Heilemann Lab

Heilemann Lab

@heilemannlab.bsky.social

Single-molecule biophysics group at Goethe University Frankfurt/Germany. Super-resolution microscopy. Optical structural cell biology. Computational microscopy. Posts by MH. http://www.smb.uni-frankfurt.de #superresolution, #livecellimaging, #imageanalysis

650 followers182 following131 posts

Heilemann Lab reposted

🎉 Celebrating the SCALE-it Best PhD Awards 2026! We are proud to celebrate the 2nd SCALE-it Best PhD Awards, honoring outstanding research within the SCALE Cluster! 🏆 Best Scientific Contribution: Dr. Jan Philipp Kreysing (Beck Lab) 🏆 Best Method Development: Dr. Laurell Kessler (Heilemann Lab)

Heilemann Lab reposted

Lead the next discovery at the LMB. We’re recruiting Group Leaders to join our Structural Studies and @cellbiol-mrclmb.bsky.social Divisions. Benefit from long-term support, access to outstanding core-facilities and a collaborative environment where science thrives. ➡️ mrclmb.ac.uk/research-lea...

mrclmb.ac.ukCurious about how life works? | MRC Laboratory of Molecular BiologyThe LMB's Structural Studies and Cell Biology Divisions are each looking for a new Group Leader, at tenured or tenure-track level, to help solve the pu ...

Heilemann Lab reposted

1/5 🚨 🔬 PhD opportunities in my lab at @uni-of-warwick.bsky.social What is the role of plasma membrane organisation in tissue formation? Let’s find out! www.findaphd.com/phds/project... I’m recruiting for several interdisciplinary PhD projects. #PhD #Biophysics #Microscopy ⬇️ Details below 🧵⬇️

findaphd.comThe role of plasma membrane organisation in tissue development at University of Warwick on FindAPhD.comPhD Project - The role of plasma membrane organisation in tissue development at University of Warwick, listed on FindAPhD.com

Heilemann Lab reposted

🔬 super-resolution DNA-PAINT in bacteria requires a labelling method => great work by the Christoph Spahn lab @michriscopy.bsky.social @uni-wuerzburg.de 👉🏻 www.biorxiv.org/content/10.6...

Séamus Holden 🔬🦠🧫@seamusholden.bsky.social

Cool new super-res imaging tools for bacteria from @michriscopy.bsky.social lab! A simple platform for in situ DNA-PAINT optimization enables improved multiplexed super-resolution imaging in Gram-negative bacteria www.biorxiv.org/content/10.6...

Heilemann Lab reposted

Every cell has an organelle signature — a “fingerprint” created from the shape, size, & arrangement of its internal structures. Scientists at our Janelia Research Campus can now read these signatures across 1000s of cells, revealing how tissues adapt to diet & disease bit.ly/4j6DmoH 📹 Feliciano Lab@

Heilemann Lab reposted

Another great example of exchangeable fluorophores prolonging the observation time in microscopy 👇🏻 💪

Sonja Schmid@scisonja.bsky.social

Glad to present #Nanophotonic DyeCycling – #BenjaminVermer’s magnum opus! 🎉 By breaking the longstanding photobleaching limitation in single-molecule #FRET, we achieve longterm observations of conformational #dynamics – gaining >1 order of magnitude more info. www.biorxiv.org/content/10.6...

Heilemann Lab reposted

Georgios Skiniotis and I are announce a unique St. Jude faculty search: a joint effort between the CoE for Structural Cell Biology an intellectual community advancing structural imaging & the Division of Neuronal Cell Biology. CryoET/vEM + neuron cell biology = 🚀 talent.stjude.org/careers/JobD...

talent.stjude.orgFaculty position, Neuronal Cell Biology and Cryo-ET/vEMDepartment of Developmental NeurobiologyCenter of Excellence for Structural Cell Biology and Neuronal Cell Biology DivisionSt. Jude Children’s Research HospitalThe Center of Excellence for...

Heilemann Lab reposted

🔬 Le CRBM fête ses 60 ans avec le Festival de la cellule ! Microscopes, ADN, tardigrades, poisson-zèbre, « bruit des cellules »… Explorez le vivant en famille ! 📅 8 oct. 2026, 10h–19h 📍 Halle Tropisme, Montpellier 🎟️ Gratuit

Heilemann Lab reposted

We are hiring! Start at a #MaxPlanckInstitute with your own independent Max Planck Research Group. This position is equivalent to a W2 Professorship at a German university, or Associate Professor internationally. 🔗Apply until October 14th! www.mpg.de/career/max-p... #ScienceCareer #MPRG #TenureTrack

Heilemann Lab reposted

Heilemann Lab reposted

Open postdoctoral fellow position in our lab on "𝐌𝐨𝐥𝐞𝐜𝐮𝐥𝐚𝐫 𝐇𝐨𝐬𝐭-𝐏𝐚𝐭𝐡𝐨𝐠𝐞𝐧 𝐈𝐧𝐭𝐞𝐫𝐚𝐜𝐭𝐢𝐨𝐧𝐬". Are you interested in macromolecular interactions during host-pathogen interactions both 𝐞𝐱𝐩𝐞𝐫𝐢𝐦𝐞𝐧𝐭𝐚𝐥𝐥𝐲 𝐚𝐧𝐝 𝐜𝐨𝐦𝐩𝐮𝐭𝐚𝐭𝐢𝐨𝐧𝐚𝐥𝐥𝐲? Want to join our team? apply here 👇 ki.varbi.com/what:job/job...

ki.varbi.comPostdoktor i molekylära värd-patogeninteraktionerVill du bidra till medicinsk forskning av toppkvalitet? Vi söker en postdoktoral forskare som kommer att studera makromolekylära interaktioner vid värd-patogeninteraktioner med hjälp av avancerade

Heilemann Lab reposted

Exciting new preprint from Ignacio Vega Vásquez, Sauer lab, my team and collaborators: #Mega-ExM. From just ~20 NPCs imaged with a 10× objective on a confocal, we reconstructed the 3D structure at ~33 Å. A step toward optical structural biology in intact cells. www.biorxiv.org/content/10.6...

Heilemann Lab reposted

👇🏻 don't miss this one if you're into single-molecule microscopy, computational/AI analysis tools and new discoveries in biology 🔬 www.smlms.org

smlms.orgSMLMS 2026 – Stockholm
Ricardo Henriques@henriqueslab.bsky.social

SMLM people, ASSEMBLE!! 🔬 The single-molecule localization crowd descends on Stockholm this August (26-28). MINFLUX, DNA-PAINT, blinking dyes, the lot. Properly good line-up and registration's still open. Don't sit this one out 👇 smlms.org

Heilemann Lab reposted

Excited that our work on versatile and scalable micromirror inserts that enable high-contrast and high-resolution single-objective light sheet microscopy in conventional sample chambers is now published in Nano Letters! doi.org/10.1021/acs.... @pubs.acs.org #soTILT3D #soLLS #microscopy #nanoscale

doi.orgVersatile and Scalable Reflective Micromirrors for Single-Objective Light Sheet MicroscopyWe present a tunable microfabrication pipeline for creating robust, reflective inserts that adapt conventional commercial imaging chambers for single-objective light sheet (LS) illumination. This system reduces the complexity associated with dual-objective LS setups and specialized LS chambers while retaining the native functionality and biocompatibility of the original chambers. The fabricated insert features a metalized, 3D nanoprinted micromirror with an angled reflective surface, enabling alignment of a thin LS for sectioning and imaging throughout mammalian cells. Using this pipeline, we demonstrate that single-objective LS illumination achieves an over 4X improvement in the signal-to-background ratio compared with conventional widefield epi-illumination in both fixed and live cell samples. Furthermore, we show substantial resolution enhancement for single-molecule localization microscopy compared to epi-illumination for improved imaging at the nanoscale. The versatile and scalable design offers an easily implemented approach to bring the benefits of single-objective LS microscopy to a wide array of biological studies.

Heilemann Lab reposted

Seeking a post-doc for the LaJoie lab at the Human Technopole, Milan, Italy! We are looking for candidates from the fields of biochemistry, cell biology, and proteomics, who are interested in studying protein interactions of the nucleus 🤓 lnkd.in/dTG2CgXF

Heilemann Lab reposted

📢 We are looking for a Junior Group Leader to join us at @institutcurie.bsky.social! Having joined the department just over a year ago, I can honestly say that it is an exceptionally stimulating and supportive scientific environment, filled with outstanding colleagues — all in the heart of Paris.

Heilemann Lab reposted

🚨Our #NIMSB PhD fellowship call closes on Friday! We're recruiting for 5 fantastic PhD projects + welcome applicants from diverse backgrounds: #biologists #computerscientists #physicists #engineers If you want to work on cutting-edge science, we'd love to hear from you 🚀 👉https://sl1nk.com/vog901g

Estibaliz Gómez de Mariscal, PhD@gomez-mariscal.bsky.social

Want to do a PhD in biomedical research and explore the exciting world of AI, microscopy and cell biology?👾🧠🧫🔬 In a research environment of high excellence🌟 and in beautiful Portugal🏄🌸? PhD fellowships are now open at #NIMSB from May-4 til June-5 👉 APPLY lnkd.in/eqkYreFi Reach out if interested!✉️

🔬👇🏻 cannot resist to re-advertise this meeting ... because it's just a great one.

SMLMS 2026@smlms2026.bsky.social

🚨 Don't forget about our submission deadlines! Register now at smlms.org and don't miss the opportunity to connect with the SMLM community in Stockholm this summer.