Nicolas Fernandez

Place de la Bastille Paris #bike commute #velib

Excited to share our new preprint! 📜 Here, we used CALVADOS and ultra-CG models to show how the kinetochore establishes a robust attachment to the dynamic microtubule end. Spoiler: IDRs 🧵 1/n www.biorxiv.org/content/10.6...

MILK Multi-resolution Integration of Large-scale and high-dimensional Kernel information Biological architecture seems better preserved than UMAP/t-SNE across scales on one hierarchical tree😎 Allow interrogation of different clade sizes along the tree🥸 bioRxiv 2026 www.biorxiv.org/content/10.6...

Me 🤜 🤛 @fmckenna.bsky.social Great long chat about journalism, bonds, repo and all the good stuff. Plus, A Fabulous Debt of course, and why preorders are important (have i mentioned that in the past 24 hours?) thedig.substack.com/p/a-fabulous...

For the Americans whining about gas prices as they constantly keep having to fill up their 4-wheeled tanks for basic participation in society, this is the equivalent of $8.91/gallon. We don't have high gas prices, we have oversized vehicles and no other options in mobility.

better.

Celldega: Integrated Toolkit for Visualization and Analysis of Spatial Data https://www.biorxiv.org/content/10.64898/2026.08.13.744672v1

Another day, another account peddling this bullshit. They don't realize this just permanently entrenches car infrastructure, forced car dependency, and all the waste and pollution that comes with it. Basic critical thinking makes it easy to distinguish greenwashing from actual good policy.

Check out this proof-of-concept website built with Claude that walks through an example multimodal live-cell imaging and Cell Painting workflow from Darian Ventura's (bit.ly/4534nBr) cell motility work cornhundred.github.io/cell_motilit... #celldega #Jupyter #anywidget #CellPainting #cellpose

She can duck and weave, but Susan Collins is the chair of the Senate Appropriations Committee. She’s responsible for overseeing the appropriations process, including funding for ICE. Collins voted in favor of providing $70 billion in additional funding for ICE and Border Patrol. Vote her out.

This is total insanity. Words fail to explain how anyone let alone a plurality of voters thought giving an obviously demented person control of the most powerful government in the world was a good idea. We will be lucky to come out the other side of this alive.

The takeaway for cities: “The best bang for your buck is protected bike lanes,” Moran told Bike Talk‘s Nick Richert. “Really focus on bike infrastructure that’s protected. That’s how you grow ridership. That’s how you diversify ridership.” sf.streetsblog.org/2026/07/08/s...

I, for one, welcome our new gay baseball overlords.

Never forget, a 13-year study found that protected bike-lanes led to a drastic decline in fatalities for all road users. ALL ROAD USERS. What about painted bike-lanes? No safety improvement at all. For sharrows, it’s actually safer to NOT have them. Via @usa.streetsblog.org @nyc.streetsblog.org

“The city’s transition away from the car, tho fantastically chaotic, has become a global role model. Under mayor @annehidalgo.bsky.social, Paris was ‘the most influential city in the world’ says Canadian urbanist Brent Toderian. Hidalgo, stepping down after 12 yrs, exulted: ‘The bike beat the car.’”

To answer everyone's question: Yes, this is bad for the suit, as water can shrink the different layers inside at different rates (face cloth, haircloth, canvas, and padding). If this happens, the damage can't be reversed. That said, I admire his commitment to wearing a suit at all times.

Turkey crossing the bike lane and road 🦃 🚲 #cambridge @cambbikesafety.bsky.social @cambridgemass.bsky.social

​I grew up farming and hold a CDL. I genuinely love semis, heavy machinery, big jets, and rural life. I’m ALSO a bikes-for-transportation advocate, urban infrastructure nerd, and "ban cars" enjoyer. ​I don't normally mix my interests here on Fietser, because...

Pro Tip: Go to every event, extra curricular, school trip you can, do whatever it takes to make that happen. Tuck them in even though you’re tired, play with with them even though you’re busy, hug them even though you’re mad as hell. talk to them even if you’re spent - it goes by so goddamn fast.

"The glee with which Superman carries out his obliteration of the vehicles and the terror of the bystanders is palpable. It all feels like revenge for something." This story features prominently in our book, LIFE AFTER CARS. Superman, welcome to The War on Cars!

About right 🤣

New York Knicks with Zohran Mamdani in City Hall after their NBA Championship parade. Photographed by Ali Imam.

#SUVs: The psychopath's choice. “Buying whatever vehicle we like, and driving it wherever and whenever we please without having to think about the consequences for other people, has become normalised and ingrained across our society over decades." www.theguardian.com/world/2026/j...

There are so many things I love about my town, and our bike traffic signage is definitely one of them. Portland, OR.

I’m sorry, no. This is not the guy who did the reflecting pool. No. Come on. We’re just putting a hat on a hat here. www.nytimes.com/2026/06/18/u...

Timothee Chalamet and Kylie Jenner, welcome to The War on Cars.

We are once again asking Mayor Mamdani... @mayor.nyc.gov

Welcome to the war on cars Boston @thewaroncars.bsky.social - spotted on way to the @humancellatlas.org #HCA2026GM #boston

this is the way

A message for the masses.

Peter Thiel fleeing to Argentina ahh interesting. Grok, has anyone else fled to Argentina in years past?

As the Son of a Dad who owned bodegas for over a decade in the Bronx growing up, I can relate. IT'S AN AWESOME NICKNAME! I did not realize that Bodega Kat is actually part Dominican as his Mom was from the Domican Republic! He obviously has frequented many a "bodega" growing up in Jersey! #BodegaKAT

I can't say enough about the player that Karl Athony Towns, affectionately known as "Bodega KAT", is! The only thing better than his balls skills is the MAN that he is! His upbringing & the passing of his Mom has had a profound impact on his life. He is so well spoken & thankful. God bless you! 🙏✝️

Jeremy Lin's jacket liner has images of Linsanity headlines & magazine covers

just sayin'