Krissy Lyon

Krissy Lyon

@krissylyon.bsky.social

Neuroscientist & astrocyte enthusiast | Postdoc in the Allen lab @SalkInstitute.bsky.social | NINDS K99 | @lclark.bsky.social and Harvard PiN alum | she/her

1.3K followers978 following91 posts

Krissy Lyon reposted

We will be hosting 4th Full Circle Symposium for Native Biologists hosted at UCSF in May 2027! We aim to build community and provide meaningful opportunities for Native scientists. If you are a Native biologist at any training stage who wants to speak, plz fill this out by this 1/31: bit.ly/4kh5GFx

Krissy Lyon reposted

Hi all, I'm happy to announce that I have started at the University of Oregon as an assistant professor! My group will use computational methods to study learning and synaptic plasticity. I will be hiring grad students this year--please reach out if you're interested! colinbre@uoregon.edu

Krissy Lyon reposted

We are thrilled to announce our 2026 cohort of P-SPINE Fellows! Thank you to everyone who applied this year - the applications were truly impressive. Come join us on October 28th to hear from these amazing postdocs and to network with the Philly neuro community!

Krissy Lyon reposted

The Nano Lab is opening in the Dept. of BioSciences, Rice University, Oct 2026! 🧠🦉 We’ll be profiling and perturbing the molecular cues that shape the human brain using single-cell functional genomics and cortical organoids.

Krissy Lyon reposted

Krissy Lyon reposted

Super stoked to share that I’m starting my lab at UHN @dkjei-uhn.bsky.social / @kbi-uhn.bsky.social and the University of Toronto! If you’re interested in neuron-myelin interactions in circuit maturation and cognition, please reach out - we are hiring! www.oligodendrocyte.org 1/

oligodendrocyte.orgXin LabWelcome! We study the cellular interactions between neurons and oligodendrocytes, which produce myelin in the central nervous system. Myelination - the process by which oligodendrocytes ensheath neuro...

Krissy Lyon reposted

Excited to share that I joined the Institute of Psychiatry and Neuroscience of Paris @ipnp.bsky.social as a group leader! Thank you to FRM and BBRF for the support! My team will study how dedicated neural circuits decode seasonal changes, and drive adaptive behaviors. 🧠 ☀️ ❄️

Krissy Lyon reposted

Very excited to share our new manuscript – published today! Why are PIEZO1 and PIEZO2 are tuned to transduce different types of mechanical force? I was lucky to work with some extraordinary colleagues to begin to figure out why. www.nature.com/articles/s41... An overview of the results below ⬇️ ⬇️

nature.comThe molecular basis of force selectivity by PIEZO2 - NaturePIEZO2 is intrinsically more rigid than PIEZO1, and disparate mechanical stimuli paradoxically evoke opposite conformational and gating responses in each channel.

Krissy Lyon reposted

New paper from the lab led by @ericmulhall.bsky.social addresses how PIEZO1 and PIEZO2 are tuned to different types mechanical forces. From nanometer-scale super-resolution microscopy to in vivo experiments, links single-molecule observations to physiological function. www.nature.com/articles/s41...

nature.comThe molecular basis of force selectivity by PIEZO2Nature - PIEZO2 is intrinsically more rigid than PIEZO1, and disparate mechanical stimuli paradoxically evoke opposite conformational and gating responses in each channel.

Krissy Lyon reposted

Krissy Lyon reposted

If you are submitting an NIH grant in February, you will be required to use SciENcv to prepare you biosketch. IT IS MUCH WORSE THAN YOU CAN POSSIBLY IMAGINE. Set aside *at least* 4 hours just to transfer an existing an biosketch into SciENcv.

Krissy Lyon reposted

WOW! 372 "astrocyte" presentations this year at #SfN2023 @SfNTweets Not enough talks - let's work on this for 2024. Full roundup below. I am SURE I have missed some, so please reply with more! Daily session roundups to come for each session. See you all soon. #SocietyForGlia

If you will be at #SfN25 next week, please join us for a professional development workshop ‘Navigating your career roadmap in a changing landscape’ on Monday from 12-2. Led by THE Dr. Michelle Jones-London. Please share with your lab and anyone you think would benefit!

Krissy Lyon reposted

If you are attending #SfN25, please join @amygleichman.bsky.social and I on Monday at 9PM for a casual social gathering to discuss all things non-neuronal! Date: Monday, Nov 17th Time: 9PM till close Location: The Smoking Gun SD, 555 Market St. All welcome, please free to spread the word!

Krissy Lyon reposted

Edward Kravitz, a Harvard biochemist who proved GABA's inhibitory power, passed away last month. He will "be remembered for his humanity, for his social conscience and his desire to help those less fortunate than he,” says Ronald Harris-Warrick. By @claudia-lopez.bsky.social bit.ly/479Ggmo

bit.lyRemembering GABA pioneer Edward KravitzThe biochemist, who died last month at age 92, was part of the first neurobiology department in the world and showed that gamma-aminobutyric acid is inhibitory.

Krissy Lyon reposted

It is based on a word cloud from the titles of the 197 MOSAIC grantee projects. I had it made if I have testify in the grant delay trial but it was perfect for this occasion. Who needs PowerPoint?

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Krissy Lyon reposted

Lab’s 1st preprint! Menstruation is understudied due to societal taboos + a biological challenge: mice (a key system for research + drug discovery) don’t menstruate. @cagricevrim.bsky.social made menstruating mice + used them to discover early events in menstruation. He is on the job market!

Çağrı Çevrim@cagricevrim.bsky.social

I’m thrilled to share my postdoc work and the first paper from the McKinley Lab! 🎉 @karalmckinley.bsky.social We built the first transgenic model of menstruation in mice. We used it to uncover how the endometrium organizes and sheds during menstruation. 🧪 www.biorxiv.org/content/10.1... 🧵

Krissy Lyon reposted

A huge shoutout to all the dedicated grants management specialists at the NIH who are working around the clock to push grants out before the Sep 30 deadline. And also to the POs responding to frantic emails. Not an easy job under the best of circumstances and right now it's the pits. Thank you!

Krissy Lyon reposted

Over 20 years after Julius’s lab and mine cloned TRPM8, it is rewarding to see this science helping patients. The TRPM8 agonist Tryptyr treats dry eye by increasing tear production. A reminder that NIH-funded curiosity-driven research translates to medicines. tryptyr.myalcon.com?gad_source=1...

tryptyr.myalcon.comTRYPTYR (acoltremon ophthalmic solution) 0.003% eye drops | Alcon USTRYPTYR is a prescription eye drop used for the treatment of the signs and symptoms of dry eye disease. See prescribing information, how to save, and more.

Krissy Lyon reposted

FlyBase, a Drosophila database, will lose a third of its team in early October because the Harvard grant that covered the employees’ salaries was canceled. Scientists warn that losing FlyBase could devastate fly research. By @claudia-lopez.bsky.social www.thetransmitter.org/community/ha...

thetransmitter.orgHarvard University lays off fly database teamThe layoffs jeopardize this resource, which has served more than 4,000 labs for about three decades.

Excited to have received the NOA for my K99 Pathway to Independence award on astrocytes in neurodevelopmental disorders! I am so grateful for my PI Nicola Allen, and all my mentors, letter writers, and collaborators.

Krissy Lyon reposted

Krissy Lyon reposted

don't be fooled that this NIH effort is only about NOFO - listen to minute 21-22 "they are working tirelessly" to "phase out" "existing" funding www.youtube.com/watch?v=iSvk...

youtube.comDirector’s Desk: The Future of Animal Models in Research | NIH’s Dr. Nicole KleinstreuerYouTube video by National Institutes of Health (NIH)
Dr. Rabbithole@drrabbithole.bsky.social

Good news - it appears that the requirement for non-animal models is at the NOFO level. This just means NIH can't solicit for only animal research grants - other approaches must be considered. This is actually a totally reasonable policy!

Congratulations to all the new awardees!! Happy to see this program ongoing!

Burroughs Wellcome Fund@bwfund.bsky.social

BWF is proud to announce the 2025 recipients of its Postdoctoral Diversity Enrichment Program (PDEP), which provides critical support to postdoctoral researchers pursuing careers in biomedical and medical research. www.bwfund.org/news/bwf-ann... #bwfpdep

Krissy Lyon reposted

In this entire 4.5 hour video from the FDA and NIH about reducing animal models, I didn't hear any discussion about conducting research developing new treatments for mental health disorders with behavioral symptoms

Alexander Harris@dralexharris.bsky.social

At 2:38:55 of this video is when the NIH component of the workshop begins. 2:49:11 is where the announcement of no new NIH funding of proposals relying exclusively on animals youtube.com/live/vz1uF42...

Krissy Lyon reposted

I'll be presenting at this science fair: I've done many a poster presentation, but never one quite like this!

Dr. Rabbithole@drrabbithole.bsky.social

A science fair of cancelled grants. The research that will be represented at this event (Tuesday) ranges from neuroscience, to astrophysics, to STEM education. The awarding agencies of the now-canceled grants include the EPA, DHS, NIH, NSF, USAID, and DOD. Open to the public.

Krissy Lyon reposted

BREAKING: Scientists are staging a “science fair” in the lobby of a Congressional building to tell elected officials about the critical knowledge the US will lose because their research grants have been canceled.