Interesting Workshop on Antigen Processing and Presentation | 12-15 April 2027 in Greece | With an exciting line-up of experts in MHC biology and antigen processing | Registration is now open: appw2027.org #MHC/#HLA
Tobias Lenz
Tobias Lenz
@biotobi.bsky.social
Professor of Evolutionary Immunogenomics @uni-hamburg.de Evolutionary Genetics, Eco-Immunology, Host-Parasite Coevolution, Evolutionary Medicine, MHC/HLA. Only research-related posts. http://www.biologie.uni-hamburg.de/evolutionaryimmunogenomics
868 followers165 following53 posts
Very interesting paper on variation in promiscuity of #HLA allotypes and its role for immunity, also looking at UKBiobank data | by @matemanc.bsky.social and colleagues | Thanks to @jcwinternitz.bsky.social for sharing www.nature.com/articles/s41...
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Despite frequent inbreeding, banded #mongooses show #MHC diversity on par with species of least conservation concern. New📄Schubert et al. 2025 #BMCEcolEvol provide first full MHC characterization in a wild social #carnivore @bmc.springernature.com #conservationgenetics 👉 doi.org/10.1186/s128...
Interesting paper on #TCR repertoire variation in wild-caught mice. While not controlled for genetics or exposure history, it gives important insights into the extent of variation in a natural setting. academic.oup.com/discovimmuno...
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My postdoc director called my work "phenomenological" and forbade it. I walked to a museum, found Tinbergen had shared a Nobel for work of exactly that kind, and finished the study anyway. On temperament, luck, and what the system selects against 👇 academicrenewal.substack.com/p/a-certain-...
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Pleased to see this beautiful paper out. Kudos to @jeroenmeijer.bsky.social who took @stevenquistad.bsky.social data and dug deep, revealing a new phage that erupts to astonishing abundance. As theory predicts, the life of SGEs is fuelled by encounters with new hosts www.science.org/doi/10.1126/...
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Inaugural post! We are a brand new lab @pasteur.fr studying how pathogen antigens evolve and how we can exploit these proteins' evolution to make better vaccines! Read a few words from the currently sole member of the lab @spyroslytras.bsky.social below! 😁 www.pasteur.fr/en/research-...
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Great experience at #SMBE26 @official-smbe.bsky.social in Copenhagen, where I shared my research on the evolution of HLA diversity in a Native American population. Many thanks to the Ancient and Historical Genomics Symposium and my supervisor @biotobi.bsky.social!
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Researchers in #EvolutionaryBiology & #Ecology wanting to do the right thing? @nicolasgaltier.bsky.social at #SMBE2026 talking about DAFNEE, a database of >600 #ecoevo #evoeco academia-friendly journals for "responsible publishing" - @plos.org seems to do OK here...!
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@acstone.bsky.social getting 2026 #SMBE life time contribution award 😍😍😍🥳🥳🥳🎉🎉🎉🍾🍾🥂🥂🥂 congrats Anne !!!
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Happy to see @arcova.bsky.social from the lab presenting latest results from her study system of Marmosets and Yellow Fever at #SMBE2026
Very proud to see my PhD student @diyarhamidi.bsky.social present at #SMBE2026 about selection on #HLA genes in Native Americans in the context of exposure to novel pathogens due to the invasion by Europeans.
SIP2026 - Where #evolution, #genetics, and #immunology meets! Abstract and early bird deadlines have been extended to June 29! Ever wanted to chat in an informal setting with one (or more) of the folks shown below? Then this is your chance: sip-sassenheim.org Join us in the Netherlands, Nov 2-4
Please share: Abstract deadline approaching (June 15) for the 2026 Annual Symposium of the Society for Immune Polymorphism (Nov 2-4, Netherlands). Intimate community meeting on variation and evolution of immunity and immune genes. Exciting lineup of invited speakers. #MHC #HLA sip-sassenheim.org
Please share: Abstract deadline approaching (June 15) for the 2026 Annual Symposium of the Society for Immune Polymorphism (Nov 2-4, Netherlands). Intimate community meeting on variation and evolution of immunity and immune genes. Exciting lineup of invited speakers. #MHC #HLA sip-sassenheim.org
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📣 EvolDir is now managed by @eseb.bsky.social! We are delighted to be taking the reins and express our gratitude to both Brian Golding who began this service to the community in the mid-1980s and to @rdmpage.bsky.social who ran this account until now 👏 You can now find evoldir here: evoldir.net
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Interested in evolutionary immunogenetics? This is an excellent, small conference bringing together hardcore immunologists and eco-evo people sip-sassenheim.org
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Short time ago, we, the Evolutionary Immunogenomics Research Group, organized the 29th DZG Graduate Meeting in Evolutionary Biology @dzg-evol.bsky.social at the IZS, University of Hamburg @uni-hamburg.de, bringing together early-career researchers for inspiring talks, discussions, and networking.
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Eradicating tumors with a mRNA vaccine in the experimental model www.pnas.org/doi/10.1073/...
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This program transformed my career! Please apply. @hhmi-science.bsky.social's #FreemanHrabowski Scholars Program offers early career faculty up to $10M over 10 yrs, plus salary & benefits. Postdoc? This year's competition has a program for you too. Applications open 11/3! bit.ly/4vhC0LA
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Biologists Confirm Not Much Evolution Happened Today — theonion.com/biologists-c...
We are extending the deadline to Feb 27, since we still have a few slots. 👉 A semi-informal event to interact with your peers, learn about cutting-edge research, and hear from two leaders in the field (Sophie Armitage & Dieter Ebert). And it's free! 🎉 PIs, please recommend to your grad students!
Please share: We are hosting the 2026 DZG evolutionary biology graduate meeting at Uni Hamburg on March 25-27: "Interactions and Coevolution: from Molecules to Species". #PhD students, early postdocs and advanced Master students in evolutionary biology are welcome to register! t1p.de/dzg2026evolbio
Just a quick reminder that the abstract deadline is approaching for the DZG Graduate Meeting in Evolutionary Biology 2026: Feb 20! 👈 We still have a few places left 🤗🌈
Please share: We are hosting the 2026 DZG evolutionary biology graduate meeting at Uni Hamburg on March 25-27: "Interactions and Coevolution: from Molecules to Species". #PhD students, early postdocs and advanced Master students in evolutionary biology are welcome to register! t1p.de/dzg2026evolbio
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Hi yes I will have more to say about this in a few hours but please enjoy this paper. It's been a huge labour of love and effort for the last four years, and a significant part of our research efforts, and I'm so so so thrilled it's finally ready to share. Tldr: scRNA-seq in Indonesia hard but fun
Ancestral and environmental diversity shape the immune landscape in Indonesia https://www.biorxiv.org/content/10.64898/2026.02.15.704933v1
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📢2nd Annual Meeting of the EFIS-IL Sex Differences in Immunity Study Group! 🗓️October 8-9, 2026 📍Hamburg, Germany 🔗https://linktr.ee/EFIS_ISD @yefis-immunology.bsky.social @dgfi-org.bsky.social @sfi-immunologie.bsky.social @swimm-immuno.bsky.social @irishimmunology.bsky.social @finnsocimm.bsky.social
Our second annual meeting - please save the date and distribute
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Our latest review is out, a comprehensive synthesis of #tissue #Tregs. It has been a decade since @annualreviews.bsky.social #immunology last reviewed #TissueTregs, and there have been enormous advances and conceptual leaps forward in the field www.annualreviews.org/content/jour...
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To argue "infections" are an extrinsic factor to heritability is bizarre to me - as if aging takes place in a vacuum. Infections are part of longevity. Infection resistance is heritable (e.g. AMP polymorphisms in mammals, insects). I don't disagree longevity is highly heritable... 1/2
🆕 @science.org Revising the heritability of lifespan, from 25% to ~50%, by correcting for extrinsic factors science.org/doi/10.1126/...
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Deadline for #SMBE2026 abstract submission is coming up (Feb 3)! Consider symposium S14 "Evolution of Host-Pathogen Interactions in the Genomic Age", organized by @jcwinternitz.bsky.social, @arcova.bsky.social, @michalvinkler.bsky.social and @diyarhamidi.bsky.social.
Abstract submission & Award applications for SMBE 2026 are now open! Submit your research and apply for SMBE awards via the submission portal. 📝 Read more & submit here: smbe2026.org/abstracts And symposium selection is now finalized! 👉 See all accepted symposia: smbe2026.org/programme #SMBE2026
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Please share: We are hosting the 2026 DZG evolutionary biology graduate meeting at Uni Hamburg on March 25-27: "Interactions and Coevolution: from Molecules to Species". #PhD students, early postdocs and advanced Master students in evolutionary biology are welcome to register! t1p.de/dzg2026evolbio
It's the annual meeting of the evolutionary biology section @dzg-evol.bsky.social of the German Zoological Society (DZG). Meeting language is English, we welcome participants from all countries and nationalities. Invited speakers are Sophie Armitage (Freie Uni Berlin) and Dieter Ebert (Uni Basel).
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The human pangenome continues to grow and improve! Release 2 is here! Click through for the details, but this is a pretty amazing dataset including not just the phased assemblies, but PacBio HiFi, ONT Ultralong, Dovetail/Illumina Hi-C, PacBio Kinnex, and Illumina WGS for all samples
📢 HPRC Release 2 is here! Now with phased genomes from 200+ individuals, a 5x increase from Release 1. Explore sequencing data, assemblies, annotations & alignments in our interactive data explorer ⬇️: humanpangenome.org/hprc-data-re...
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Replying to @embl.org
Establish your own independent research group as Group Leader - AI in Biology. We’re looking for individuals interested in bridging innovations in machine learning/AI with modern biology. embl.wd103.myworkdayjobs.com/en-US/EMBL/d...
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“Everyone thinks their genes are the cause for them getting an age-related disease, it’s actually your immune system.” - @erictopol.bsky.social the author of Super Agers on #HealthandVeritas podcast pod.link/1588414491/e... @thehowie.bsky.social @hmkyale.bsky.social
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Applications due Monday September 15 for the International Event Grants! These grants support symposia, workshops, courses, and other evolutionary biology events, including virtual events. Learn more and apply now: rb.gy/76fgi
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I've written a short blog post introducing "The Art of Visualization with ggplot2"! This book is all about the end-to-end process of creating charts with #ggplot2 📊 including data wrangling, sketching, and styling your plots! nrennie.rbind.io/blog/art-of-... #RStats #DataViz #TidyTuesday
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📣New today! 📄Haplotype analysis reveals pleiotropic disease associations in the HLA region 🧑🤝🧑 @jkpritch.bsky.social @finngen.bsky.social & colleagues
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Join the annual meeting of the Society for Immune Polymorphism (SIP), November 3-5, Netherlands! A meeting for everyone interested in polymorphic immune molecules (e.g. #MHC/#TCR) and their functional diversity across species. Early bird/Abstract deadline is Aug 15: sip-sassenheim.org
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📣 2 #Immunology #Summer_Schools that might be of interest to you: If you are working on adaptive immune receptor repertoire: ut.ee/en/content/c... If you want to get deeper into new advances in Immunology: focis2025.univ-rouen.fr/page.php?pag... #ImmunoSky
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'Compared with the patients’ doctors, the AI model more often failed to detect the presence of disease in Black patients or women, as well in those 40yrs or younger. Wn the researchers looked at race and sex combined, Black women fell to the bottom, with the AI not detecting disease in half of them'
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Interested in starting your research group in AI and applications to science? Check out our upcoming online event for DFG funded opportunities in Goettingen!
The DFG is funding independent research groups in AI (tinyurl.com/36f5m6kd). If you're interested in coming to Göttingen (Germany) by applying for one of these groups, we have an online event to inform you what the process is and how we could support you (tinyurl.com/yfpeambm). Check it out!
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Your research matters! Contribute to the future of #EvolutionaryBiology by submitting your Abstract to #ESEB2025. 🔬 Explore over 50 topics, including: ✅ #Evolution in all its aspects ✅ #Genetics & #Genomics ✅ New Frontiers and more! 📩 Submit now: eseb2025.com/call-for-abs...
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📢 new paper alert for the primate and genomics nerds. telomere to telomere ape genomes. I led MHC annotations on this work w/ @biotobi.bsky.social and @meyerbritta.bsky.social And hey it’s my first nature paper 🥳 www.nature.com/articles/s41...