Bas Bargmann

Bas Bargmann

@bas-bargmann.bsky.social

Associate Professor Virginia Tech School of Plant and Environmental Sciences

201 followers234 following45 posts

Bas Bargmann reposted

#GeneCloud is back 🌱 Our 2015 tool (Mol Plant) that finds the words over-represented in the descriptions of a gene list, rebuilt with @claudeai : 2026 TAIR annotation, exact hypergeometric test + FDR, runs in your browser. πŸ‘‰ gabkrouk.github.io/genecloud/ #PlantScience

Bas Bargmann reposted

The UGA Genetics Department is hiring! Please help spread the word. We have an opening for an Associate Professor/Professor in Genetics, Synthetic Biology, and Biological Engineering. See ad for details – and join us here in Athens, GA!

Bas Bargmann reposted

Are you looking for a postdoc exploring the cell biology of development, defining how cells change shape and move? Do you want to develop a research program & teaching skills preparing you for a position at a college or small University? Our new NIH grant will support those goals 1/n Please share

Lastly, we were also able to visualize the development of transcriptional asymmetry in a growing microcolony. Using a dual auxin- and cytokinin-signaling reporter-gene construct, it was seen that the reporter expression starts to diverge into distinct domains in more mature microcolonies. (10/n)

We also used a Lattice Lightsheet microscope to perform high-temporal resolution live imaging of cultured cells. This set up allowed us to catch a dividing cell in the act. Our favorite is an example showing the microtubule dynamics during the first division of a regenerating protoplast. (8/n)

We managed to capture the donut-shaped structure of microtubules surrounding a phragmoplast forming between two recently separated nuclei. Thanks to Emry Ng for the image processing! (9/n)

We also showcased the use of additional cellular markers, for the Golgi and microtubules. Confocal Z-stacks of developing microcolonies demonstrate the intricate details of intracellular organization of cellular compartments and components during the early stages of regenerative development. (7/n)

Part of the novelty of this method is the embedding of protoplasts in alginate discs that fit into the wells of a 24-well plate. This format β€œenables high throughput experimental design: a single isolation yields more than 24 discs, each potentially representing an independent treatment.” (4/n)

To visualize the development of protoplast regeneration microscopically with enhanced detail and resolution, we incorporate fluorescent cellular markers for the plasma membrane and the nucleus. To better distinguish cell-division events, which can be challenging with brightfield microscopy. (5/n)

It is titled β€œA protoplast-based method to visualize early cell biological events in plant cellular reprogramming and regeneration” and that basically says it all. Nonetheless, I will take this opportunity to walk you through the main points. We also made the cover! #FluorescenceFriday (2/n)

This work was initiated over seven years ago, when Kelsey first started to develop a protoplast regeneration system using Arabidopsis. There were several methods already published, but we struggled to make them work in our hands. We hope that the method used here will be more transferrable. (3/n)

Bas Bargmann reposted

We (Biological Sciences at Virginia Tech) are #hiring TWO tenure-track Molecular Microbiology professors! Review of applications starts 1 Nov. I'm happy to answer questions about the department, VT, life in Blacksburg, etc.! More info / to apply: jobs.apply.vt.edu/jobs/assista... πŸ§ͺπŸ‘©β€πŸ”¬πŸ¦  #academicjobs

jobs.apply.vt.eduAssistant/Associate Professor - Blacksburg, Virginia, United StatesJob Description The Department of Biological Sciences in the College of Science at Virginia Tech seeks applicants for two (2) tenure-track research and teaching positions at the Assistant/Associate ...

Bas Bargmann reposted

🌱We are looking for an Assistant Professor in Plant Molecular Genetics @irbv.bsky.social If you are passionate about genetics, molecular biology, or imaging, this is your chance to join a community of researchers working on plant development, cell biology, evolution, ecology, and biodiversity. πŸ‘‡

rh-carriere-dmz-eng.synchro.umontreal.caCareersThrough your undergraduate and graduate-level teaching, and your research activities, you will contribute to the faculty’s pursuit of excellence. Furthermore, you will promote your discipline and actively participate in the daily activities of a renowned institution.Β As such, you will:

Bas Bargmann reposted

PhD Opportunity at Clemson University! Join our lab to develop cutting-edge AI methods for gene regulatory network inference from single-cell multi-omics data. Research areas include PU Learning, MIL, Flow Matching, and GFlowNets at the intersection of AI and single-cell. Contact me and please RT

Bas Bargmann reposted

Final few days to register for #Auxin2026! ⏰ Registration closes 1st Aug! ⏰ πŸ‘‰ auxin2026.info #plantscience

Association of Applied Biologists@aabiologists.bsky.social

🦞 Auxin biology by the sea 🦞 Not only is Auxin 2026 in a stunning location but we have a fantastic line-up of speakers from around the world 🌍️ Check-out the preliminary programme online now! auxin2026.info

Bas Bargmann reposted

How do transcription factors bind DNA strongly, and in a switch like manner, while remaining sequence specific? Our new paper on a canonical plant TF suggests the answer is a previously underappreciated assembly state: transcription factor nanoclusters. www.science.org/doi/10.1126/...

science.orgNanoclustering of a plant transcription factor enables strong yet specific DNA bindingTranscription factor nanoclusters balance the DNA binding trade-off between weakly binding oligomers and nonspecific condensates.

Bas Bargmann reposted

πŸ”œTwo postdoc positions are available in Rouached Lab for a creative individual to lead a project that will explore a new dimension in the field of plant nutrition. Please contact me if you are interested in TOR signaling, epigenetic and/or plant development rouached@msu.edu

Bas Bargmann reposted

This is going to be so exciting! Reach out with ideas! And come find me at ICAR in Singapore to learn more.

Development@dev-journal.bsky.social

Call for Papers Submit your latest plant and multicellular algae #DevBio research to our upcoming special issue – Plant and Algae Development #DevSIPlantAlgae Editors: @stanfordstomata.bsky.social & Susana Coelho Deadline: 2 November 2026 journals.biologists.com/dev/pages/pl...

Bas Bargmann reposted

An amazing meeting of plant tissue culture enthusiasts. It was inspiring to meet scientists whose publications I have been reading with great interest for years. Congratulations to the organizers for this initiative! Hope to see you again at the next PTCGE conference! 🌱 #PTCGE #tissueculture #NGT

Bas Bargmann reposted

Are you interested in competing in a time-bound event where participants work to design synthetic genetic circuits to program plants with new functions? If so, apply to the SynBio Hackathon! Applications are due June 1, 2026! Apply Here: bit.ly/3QpF5Jr