transcripts - but do they act through a network effect? Our new paper in @plosbiology.org shows that the highly conserved LIN28 RBP controls developmental timing in C. elegans larvae through only two targets. doi.org/10.1371/jour... 1/n

How can a tiny worm shape a scientific career? Join 2026 GSA Mentorship Award recipient @irinakitop.bsky.social of @fredhutch.org on August 20 at 1:00 p.m. EDT as she shares how C. elegans has guided discoveries, collaborations, and approaches to mentorship. 🔗https://buff.ly/iUmQCCQ

Excited to share that in mid-August I'll be opening the Castillo–Quan Laboratory (CORA Lab) as a tenure-track Assistant Professor at Ohio University! We study stress responses, homeostasis & healthy aging in C. elegans. Recruiting two PhD students for Aug 2027. Join us @ohiouniversity.bsky.social!

Job opportunity for a #postdoc in the Updike Lab: The Dustin Updike Lab at MDI Bio Lab uses #Celegans to investigate gene function in the germline, with a particular focus on epigenetic mechanisms that maintain germ cell identity. Apply: https://ow.ly/Mg6i50Zl5rN #sciencejobs #STEMjobs #postdocjob

🪱 A new mutant analysis reveals the functions of miRNA-producing small RNA pathway in #Celegans male fertility, sperm production, and gonad morphology. Learn more in #G3journal 🔗 buff.ly/Sc8hDzk

First paper from the Kasimatis Lab is now online! We investigate of the maintenance of mate plugging in C. elegans along with its function www.biorxiv.org/content/10.6...

Hey C. elegans friends! What's your preferred method for cell-specific knockout or knockdown? Would love any paper recommendations too! Thank you!!!

For #Celegans researchers: want to capture better worm images? Our new paper explains how light scatters from the worm body and reveals practical strategies for improving imaging quality. Check out our new paper in iScience @cp-iscience.bsky.social: www.cell.com/iscience/ful...

This is the biggest threat to American science thus far, and that says a lot, I wrote--the template makes it easy to personalize. 🧪

The Central Michigan University contingent had a fantastic time at #wormtopicmeeting2026 in Madison! C. elegans meetings are the best

Best time to start Standing Up for Science was years ago. Second best time is NOW. 📣Leave public comment ☎️Contact Congress 🚨Register for the @standupforscience.net Emergency Science Meeting tomorrow at 4pm et ONE STOP SHOP: fight2win.standupforscience.net

'If a control experiment fails, does that mean that the entire experiment is poorly designed and you must restart from scratch? Often, yes— but not always. I present five examples where failed control experiments triggered entirely new fields of research.' link.springer.com/article/10.1...

🚨The OMB rule will be the end of science as we know it. MARK YOU CALENDAR for the @standupforscience.net EMERGENCY SCIENCE MEETING June 2nd, 4pm et. We will be giving an overview & assigning EVERY SCIENTIST IN AMERICA their marching orders. REGISTER: events.standupforscience.net/stand-up-for...

I heard from several sources yesterday that NIH is planning to release a Request for Information (RFI) that apparently will include this: Scores and percentiles for NIH grant applications will not be shared with applicants although they will be provided to NIH program officers and staff. 1/3

👉️ Are you an undergraduate student interested in genetics? 👉 Do you want to learn how to read a research paper properly? 🪱 Read the #WormBase article in the May issue of #GENETICS, which provides a step-wise guide on understanding a #Celegans study. 🔗 buff.ly/fUkhQum

Dearest shoalmates: Please consider posting a comment to the NIH regarding the Strategic Plan that includes reducing funding for animal research. Responses from the research community are currently greatly underrepresented compared w/ advocacy groups opposing animal experimentation. 🔗 below ⬇️ 1/2

Download our updated database of postdoc fellowships from different foundations and agencies. We identified 275 fellowships. For each entry, we provide description of the fellowship, focus, amount, deadline, eligibility, etc. Download this database here: research.jhu.edu/rdt/funding-...

As one of the postdocs in my lab will be leaving to take a faculty position soon I will likely be placing a new ad in the coming week for someone with experience mapping C. elegans mutants from screens or doing bacterial genetics. If anyone knows/has candidates #Celegans #worms #bacteria #genetics

The Karp lab had a fantastic day at the Midwest C. elegans meeting last week with 6 undergrads and 3 grad students presenting. Thanks to @nickburton.bsky.social and the other organizers for all their work. It’s such a pleasure to get together and talk about science.

Normally non-toxic bacteria, when induced to produce the bioplastic PHB, kill C. elegans! PHB has been in the microbiology text books for over a century — in this new study I co-authored with Gabrielle Giese in the Walhout lab we show this bioplastic is also relevant for host-microbe interactions!

⚒️ NEW TOOLBOX for #Celegans researchers 🪱 Theresa Gibney and Ariel Pani developed a method that allows for a standardized workflow to generate N-terminal and internal tags in any background and without the need for genetic balancers. Paper in #GENETICS:🔗 buff.ly/wXMml3x

It’s great to see our latest microPublication go live! Four undergraduate researchers worked with grad student Kat Yamamoto to demonstrate a correlation between fat storage and survival of #Celegans on pathogenic bacteria! Congrats Alan, Grace, Tiffany, and Daniel! #undergradinthelab #proudPI