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Heilemann Lab
Heilemann Lab
@heilemannlab.bsky.social
Single-molecule biophysics group at Goethe University Frankfurt/Germany. Super-resolution microscopy. Optical structural cell biology. Computational microscopy. Posts by MH. http://www.smb.uni-frankfurt.de #superresolution, #livecellimaging, #imageanalysis
650 followers182 following131 posts
Heilemann Lab reposted
🎉 Congratulations to Laurell Kessler for the PhD Award for Best Method Development from our EXC SCALE! @scale-cluster-ffm.bsky.social @goetheuni.bsky.social Laurell developed a smart STED microscope and visualized the RNA-guided structure of a nuclear condensate in cells 👉🏻 doi.org/10.1038/s414...
Heilemann Lab reposted
Lead the next discovery at the LMB. We’re recruiting Group Leaders to join our Structural Studies and @cellbiol-mrclmb.bsky.social Divisions. Benefit from long-term support, access to outstanding core-facilities and a collaborative environment where science thrives. ➡️ mrclmb.ac.uk/research-lea...
Heilemann Lab reposted
1/5 🚨 🔬 PhD opportunities in my lab at @uni-of-warwick.bsky.social What is the role of plasma membrane organisation in tissue formation? Let’s find out! www.findaphd.com/phds/project... I’m recruiting for several interdisciplinary PhD projects. #PhD #Biophysics #Microscopy ⬇️ Details below 🧵⬇️
Heilemann Lab reposted
Our Department of Developmental & Cell Biology @ucirvine.bsky.social is looking for a Professor & Chair! Join our diverse and collegial team in the premier UC public system. Dept: devcell.bio.uci.edu Details: recruit.ap.uci.edu/JPF10452
🔬 super-resolution DNA-PAINT in bacteria requires a labelling method => great work by the Christoph Spahn lab @michriscopy.bsky.social @uni-wuerzburg.de 👉🏻 www.biorxiv.org/content/10.6...
Cool new super-res imaging tools for bacteria from @michriscopy.bsky.social lab! A simple platform for in situ DNA-PAINT optimization enables improved multiplexed super-resolution imaging in Gram-negative bacteria www.biorxiv.org/content/10.6...
Heilemann Lab reposted
Every cell has an organelle signature — a “fingerprint” created from the shape, size, & arrangement of its internal structures. Scientists at our Janelia Research Campus can now read these signatures across 1000s of cells, revealing how tissues adapt to diet & disease bit.ly/4j6DmoH 📹 Feliciano Lab@
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We have a position open in our core facility in the @pasteur.fr . Please share it and / or apply! forum.image.sc/t/research-e...
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🧑🎓 Calling aspiring #PhD students: Now is a good time to apply to the PhD school of the @nanoscience.ch @unibas.ch Switzerland: #Nanopore detection of metal- #nanocluster heterogeneity with single-molecule resolution. nanoscience.unibas.ch/fileadmin/us...
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📢 We’re hiring! PNI is seeking a full-time Lecturer in Computational and Cognitive Neuroscience to teach undergraduate and graduate courses in computational modeling and human cognitive neuroscience. Priority consideration: Nov. 30 Apply: apply.interfolio.com/193741 #NeuroSkyence #NeuroJobs
Heilemann Lab reposted
(Part 1/2) Excited to share our recent work with Prof. Nicolas Fawzi’s group (nicolasluxfawzi.bsky.social), now out in Angewandte Chemie (onlinelibrary.wiley.com/doi/full/10....)! We show how RNA reshapes FUS condensate assembly and dynamics. Congrats to Tongyin, Kandarp, Samara, Qizan, Priyesh!
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Yet another opportunity @dunnschool.bsky.social! We are looking for an Associate Professor If you have exciting research plans, @dunnschool.bsky.social is a great place: excellent science (and lovely people, obvs) www.path.ox.ac.uk/vacancy/asso...
Another great example of exchangeable fluorophores prolonging the observation time in microscopy 👇🏻 💪
Glad to present #Nanophotonic DyeCycling – #BenjaminVermer’s magnum opus! 🎉 By breaking the longstanding photobleaching limitation in single-molecule #FRET, we achieve longterm observations of conformational #dynamics – gaining >1 order of magnitude more info. www.biorxiv.org/content/10.6...
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🚨I have open PhD positions in my new lab at #NIMSB🚀!! Deadline Oct-16 nimsb.unl.pt/join-us/ 🌟I'm looking for motivated candidates who are eager to join a highly multidisciplinary team and study the intracellular dynamics of cancer cell migration using advanced computational methods and microscopy👾
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Georgios Skiniotis and I are announce a unique St. Jude faculty search: a joint effort between the CoE for Structural Cell Biology an intellectual community advancing structural imaging & the Division of Neuronal Cell Biology. CryoET/vEM + neuron cell biology = 🚀 talent.stjude.org/careers/JobD...
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In-cell structures visualize human pre-ribosome assembly in the nucleolus | Science www.science.org/doi/10.1126/...
Heilemann Lab reposted
Do peptide–MHC I complexes cluster on the cell surface? We counted them, one by one. Picomolar soluble TCRs + #DNAPAINT on primary human dendritic cells: pMHC I is monomeric. No nanoclusters. What is regulated instead: surface density, and where complexes sit. doi.org/10.1073/pnas.2615838123
👉🏻 this project was driven — enthusiastically and excellently — by Olivia Jacobs (Robert Tampé group) and Tanja Menche @heilemannlab.bsky.social, and in collaboration with TRON Mainz. @goetheuni.bsky.social @scale-cluster-ffm.bsky.social @crc1507.bsky.social #DNAPAINT #superresolution #MHC
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Incredibly happy to share the first publication from our lab, now published in Nature Cell Biology! 🎉 How do cells coordinate RNA processing with nuclear organization and the cell cycle? www.nature.com/articles/s41...
Heilemann Lab reposted
We are hiring! Start at a #MaxPlanckInstitute with your own independent Max Planck Research Group. This position is equivalent to a W2 Professorship at a German university, or Associate Professor internationally. 🔗Apply until October 14th! www.mpg.de/career/max-p... #ScienceCareer #MPRG #TenureTrack
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Check this exciting study from @gabrijelad.bsky.social and colleagues: www.nature.com/articles/s41...
Heilemann Lab reposted
Please spread the news - the Department of Neurobiology at UCLA is hiring. This is an open rank search for all and any amazing neuroscientists! Please apply here by Nov 15th, first review end of October : recruit.apo.ucla.edu/JPF11296
Heilemann Lab reposted
We’re hiring! Experimental #Postdoc and computational and/or experimental #PhD positions in evolutionary genomics are available in our lab in Heidelberg: home.kaessmannlab.org/openPositions Please repost and spread the word!
Heilemann Lab reposted
🚨 I AM HIRING a 3-year postdoc & 4-year PhD student 🚨 [PLEASE SHARE WIDELY] My Emmy Noether @dfg.de funded Neural Circuit & Systems Evolution lab (🌟) at the @unimainz.bsky.socialÍ wants to start existing. So..., what do we need? WELL... we need you! APPLY UNTIL 21 SEPTEMBER.
Heilemann Lab reposted
Open postdoctoral fellow position in our lab on "𝐌𝐨𝐥𝐞𝐜𝐮𝐥𝐚𝐫 𝐇𝐨𝐬𝐭-𝐏𝐚𝐭𝐡𝐨𝐠𝐞𝐧 𝐈𝐧𝐭𝐞𝐫𝐚𝐜𝐭𝐢𝐨𝐧𝐬". Are you interested in macromolecular interactions during host-pathogen interactions both 𝐞𝐱𝐩𝐞𝐫𝐢𝐦𝐞𝐧𝐭𝐚𝐥𝐥𝐲 𝐚𝐧𝐝 𝐜𝐨𝐦𝐩𝐮𝐭𝐚𝐭𝐢𝐨𝐧𝐚𝐥𝐥𝐲? Want to join our team? apply here 👇 ki.varbi.com/what:job/job...
🚨 2x PhD opportunities: single-molecule/super-resolution microscopy & image analysis of membrane proteins 🔬(DM for details) 👉🏻 tinyurl.com/5dt7ncby 👉🏻 tinyurl.com/5e52dth2 🙏 Dear colleagues & friends, pls distribute - Thank you! 🙏 @crc1507.bsky.social imol.uni-frankfurt.de @goetheuni.bsky.social
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Exciting new preprint from Ignacio Vega Vásquez, Sauer lab, my team and collaborators: #Mega-ExM. From just ~20 NPCs imaged with a 10× objective on a confocal, we reconstructed the 3D structure at ~33 Å. A step toward optical structural biology in intact cells. www.biorxiv.org/content/10.6...
🔬Check out this clever approach for 3D SMLM by Yoav Shechtman @technion.bsky.social and @gustavssonlab.bsky.social ... stunning images! 👉🏻 doi.org/10.64898/202...
Heilemann Lab reposted
Excited to see this collaboration now in print. Dye chemistry meets AI-designed proteins. Three small, orthogonal tags; lifetime modulation; split versions. Request the free dyes at dyes.janelia.org www.science.org/doi/10.1126/...
Heilemann Lab reposted
We're thrilled to unveil our fantastic line-up of selected speakers for SMLMS 2026 at smlms.org Huge congratulations to them! 🎉 Missed the deadline? Good news! Registration and poster abstract submission have been extended until 31st July! 🔬✨
Heilemann Lab reposted
🚀 We're hiring! Join the founding Digital Twin Team at the SCALE Cluster of Excellence @goetheuni.bsky.social Apply by: 31 August 2026 For more information: scale-frankfurt.org/wp-content/u... Full position description: scale-frankfurt.org/wp-content/u... Descriptions below 🧵:
Heilemann Lab reposted
Heilemann Lab reposted
Interested in RNA and proteins? Perfect! 😀 We seek to fill a fully funded 3+ years PhD position for a project on pre-mRNA splicing regulation using structural biochemistry in combination with cell biology and bioinformatics. Find more information on our lab's homepage and get in contact via e-mail!
Heilemann Lab reposted
Interested in single molecule localisation microscopy? 🔬 Don't miss #SMLMS2026, hosted in by SciLifeLab, KTH and Stockholm University, with contributions from our Swedish NMI Node colleagues! 🗓️ August 26-28 in Stockholm 🇸🇪 More⤵️ smlms.org
👇🏻 don't miss this one if you're into single-molecule microscopy, computational/AI analysis tools and new discoveries in biology 🔬 www.smlms.org
SMLM people, ASSEMBLE!! 🔬 The single-molecule localization crowd descends on Stockholm this August (26-28). MINFLUX, DNA-PAINT, blinking dyes, the lot. Properly good line-up and registration's still open. Don't sit this one out 👇 smlms.org
Heilemann Lab reposted
How can a splicing factor bind to thousands of exons but regulate only a few of them? In our new preprint, we show that SRSF6 resolves this paradox through two distinct binding modes. @lab-nmr.bsky.social & @julianvonehr.bsky.social. Check it out: www.researchsquare.com/article/rs-9...
Heilemann Lab reposted
WORK: our Bionanoscience department at TU Delft is looking to hire an Assistant Professor in Biophysics of Living Systems. Apply! Deadline 30 July careers.tudelft.nl/job/Delft-As... RT=nice
Heilemann Lab reposted
Just in time for the RNA localisation conference, we uploaded a manuscript describing the link between endosomal mRNA transport and local mitochondrial activity. Great collaboration during MibiNet www.biorxiv.org/cgi/content/... @mibinet.bsky.social #EMBOrnaLocalization
Heilemann Lab reposted
Excited that our work on versatile and scalable micromirror inserts that enable high-contrast and high-resolution single-objective light sheet microscopy in conventional sample chambers is now published in Nano Letters! doi.org/10.1021/acs.... @pubs.acs.org #soTILT3D #soLLS #microscopy #nanoscale
Heilemann Lab reposted
Seeking a post-doc for the LaJoie lab at the Human Technopole, Milan, Italy! We are looking for candidates from the fields of biochemistry, cell biology, and proteomics, who are interested in studying protein interactions of the nucleus 🤓 lnkd.in/dTG2CgXF
Heilemann Lab reposted
Make HDAC6 visible again! 6SiR-C3-NextA is a selective far-red probe for imaging endogenous HDAC6 in living cells across diverse mammalian cell types. Done by @vanthang.bsky.social at @mpi-nat.bsky.social Now in JACS @pubs.acs.org pubs.acs.org/doi/10.1021/...
Heilemann Lab reposted
📢 We are looking for a Junior Group Leader to join us at @institutcurie.bsky.social! Having joined the department just over a year ago, I can honestly say that it is an exceptionally stimulating and supportive scientific environment, filled with outstanding colleagues — all in the heart of Paris.
Heilemann Lab reposted
Want to build some of the most advanced light-sheet microscopes in the world to watch life assemble itself cell by cell? The Royer Lab @ Biohub is hiring an Optical Engineer (Advanced Light Sheet Microscopy). 🧪🔬💻🔧 #Hardware + #Python + Advanced #Optics job-boards.greenhouse.io/biohub/jobs/...
Heilemann Lab reposted
🚨Our #NIMSB PhD fellowship call closes on Friday! We're recruiting for 5 fantastic PhD projects + welcome applicants from diverse backgrounds: #biologists #computerscientists #physicists #engineers If you want to work on cutting-edge science, we'd love to hear from you 🚀 👉https://sl1nk.com/vog901g
Want to do a PhD in biomedical research and explore the exciting world of AI, microscopy and cell biology?👾🧠🧫🔬 In a research environment of high excellence🌟 and in beautiful Portugal🏄🌸? PhD fellowships are now open at #NIMSB from May-4 til June-5 👉 APPLY lnkd.in/eqkYreFi Reach out if interested!✉️
Heilemann Lab reposted
Thousandfold Expansion Microscopy https://www.biorxiv.org/content/10.64898/2026.05.31.729018v1
Heilemann Lab reposted
We enjoyed putting our heads together with the Jakob and Freddolino labs to find that polyphosphate modulates the formation of functional RNA-protein condensates in response to nitrogen-starvation stress! journals.plos.org/plosbiology/...