Andy Hogan

This should be banned by funders. For one thing it leaks unpublished data to AI companies. And it surrenders judgement which LLMs are terrible at.

MU research led by Dr Ciara Flynn, working within the research group of Prof Andrew Hogan at the Kathleen Lonsdale Institute for Human Health Research has found that obesity can impair key immune cells that help protect the body against infection & cancer. www.maynoothuniversity.ie/news-events/...

Defective Vδ2+ T cell metabolic and functional responses in obesity are can be reversed with bariatric surgery @andyhogan82.bsky.social @maynoothuniversity.ie insight.jci.org/articles/vie...

Defective Vδ2+ T cell metabolic and functional responses in obesity are reversed with bariatric surgery #gdTcells @insight.jci.org

🚨New paper alert!! Out in @insight.jci.org - highlights defects in Vdelta2 T cells in people living with obesity. Importantly we can see bariatric surgery restores these cells!! Led by @ciara.l.flynn but it takes a village. Thanks to funding from HRB. Find it here doi.org/10.1172/jci....

"What people are buying is not what they think it is." RTÉ Prime time on the growing use of peptides and the safety concerns surrounding their use, which features Dr Rob Elmes and Prof Andy Hogan. 📺They will also appear on Prime Time tonight from 9:35 on RTÉ 1. www.rte.ie/news/primeti...

Online Now: The epigenetic and metabolic basis of obesity memory #trends #endocrinology #metabolism

Nanobodies targeting MR1-antigen complexes are engineered to modulate mucosal-associated invariant T cells and target MR1-ligand complexes on tumors www.science.org/doi/10.1126/... @sciimmunology.bsky.social @thedohertyinst.bsky.social

Happy to share our recent findings on the role of MAIT cells in the immunopathogenesis of Staphylococcus aureus infection resulting from the excellent work by Elisa Raineri in my lab: journals.asm.org/doi/10.1128/...

Nice to see @jimmunol.bsky.social highlight this! FYI there is a very nice proteome attached to it

Glycogen & glucose differentially support MAIT cell responses highlight the importance of nutrient availability as a governing signal for MAIT cell fitness @jimmunol.bsky.social academic.oup.com/jimmunol/art... @maynoothuniversity.ie @andyhogan82.bsky.social @eimearrryan.bsky.social

Delighted to share @eimearrryan.bsky.social latest paper out now in @jimmunol.bsky.social showing Rapid glycolytic metabolism underpins mucosal-associated invariant T cell functional responses to innate cytokines academic.oup.com/jimmunol/art...

Online Now: Obesity’s immune memory: an epigenetic barrier to recovery #trends #endocrinology #metabolism

Check out this week's episode featuring Dr. Andrew Hogan at @maynoothuniversity.ie! He discusses how #obesity reshapes the immune system and how #GLP1 therapies are transforming treatment. 🎧 Tune in now: https://bit.ly/3T2vFoL

⌛️ 5 days to go! Submit your abstract for our event with @london-immuno.bsky.social here: vist.ly/59p7t

In #ScienceSignaling, scientists review the latest research about the four factors that support the fitness of mucosal-associated invariant T (MAIT) cells—and discuss findings identifying nutrient availability as a fifth pillar of MAIT cell fitness. https://scim.ag/3Q4akKj

Review @andyhogan82.bsky.social @maynoothuniversity.ie Nutrients are important environmental factors that affect the functional responses of MAIT cells to challenge www.science.org/doi/10.1126/...

🚨 New Publication Alert - out now in @science.org - We outline the environmental regulators of MAIT cells including the nutrients they need - with them coming into focus in cancer this is sure to be important - read it here doi.org/10.1126/scis...

Join us in London this September to explore how environmental signals shape immune responses, with speakers including Yasmine Belkaid, Petter Brodin and more. 📅 Abstract deadline: Monday 29 June 2026 🎟️ Register early to save! Learn more: vist.ly/54ad6

Delighted to share our latest paper out today - led by @ardeena-berisha.bsky.social - we show that we can boost the anti-cancer activity of human MAIT cells by getting them to use lactate & also directing them using bi-specific engagers as a proof of concept academic.oup.com/jimmunol/art...

Delighted to see over review and concept on the cover of this month's @cp-trendsendomet.bsky.social where we cover GLP-1s & SGLT2i as anti-inflammatory agents- co-authored with @nickjonesimmuno.bsky.social

📻 Listen back: Prof Andy Hogan, Dept of Biology, was featured in the Laura Dowling Experience podcast where he discussed his work in immunology, obesity, immune health, GLP-1 therapies, his early life plus much more. open.spotify.com/episode/2ORB...

🧬 Have you submitted your abstract for #UKimmunomet26? The deadline is approaching in 3 weeks! Join the UK’s leading immunometabolism meeting in NCL for cutting edge research, international speakers & sessions for ECRs. Find out more & register 🔗 https://bit.ly/493uE45

****2-NBDG does not measure glucose uptake**** Just your regular reminder of this fact 😁. See the rigorous proof of this fact in @lindavsinclair.bsky.social 2020 paper. This paper was 6 years ago!! Stop using 2NBDG to measure glucose uptake already 🙄 pmc.ncbi.nlm.nih.gov/articles/PMC...

My favourite meeting! Brilliant science and even better community!! Recommend for all from new PhD to old Profs

Registrations are now open for 'Fuelling the immune response', the 4th UK immunometabolism meeting, led by the BSI Immunometabolism Affinity Group. Join us in Newcastle on 16 and 17 April 2026 for cutting edge immune metabolism research #UKimmunomet26 Register here: https://bit.ly/493uE45

Seeking a junior scientist for scRNA-seq analytics in Cologne or remotely. If terms like Seurat, DimPlot, or ggplot2 spark recognition—or curiosity—you might be a fit.Flexible $$ Contract, Part time, MSc-to-PhD transition, or PhD project possible. Please feel free to reach out: triffelm@uni-koeln.de

Studies of T cell acute lymphoblastic leukemia reveal that canagliflozin possesses potent anti-leukaemic effects underpinned by proliferative defects, cell cycle disruption and apoptosis, actions synergized by restriction of serine and glycine www.sciencedirect.com/science/arti...

Compelling metabolic benefits of semaglutide over 30 weeks in patients with schizophrenia Rxed with second-generation antipsychotic agents jamanetwork.com/journals/jam...

MAIT and other innate-like T cells integrate adaptive immune responses to modulate interval-dependent reactogenicity to mRNA vaccines www.science.org/doi/10.1126/... @sciimmunology.bsky.social @aliamini419.bsky.social @thelucygarner.bsky.social @nprovine.bsky.social

The new metabolic medicines #T2D #obesity and #inflammation www.cell.com/trends/endoc...

Delighted to share our new review in @cp-trendsendomet.bsky.social on Repurposing metabolic drugs (GLP-1s & SGLT2s) as anti-inflammatory agents! Thanks to @nickjonesimmuno.bsky.social for this joint effort doi.org/10.1016/j.te...

Delighted to have our latest paper now online in Stem Cell Research & Therapy rdcu.be/ezDs3 Congrats to lead co-first authors @courteney.bsky.social @laurabitterlich.bsky.social and collaborators @james Ankrum @andyhogan82.bsky.social @maynoothuniversity.ie

This was a labor of love requiring lots of teamwork over years, repeating in 3 locations! Thanks to all the lab over the years, giving their time generously to this team project, & our wonderful collaborators. The source of fat matters for anti-tumor immunity 🐄🐖🧈🌴🫒🥥 www.nature.com/articles/s42...

🦠 New research shows obesity disrupts dendritic cell responses to viruses by impairing cytokine production & metabolism - helping explain higher infection risk. 📖 Read the open-access study: https://bit.ly/40kBiiH By @andrea-woodcock.bsky.social‬ et al. #Immunology

Couple of months into our new social media experiment and we are blown away by the engagement - over 2.6 million views on TikTok alone and the daily feedback both online and in person has been so positive and supportive! A whole new way of spreading research based info vm.tiktok.com/ZNdSrMT71/

Our lab @obesityimmunology.bsky.social is looking to support a stellar scientist in their application to the Marie-Sklodowska-Curie European or Global Fellowship to join us to unravel the impact of obesity on the immune system - DM or email andrew.e.hogan@mu.ie for details europa.eu/!B8hjh3

www.tiktok.com/@osheahoganl...

En route home from @kingscollegelondon.bsky.social after 2 days of fantastic science chats! Huge thanks to @peruchalab.bsky.social for the invite and hospitality. Hopefully lots of new collaborations

Obesity is associated with increased susceptibility to infection, which may be due to obesity-induced immune dysregulation. The latest article exchange highlight from @discovimmunol.bsky.social looks at dendritic cell responses to Sendai Virus in a mouse model of diet-induced obesity.

More evidence for GLP-1 medications in limiting rates of cancer. "The findings of this cohort study suggest that GLP-1RAs are associated with reduced risk of developing several hematologic cancers in patients with T2D" jamanetwork.com/journals/jam...

At the Irish Coalition for People living with Obesity's (ICPO) book launch - a child friendly non-stigmatizing introduction to what is Obesity - great initiative

For my immunology followers, the cantrell lab is on bluesky. Applied proteomics, immunometabolism, T cells, protein degradation, signalling what more could you ask for? Give them a follow: @cantrell-lab.bsky.social

Very latest work from @lindavsinclair.bsky.social out today in Nature Immunology www.nature.com/articles/s41...

Changes in body composition following tirzepatide treatment in a substudy of participants from the SURMOUNT-1 trial; the change in body weight, fat mass and lean mass from baseline to Week 72 was −21.3%, −33.9% and −10.9%, consistent across subgroups dom-pubs.onlinelibrary.wiley.com/doi/full/10....

🚨 new paper alert!! Congrats to Andrea Woodcock on delivering this from during the depths of the pandemic! Thanks to @mary-canavan.bsky.social for the collab. Obesity drives dysregulation in DC responses to viral infection academic.oup.com/discovimmuno...

Great new paper from Sandberg group @ki.se in @pnas.org showing IL-10 producing MAIT cells - a population negatively regulated by IL-18 www.pnas.org/doi/10.1073/...

Brilliant presentation from @ArdenaBeirsha from our lab today at #IGCT25 conference @maynoothuni.bsky.social